Pages: 460-473 Blood supply of the brain The blood supply of the brain comes mainly from the great cerebral circle which lies ventral to hypothalamus. - - -This (formerly known as circle of Willis) circle is supplied from: - Paired internal carotid artery - Basilar artery - Direct continuation of ventral spinal artery (reinforced by anastomosis with vertebral artery). Venous drainage The cranial sinuses enclosed within Dura mater are divided into dorsal and ventral system (limited communication) The dorsal sinus collect blood from dorsal part of the brain it includes: Dorsal sagittal sinus (within falx cerebri) Transverse sinuses within tentorium erebelli Venous drainage - The ventral or basilar system drains: - The ventral part of the brain - Receives major flow from veins that enter the orbit after draining much of the face, including the nasal cavity. Cranial Nerves • Twelve pairs: – 2 attach to forebrain (Telen- & Diencephalon) – 10 attach to brainstem (Midbrain, Pons, Medulla oblongata) • Names relate to appearance or function The 12 Pairs of Cranial Nerves I - Olfactory Nerves - Sensory - sense of Smell [cribriform plate] (neuron cell bodies located within olfactory epithelium on the ethmoidal labyrinth. II = Optic N. — Vision [optic foramen] cell bodies are in the retina (actually the "nerve" is a CNS tract enveloped by meninges) III - Oculomotor Nerves [orbital fissure] -Mixed nerve (motor & sensory) - Primary motor: Innervates four of the extrinsic eye muscles (dorsal, medial, & ventral rectus; ventral oblique) (ciliary body {accommodation} & iris {constrict pupil} The 12 Pairs of Cranial Nerves IV - Trochlear Nerves [orbital fissure] -Mixed nerves, innervates an extrinsic eye muscle - Dorsal oblique m V - Trigeminal Nerves - Provides sensory innervation to the face and motor innervation to chewing muscles 1- Ophthalmic n.: orbit; cornea; eyelids; & skin medial to eye [orbital fissure] 2- Maxillary n.: both lids laterally; upper jaw, teeth, lips; nose & nasal cavity [round f. & alar canal] 3- Mandibular n.: lower jaw, teeth, tongue; temporal region skin; innervates muscles of mastication [oval foramen] VI -Abducens Nerve [orbital fissure] - Mixed nerve, Abducts the eyeball (Lateral rectus m. ), 3rd eyelid & retractor bulbi m. The 12 Pairs of Cranial Nerves VII = Facial N. [stylomastoid f.] (Mixed) -Facial expression (ears, eye lids, nose, & lips) -Nasal glands, lacrimal gland, the two ventral Salivary glands (sublingual & mandibular) -Taste buds of rostral two-thirds of tongue VIII - Vestibulocochlear Nerves [internal acoustic meatus] -Sensory nerve of hearing and equilibrium organ found within petrous part of temporal bone: The 12 Pairs of Cranial Nerves IX - Glossopharyngeal Nerves [jugular foramen] - Mixed nerves, innervates structures of the tongue and pharynx -Taste; Pharyngeal sensation; Saliva -taste buds at caudal 1/3rd of tongue -parotid & zygomatic salivary glands - Sensory receptors in pharynx, middle ear, and carotid sinus & carotid body The 12 Pairs of Cranial Nerves X = Vagus N. [jugular foramen] -mm. of larynx, pharynx & esophagus (voice; cough; swallow) -Thoracic & abdominal viscera (receptors in viscera and in the larynx, also pharynx -Taste in region of pharynx - Skin of external auditory meatus XI = Accessory N. [jugular foramen] — Neck mm. [cleidocervicalis; cleidomastoideus; omotransversarius; trapezius] The 12 Pairs of Cranial Nerves XII = Hypoglossal N. [hypoglossal foramen] — Tongue mm - styloglossus, hyoglossus, genioglossus & intrinsic musculature) - contributes to innervations of sternohyoid & sternothryroid mm.]