CURRICULUM VITAE
Name:
Robert Stanley Parker
Title:
Associate Professor
Department Affiliations:
Division of Nutritional Sciences and
Department of Food Science (Joint appointment)
Business Address:
226 Savage Hall
Division of Nutritional Sciences Cornell University
Ithaca, New York 14853
tel: (607) 255-2661
fax: (607)255-1033
Email: rsp3@cornell.edu
Home Address:
44 Catherine Drive
Dryden, New York 13053
Birth Date:
May 21, 1952
Nationality:
United States Citizen
INSTITUTION
DEGREE
MAJOR
DATE
Department of Food Science
Oregon State University
Corvallis, Oregon
Ph.D.
Food Science
1980
Department of Food Science
Oregon State University
Corvallis, Oregon
M.S.
Food Science
1978
Duke University
Durham, North Carolina
B.S.
Zoology & Botany
1974
PROFESSIONAL SOCIETY MEMBERSHIPS
American Society for Nutrition
Institute of Food Technologists
International Carotenoid Society
PROFESSIONAL EXPERIENCE
1988 -present:
Associate Professor, Division of Nutritional Sciences, Cornell University; Joint appointment,
Department of Food Science. Responsibilities: Research and teaching. My research program has
focused on the metabolism and bioavailability of vitamin A/-carotene and vitamin E, with current
focus on the latter. We are studying fundamental aspects of the metabolism and regulation of
metabolism of vitamin E in humans, and in the assessment of factors (environmental or dietary) which
may impact the bioavailability of this vitamin. Our research in vitamin E metabolism has involved a
combination of human studies (some involving stable tracer methodologies), genetically modified mice,
novel cell culture models, and in vitro assay systems aimed at elucidating mechanisms of regulation of
vitamin E status and metabolism. Through collaboration we are investigating the function of a vitamin
E binding protein in the brain and bioavailability of vitamin E in commercially important avian species.
The research has been funded by NIH, USDA, and corporate sources.
2012-present: Director of Undergraduate Studies, Division of Nutritional Sciences, Cornell University
2001 – 2008: Associate Director for Academic Affairs, Division of Nutritional Sciences, Cornell
University, Ithaca, NY.
1996-1997: Visiting scholar, Staecie Institute of Molecular Sciences, National Research Council of
Canada, Ottawa (sabbatical leave)
1992 (Feb-March, Nov-Dec): Visiting Scholar, Inter-University Center for Food Science and Nutrition,
Institut Pertanian, Bogor, Indonesia.
1980 -1988:
Assistant Professor, Division of Nutritional Sciences, and Department of Food Science (Joint
appointment), Cornell University, Ithaca, New York. Responsibilities: Research and teaching.
July 1978 -October 1980:
Graduate Research Assistant, Department of Food Science and Technology, Oregon State University,
Corvallis, Oregon. Doctoral research activity in the laboratory of Prof. D.P. Selivonchick in
uptake and metabolism of phospholipid vesicles by juvenile oysters. Other research activity in
xenobiotic metabolism in fish and techniques of preparing and using isolated trout hepatocytes for this
purpose.
September 1975 -June 1978:
Graduate Research Assistant, Department of Food Science and Technology, Oregon State University,
Corvallis, Oregon. Master's research in the laboratory of Prof. R.O. Sinnhuber concerning
metabolism of the essential fatty acid [1-14C] linolenic acid in coho salmon. Other research in various
aspects of toxicology, including toxic effects of rapeseed oil in trout rations and metabolism of
cyclopropenoid fatty acids.
1974 -1975:
On-site research coordinator in Tunis, Tunisia for an EPA PL-480 research project concerning
pollution-related eutrophication in the Lake of Tunis. Responsible for setting up a functional laboratory,
data gathering and interpretation, training of Tunisian technicians and university students, and
budgetary matters. (12-month appointment)
CITATION INDICES
249
JOURNAL PUBLICATIONS (chronological order)
1. Eisele, T.A., R.S. Parker, J.K. Yoss, J.E. Nixon, N.E. Pawlowski and R.O. Sinnhuber. 1979.
Incorporation of label from 9,10-methylene-14C sterculic acid in rainbow trout, Salmo gairdneri.
Lipids 14(6):523-528.
2. Parker, R.S., D.P. Selivonchick and R.O. Sinnhuber. 1980. Turnover of label from [1-14C] linolenic
acid in phospholipids of coho salmon, Oncorhynchus kisutch. Lipids 15(2):80-85.
3. Parker, R.S., M.T. Morrissey, P. Moldeus and D.P. Selivonchick. 1981. The use of isolated
hepatocytes from rainbow trout (Salmo gairdneri) in the metabolism of acetaminophen. Compo
Biochem. Physiol. 70B:631-633.
4. Parker, R.S. 1982. Vegetable oils and margarines as sources of polyunsaturated fatty acids.
Professional Perspectives, Division of Nutritional Sciences, Cornell University (May 1982).
5. Parker, R.S. 1985. Dietary carotenoids and cancer. Professional Perspectives, Division of Nutritional
Sciences, Cornell University (Jan-Feb).
6. Bauman, P.A., J.H. Hotchkiss and R.S. Parker. 1985. Comparative metabolism of N-nitrosodi- npropylamine and N-nitrosodiallylamine by isolated rat hepatocytes. Cancer Lett. 28:229-236.
7. Baldwin, S. and R.S. Parker. 1985. Alteration of rat hepatic lipid composition by dietary fat level and
aflatoxin B1. Food Chern. Toxicol. 23(12):1049-1055.
8. Taylor Mayne, S. and R.S. Parker. 1986. Subcellular distribution of dietary beta-carotene in chick
liver. Lipids 21(2):164-169.
9. Parker, R.S. and D.P. Selivonchick. 1986. Uptake and metabolism of lipid vesicles from
seawater by juvenile Pacific oysters, Crassostrea gigas. Aquaculture 53:215-228. .
10. Baldwin, S. and R.S. Parker. 1986. Effects of dietary fat and selenium on the development of
preneoplastic lesions in rat liver. Nutr. Cancer 8(4):273-282.
11. Baldwin, S. and R.S. Parker. 1987. Influence of dietary fat and selenium in initiation and
promotion of aflatoxin B I-induced preneoplastic foci in rat liver. Carcinogenesis 8(1): 101-107.
12. Whitacre, M.E., G.F. Combs, Jr., S.B. Combs and R.S. Parker. 1987. Influence of dietary
vitamin E on nutritional pancreatic atrophy in selenium-deficient chicks. J. Nutr. 117(3):460-467.
13. Parker, R.S. 1988. Carotenoid and tocopherol composition of human adipose tissue. Am. J. Clin.
Nutr. 47:33-36.
14. Goodrich, R.M., R.S. Parker, D.J. Lisk, and G.S. Stoewsand. 1988. Glucosinolate, carotene and
cadmium content of Brassica oleracea grown on municipal sewage sludge. Food Chem. 27:141-150.
15. Taylor Mayne, S. and R.S. Parker. 1988. Cis-canthaxanthin and other carotenoid-like compounds in
canthaxanthin preparations. J. Agric. Food Chem. 36(3):478-482.
16. Taylor Mayne, S. and R.S. Parker. 1988. HPLC analysis of vitamin E by conversion to alphatocopheryl acetate in samples containing canthaxanthin or other co-eluting compounds. J. Agric. Food
Chem. 36(3):483-485.
17. Parker, R.S. 1989. Carotenoids in human blood and tissues. J. Nutr. 119:101-104.
18. Mayne, S. T. and R.S. Parker. 1989. Antioxidant activity of dietary canthaxanthin. Nutr. and Cancer
12(3):225-236.
19. Parker, R.S. 1989. Dietary and biochemical aspects of vitamin E. Adv. Food Nutr. Res. 33:157232.
20. Fan, W., R. Parker, B. Parpia, Q. Yinsheng, P. Cassano, M. Crawford, J. Ley ton, J. Tian, L.
Jungyao, C. Junshi, and T. Campbell. 1990. Erythrocyte fatty acids, plasma lipids and cardiovascular
disease in rural China. Am. J. Clin. Nutr. 52:1027-1036.
21. Potischman, N., C.E. McCulloch, T. Byers, T. Nemoto, N. Stubbe, R.Milch, R. Parker, K.M.
Rasmussen, M. Root, S. Graham, and T. Campbell. 1990. Breast cancer and dietary and plasma
concentrations of carotenoids and vitamin A. Am. J. Clin. Nutr.52:909-915.
22. Fuller, C.J., H. Faulkner, A. Bendich, R.S. Parker, and D.A. Roe. 1992. Effect of B-carotene
supplementation on photosuppression of delayed-type hypersensitivity in normal young men. Am. J.
Clin. Nutr. 56:684-690.
23. Parker, R.S. 1993. Analysis of carotenoids in human plasma and tissues. Methods in Enzymology
214:87-93.
24. Parker, R.S., J.E. Swanson, B. Marmor, K.J. Goodman, A.B. Spielman, J.T. Brenna, S.M. Viereck,
and W.K. Canfield. 1993. Study of -carotene metabolism in humans using 13C--carotene and high
precision isotope ratio mass spectrometry. Annals of the New York Academy of Sciences 691:86-95.
25. Rock, C.L., J.L. Rodriguez, R. Khilnani, D.A. Lown, and R.S. Parker.1993. Carotenoids and
antioxidant nutrients following burn injury. Annals of the New York Academy of Sciences 691:274278.
26. Fuller, C.J., R.S. Parker, A. Spielman, and D.A. Roe. 1993. Carotenoid-depletion diet for use in
long-term studies. J. Am. Diet. Assoc. 93(7):812-814.
27. Parker, R.S. 1994. Physiological and biochemical determinants of the bioavailability of tocopherols
and carotenoids. Proceedings of the USP Open Conference on Nutritional Supplements Standards and
Information Issues, May 1994. U.S. Pharmacopeial Convention, Inc., Rockville, MD.
28. Parker, R.S. 1996. Absorption, metabolism and transport of carotenoids. FASEB Journal 10:542551 (Invited review).
29. Swanson, J.E., Goodman, K.J., and Parker, R.S. 1996. Experimental approaches to the study of carotene metabolism: potential of a 13c tracer approach to modeling B-carotene kinetics in humans.
Adv. Food Nutr. Res. 40:55-79.
30. You, C.-S., Parker, R.S., Goodman, K.J., Swanson, J.E. and Corso, T.N. 1996. Evidence of cis trans isomerization of 9-cis--carotene during absorption in humans. Am. J. Clin. Nutr. 64:177-83.
31. Hadju, V., L. Stephenson, K. Abadi, H. Mohammed, D. Bowman and R. Parker. 1996.
Improvements in appetite and growth in helminth-infected schoolboys three and seven weeks after a
single dose of pyrantelpamoate. Parasitology, 113:497-504.
32. Parker, R.S. 1996. B-Carotene metabolism and cancer. Proceedings of the International
Conference on Food Factors: Chemistry and Cancer Prevention, Hamamatsu, Japan.
33. Zhu, Y., Hsieh, W-C., Herraiz, L., Parker, R.S., Haas, J.D., Swanson, J.E., and Roe, D.A.
1996. Evidence of a role for fat-free body mass in modulation of plasma carotenoid concentrations in
older men: studies with hydrodensitometry. J. Nutr.127: 321-26.
34. Parker, R. S., Brenna, J. T., Swanson, J. E., Goodman, K. J., and Marmor, B. (1997) Assessing
metabolism of ß-[13C]carotene using high-precision isotope ratio mass spectrometry. Methods in
Enzymology 282:130–140.
35. He, Y., Root, M.M., Parker, R.S., and Campbell, T.C. 1997. Effects of carotenoid-rich food
extraction on the development of preneoplastic lesions in rat liver and on in vivo and in vitro
antioxidant status. Nutrition and Cancer 27(3), 238-244.
36. Rock, C.L., Dechert, R.E., Khilnani, R., Parker, R.S., and Rodriguez, J.L. 1997. Carotenoids and
antioxidant vitamins in patients after burn injury. J. Burn Care Rehabil. 18:269-78.
37. Parker, R.S. 1997. Bioavailability of carotenoids. In: Recommendations on the Assessment of
the Bio-availability of Micronutrients, (M. Jackson, ed). Eur. J. Clin. Nutr. 51 (Suppl): 86-90.
38. Herraiz, L.A., Hsieh, W.-C., Parker, R.S., Swanson, J.E., Bendich, A., and Roe, D.A. 1998. Effect
of UV exposure and ß-carotene supplementation on delayed-type hypersensitivity response in healthy
older men. J. Amer. Coll. Nutr. 17:617-624.
39. Hadju, V., Stephenson, L.S., Mohammed, H.O., Bowman, D.D. and Parker, R.S. 1998.
Improvements of growth, appetite, and physical activity in helminth-infected schoolboys 6 months after
single dose of albenazole. Aisa Pac. J. Clin. Nutr. 7(2):170-176.
40. Root, M.M., Hu, J., Stephenson, L.S., Parker, R.S. and Campbell, T.C. 1999. Iron status of
middle-aged women in five counties of rural China. Eur. J. Clin. Nutr. 53:199-205.
41. Parker, R.S., Swanson, J.E., You, C.-S., Edwards, A.J., and Huang, T. 1999. Bioavailability of
carotenoids in humans. Proceedings of the Nutrition Society, 58:155-162.
42. Swanson, J.E., Ben, R.N., Burton, G.W. and Parker, R.S. 1999. Urinary excretion of 2,7,8trimethyl-2-(-carboxyethyl)-6-hydroxychroman is a major route of elimination of -tocopherol in
humans. J. Lipid Res. 40:665-671.
43. Parker, R.S. 2000. Methodological considerations in determining vitamin A and carotenoid
bioactivity in humans. Food Nutr. Bull. 21(2), 124-129.
44. Parker, R.S. and Swanson, J.E. 2000. A novel 5’-carboxychroman metabolite or -tocopherol
secreted by HepG2 cells and excreted in human urine. (Biochem. Biophys. Res. Commun. 269, 580583.
45. Parker, R.S., Sontag, T.J., and Swanson, J.E. 2000. Cytochrome P4503A-dependent metabolism of
tocopherols and inhibition by sesamin. Biochem. Biophys. Res. Commun. 277, 531-534.
46. Edwards, A.J., Parker, R.S., You, C.-S., Swanson, J.E. 2001. A novel extrinsic reference method
for determining the vitamin A value of plant foods. Am. J. Clin. Nutr. 74(3), 348-355.
47. McGraw, K.J., Hill, G.E., Stradi, R., and Parker, R.S. 2001. The influence of carotenoid
acquisition and utilization on the maintenance of species-typical plumage pigmentation in male
American goldfinches (Carduelis tristis) and northern cardinals (Cardinalis cardinalis). Physiol.
Biochem. Zool. 74(6):843-852.
48. Edwards, A.J., Nguyen, C.H., You, C.-S., Swanson, J.E., Emenhiser, C., and Parker, R.S. 2002.
Alpha- and beta-carotene from a commercial carrot puree are more bioavailable to humans than from
boiled-mashed carrots, as determined using an extrinsic stable isotope reference method. J. Nutr. 132,
159-167.
49. McGraw, K.J., Hill, G.E., Stradi, R., and Parker, R.S. 2002. The effect of dietary carotenoid access
on sexual dichromatism and plumage pigment composition in the American goldfinch. Comp.
Biochem. Physiol. B 131: 261-269.
50. McGraw, K.J., Adkins-Regan, E., and Parker, R.S. 2002. Anhydrolutein in the zebra finch: a new,
metabolically derived carotenoid in birds. Comp. Biochem. Physiol. B, 132, 811-818.
51. You, C.-S., Parker, R.S. and Swanson, J.E. 2002. Bioavailability and vitamin A value of carotenes
from red palm oil assessed by an extrinsic isotope reference method. Asia Pacific J. Clin. Nutr.
11(Suppl), S438-S442.
52. Sontag, T.J. and Parker, R.S. 2002. Cytochrome P450 -hydroxylase pathway of tocopherol
catabolism: Novel mechanism of regulation of vitamin E status. J. Biol. Chem. 277(28), 25290-25296.
53. Parker, R.S. 2002. Role of cytochrome P450-mediated metabolism in the bioavailability of
vitamin E. Free Rad Res 36 (Suppl 1), 5-7.
54. Frank, J., Lundh, T., Parker, R.S., Swanson, J.E., Vessby, B and Kamal-Eldin, A. 2003. Dietary
(+)-catechin and BHT markedly increase -tocopherol concentrations in rats by a tocopherol-hydroxylase-independent mechanism. J. Nutr. 133 (10), 3195-3199.
55. McGraw, K.J., Beebee, M.D., Hill, G.E. and Parker R.S. 2003. Lutein-based plumage coloration in
songbirds is a consequence of selective pigment incorporation into feathers. Comp Biochem Physiol B
Biochem Mol Biol. 135(4), 689-696.
56. Ross, A.B., Chen, Y., Frank, J., Swanson, J.E., Parker, R.S., Kozubek, A., Lundh, T., Vessby, B.,
Aman, P. & Kamal-Eldin, A. 2004. Cereal alkylresorcinols elevate -tocopherol levels in male
Sprague-Dawley rats and inhibit tocopherol metabolism in vitro. J. Nutr. 134(3), 506-510.
57. Soo C. C-Y, Haqqani, A.S., Hidiraglou, N., Swanson, J.E., Parker, R.S. & Birnboim, H.C. 2004.
Dose-dependent effect of dietary alpha and gamma tocopherol on genetic instability in mutatect mouse
tumors. J Natl Cancer Inst. 96(10): 796-800.
58. Parker, R.S., Sontag, T.J., Swanson, J.E. and McCormick, C.C. 2004. Discovery, characterization
and significance of the cytochrome P450 -hydroxylase pathway of vitamin E catabolism. In: Vitamin
E and Health, Vol. 1031, F. Kelly, M. Meydani, and L. Packer, eds. Ann. N. Y. Acad. Sci.
59. Parker, R.S., Sontag, T.J., Swanson, J.E. and McCormick, C.C. 2004. Discovery, characterization
and significance of the cytochrome P450 -hydroxylase pathway of vitamin E catabolism. In: Vitamin
E and Health, Vol. 1031, F. Kelly, M. Meydani, and L. Packer, eds. Annals Online,
www.annalsnyas.org
60. McCormick, C.C and Parker, R.S. 2004. The cytotoxicity of vitamin E is both vitamer- and cellspecific and involves a selectable trait. J. Nutr 134(12), 3335-3342.
61. Sontag TJ and Parker RS. 2004. Vitamin E exhibits concentration- and vitamer-dependent
impairment of microsomal enzyme activities. Ann N Y Acad Sci. 1031, 376-377.
62. You CS, Sontag TJ, Swanson JE, Parker RS. 2005. Long-chain carboxychromanols are the major
metabolites of tocopherols and tocotrienols in A549 lung epithelial cells but not HepG2 cells. J
Nutr.135(2):227-232.
63. Parker RS and McCormick CC. 2005. Selective accumulation of alpha-tocopherol in Drosophila
melanogaster is associated with tocopherol--hydroxylase activity but not with tocopherol transfer
protein. Biochem. Biophys. Res. Comm. 338:1537-1541.
64. Frank J, Budek A, Lundh T, Parker RS, Swanson JE, Lourenco CF, Gago B, Jaranjinha J, Vessby B
and Kamal-Eldin A. 2006. Dietary flavonoids with a catechol structure increase -tocopherol in rats
and protect the vitamin from oxidation in vitro. J. Lipid Res 47(12), 2718-2725.
65. Bezzerides A, McGraw K, Parker RS, Husseini J. 2007. Elytra color as a signal of chemical
defense in the Asian Ladybird beetle axyridis. Behav Ecol Sociobio 61:1401-1408.
66. Sontag, TJ and Parker, RS. 2007. Influence of major structural features of tocopherols and
tocotrienols on their omega-oxidation by tocopherol-omega-hydroxylase. J Lipid Res. 48(5), 10901098.
67. Ohnmacht S, Nava P, West R, Parker R, Atkinson J. 2008. Inhibition of oxidative metabolism of tocopherols
with omega-N-heterocyclic derivatives of vitamin E. Bioorganic & Medicinal Chemistry 16(16), 7631-7638.
68. Williams IO, Parker RS, Swanson J. 2010. Vitamin A content of southeastern Nigerian vegetable
dishes, their consumption pattern and contribution to vitamin A requirement of pregnant women in
Calabar Urban, Nigeria. Pakistan J Nutrition 8:1000-1004.
69. Gong Y, Parker RS, Richards MP. 2010. Factors affecting lipid oxidation in breast and thigh
muscle from chicken, turkey and duck. J Food Biochem 34:869-885.
70. Morley S, Danielpour D, Parker R, Atkinson J and Manor D. 2010. The tocopherol transfer protein
sensitizes prostate cancer cells to vitamin E. J Biol Chem 285:35578-35589.
71. Bardowell, SA, Stec, D and Parker RS. 2010. Common variants in cytochrome P450 4F2 exhibit
altered vitamin E-omega-hydroxylase activity. J Nutrition 140:1901-1906
72. Ulatowski L, Parker R, Davidson C, Yanjanin N, Kelley TJ, Corey D, Atkinson J, Porter F, Arai H,
Walkley SU, Manor D. 2011. Altered vitamin E status in Niemann-Pick type C disease. J Lipid Res
52:1400-1410.
73. Bardowell SA, Duan F, Manor D, Swanson JE, Parker RS. 2012. Disruption of mouse cytochrome
P450 4f14 (CYP4f14 gene) causes severe perturbations in vitamin E metabolism. J Biol Chem
287:26077-26086.
74. Bardowell SA, Ding X, Parker RS. 2012. Disruption of P450-mediated vitamin E hydroxylase
activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E
metabolism. J Lipid Research 12: 2667-2676.
75. Nicod N, Parker RS. 2013. Vitamin E secretion by Caco-2 monolayers to APOA1, but not to
HDL, is vitamer selective. J Nutrition 143(10):1565-1572.
76. Ulatowski L., Parker R., Warrier G, Sultana R, Butterfield DA, Manor D. 2013. Vitamin E is
essential for Purkinje neuron integrity. Neuroscience 260: 120-129.
77. Nicod N, Chiva-Blanch G, Giordano E, Dávalos A, Parker RS, Visioli F. 2014. Green tea, cocoa,
and red wine polyphenols moderately modulate intestinal inflammation and do not increase highdensity lipoprotein (HDL) production. J Agric Food Chem. 62(10):2228-32.
78. Frankel PH, Parker RS, Madsen FC, Whanger PD. 2014. Baseline selenium and prostate cancer
risk: comments and open questions. J Natl Cancer Inst. Mar;106(3). [Invited Commentary]
79. Nicod N, Parker RS, Giordano E, Maestro V, Davalos A, Visioli F. 2014. Isomer-specific effects of
conjugated linoleic acid on HDL functionality associated with reverse cholesterol transport. J Nutr
Biochem. Nov 12. [Epub ahead of print]
80. Orcheski B, Parker R, Brown S. Pale green lethal disorder in apple (Malus) is caused by a mutation
in the PHYLLO gene which is essential for phylloquinone (vitamin K1) biosynthesis. Tree Genetics &
Genomics 11: 131 (Published online: 20 November 2015)
Papers in Press or Review:
Perez DM, Richards MP, Parker RS, Berres ME, Wright AT, Sifri M, Sadler NC, Tatiyaborworntham
N, Li N. 2016. Role of cytochrome P450 hydroxylase in the decreased accumulation of vitamin E in
muscle from turkeys compared to that from chickens. J Ag Food Chem (In Press)
BOOK CHAPTERS
Hotchkiss, J.H. and R.S. Parker. “Toxic compounds produced during cooking and meat processing.”
In: Meat and Health, A.M. Pearson and T.R. Dutson, eds., 1990. Elsevier, Ltd., Essex, UK.
Swanson, J.E., and Parker, R.S. “Biological effects of carotenoids in humans”. In:
Handbook of Antioxidants, L. Packer and E. Cadenas, eds. 1996. Marcel Dekker, Inc., New York.
Parker, Robert. “Phytochemicals: Carotenoids”. In: Wiley Encyclopedia of Food Science, 2nd edition,
C. Francis, Ed. 2000. John Wiley & Sons, New York, NY.
Parker RS. “Vitamin E”. In: Biochemical, Physiological, Molecular Aspects of Human Nutrition, M.
Stipanuk, Ed. 2006. Saunders Elsevier, St. Louis, MO.
Atkinson J, Manor D, Parker R. "Vitamin E". In: Encyclopedia of Biological Chemistry. W. Lennarz,
M. Lane, P. Modrich, J. Dixon, E. Carafoli, J. Exton, D. Cleveland, Eds. 2010. Elsevier, St. Louis, MO.
Parker RS. “Vitamin E”. In: Biochemical, Physiological, Molecular Aspects of Human Nutrition, M.
Stipanuk, Ed. 2012. Saunders Elsevier, St. Louis, MO.
ABSTRACTS AND POSTER PRESENTATIONS
Parker, R.S., D.P. Selivonchick, M.T. Morrissey and P. Moldeus. 1980. Acetaminophen
metabolism in isolated hepatocytes from rainbow trout (Salmo gairdneri). Fed. Proc. 39:552.
Cho, S.H., R.S. Parker and V. Utermohlen. 1982. Platelet arachidonic acid metabolism in
multiple sclerosis, systemic lupus erythematosus and healthy control subjects. Fed. Proc. 41:356.
Boyd, J., N. Misslbeck, R.S. Parker and T.C. Campbell. 1982. Sucrose enhanced emergence of
aflatoxin Bl (AFBl)-induced GGT-positive rat hepatic cell foci. Fed. Proc. 41:356.
Baldwin, S.V. and R.S. Parker. 1983. Influence of dietary lipids and selenium on emergence of
preneoplastic hepatic foci induced by aflatoxin Bl in rats. Fed. Proc. 42(5):1312.
Parker, R.S. and D.P. Selivonchick. 1983. Uptake and metabolism of lipid vesicles from
seawater by juvenile Pacific oysters, Crassostrea gigas. J. Am. Oil Chem. Soc. 60(4):728. .
Whitacre, M.E., G.F. Combs, Jr. and R.S. Parker. 1983. Peroxidative damage in nutritional pancreatic
atrophy due to selenium deficiency in the chick. Fed. Proc. 42(4):928.
Parker, R.S. 1985. Influence of dietary beta-carotene on the stability of mitochondrial retinol, alphatocopherol, and fatty acids during NADPH-induced peroxidation. Fed. Proc. 44(3):543.
Taylor, S. and R.S. Parker. 1985. Hepatic subcellular distribution of beta-carotene, retinol and alphatocopherol in rat and chick. Fed. Proc. 44(3):771.
Colford, J. and R.S. Parker. 1986. Effect of beta-carotene, vitamin A, and selenium on formation of
preneoplastic lesions in rat liver. Fed. Proc. 45(4):1089.
Stoewsand, G.S., C.E. Godlewski, J.N. Boyd and R.S. Parker. 1986. Carcinogenesis inhibitors in
brussels sprouts. Fed. Proc. 45(4):970.
Baldwin, S. and R.S. Parker. 1986. The influence of dietary fat and selenium fed during. initiation or
promotion on the development of preneoplastic lesions in rat liver. Fed. Proc. 45(4):1088.
Mayne, S. T. and R.S. Parker. 1987. Dietary canthaxanthin as a protective agent against lipid
peroxidation in biomembranes. Fed. Proc. 46(4):1189.
Baldwin, S. and R.S. Parker. 1987. Influence of dietary fat and selenium on glutathione-Stransferases and DNA binding and subcellular disposition of aflatoxin B1 in rat liver. Fed. Proc.
46(3):749.
Taylor Mayne, S. and R.S. Parker. 1987. Cis-canthaxanthin and other carotenoid-like
compounds in canthaxanthin preparations. 8th International Symposium on Carotenoids, Boston, MA,
July 27-31, 1987.
Parker, R.S., J. Chen, T.C. Campbell, J. Boreham, G. Wang, L. Houghton, and L. Youngman. 1988.
Geographical variation in erythrocyte fatty acid composition in the PRC and its relationship to diet and
chronic disease. The FASEB Journal2(5):A1080.
Colford, J., A. Smith, and R. Parker. 1990. Dietary selenite enhances AFB1 detoxification and reduces
AF-DNA binding in isolated rat hepatocytes. The FASEB Journal4(4):A1175.
Parker, R.S., S.M. Viereck, A.B. Spielman, J.T. Brenna, and K.J. Goodman. 1992. Metabolism and
biokinetics of 13C--carotene in humans following a small oral dose. FASEB Journal6(5):A1645.
Swanson, JE and Parker, R.S. 1993. Effect of iron deficiency on liver vitamin A and -carotene stores
in rats fed -carotene as sole source of vitamin A. Experimental Biology 93, New Orleans, LA.
You, C-S., R.S. Parker, K. Goodman, J.T. Brenna, and W.K. Canfield. "Metabolism of 13C- 9cis-carotene in humans". FASEB Journal, 1994, 8, A422.
Marmor, B., R.S. Parker, J.E. Swanson, C-S. You, Y. Wang, K. Goodman, J.T. Brenna, and
W.K. Canfield. "Metabolism of 13C -carotene in a human subject as a function of carrier lipid".
FASEB Journal, 1994, 8, A192.
Herraiz, L., A. Rahman, R.S. Parker, and D.A. Roe. "The role of -carotene supplementation in
prevention of photos up pression of cellular immunity in elderly men". FASEB Journal, 1994, 8, A423.
You, C.-S., R.S. Parker, K.J.Goodman, J.T. Brenna and W.K. Canfield. 1995. Evidence of cis- trans
isomerization of 9-cis--carotene in humans. FASEB J., 9(3), A442.
Hadju, V., L. Stephenson, K. Abadi, H. Mohammed, D. Bowman and R. Parker. 1996. Improvements
in growth and physical activity in helminth-infected schoolboys following a single dose of albendazole.
FASEB J. 10(3), A246.
Swanson, J.E, Ben, R. Burton, G.W. and Parker, R.S. 1998. Urinary excretion of 2,7,8-trimethyl-2-(ßcarboxyethyl)-6-hydroxychroman (-CEHC) represents a major pathway of elimination of -tocopherol
in humans. FASEB J.
McCormick, C.C. and Parker, R.S. 2001. Cytotoxicity of tocopherols: a cell-specific and selectable
mechanism involving cellular uptake. FASEB J. 15(3), 55 (LB298).
Sontag, T.J. and Parker, R.S. 2003. Comparative influence of specific structural features of
tocopherols and tocotrienols in their -oxidation by hepatocytes and microsomal membranes. FASEB
J. 17(4), A280.
Swanson, J, You, C-Y, and Parker, R. 2004. Tocopherol metabolism by Caco-2 cells and inhibition by
sesamin and the polyphenols genistein and resveratrol. FASEB J 18(4), A160.
You, C-Y, McCormick, C.C. and Parker, R.S. 2004. Metabolism and cytotoxicity of tocopherols and
tocochromanols in human type II (A549) pneumocytes. FASEB J 18(4), A159.
Nicod, NM and Parker, RS. 2007. Basolateral tocopherol secretion to apoA1, but not to HDL, is
vitamer selective in Caco-2 monolayers. FASEB J 21(5), A354.
ORAL PRESENTATIONS TO PROFESSIONAL ORGANIZATIONS
Invited Presentations
"Update on Essential Fatty Acids". Genesee Dietetic Association Annual Meeting, Rochester, NY,
September 1983. (Invited speaker)
"Cancer and cardiovascular disease vs. dietary polyunsaturated fatty acids: lack of a conflict".
Symposium on Dietetic and Pharmacologic Lipids, 189th Annual Meeting of the American Chemical
Society, Miami, FL, May 1985. (Invited speaker).
"Polyunsaturated fatty acids in cancer and cardiovascular disease". Annual Meeting of the Pennsylvania
Dietetics Association, Scranton, PA, April 1986. (Invited speaker)
"Carotenoids in tissues and membranes". Symposium on Vitamin A and Carotenoids, 190th Annual
Meeting of the American Chemical Society, New York, NY, April 1986. (Invited speaker).
"Carotenoids in human blood and tissues". Symposium on Biological Functions of Carotenoids.
Federation of American Societies of Experimental Biology, Las Vegas, NY, May 2, 1988. (Invited
speaker).
"Chemistry and functionality of antioxidants in foods". Annual meeting of the Biscuit and Cracker
Manufacturer's Association, Denver, CO, October 16, 1989. (Invited speaker).
"Carotenoids in human plasma and tissues". 1st Gordon Conference on Carotenoids, Oxnard, CA,
March 9-13, 1992. (Invited speaker).
"Novel method of studying -carotene metabolism in humans: Implications for potential
mechanisms of disease prevention". New York Academy of Medicine, New York, NY, April 15, 1992.
(Invited speaker).
"Novel stable isotope tracer method for studying -carotene and vitamin A metabolism in humans".
Bassett Hospital, Cooperstown, NY, May 29, 1992. (Invited speaker).
"Study of -carotene metabolism in humans using 13C--carotene and high precision isotope ratio
mass spectrometry". New York Academy of Sciences Symposium on Carotenoids in Human Health,
San Diego, CA, Feb. 6-9, 1993. (Invited speaker).
"Physiological and biochemical detenninants of the bioavailability of tocopherols and carotenoids".
U.S. Pharmacopeia Open Conference, Boston, MA. May 1994. (Invited)
"Application of high precision isotope ratio mass spectrometry to the study of-carotene metabolism in
humans". American College of Sports Medicine, June 1-4, 1994. (Invited)
"Metabolism of carotenoids and tocopherols: An update". 2nd International Conference on Antioxidant
Vitamins and B-Carotene, Berlin, Germany, October 10-12, 1994. (Invited)
"Use of 13C-labeled carotenoids in the study of their metabolism in humans". Gordon Conference on
Carotenoids, Ventura, CA, February 5-9, 1995 (Invited speaker).
"Carotenoids as Cancer Chemopreventive Agents", New York Hospital-Cornell Medical Center, April
20, 1995. (Invited speaker)
“-Carotene Metabolism and Cancer", International Conference on Food Factors", Hamamatsu, Japan,
Dec. 12, 1995. (Invited participant)
"Metabolism of 13C--Carotene in Humans: Studies with High Precision Isotope Ratio Mass
Spectrometry", 11th Internation Symposium on Carotenoids, Leiden, Netherlands, Aug 20-23,
1996. (Invited speaker)
"Bioavailability of Carotenoids", Workshop on the Assessment of the Bioavailability of
Micronutrients, Norwich, UK, Mar 25-26, 1996 (Invited speaker)
"Absorption and Metabolism of Carotenoids", 2nd Karlsruhe Nutrition Symposium, Karlsruhe,
Germany, Oct. 12-14, 1997. (Invited speaker)
“Vitamin E oxidation products generated in vivo.” FASEB Summer Research Conference on Molecular
and Biological Mechanisms of Antioxidant Action. Copper Mountain, CO. Aug 3, 1998. (Invited
speaker)
“Methodological considerations in determining vitamin A and carotenoid bioactivity in humans.”
Workshop on Dietary Approaches to Vitamin A Deficiency, Aug 27-28, 1999, Seoul, Korea. (Invited
speaker)
“Bioavailability and vitamin A value of carotenes from red palm oil assessed by an extrinsic isotope
reference method.” International Palm Oil Research Conference, Aug 20-23, 2001, Kuala Lumpur,
Malaysia (Invited speaker)
“Role of Cytochrome P450-Mediated Metabolism in the Bioavailability of Vitamin E”. 2002
EUROFEDA Conference, Cambridge, UK, Sept 25-28, 2002. (Invited speaker)
“Tocopherol--hydroxylase: A novel cytochrome P450-mediated pathway of regulation of vitamin E
status”. 14th Annual Conference on Vitamin E Research, Nagoya, Japan, Jan 23-24, 2003 (invited
speaker).
“Regulation of vitamin E status by vitamer-selective catabolism via the tocopherol--oxidation
pathway”. Tokyo University, Jan 25, 2003. (Invited lecture).
“Discovery and characterization of the cytochrome P450 omega-hydroxylase pathway of tocopherol
catabolism.” New York Academy of Sciences conference on Vitamin E and Health , USDA Human
Nutrition Research Center on Aging, Boston, MA. May 22-24, 2004. (Invited plenary lecture).
“Cytochrome P450s in vitamin E metabolism and status”. Wadsworth Research Center, Albany NY,
March 28, 2013. (Invited seminar)
“Metabolic and non-metabolic mechanisms of regulation of vitamin E status as revealed by cytochrome
P-450-modified mice”. Purdue University, Oct 24, 2014. (Invited seminar)
Other Presentations
"Metabolism of [1-14C] linolenic acid in coho salmon, Oncorhynchus kisutch". Annual meeting of the
American Oil Chemists' Society, San Francisco, CA, May 3, 1978.
"Metabolism of acetaminophen in isolated hepatocytes from rainbow trout (Salmo gairdneri) ".
Federation of American Societies for Experimental Biology (FASEB), Anaheim, CA, April 1980.
"MUFAs, PUFAs, and EFAs: Are More Polyunsaturates Better?" Cornell Biennial Nutrition Institute,
June 1982.
"Uptake and metabolism of lipid vesicles from seawater by juvenile Pacific oysters, Crassostrea gigas".
American Oil Chemists'Society Annual Meeting, Chicago, IL, May 1983.
"The basis for concern regarding synthetic food antioxidants". Cornell Biennial Nutrition Institute,
June 1984.
"Influence of dietary beta-carotene on the stability of mitochondrial retinol, alpha-tocopherol, and fatty
acids during N AD PH-induced peroxidation ". Federation of American Societies for Experimental
Biology, Anaheim, CA, April 1985.
"Vitamin A and carotenoids". New York State Nutrition Institute, Cornell University, Ithaca, NY, June
5-6, 1986.
"Cis-canthaxanthin and other carotenoid-like compounds in canthaxanthin preparations". Taylor
Mayne, S. and R.S. Parker. 8th International Symposium on Carotenoids, Boston, MA, July 2731,1987.
"Geographical variation in erythrocyte fatty acid composition in the PRC and its relationship to diet and
chronic disease". Minisymposium on Diet and Cancer, Federation of American Societies of
Experimental Biology, Las Vegas, NY, May 3,1988.
"Metabolism and biokinetics of 13C--carotene in humans following a small oral dose". FASEB,
Anaheim, CA, April 6-9, 1992.
"Antioxidant Vitamins: Identity, Mechanism and Effects", Capital District Nutritional Concerns
Conference, Saratoga, NY, March 20, 1995.
“New insights into the metabolic vitamin A value of plant foods: Application of a novel stable isotope
reference method to assess bioavailability of provitamin A carotenoids in humans.” 13th International
Carotenoid Symposium, Honolulu, HI, Jan 7-11, 2002.
"Vitamer-selective cytochrome P450 pathway of vitamin E metabolism". Field of Animal Science,
Cornell University, March 9, 2006.
PATENTS
“Inhibitors of oxidative metabolism of tocopherols and tocotrienols (vitamin E)”. With J. Atkinson,
Department of Chemistry, Brock University, St. Catherines, Ontario CA. 2007.
WORKSHOPS
Workshop on RDA's. New Brunswick, NJ, April 13, 1993. (Invited participant).
Marabou Nutrition Symposium on Vitamin A. Stockholm, Sweden, June 11-14, 1993. (Invited
discussant).
Workshop on the Bioavailability and Bioconversion of Carotenoids, ILSI, Washington, D.C. April 4-5,
1995, sponsored by the Micronutrient Initiative and Opportunities for Micronutrient Interventions,
USAID. (Invited participant)
Workshop on Recommendations on the Assessment of the Bio-availability of Micronutrients, ILSIEurope, Norwich, UK. March 25-26, 1996. (Invited presenter).
OUTREACH ARTICLES AND PRESENTATIONS
"Factors Affecting Microbial Lethality", Cornell Food Preservation Workshop, June 1982 "Pectins and
pectin gels", Cornell Food Preservation Workshop, June, 1981.
"Essential Fatty Acids", Cornell Nutrition Update Workshop, June 1983.
"Diet and cancer", television interview for: Facets: Excursions into Science, Channel 13, Ithaca,
NY, November 1985.
Polyunsaturated Fatty Acids (Workshop). New Directions in Nutrition ill, Nassau County Cooperative
Extension Nutrition Conference, Plainview, NY, October 1985.
"-Carotene, vitamin A and vitamin E", Fall meeting, New York State Two-Year College
Chemistry Teachers Association, Alfred State College, Alfred, NY, October 8, 1988.
"Antioxidants in Foods", radio interview, Cornell Media Services, June 1992.
"Choosing Foods High in Antioxidants", with Metta Winter, Cornell Consumer News Service, 1993.
Series of three articles for publication
"Toxicological and Nutritional Pespectives on Food Irradiation", public testimony presented before the
NY Senate Consumer Protection Committee, October 20, 1993.
"Health Aspects of B-Carotene and Carotenoids", In: From Carrots to -Carotene: Agriculture and
Health Implications of Increasing Plant Foods in the Diets of New Yorkers, Cornell University, June 6,
1994.
CURRENT TEACHING RESPONSIBILITIES
NS 3450 (also FDSC 2000). Introduction to Physicochemical and Biological Aspects of Foods.
Fall, annually. This course is a core requirement for students majoring in either Nutritional Sciences or
in Food Science. Enrollment approx. 160. (Note: I have taught a version of this course since 1980; it
was merged with FDSC 2000 in 2010.)
NS 6310 Micronutrients: Function, Homeostasis and Assessment (with 3 other faculty; Fall, annually,
2007- present)
NS 6320 Regulation of Macronutrient Metabolism (with 4 other faculty; Spring 2008 - present)
CURRENT ADMINISTRATIVE RESPONSIBILITIES
Director of Undergraduate Studies, Division of Nutritional Sciences (2012 to present)
(Past duties have included chairing the DNS Curriculum Committee from 1985 – 2012.)
EXTERNAL SCHOLARLY ACTIVITIES
Ad Hoc reviewer of manuscripts for:
Journal of Biological Chemistry
Journal of Nutrition
American Journal of Clinical Nutrition
European Journal of Clinical Nutrition
Journal of Lipid Research
Journal of Nutritional Biochemistry
Archives of Biochemistry and Biophysics Biochemistry
Lipids
Journal of Agricultural and Food Chemistry
Co-chair, Experimental Biology '95, Minisymposium on Recent Advances in Carotenoid Research
1995.
External reviewer, Program on Antioxidants in Foods, Ministry of Agriculture, Fisheries and Food, UK
1995.
International Vitamin A Consultive Group, Committee on Research Needs in Evaluating Carotenoid
Bioavailability, 1997-1998.
Chair, Experimental Biology 2000, Minisymposium on Carotenoids
NIH Ad Hoc Review Panel, "Small Grants in Digestive Diseases and Clinical Nutrition" March 2006.