AGRID
Automated Glucose Reading Insulin Dispenser
www.cs.odu.edu/~svijayak/MainPageCS410.html
Presented by T. Gatdula
Co-presenters
S. Vijayakumar
D. Yang
Problem Statement
Diabetics do not follow their prescribed
insulin regimen.
Agenda
Societal problem
Problem statement
Project goal
Component requirements
Benefits
Obstacles
Risks & Mitigators
Preliminary budget
Projected schedule
Management methods
Resource requirements
American Diabetes Statistics
16 million cases of diabetes
2,500 new cases daily
7th leading cause of death
193,140 deaths in 1996
$44 billion in direct medical costs
*Statistics from ADA & NIDDK
Diabetes Management Survey
2/3 find regimen difficult to manage
41% “unsuccessful” at management
3 in 5 do not monitor as prescribed
17% do not maintain insulin regimen
1 in 5 find regimen restricting
*Survey by Eli Lilly company
Survey- Diabetics
Diabetics Vs. Non Diabetics
Diabetic Types
18%
44%
Diabetics
Type 1
Non Diabetics
56%
Type 2
82%
Type 1 Classification
Type 2 Classification
7%
12%
29%
15 Years or less
7%
6%
16-25Years
26-35 Years
26-35 Years
29%
36-45 Years
46-55 Years
46-55 Years
41%
14%
15 Years or less
16-25Years
36-45 Years
43%
12%
Survey- Monitoring
Blood Monitoring - Type1 & Type 2
4%
None
19%
42%
Once
Twice
35%
More than three
times
Problem Statement
Diabetics do not follow their prescribed
insulin regimen.
Project Goal
Given a simplified insulin protocol,
insulin-dependent diabetics will be more
likely to maintain their prescribed
insulin regimen.
Existing Monitoring Devices
Product Cost
Accuracy Issues
Accessories
Glucose
Monitor
$890/
annually
98-99%
Invasive,
Calluses
Strips,
Lancets
Glucose
Watch
$260
100%
Itchiness in
area
Batteries
Existing Dispensing Devices
Product
Cost
Insulin Pen $35
Syringe
Accuracy Issues
Accessories
99%
Intrusive,
Precision
Intrusive,
Precision
Needles
Needles,
Tubing
N/A
$23/100 100%
Disposal
System
Insulin
$4,000
Pump
Medication Varies
98.6%
Varies
Intrusive,
Complex
Regimented
Insulin
Patch
Not
Released
Final Testing N/A
Phase
~$3.20
Component Requirements
Blinker
Enter
100
1 2 3 4 5
6 7 8 9 0
Input
Ultra Sound
AGRID
Patch
Functional Diagram
User Info
Monitor
Low
Within
Range
Computational
Device
Warning
Ultra Sound
High
Patch
Warning
What AGRID Will Do
Glucose monitoring
Virtually non-invasive
Continuous
Insulin dispensing
Non-invasive
Continuous
What AGRID Will Not Do
Not a cure for diabetes
Not for those with minimal diabetes
Project Objectives
Research
Budget/cost projection
SBIR grant proposal
Acquisition of materials
Building of prototype
Validate product
AGRID Company Structure
Obstacles
Government approval
Side effects
Societal reluctance
Benefits
All-in-one
Convenient
Non-invasive
Unobtrusive
Peace of mind
Risks and Mitigators
Diabetes cured
Simpler regimentation
becomes available
Unable to acquire government
approval
Unit not covered by insurance
Very far into the future
Our solution is simple
Unable to attain user-rights
Find alternative devices
Alter product to meet
requirements
Reduce sales
Budget- Initial Development
Licensing
Costs
Software
Development
Development
Costs
Glucowatch
Insulin Patches
20,000
80,000
Ultrasound Device
50,000
30,000
$180,000
Testing
$200,000
TOTAL
$380,000
Budget- Production
Unit
AGRID
Costs
500
@ 200 units
$100,000
Operation
Testing
2,000
Cost
Maintenance
Computational
Device
5,000
Research &
Development
10,000
$17,000
TOTAL
$117,000
Profit Projections
AGRID
500
Retail
550
50
@100,000 units
$5,000,000
Insulin Patch
Retail
3
3.10
.10
@365 annual
@ 100,000 units
$3,650,000
TOTAL
$8,650,000
Schedule
Concept development- 3 months
Prototype design- 5 months
Pre-production design- 6 months
Production- 36 months
3 months
Concept
Development
5 months
6 months
Prototype Pre-Production
Design
Design
36 months
Production
Conclusion
Societal need
Financially feasible
Marketable
Within time constraints
Greater quality of life
Research Sites
www.diabetes123.com
www.childrenwithdiabetes.com
www.nih.gov
www.dcct.com
www.glucowatch.com
www.sontra.com
www.niddk.nih.gov