Concepts to Know for DNA/RNA Test Scientists Griffith’s experiment and the cause of the transformation Chargaff and the rule of base pairing Rosalind Franklin Watson and Crick DNA Structure and Replication Griffith’s experiment and the cause of the transformation Be able to identify the components, draw, label the structure of DNA (know where the bases, phosphates, sugars are located) Identify the specific components that make up a nucleotide of DNA Chargaff’s Rule in base pairing Identify the steps of DNA replication in the order that they occur and identify the end products of DNA replication Identify which part of DNA specifically codes for the proteins Be able to provide a complementary strand of DNA when given a template Protein Synthesis (transcription, translation) Identify the differences that exist between DNA and RNA Name and explain the role of the 3 different types of RNA Explain Transcription: identify the different types of RNA involved, location, purpose Explain Translation: identify the different types of RNA involved, location, purpose Define codon, transcription, translation Be able to label the different structures involved with transcription/translation (look back at the worksheets) Be able to use the genetic code to identify the amino acid sequence Be able to convert from DNA to mRNA to tRNA to Amino Acid Mutations Define mutation Identify the different types of mutations – identify key characteristics of each type Identify the difference between gene mutations and chromosome mutations When given DNA sequences and chromosomes, be able to identify the different types of mutations Gene Regulation Define an Operon Define HOX genes. In what type of developmental stage are they important? Identify the difference between gene mutations and chromosome mutations When given DNA sequences and chromosomes, be able to identify the different types of mutations