Fig. 1 Demographic and Clinical Profile of Patients By Presence of a Break in MMT Factors Participants With a Break From Participants With No Break in MMT MMT Gender Female Male Age (median) Ethnicity Irish Non- Irish Marital Status Single Cohabiting Married Education Primary incomplete Primary complete Junior Certificate Leaving Certificate Third Level Housing Homeless Hostel Others home Rented Own Employment Employed Unemployed Age first opioid use Length in MMT Starting methadone dose 0-20 21-40 41-60 61-80 >80 Current methadone dose 0-20 21-40 41-60 61-80 >80 GP in the community Number of GP visits per year (mean) Significance test N= 87 (46%) (χ2 (1) = 0.005, p= 0.943) 29.9% 70.1% (χ2 (3) = 5.821, p= 0.121) 33 (sd=7.2) 97.7% 1.1% (χ2 (2) = 8.764, p= 0.12) 58.3% 34.5% 7.1% (χ2 (4) = 3.399, p= 0.493) 7.1% 32.9% 32.9% 14.1% 12.9% (χ2 (4) = 7.349, p= 0.119) 7.6% 30.4% 15.2% 20.3% 26.6% (χ2 (1) = 0.067, p= 0.796) 5.7% 94.3% 18 (χ2 (3) = 1.408, p= 0.704) 110 months (χ2 (5) = 4.359, p= 0.499) 24.4% 35.4% 17.1% 13.4% 9.7% (χ2 (5) = 15.372, p= 0.009) 8.1% 16.3% 27.9% 32.6% 15.1% 48.8% 2.49 N= 102(54%) 29.4% 70.6% 36 (sd=6.7) 97.1% 2.0% 78.4% 17.6% 3.9% 5.0% 30.0% 45.0% 12.0% 8.0% 1.1% 27.7% 18.1% 14.9% 38.3% 4.9% 95.1% 17 100 months 22.2% 28.9% 16.7% 18.9% 13.3% 5.9% 11.8% 14.7% 35.3% 32.4% 39.0% 4.60 Fig. 2 Binary Logistic Regression of Demographic Factors Which Predict Breaks in MMT Breaks in treatment Odds ratio 95% Confidence P-Value Explanatory variable interval 0.93 (0.89, 0.98) .018 Age 1.19 (0.90, 1.57) .201 Marital Status 0.81 (0.64, 1.03) .087 Type of Housing Fig. 3 Current Methadone Dose and Prevalence of Breaks in Treatment >100 81-100 61-80 No Break 41-60 Break 21-40 0-20 0 10 20 30 40 Fig. 4 Duration of Breaks in Treatment By Gender >12 months 6-12 months Female 1-6 months Male <1 month 0 5 10 15 20 25