Publications for Robert Baxter
Publications for Robert Baxter
2016
Liu, C., Teh, R., Mozar, C., Baxter, R.,
Rasmussen, H. (2016). Silencing overexpression
of FXYD3 protein in breast cancer cells
amplifies effects of doxorubicin and γ-radiation
on Na+/K+-ATPase and cell survival. Breast
Cancer Research and Treatment, 155(2),
203-213. <a
href="http://dx.doi.org/10.1007/s10549-015-366
7-x">[More Information]</a>
2015
Chung, L., Phillips, L., Lin, Z., Moore, K.,
Marsh, D., Boyle, F., Baxter, R. (2015). A novel
truncated form of S100P predicts disease-free
survival in patients with lymph node positive
breast cancer. Cancer Letters, 368(1), 64-70. <a
href="http://dx.doi.org/10.1016/j.canlet.2015.07.
046">[More Information]</a>
Song (Wen Chao), W., McLennan, S., Tam, C.,
Williams, P., Baxter, R., Twigg, S. (2015).
CCN2 requires TGF-β signalling to regulate
CCAA
T/enhancer binding proteins and inhibit fat cell
differentiation. Journal of Cell Communication
and Signaling, 9(1), 27-36. <a
href="http://dx.doi.org/10.1007/s12079-014-025
2-8">[More Information]</a>
Baxter, R. (2015). How IGF-1 activates its
receptor. Journal of Cell Communication and
Signaling, 9(1), 87-87. <a
href="http://dx.doi.org/10.1007/s12079-015-027
6-8">[More Information]</a>
Baxter, R. (2015). IGFBP special issue introduction. Journal of Cell Communication and
Signaling, 9(2), 109-109. <a
href="http://dx.doi.org/10.1007/s12079-015-029
5-5">[More Information]</a>
Pon, C., Firth, S., Baxter, R. (2015). Involvement
of insulin-like growth factor binding protein-3 in
peroxisome proliferator-activated receptor
gamma-mediated inhibition of breast cancer cell
growth. Molecular And Cellular Endocrinology,
399, 354-361. <a
href="http://dx.doi.org/10.1016/j.mce.2014.10.02
3">[More Information]</a>
Marzec, K., Lin, Z., Martin, J., Baxter, R. (2015).
Involvement of p53 in insulin-like growth factor
binding protein-3 regulation in the breast cancer
cell response to DNA damage. Oncotarget,
6(29), 26583-26598. <a
href="http://dx.doi.org/10.18632/oncotarget.561
2">[More Information]</a>
Chua, M., Lin, Z., Martin, J., Baxter, R. (2015).
Involvement of the insulin-like growth factor
binding proteins in the cancer cell response to
DNA damage. Journal of Cell Communication
and Signaling, 9(2), 167-176. <a
href="http://dx.doi.org/10.1007/s12079-015-026
2-1">[More Information]</a>
Baxter, R. (2015). Nuclear Actions of
Insulin-like Growth Factor Binding Protein-3.
Gene, 569, 7-13. <a
href="http://dx.doi.org/10.1016/j.gene.2015.06.0
28">[More Information]</a>
Marzec, K., Baxter, R., Martin, J. (2015).
Targeting Insulin-Like Growth Factor Binding
Protein-3 Signaling in Triple-Negative Breast
Cancer. BioMed Research International, 2015,
1-8. <a
href="http://dx.doi.org/10.1155/2015/638526">[
More Information]</a>
2014
Hoyos, C., Killick, R., Keenan, D., Baxter, R.,
Veldhuis, J., Liu, P. (2014). Continuous Positive
Airway Pressure Increases Pulsatile Growth
Hormone Secretion and Circulating Insulin-like
Growth Factor-1 in a Time-Dependent Manner in
Men With Obstructive Sleep Apnea: A
Randomized Sham-Controlled Study. Sleep,
37(4), 733-741. <a
href="http://dx.doi.org/10.5665/sleep.3580">[M
ore Information]</a>
Wong, M., Xue, A., Julovi, S., Pavlakis, N.,
Samra, J., Hugh, T., Gill, A., Peters, L., Baxter,
R., Smith, R. (2014). Cotargeting of epidermal
growth factor receptor and PI3K overcomes
PI3K-Akt oncogenic dependence in pancreatic
ductal adenocarcinoma. Clinical Cancer
Research, 20(10), 4047-4058. <a
href="http://dx.doi.org/10.1158/1078-0432.CCR13-3377">[More Information]</a>
Pillai, U., Phillips, K., Wilkins, G., Baxter, R.,
Benn, D., Parker, N., Smith, R., Marsh, D.
(2014). Factors that may influence the
willingness of cancer patients to consent for
biobanking. Biopreservation and Biobanking,
12(6), 409-414. <a
href="http://dx.doi.org/10.1089/bio.2014.0039">
[More Information]</a>
Baxter, R. (2014). IGF binding proteins in
cancer: mechanistic and clinical insights. Nature
Reviews. Cancer, 14(5), 329-341. <a
href="http://dx.doi.org/10.1038/nrc3720">[More
Information]</a>
Martin, J., de Silva, H., Lin, Z., Scott, C., Baxter,
R. (2014). Inhibition of insulin-like growth factor
binding protein-3 signaling through sphingosine
kinase 1 sensitizes triple-negative breast cancer
cells to EGF receptor blockade. Molecular
Cancer Therapeutics, 13(2), 316-328. <a
href="http://dx.doi.org/10.1158/1535-7163.MCT
Publications for Robert Baxter
-13-0367">[More Information]</a>
Chung, L., Katrina, M., Phillips, L., Boyle, F.,
Marsh, D., Baxter, R. (2014). Novel serum
protein biomarker panel revealed by mass
spectrometry and its prognostic value in breast
cancer. Breast Cancer Research, 16(3), 1-12. <a
href="http://dx.doi.org/10.1186/bcr3676">[More
Information]</a>
Lin, M., Marzec, K., Martin, J., Baxter, R.
(2014). The role of insulin-like growth factor
binding protein-3 in the breast cancer cell
response to DNA-damaging agents. Oncogene,
33(1), 85-96. <a
href="http://dx.doi.org/10.1038/onc.2012.538">[
More Information]</a>
2013
Greenall, S., Bentley, J., Pearce, L., Scoble, J.,
Sparrow, L., Bartone, N., Xiao, X., Baxter, R.,
Cosgrove, L., Adams, T. (2013). Biochemical
Characterization of Individual Human
Glycosylated pro-Insulin-like Growth Factor
(IGF)-II and big-IGF-II Isoforms Associated
with Cancer. Journal of Biological Chemistry,
288(1), 59-68. <a
href="http://dx.doi.org/10.1074/jbc.M112.43201
3">[More Information]</a>
Soon, P., Kim, E., Pon, C., Gill, A., Moore, K.,
Spillane, A., Benn, D., Baxter, R. (2013). Breast
cancer-associated fibroblasts induce
epithelial-to-mesenchymal transition in breast
cancer cells. Endocrine-Related Cancer, 20(1),
1-12. <a
href="http://dx.doi.org/10.1530/ERC-12-0227">[
More Information]</a>
Grkovic, S., O'Reilly, V., Han, S., Hong, M.,
Baxter, R., Firth, S. (2013). IGFBP-3 binds
GRP78, stimulates autophagy and promotes the
survival of breast cancer cells exposed to adverse
microenvironments. Oncogene, 32(19),
2412-2420. <a
href="http://dx.doi.org/10.1038/onc.2012.264">[
More Information]</a>
Baxter, R. (2013). Insulin-like growth factor
binding protein-3 (IGFBP-3): novel ligands
mediate unexpected functions. Journal of Cell
Communication and Signaling, 7(3), 179-189. <a
href="http://dx.doi.org/10.1007/s12079-013-020
3-9">[More Information]</a>
Schedlich, L., Yenson, V., Baxter, R. (2013).
TGF-beta-induced expression of IGFBP-3
regulates IGF1R signaling in human
osteosarcoma cells. Molecular And Cellular
Endocrinology, 377(1-2), 56-64. <a
href="http://dx.doi.org/10.1016/j.mce.2013.06.03
3">[More Information]</a>
Chung, L., Shibli, S., Moore, K., Elder, E.,
Boyle, F., Marsh, D., Baxter, R. (2013). Tissue
biomarkers of breast cancer and their association
with conventional pathologic features. British
Journal of Cancer, 108(2), 351-360. <a
href="http://dx.doi.org/10.1038/bjc.2012.552">[
More Information]</a>
2012
Leong, S., McKay, M., Christopherson, R.,
Baxter, R. (2012). Biomarkers of Breast Cancer
Apoptosis Induced by Chemotherapy and
TRAIL. Journal of Proteome Research, 11(2),
1240-1250. <a
href="http://dx.doi.org/10.1021/pr200935y">[M
ore Information]</a>
Chung, L., Baxter, R. (2012). Breast cancer
biomarkers: proteomic discovery and translation
to clinically relevant assays. Expert Review of
Proteomics, 9(6), 599-614. <a
href="http://dx.doi.org/10.1586/epr.12.62">[Mor
e Information]</a>
Birzniece, V., Meinhardt, U., Gibney, J.,
Johannsson, G., Armstrong, N., Baxter, R., Ho,
K. (2012). Differential Effects of Raloxifene and
Estrogen on Body Composition in Growth
Hormone-Replaced Hypopituitary Women.
Journal of Clinical Endocrinology and
Metabolism, 97(3), 1005-1012. <a
href="http://dx.doi.org/10.1210/jc.2011-2837">[
More Information]</a>
Xue, A., Gandy, R., Chung, L., Baxter, R.,
Smith, R. (2012). Discovery of diagnostic
biomarkers for pancreatic cancer in
immunodepleted serum by SELDI-TOF MS.
Pancreatology, 12(2), 124-129. <a
href="http://dx.doi.org/10.1016/j.pan.2012.02.00
9">[More Information]</a>
Mertens, I., Baxter, R., Marsh, D. (2012).
Gonadotropin signalling in epithelial ovarian
cancer. Cancer Letters, 324(2), 152-159. <a
href="http://dx.doi.org/10.1016/j.canlet.2012.05.
017">[More Information]</a>
Gribben, L., Baxter, R., Marsh, D. (2012).
Insulin-like growth factor binding protein-3
inhibits migration of endometrial cancer cells.
Cancer Letters, 317(1), 41-48. <a
href="http://dx.doi.org/10.1016/j.canlet.2011.11.
011">[More Information]</a>
de Silva, H., Firth, S., Twigg, S., Baxter, R.
(2012). Interaction Between IGF Binding
Protein-3 and TGFb in in the Regulation of
Adipocyte Differentiation. Endocrinology,
153(10), 4799-4807. <a
href="http://dx.doi.org/10.1210/en.2011-1444">[
More Information]</a>
Leong, S., Nunez, A., Lin, Z., Crossett, B.,
Christopherson, R., Baxter, R. (2012).
iTRAQ-Based Proteomic Profiling of Breast
Cancer Cell Response to Doxorubicin and
Publications for Robert Baxter
TRAIL. Journal of Proteome Research, 11(7),
3561-3572. <a
href="http://dx.doi.org/10.1021/pr2012335">[M
ore Information]</a>
Jarajapu, Y., Cai, J., Yan, Y., Calzi, S.,
Kielczewski, J., Hu, P., Shaw, L., Firth, S.,
Chan-Ling, T., Boulton, M., Baxter, R., et al
(2012). Protection of Blood Retinal Barrier and
Systemic Vasculature by Insulin-Like Growth
Factor Binding Protein-3. PloS One, 7(7), 1-16.
<a
href="http://dx.doi.org/10.1371/journal.pone.003
9398">[More Information]</a>
Xue, A., Chang, J., Chung, L., Samra, J., Hugh,
T., Gill, A., Butterini, G., Baxter, R., Smith, R.
(2012). Serum apolipoprotein C-II is prognostic
for survival after pancreatic resection for
adenocarcinoma. British Journal of Cancer,
107(11), 1883-1891. <a
href="http://dx.doi.org/10.1038/bjc.2012.458">[
More Information]</a>
2011
Firth, S., Yan, X., Baxter, R. (2011). D440N
Mutation in the Acid-Labile Subunit of
Insulin-Like Growth Factor Complexes Inhibits
Secretion and Complex Formation. Molecular
Endocrinology, 25(2), 307-314. <a
href="http://dx.doi.org/10.1210/me.2010-0295">
[More Information]</a>
Gielen, M., Mesotten, D., Brugts, M., Coopmans,
W., Van Herck, E., Vanhorebeek, L., Baxter, R.,
Lamberts, S., Janssen, J., Van den Berghe, G.
(2011). Effect of Intensive Insulin Therapy on
the Somatotropic Axis of Critically Ill Children.
Journal of Clinical Endocrinology and
Metabolism, 96(8), 2558-2566. <a
href="http://dx.doi.org/10.1210/jc.2010-3045">[
More Information]</a>
Kielczewski, J., Calzi, S., Shaw, L., Cai, J., Qi,
X., Ruan, Q., Wu, L., Liu, L., Hu, P., Chan-Ling,
T., Firth, S., Baxter, R., et al (2011). Free
insulin-like growth factor binding protein-3
(IGFBP-3) reduces retinal vascular permeability
in association with a reduction of acid
sphingomyelinase (ASMase). Investigative
Ophthalmology and Visual Science, 52(11),
8278-8286. <a
href="http://dx.doi.org/10.1167/iovs.11-8167">[
More Information]</a>
Martin, J., Baxter, R. (2011). Signalling
pathways of insulin-like growth factors (IGFs)
and IGF binding protein-3. Growth Factors,
29(6), 235-244. <a
href="http://dx.doi.org/10.3109/08977194.2011.
614237">[More Information]</a>
2010
Xue, A., Scarlett, C., Chung, L., Butturini, G.,
Scarpa, A., Gandy, R., Wilson, S., Baxter, R.,
Smith, R. (2010). Discovery of serum
biomarkers for pancreatic adenocarcinoma using
proteomic analysis. British Journal of Cancer,
103(3), 391-400. <a
href="http://dx.doi.org/10.1038/sj.bjc.6605764">
[More Information]</a>
Clifton, V., Hodyl, N., Murphy, V., Giles, W.,
Baxter, R., Smith, R. (2010). Effect of maternal
asthma, inhaled glucocorticoids and cigarette use
during pregnancy on the newborn insulin-like
growth factor axis. Growth Hormone and IGF
Research, 20(1), 39-48. <a
href="http://dx.doi.org/10.1016/j.ghir.2009.07.00
4">[More Information]</a>
Mertens, I., Bolitho (nee Donald), C., Baxter,
R., Marsh, D. (2010). Gonadotropin-induced
ovarian cancer cell migration and proliferation
require extracellular signal-regulated kinase 1/2
activation regulated by calcium and protein
kinase Cdelta. Endocrine-Related Cancer, 17(2),
335-349. <a
href="http://dx.doi.org/10.1677/ERC-09-0152">[
More Information]</a>
Yan, X., Baxter, R., Firth, S. (2010).
Involvement of pregnancy-associated plasma
protein-A2 in insulin-like growth factor (IGF)
binding protein-5 proteolysis during pregnancy:
a potential mechanism for increasing IGF
bioavailability. Journal of Clinical
Endocrinology and Metabolism, 95(3),
1412-1420. <a
href="http://dx.doi.org/10.1210/jc.2009-2277">[
More Information]</a>
Birzniece, V., Meinhardt, U., Gibney, J.,
Johannsson, G., Baxter, R., Seibel, M., Ho, K.
(2010). Modulatory Effect of Raloxifene and
Estrogen on the Metabolic Action of Growth
Hormone in Hypopituitary Women. Journal of
Clinical Endocrinology and Metabolism, 95(5),
2099-2106. <a
href="http://dx.doi.org/10.1210/jc.2009-2743">[
More Information]</a>
Bolitho (nee Donald), C., Hahn, M., Baxter, R.,
Marsh, D. (2010). The chemokine CXCL1
induces proliferation in epithelial ovarian cancer
cells by transactivation of the epidermal growth
factor receptor. Endocrine-Related Cancer,
17(4), 929-940. <a
href="http://dx.doi.org/10.1677/ERC-10-0107">[
More Information]</a>
Westwood, M., Maqsood, A., Solomon, M.,
Whatmore, A., Davis, J., Baxter, R., Gevers, E.,
Robinson, I., Clayton, P. (2010). The effect of
different patterns of growth hormone
administration on the IGF axis and somatic and
skeletal growth of the dwarf rat. American
Journal of Physiology: Endocrinology and
Publications for Robert Baxter
Metabolism, 298, E467-E476. <a
href="http://dx.doi.org/10.1152/ajpendo.00234.2
009">[More Information]</a>
A. H. Wass (Eds.), Clinical Endocrine Oncology
- 2nd Edition, (pp. 576-581). United Kingdom:
Blackwell Publishers.
2009
Chuang, S., Patton, K., Schafernak, K.,
Papavero, V., Lin, F., Baxter, R., Teh, B., Yang,
X. (2008). Over expression of insulin-like
growth factor binding protein 3 in clear cell renal
cell carcinoma. The Journal of Urology, 179(2),
445-449. <a
href="http://dx.doi.org/10.1016/j.juro.2007.09.10
6">[More Information]</a>
Baxter, R., Twigg, S. (2009). Actions of IGF
binding proteins and related proteins in adipose
tissue. Trends in Endocrinology and Metabolism,
20(10), 499-505. <a
href="http://dx.doi.org/10.1016/j.tem.2009.07.00
2">[More Information]</a>
Yan, X., Payet, L., Baxter, R., Firth, S. (2009).
Activity of human pregnancy insulin-like growth
factor binding protein-3: determination by
reconstituting recombinant complexes.
Endocrinology, 150(11), 4968-4976. <a
href="http://dx.doi.org/10.1210/en.2009-0090">[
More Information]</a>
Chung, L., Baxter, R. (2009). Detection of
growth hormone responsive proteins using
SELDI-TOF mass spectrometry. Growth
Hormone and IGF Research, 19(4), 383-387. <a
href="http://dx.doi.org/10.1016/j.ghir.2009.04.01
9">[More Information]</a>
O'Han, M., Baxter, R., Schedlich, L. (2009).
Effects of endogenous insulin-like growth factor
binding protein-3 on
cell cycle regulation in breast cancer cells.
Growth Factors, 27(6), 394-408. <a
href="http://dx.doi.org/10.3109/0897719090318
5032">[More Information]</a>
Chan, S., Schedlich, L., Twigg, S., Baxter, R.
(2009). Inhibition of adipocyte differentiation by
insulin-like growth factor-binding protein-3.
American Journal of Physiology: Endocrinology
and Metabolism, 296(4), E654-E663. <a
href="http://dx.doi.org/10.1152/ajpendo.90846.2
008">[More Information]</a>
Martin, J., Lin, Z., McGowan, E., Baxter, R.
(2009). Potentiation of growth factor signaling
by insulin-like growth factor binding protein-3 in
breast epithelial cells requires sphingosine kinase
activity. Journal of Biological Chemistry,
284(38), 25542-25552. <a
href="http://dx.doi.org/10.1074/jbc.M109.00712
0">[More Information]</a>
Chung, L., Nelson, A., Ho, K., Baxter, R. (2009).
Proteomic profiling of growth
hormone-responsive proteins in human
peripheral blood leukocytes. Journal of Clinical
Endocrinology and Metabolism, 94(8),
3038-3043. <a
href="http://dx.doi.org/10.1210/jc.2009-0778">[
More Information]</a>
Nelson, A., Meinhardt, U., Hansen, J., Walker,
I., Stone, G., Howe, C., Leung, K., Seibel, M.,
Baxter, R., Handelsman, D., et al (2008).
Pharmacodynamics of Growth Hormone abuse
biomarkers and the influence of gender and
testosterone: a randomized double-blind
placebo-controlled study in young recreational
athletes. Journal of Clinical Endocrinology and
Metabolism, 93(6), 2213-2222. <a
href="http://dx.doi.org/10.1210/jc.2008-0402">[
More Information]</a>
Gosby, A., Stanton, L., Maloney, C., Thompson,
M., Briody, J., Baxter, R., Bryson, J., Denyer, G.,
Caterson, I. (2008). Postnatal nutrition alters
body composition in adult offspring exposed to
maternal protein restriction. British Journal of
Nutrition, 101(2), 1878-1884. <a
href="http://dx.doi.org/10.1017/S000711450813
5851">[More Information]</a>
Marsh, D., Trahair, T., Martin, J., Chee, W.,
Walker, J., Kirk, E., Baxter, R., Marshall, G.
(2008). Rapamycin treatment for a child with
germline
PTEN mutation. Nature Clinical Practice
Oncology, 5(6), 357-361. <a
href="http://dx.doi.org/10.1038/ncponc1112">[
More Information]</a>
Nguyen, T., Nelson, A., Howe, C., Seibel, M.,
Baxter, R., Handelsman, D., Kazlauskas, R., Ho,
K. (2008). Within-Subject Variability and
Analytic Imprecision of Insulinlike Growth
Factor Axis and Collagen Markers: Implications
for Clinical Diagnosis and Doping Tests.
Clinical Chemistry, 54(8), 1268-1276. <a
href="http://dx.doi.org/10.1373/clinchem.2008.1
05726">[More Information]</a>
2007
2008
Scarlett, C., Samra, J., Xue, A., Baxter, R.,
Smith, R. (2007). Classification of pancreatic
cystic lesions using seldi-tof mass spectrometry.
ANZ Journal of Surgery, 77(8), 648-653. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17635277">[More Information]</a>
Baxter, R. (2008). Insulin-like Growth Factors
and Tumor Hypoglycemia. In Ian D. Hay, John
Martin, J., Baxter, R. (2007). Expression of
insulin-like growth factor binding protein-2 by
Publications for Robert Baxter
MCF-7 breast cancer cells is regulated through
the phosphatidylinositol
3-kinase/AKT/mammalian target of rapamycin
pathway. Endocrinology, 148(5), 2532-2541. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17289850">[More Information]</a>
Baxter, R., Smith, R., Scarlett, C., Xue, A.,
Butturini, G., Scarpa, A. (2007). Hp07 proteomic
identification of serum markers of pancreatic
adenocarcinoma using seldi-tof ms. ANZ Journal
of Surgery, 77(suppl.1), A41-A41. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17490146">[More Information]</a>
Schedlich, L., Muthukaruppan, A., O'Han, M.,
Baxter, R. (2007). Insulin-Like Growth Factor
Binding Protein-5 Interacts with the Vitamin D
Receptor and Modulates the Vitamin D Response
in Osteoblasts. Molecular Endocrinology,
21(10), 2378-2390. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17595320">[More Information]</a>
Schedlich, L., Graham, L., O'Han, M.,
Muthukaruppan, A., Yan, X., Firth, S., Baxter, R.
(2007). Molecular basis of the interaction
between IGFBP-3 and retinoid X receptor: Role
in modulation of RAR-signaling. Archives of
Biochemistry and Biophysics, 465(2), 359-369.
<a
href="http://dx.doi.org/10.1016/j.abb.2007.06.01
3">[More Information]</a>
Leong, S., Christopherson, R., Baxter, R. (2007).
Profiling of apoptotic changes in human breast
cancer cells using SELDI-TOF mass
spectrometry. Cellular Physiology and
Biochemistry, 20(5), 579-590. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17762184">[More Information]</a>
Graham, M., Kilby, D., Firth, S., Robinson, P.,
Baxter, R. (2007). The in vivo phosphorylation
and glycosylation of human insulin-like growth
factor binding protein-5. Molecular and Cellular
Proteomics, 6(8), 1392-1405. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17496250">[More Information]</a>
2006
Nelson, A., Howe, C., Nguyen, T., Leung, K.,
Trout, G., Seibel, M., Baxter, R., Handelsman,
D., Kazlauskas, R., Ho, K. (2006). Influence of
demographic factors and sport type on growth
hormone-responsive markers in elite athletes.
Journal of Clinical Endocrinology and
Metabolism, 91(11), 4424-4432. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16912136">[More Information]</a>
Baxter, R., Chung, L., Clifford, D., Buckley, M.
(2006). Novel biomarkers of human growth
hormone action from serum proteomic profiling
using protein chip mass spectrometry. Journal of
Clinical Endocrinology and Metabolism, 91(2),
671-677. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16303837">[More Information]</a>
Santer, F., Bacher, N., Moser, B., Morandell, D.,
Ressler, S., Firth, S., Spoden, G., Sergi, C.,
Baxter, R., Jansen-Durr, P., et al (2006). Nuclear
insulin-like growth factor binding protein-3
induces apoptosis and is targeted to
ubiquitin/proteasome-dependent proteolysis.
Cancer Research, 66(6), 3024-3033. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16540651">[More Information]</a>
Marsh, D., Baxter, R., Moscova, M. (2006).
Protein chip discovery of secreted proteins
regulated by the phosphatidylinositol 3-kinase
pathway in ovarian cancer cell lines. Cancer
Research, 66(3), 1376-1383. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16452192">[More Information]</a>
Scarlett, C., Smith, R., Saxby, A., Nielsen, A.,
Samra, J., Wilson, S., Baxter, R. (2006).
Proteomic classification of pancreatic
adenocarcinoma tissue using protein chip
technology. Gastroenterology, 130(6),
1670-1678. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16697731">[More Information]</a>
Bell, C., Samra, J., Hugh, T., Baxter, R., Smith,
R., Saxby, A., Nielsen, A., Scarlett, C. (2006).
Proteomic profiling of cholangiocarcinoma:
Diagnostic potential of SELDI-TOF MS in
malignant bile duct stricture. Hepatology, 44(3),
658-666. <a
href="http://dx.doi.org/10.1002/hep.21294">[Mo
re Information]</a>
Yan, X., Baxter, R., Perbal, B., Firth, S. (2006).
The aminoterminal insulin-like growth factor
(IGF) binding domain of IGF binding protein-3
cannot be functionally substituted by the
structurally homologous domain of CCN3.
Endocrinology, 147(11), 5268-5274. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16935848">[More Information]</a>
2005
Takahashi, M., Papavero, V., Yuhas, J., Kort, E.,
Publications for Robert Baxter
Kanayama, H., Kagawa, S., Baxter, R., Yang, X.,
Gray, S., Teh, B. (2005). Altered expression of
members of the IGF-axis in clear cell renal cell
carcinoma. International Journal of Oncology,
26(4), 923-31. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15753986">[More Information]</a>
Sevette, A., Smith, R., Aslani, A., Kee, A.,
Hansen, R., Barratt, S., Baxter, R. (2005). Does
growth hormone allow more efficient nitrogen
sparing in postoperative patients requiring
parenteral nutrition? A double-blind,
placebo-controlled randomised trial. Clinical
Nutrition, 24(6), 943-955. <a
href="http://dx.doi.org/10.1016/j.clnu.2005.06.0
06">[More Information]</a>
Butt, A., Dickson, K., Jambazov, S., Baxter, R.
(2005). Enhancement of tumor necrosis
factor-alpha-induced growth inhibition by
insulin-like growth factor-binding protein-5
(IGFBP-5), but not IGFBP-3 in human breast
cancer cells. Endocrinology, 146(7), 3113-3122.
<a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15802501">[More Information]</a>
Nelson, A., Howe, C., Nguyen, T., Seibel, M.,
Baxter, R., Handelsman, D., Kazlauskas, R., Ho,
K. (2005). Erythropoietin administration does
not influence the GH-IGF axis or makers of bone
turnover in recreational athletes. Clinical
Endocrinology, 63(3), 305-309. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16117818">[More Information]</a>
Moscova, M., Marsh, D., Baxter, R. (2005).
Identification of Cytokines regulated by
phosphatidylinositol-3 kinase in ovarian cancer.
AACR-NCI-EORTC International Conference
2005, United States: American Association for
Cancer Research.
Chan, S., Twigg, S., Firth, S., Baxter, R. (2005).
Insulin-like growth factor binding protein-3 leads
to insulin resistance in adipocytes. Journal of
Clinical Endocrinology and Metabolism, 90(12),
6588-6595. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16189260">[More Information]</a>
Brand-Miller, J., Liu, V., Petocz, P., Baxter, R.
(2005). The glycemic index of foods influences
postprandial insulin-like growth factor-binding
protein responses in lean young subjects. The
American Journal of Clinical Nutrition, 82(2),
350-354. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16087978">[More Information]</a>
Healy, M., Dall, R., Gibney, J., Bassett, E.,
Ehrnborg, C., Pentecost, C., Rosen, T., Cittadini,
A., Baxter, R., Sönksen, P. (2005). Toward the
Development of a Test for Growth Hormone
(GH) Abuse: A Study of Extreme Physiological
Ranges of GH-Dependent Markers in 813 Elite
Athletes in the Postcompetition Setting. Journal
of Clinical Endocrinology and Metabolism,
90(2), 641-649.
2004
Scarlett, C., O'Leary, M., Lee, A., Nielsen, A.,
Sevette, A., Baxter, R., Smith, R. (2004). A
Study Of Parenteral Versus Enteral Nutrition
Following Caecal Ligation And Puncture In The
Rat: Influence On Survival And Tissue Protein
Turnover. Clinical Nutrition, 23(5), 1135-1145.
<a
href="http://dx.doi.org/10.1016/j.clnu.2004.02.0
08">[More Information]</a>
Butt, A., Martin, J., Dickson, K., McDougall, F.,
Firth, S., Baxter, R. (2004). Insulin-Like Growth
Factor Binding Protein-3 Expression Is
Associated With Growth Stimulation Of T47D
Human Breast Cancer Cells: The Role Of
Altered Epidermal Growth Factor Signaling.
Journal of Clinical Endocrinology and
Metabolism, 89(4), 1950-1956.
Schedlich, L., O'Han, M., Leong, G., Baxter, R.
(2004). Insulin-Like Growth Factor Binding
Protein-3 Prevents Retinoid Receptor
Heterodimerization: Implications For Retinoic
Acid-Sensitivity In Human Breast Cancer Cells.
Biochemical and Biophysical Research
Communications, 314(1), 83-88. <a
href="http://dx.doi.org/10.1016/j.bbrc.2003.12.0
49">[More Information]</a>
Mesotten, D., Wouters, P., Peeters, R., Hardman,
K., Holly, J., Baxter, R., Van den Berghe, G.
(2004). Regulation Of The Somatotropic Axis
By Intensive Insulin Therapy During Protracted
Critical Illness. Journal of Clinical
Endocrinology and Metabolism, 89(7),
3105-3113.
Yan, X., Forbes, B., McNeil, K., Baxter, R.,
Firth, S. (2004). Role Of N- And C-Terminal
Residues Of Insulin-Like Growth Factor
(IGF)-Binding Protein-3 In Regulating IGF
Complex Formation And Receptor Activation.
Journal of Biological Chemistry, 279(51),
53232-53240.
Payet, L., Firth, S., Baxter, R. (2004). The Role
Of The Acid-Labile Subunit In Regulating
Insulin-Like Growth Factor Transport Across
Human Umbilical Vein Endothelial Cell
Monolayers. Journal of Clinical Endocrinology
and Metabolism, 89(5), 2382-2389.
Publications for Robert Baxter
2003
Payet, L., Wang, X., Baxter, R., Firth, S. (2003).
Amino-and carboxyl-terminal fragments of
insulin-like growth factor (IGF) binding
protein-3 cooperate to bind IGFs with high
affinity and inhibit IGF receptor interactions.
Endocrinology, 144(7), 2797-2806.
Baxter, R., Fanayan, S. (2003). Functional
relationships between transforming growth
factor-beta and the insulin-like growth factor
binding proteins. In Leroith, Zimkeller, Baxter
(Eds.), Insulin-Like Growth Factors, (pp.
281-293). New York: Springer.
Mesotten, D., Van den Berghe, G., Liddle, C.,
Coulter, S., McDougall, F., Baxter, R., Delhanty,
P. (2003). Growth hormone modulation of the rat
hepatic bile transporter system in
endotoxin-induced cholestasis. Endocrinology,
144(9), 4008-4017.
Srinivasan, S., Baxter, R., Waters, M., Rowland,
J., Verge, C. (2003). Hyperinsulinism and
overgrowth without obesity. Archives of Disease
in Childhood, 88(4), 332-334.
LeRoith, D., Zumkeller, W., Baxter, R. (2003).
Insulin-like Growth Factor Receptor Signalling.
United States: Springer.
Martin, J., Weenink, S., Baxter, R. (2003).
Insulin-like growth factor-binding protein-3
potentiates epidermal growth factor action in
MCF-10A mammary epithelial cells. Journal of
Biological Chemistry, 278(5), 2969-2976.
Butt, A., Dickson, K., McDougall, F., Baxter, R.
(2003). Insulin-like growth factor-binding
protein-5 inhibits the growth of human breast
cancer cells in vitro and in vivo. Journal of
Biological Chemistry, 278(32), 29676-29685.
Gunton, J., Delhanty, P., Takahashi, S., Baxter,
R. (2003). Metaformin rapidly increases insulin
receptor activation in human liver and signals
preferentially through insulin-receptor
substrate-2. Journal of Clinical Endocrinology
and Metabolism, 88(3), 1323-1332.
Schedlich, L., Nilsen, T., John, A., Jans, D.,
Baxter, R. (2003). Phosphorylation of
insulin-like growth factor binding protein-3 by
deoxyribonucleic acid-dependent protein kinase
reduces ligand binding and enhances nuclear
accumulation. Endocrinology, 144(5),
1984-1993.
Frystyk, J., Nyholm, B., Skjærbæk, C., Baxter,
R., Schmitz, O., Orskov, H. (2003). The
circulating IGF system and its relationship with
24-h glucose regulation and insulin sensitivity in
healthy subjects. Clinical Endocrinology, 58(6),
777-784.
Ehrnborg, C., Lange, K., Dall, R., Christiansen,
J., Lundberg, P., Baxter, R., Boroujerdi, M.,
Bengtsson, B., Healey, M., Pentecost, C., et al
(2003). The growth hormone/insulin-like growth
factor-I axis hormones and bone markers in elite
athletes in response to a maximum exercies test.
Journal of Clinical Endocrinology and
Metabolism, 88(1), 394-401.
2002
Kong, S., Baxter, R., Delhanty, P. (2002).
Age-Dependent Regulation of the Acid-Labile
Subunit in Response to Fasting-Refeeding in
Rats. Endocrinology, 143(12), 4505-4512.
Firth, S., Baxter, R. (2002). Cellular Actions of
the Insulin-like Growth Factor Binding Proteins.
Endocrine Reviews, 23(6), 824-854.
Delhanty, P., Mesotten, D., McDougall, F.,
Baxter, R. (2002). Growth Hormone Rapidly
Induces Resistin Gene Expression in White
Adipose Tissue of Spontaneous Dwarf (SDR)
Rats. Endocrinology, 143(6), 2445-2448.
Butt, A., Fraley, K., Firth, S., Baxter, R. (2002).
IGF-Binding Protein-3-Induced Growth
Inhibition and Apoptosis Do Not Require Cell
Surface Binding and Nuclear Translocation in
Human Breast Cancer Cells. Endocrinology,
143(7), 2693-2699.
Firth, S., McDougall, F., McLachlan, A., Baxter,
R. (2002). Impaired Blockade of Insulin-Like
Growth Factor I (IGF-I)-Induced Hypoglycemia
by IGF Binding Protein-3 Analog with Reduced
Ternary Complex-Forming Ability.
Endocrinology, 143(5), 1669-1676.
Kodama, Y., Baxter, R., Martin, J. (2002).
Insulin-like Growth Factor-I Inhibits Cell
Growth in the A549 Non-Small Lung Cancer
Cell Line. American Journal of Respiratory Cell
and Molecular Biology, 27(3), 336-344.
Baxter, R., Meka, S., Firth, S. (2002). Molecular
Distribution of IGF Binding Protein-5 in Human
Serum. Journal of Clinical Endocrinology and
Metabolism, 87(1), 271-276.
Mesotten, D., Delhanty, P., Vanderhoydonc, F.,
Hardman,, K., Weekers, F., Baxter, R., Van den
Berghe, G. (2002). Regulation of Insulin-Like
Growth Factor Binding Protein-1 during
Protracted Critical Illness. Journal of Clinical
Endocrinology and Metabolism, 87(12),
5516-5523.
Kong, S., Firth, S., Baxter, R., Delhanty, P.
(2002). Regulation of the acid-labile subunit in
sustained endotoxemia. American Journal of
Physiology: Endocrinology and Metabolism, ,
692-701.
Donaghy, A., Delhanty, P., Ho, K., Baxter, R.,
Williams, R. (2002). Regulation of the growth
hormone receptor/binding protein, insulin-like
Publications for Robert Baxter
growth factor ternary complex system in human
cirrhosis. Journal of Hepatology, 36(6), 751-758.
Fanayan, S., Firth, S., Baxter, R. (2002).
Signaling through the Smad Pathway by
Insulin-like Growth Factor-binding Protein-3 in
Breast Cancer Cells: Relationship to
transforming growth factor -β1 signaling.
Journal of Biological Chemistry, 277(9),
7255-7261.
Van den Berghe, G., Baxter, R., Weekers, F.,
Wouters, P., Bowers, C., Iranmanesh, A.,
Veldhuis, J., Bouillon, R. (2002). The combined
administration of GH-releasing peptide-2
(GHRP-2), TRH and GnRH to men with
prolonged critical illness evokes superior
endocrine and metabolic effects compared to
treatment with GHRP-2 alone. Clinical
Endocrinology, 56(5), 655-669.
2001
Delhanty, P., Scott, C., Baxter, R., Babu,, S.
(2001). Acid-labile subunit regulation during the
early stages of liver regeneration: implications
for glucoregulation. American Journal of
Physiology: Endocrinology and Metabolism,
280.
Baxter, R. (2001). Changes in the IGF-IGFBP
axis in critical illness. Best Practice and
Research: Clinical Endocrinology and
Metabolism, 15, 421-434.
Baxter, R., Van, D., Weekers, F., Wouters, P.,
Iranmanesh, A., Bouillon,, R., Veldhuis, J.
(2001). Five-day pulsatile
gonadotropin-releasing hormone administration
unveils combined
hypothalamic-pituitary-gonadal defects
underlying profound hypoandrogenism in men
with prolonged critical illness. Journal of
Clinical Endocrinology and Metabolism, 86,
3217-3226.
Baxter, R., Ranke, M., Feldt-Rasmussen, U.,
Bang,, P., Camacho-Hubner, C., Clemmons,, D.,
Juul, A., Orskov, H., Strasburger, C. (2001).
How should insulin-like growth factor I be
measured? Hormone Research, 55 (suppl),
106-109.
Baxter, R. (2001). Inhibition of the insulin-like
growth factor (IGF)-IGF-binding protein
interaction. Hormone Research, 55 (suppl),
68-72.
Firth, S., Baxter, R., Galanis, M., Bond,, J.,
Nathanielsz, A., Kortt, A., Hudson,, P. (2001).
Ligand-binding characteristics of recombinant
amino-and carboxyl-terminal fragments of
human insulin-like growth factor-binding
protein-3. Journal of Endocrinology, 169,
123-133.
Firth, S., Baxter, R., Clemmons,, D. (2001).
Mutagenesis of basic amino acids in the
carboxyl-terminal region of insulin-like growth
factor binding protein-5 affects acid-labile
subunit binding. Endocrinology, 142(5),
2147-2150.
Sevette, A., Baxter, R., Smith, R., Kee,, A.,
Carlsson, A. (2001). Parenteral nutrition with
lipid or glucose suppresses liver growth and
response to GH in adolescent male rats.
American Journal of Physiology: Endocrinology
and Metabolism, 281.
Baxter, R. (2001). Signalling pathways involved
in antiproliferative effects of IGFBP-3: a review.
Molecular Pathology, 54, 145-148.
Baxter, R. (2001). What is the significance of
IGF-binding protein-3 proteolysis in the
circulation? Journal of Clinical Endocrinology
and Metabolism, 86(10), 5087-5088.