Sample ID 1780T Organ Age Lung 69 Gender Male Cancer Type Adenosquamous Carcinoma Grade 3 DIAGNOSIS Specimens #1 through #4 - Left Upper Lobe Lung, Lobectomy: PRIMARY TUMOR DIAGNOSIS (CELL TYPE): - ADENOSQUAMOUS CARCINOMA. SEE NOTE. DEGREE OF DIFFERENTIATION: Poor SIZE OF TUMOR: 6.0 x 4.0 x 3.0 cm HISTOLOGIC GRADE: III Poorly differentiated EXTENT OF PRIMARY: Tumor surrounded by lung and not invading visceral pleura. ADDITIONAL TUMOR FEATURES: Lymphatic vessel invasion in lung: Not identified Blood vessel invasion in lung: Not identified Comments: Lymphoplasmacytic response: Mild Stromal response: Absent Tumor necrosis: Present Additional tumor nodules: None MARGINS OF RESECTION: Bronchial Margin: Negative for tumor. LYMPH NODES (HILAR AND PERIBRONCHIAL - Specimen #2): (Stations 10 to 14): Number examined: 3 Number positive: 0 LYMPH NODES (MEDIASTINAL - Specimens #3-4): (Stations 6 and 7): Number examined: 2 Number positive: 0 METASTASIS: No NON NEOPLASTIC LUNG TISSUE: A. Associated Obstructive Pneumonia: None B. Other: - Atelectasis: No - Emphysema: Yes - Granulomas: No - Emboli: No - Scars: No - Infarcts: No pTNM STAGE: Primary Tumor pT2 Tumor with any of the following features of size or extent: More than 3 cm in greatest dimension Regional Lymph Nodes pN0 No regional lymph node metastasis. Metastasis pMX Cannot be assessed. Specimen #5 - Mediastinal Lymph Node, Biopsy: - Benign lymph node (0/1). STAGE GROUPING: Stage IB pT2 N0 MX Note: Tumor cells are focally positive for mucin. Immunohistochemistry shows that the tumor cells are: CK7 p63 PSA PAP POSITIVE Focally positive (>10% squamous) Negative Negative REFERENCE: 1. AJCC Cancer Staging Manual. Lippincott-Raven Press. 6th edition. 2002 (pg.167 - 177). -----------------------------Family history: noncontributory Personal history: smoker- up to 2 pks/day, COPD, emphysema, prostate adenocarcinoma