This file reviews materials in Exercises 1416 & prepares you for the lab practical. In this file, required structures are highlighted, checked, or specified, sometimes in different colors. by Dr. Shaw, Zoology 251 Lab Coordinator, x7176; donalds@utm.edu 1 Ex. 14 Histology of the nervous system 2 The nervous system Central nervous system (CNS) Peripheral nervous system (PNS) Brain Nerves Spinal cord Ganglia 3 Neuroglia of the central nervous system Capillary Neurons Astrocyte Perivascular feet Myelin (cut) Cerebrospinal fluid Microglia Ependymal cell Oligodendrocyte 4 Complete the following table Types of glial cells in the CNS Functions Astrocytes Oligodendrocytes Ependymal cells Microglia Practice 5 A Schwann cell of the PNS Schwann cell Axon Basal lamina Endoneurium Nucleus Neurilemma Myelin sheath 6 A neuron Dendrites Soma (Cell body) Axon hillock Axon collateral Axon Direction of signal transmission Internodes Node of Ranvier Myelin sheath Schwann cell Axon terminals 7 A neuron; ID the indicated structures Practice 8 Nissl bodies, stained masses of rough ER Nissl bodies Axon hillock 9 Structure of a chemical synapse Microtubules of cytoskeleton Axon of presynaptic neuron Mitochondria Synaptic knob Postsynaptic neuron Synaptic vesicles with neurotransmitter Synaptic cleft Neurotransmitter receptor Postsynaptic neuron Neurotransmitter release 10 A chemical synapse; ID the indicated structures Microtubules of cytoskeleton Axon of presynaptic neuron Postsynaptic neuron Neurotransmitter receptor Postsynaptic neuron Practice Neurotransmitter release 11 Neuromuscular junction (LM) Motor nerve fibers Axon terminal; Neuromuscular junction Muscle fibers 100 m 12 Tract and cross section of the spinal cord Ganglion (cell bodies found in the PNS); Posterior root ganglion Ascending tracts Descending tracts White matter (due to myelination), composed mostly axons Tracts (bundles of axons found in the CNS; carry signals from one part of the CNS to another) Gray matter (clusters of cell bodies) 13 Anatomy of a ganglion Spinal cord Direction of signal transmission Posterior root ganglion To peripheral To spinal cord receptors and effectors Posterior root ganglion Anterior root Somatosensory neurons Sensory pathway Spinal nerve (mixed nerve) containing sensory and motor fibers Posterior root Epineurium Blood vessels Anterior root Sensory (afferent) nerve fibers: carry nerve impulses toward the CNS Motor pathway Motor (efferent) nerve fibers: carry nerve impulses away from the CNS 14 Anatomy of a nerve Spinal nerve Epineurium Blood vessels Fascicle Perineurium Endoneurium 15 Anatomy of a nerve; ID the indicated structures Spinal nerve Blood vessels Practice 16 A cross section of a nerve (SEM) Epineurium Perineurium Endoneurium Nerve fiber Fascicle Blood vessels 17 Ex. 15 Gross anatomy of the brain 18 Surface anatomy of the brain, superior view Cerebral hemispheres Frontal lobe Central sulcus Parietal lobe Occipital lobe Longitudinal fissure 19 Surface anatomy of the brain, left lateral view, with the brainstem in orange Rostral Caudal Central sulcus Gyri Cerebrum Lateral sulcus Temporal lobe Cerebellum Brainstem Spinal cord 20 Lobes of the cerebrum Rostral Caudal Frontal lobe Parietal lobe Postcentral gyrus (Primary somatosensory cortex) Precentral Gyrus (primary motor area) Parieto-occipital sulcus Central sulcus Occipital lobe Insula Lateral sulcus Temporal lobe 21 The cerebrum; ID the indicated structures Rostral Caudal Insula Practice 22 Functional regions of the cerebral cortex Precentral gyrus (Primary motor Cortex) Motor association area Broca area (motor speech region) Prefrontal Cortex (complex reasoning & personality) Olfactory association area Postcentral gyrus (Primary somatosensory cortex Somatosensory association area Primary gustatory cortex Wernicke area (speech is understood here) Visual association area Primary visual cortex Primary auditory cortex Auditory association area 23 Functional regions of the cerebral cortex; ID the indicated structures Motor association area Primary gustatory cortex Visual association area Primary visual cortex Olfactory association area Primary auditory cortex Auditory association area Practice 24 Ventral view of sheep brain-01 Required structures are checked. 25 Ventral view of sheep brain-02 Required structures are checked. 26 Ventral view of sheep brain-03 Structures in bold and underlined are required. 1—Cerebrum; 2—Cerebellum; 3—Medulla oblongata; 5—Pons; 6—Infundibulum; 7—Mammillary body; 8—Spinal cord; 9—Optic chiasm; 10—Olfactory bulb I—Olfactory N. II—Optic N. V—Trigeminal N. Practice 27 Posterior view of sheep brain-01 Required structures are checked. Midbrain includes superior and inferior colliculi 28 Posterior view of sheep brain-02 Required structures are checked. Midbrain (superior & inferior colliculi) 29 Dorsal view of sheep brain-01 Required structures are checked. 30 Dorsal view of sheep brain-02 Structures in bold and underlined are required. A—Longitudinal fissure; B– Central sulcus; C—Frontal lobe; D—Parietal lobe; E—Occipital lobe; F—Temporal lobe; G—Cerebellum; H—Vermis; I—Medulla oblongata Practice 31 Sagittal view of sheep brain-01 Required structures are checked. 32 Sagittal view of sheep brain-02 All structures are required except two that are crossed out. Practice—KEY (next slide) 33 Sagittal view of sheep brain-03 All structures are required except infundibulum & fornix (crossed out). KEY 34 Ventricles of the human brain, lateral view Caudal Rostral Lateral ventricles Interventricular foramen Third ventricle Cerebral aqueduct Fourth ventricle Lateral aperture Median aperture Central canal (a) Lateral view 35 Coronal view of sheep brain Structures in bold & underlined are required. 2—Lateral ventricle; 3—Third ventricle; 4—Cerebral aqueduct; 6—Pons; 23—Longitudinal fissure; 24— Cerebral cortex; 25—Cerebral white matter; 26—Choroid plexus Practice 36 Coronal view of human brain Cerebrum Corpus callosum Lateral ventricle Thalamus Internal capsule Caudate nucleus Insula Putamen Third ventricle Globus pallidus Hypothalamus Subthalamic nucleus Optic tract Basal ganglia/nuclei Pituitary gland 37 Cerebral cortex histology Required structures are checked. (Triangular shape) (Triangular shape) 38 Cerebellum histology A Purkinje cell (large & globosely) A Purkinje cell’s dendrites compressed into a single plane like a flat tree. 39 Ex. 16 Cranial nerves 12 pairs of peripheral nerves connected to the base of the brain Originate in or near the brain Functionally they are sensory (three pairs; CN I, II, and VIII), motor, or mixed nerves 40 Cranial nerves mnemonic 01 Oh Once One Takes The Anatomy Final, Very Good Vacations Seem Heavenly. Olfactory (I) Optic (II) Oculomotor (III) Trochlear (IV) Trigeminal (V) Abducens (VI) Facial (VII) Vestibulocochlear (VIII) Glossopharyngeal (IX) Vagus (X) Spinal accessory (XI) Hypoglossal (XII) 41 Cranial nerves mnemonic 02 Old Opie Occasionally Tries Trigonometry And Feels Very Gloomy, Vague, And Hypoactive. Olfactory (I) Optic (II) Oculomotor (III) Trochlear (IV) Trigeminal (V) Abducens (VI) Facial (VII) Vestibulocochlear (VIII) Glossopharyngeal (IX) Vagus (X) Accessory (XI) Hypoglossal (XII) 42 Recite cranial nerves Mnemonic used Name the cranial nerves in order Oh Once One Takes The Anatomy Final, Very Good Vacations Seem Heavenly. Practice 43 43 Cranial nerves, base of the brain Frontal lobe Cranial nerves: Olfactory bulb (from olfactory nerve, I) Olfactory tract Optic chiasm Temporal lobe Infundibulum Optic nerve (II) Oculomotor nerve (III) Trochlear nerve (IV) Trigeminal nerve (V) Pons Abducens nerve (VI) Facial nerve (VII) Medulla Vestibulocochlear nerve (VIII) Glossopharyngeal nerve (IX) Cerebellum Vagus nerve (X) Hypoglossal nerve (XII) Accessory nerve (XI) Spinal cord 44 Base of the brain; ID the indicated structures Frontal lobe Cranial nerves: Olfactory tract Optic chiasm Temporal lobe Infundibulum Cerebellum Spinal cord Practice 45 Study Table 16.1 (in the lab manual)– cranial nerves and their functions 46