DNA Notes How was the DNA Model Formed? 1) In the 1950’s a biochemist named Erwin __________ found that the amount of adenine (A) in DNA always equaled thymine (T), as is the same for cytosine (C) and guanine (G). Soon after this discovery was known as __________________: _______ = _______ _______= _______ 2) Soon after a young chemist named ____________ ______________ created images of DNA using a technique known as ________________. Franklin used X rays to create images on film and found that the general shape of DNA is a ____________ ______________ 3) In 1953 _____________ _____________, an American biochemist, and ____________ _____________, an English physicist, worked together in Cambridge, England to develop a model for DNA. Watson and Crick were the first scientist to discover the __________________. *DNA stands for ___________________ ______. Shape of DNA: It is the blueprint of life. DNA has a very distinct shape. It is arranged in a form of a helix. A helix is a shape of a _____ ____. However, a DNA molecule is a _______ ______ What is DNA made up of? DNA is made up of subunits called _____________. Each nucleotide is composed of 3 parts: a. _____________________________ b. _____________________________ c. _____________________________ Nitrogen Bases: Adenine – Thymine Cytosine – Guanine *All living things have the Same 4 bases, but the order matters! Nucleotide: What does the letters in your DNA code for? Your DNA sequence is a message for your cells to make specific _________. It is essentially like a recipe so your cells know what ingredients to put into your proteins. The proteins that are made allow you to express the ______________________ ________________ A gene is a piece of DNA that codes for a particular protein. How DNA makes a copy of itself One of the unique characteristics of DNA is that it can _____ _______using one of the strands as a _____. DNA can replicate and match base pairs to make complementary strands EX: Strand 1: A T C C G T A G C Strand 2 ____________________ Strand 1: T T G A T C T C C Strand 2 ____________________ Changes in Genes - Sometimes mistakes happen when DNA is copied, similar to how we might make a typo. - ___________ - change in DNA sequence. Sometimes they are random, and sometimes they are caused by external factors called mutagens. - ___________ - cause mutations. Examples include x-rays, UV light, chemicals in cigarettes - Types of Mutations o Substitution – a base is ___________ in the sequence o Deletion – a base is _____________ from the sequence o Insertion – a base is _____________ to the sequence