Publications for Fanfan Zhou Publications for Fanfan Zhou 2016 Chan, T., Cheung, F., Zheng, J., Lu, X., Zhu, L., Grewal, T., Murray, M., Zhou, F. (2016). Casein Kinase 2 Is a Novel Regulator of the Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2) Trafficking. Molecular Pharmaceutics, 13(1), 144-154. <a href="http://dx.doi.org/10.1021/acs.molpharmac eut.5b00576">[More Information]</a> Xu, C., Zhu, L., Chan, T., Lu, X., Shen, W., Madigan, M., Gillies, M., Zhou, F. (2016). Chloroquine and Hydroxychloroquine Are Novel Inhibitors of Human Organic Anion Transporting Polypeptide 1A2. Journal of Pharmaceutical Sciences, 105(2), 884-890. <a href="http://dx.doi.org/10.1002/jps.24663">[Mor e Information]</a> Zhu, X., Wang, K., Zhang, K., Xu, F., Yin, Y., Zhu, L., Zhou, F. (2016). Galectin-1 knockdown in carcinoma-associated fibroblasts inhibits migration and invasion of human MDA-MB-231 breast cancer cells by modulating MMP-9 expression. Acta Biochimica et Biophysica Sinica, 29(4), 462-467. <a href="http://dx.doi.org/10.1093/abbs/gmw019">[ More Information]</a> Wang, K., Zhu, X., Zhang, K., Zhou, F., Zhu, L. (2016). Gas1 Knockdown Increases the Neuroprotective Effect of Glial Cell-Derived Neurotrophic Factor Against Glutamate-Induced Cell Injury in Human SH-SY5Y Neuroblastoma Cells. Cellular and Molecular Neurobiology, 36(4), 603-611. <a href="http://dx.doi.org/10.1007/s10571-015-024 1-3">[More Information]</a> Lu, X., Chan, T., Xu, C., Zhu, L., Zhou, Q., Roberts, K., Chan, K., Li, J., Zhou, F. (2016). Human oligopeptide transporter 2 (PEPT2) mediates cellular uptake of polymyxins. Journal of Antimicrobial Chemotherapy, 71(2), 403-412. <a href="http://dx.doi.org/10.1093/jac/dkv340">[M ore Information]</a> Zhu, X., Wang, K., Zhang, K., Lin, X., Zhu, L., Zhou, F. (2016). Puerarin Protects Human Neuroblastoma SH-SY5Y Cells against Glutamate-Induced Oxidative Stress and Mitochondrial Dysfunction. Journal of Biochemical and Molecular Toxicology (Online), 30(1), 22-28. <a href="http://dx.doi.org/10.1002/jbt.21736">[Mor e Information]</a> Zheng, J., Chan, T., Zhu, L., Yan, X., Cao, Z., Wang, Y., Zhou, F. (2016). The inhibitory effects of camptothecin (CPT) and its derivatives on the substrate uptakes mediated by human solute carrier transporters (SLCs). Xenobiotica, 46(9), 831-840. <a href="http://dx.doi.org/10.3109/00498254.2015. 1129080">[More Information]</a> 2015 Wang, K., Xie, M., Zhu, L., Zhu, X., Zhang, K., Zhou, F. (2015). Ciliary neurotrophic factor protects SH-SY5Y neuroblastoma cells against A-Beta1-42-induced neurotoxicity via activating the JAK2/STAT3 axis. Folia Neuropathologica, 53(3), 226-235. <a href="http://dx.doi.org/10.5114/fn.2015.54423"> [More Information]</a> Zhu, L., Shen, W., Lyons, B., Wang, Y., Zhou, F., Gillies, M. (2015). Dysregulation of inter-photoreceptor retinoid-binding protein (IRBP) after induced Muller cell disruption. Journal of Neurochemistry, 133(6), 909-918. <a href="http://dx.doi.org/10.1111/jnc.13075">[Mo re Information]</a> Zhu, X., Liu, A., Zhang, K., Wang, K., Gao, Y., Zhou, F., Zhu, L. (2015). High-yield soluble expression of recombinant human interleukin-1β in Escherichia coli. Romanian Biotechnology Letters, 20(1), 10114-10122. Chan, T., Zhu, L., Madigan, M., Wang, K., Shen, W., Gillies, M., Zhou, F. (2015). Human organic anion transporting polypeptide 1A2 (OATP1A2) mediates cellular uptake of all-trans-retinol in human retinal pigmented epithelial cells. British Journal of Pharmacology, 172(9), 2343-2353. <a href="http://dx.doi.org/10.1111/bph.13060">[Mo re Information]</a> Chan, T., Zheng, J., Zhu, L., Grewal, T., Murray, M., Zhou, F. (2015). Putative Transmembrane Domain 6 of the Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2) Influences Transporter Substrate Binding, Protein Trafficking, and Quality Control. Molecular Pharmaceutics, 12(1), 111-119. <a href="http://dx.doi.org/10.1021/mp500459b">[ More Information]</a> Zhu, X., Wang, K., Zhang, K., Tan, X., Wu, Z., Sun, S., Zhou, F., Zhu, L. (2015). Tetramethylpyrazine Protects Retinal Capillary Endothelial Cells (TR-iBRB2) against IL-1B-Induced Nitrative/Oxidative Stress. International Journal of Molecular Sciences, 16(9), 21775-21790. <a href="http://dx.doi.org/10.3390/ijms160921775" >[More Information]</a> Xu, C., Zhu, L., Chan, T., Lu, X., Shen, W., Gillies, M., Zhou, F. (2015). The altered renal and hepatic expression of solute carrier transporters (SLCs) in type 1 diabetic mice. PloS One, 10(3), 1-14. <a href="http://dx.doi.org/10.1371/journal.pone.012 Publications for Fanfan Zhou 0760">[More Information]</a> 2014 Ren, T., Han, Z., Yang, C., Hang, Y., Fang, D., Wang, K., Zhu, X., Ji, X., Zhou, F. (2014). Association of SLC22A4 gene polymorphism with Rheumatoid arthritis in the Chinese population. Journal of Biochemical and Molecular Toxicology (Online), 28(5), 206-210. <a href="http://dx.doi.org/10.1002/jbt.21554">[Mor e Information]</a> Wang, K., Zhou, F., Zhu, L., Zhu, X., Zhang, K., Zhu, L. (2014). High level soluble expression, purification, and characterization of human ciliary neruonotrophic factor in Escherichia coli by single protein production system. Protein Expression and Purification, 96, 8-13. <a href="http://dx.doi.org/10.1016/j.pep.2014.01.00 8">[More Information]</a> Li, Z., Cheung, F., Zheng, J., Chan, T., Zhu, L., Zhou, F. (2014). Interaction of the Bioactive Flavonol, Icariin, with the Essential Human Solute Carrier Transporters. Journal of Biochemical and Molecular Toxicology (Online), 28(2), 91-97. <a href="http://dx.doi.org/10.1002/jbt.21540">[Mor e Information]</a> Li, Z., Wang, K., Zheng, J., Cheung, F., Chan, T., Zhu, L., Zhou, F. (2014). Interactions of the active components of Punica granatum (pomegranate) with the essential renal and hepatic human Solute Carrier transporters. Pharmaceutical Biology, 52(12), 1510-1517. <a href="http://dx.doi.org/10.3109/13880209.2014. 900809">[More Information]</a> Wang, K., Zhu, X., Zhang, K., Zhu, L., Zhou, F. (2014). Investigation of gallic acid induced anticancer effect in human breast carcinoma MCF-7 cells. Journal of Biochemical and Molecular Toxicology (Online), 28(9), 387-393. <a href="http://dx.doi.org/10.1002/jbt.21575">[Mor e Information]</a> Wang, K., Zhou, F., Zhu, X., Zhang, K., Huang, B., Zhu, L., Zhu, L. (2014). Neuroprotective properties of ciliary neurotrophic factor on retinoic acid (RA)-predifferentiated SH-SY5Y neuroblastoma cells. Folia Neuropathologica, 52(2), 121-127. <a href="http://dx.doi.org/10.5114/fn.2014.43783"> [More Information]</a> Zheng, J., Chan, T., Cheung, F., Zhu, L., Murray, M., Zhou, F. (2014). PDZK1 and NHERF1 Regulate the Function of Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2) by Modulating Its Subcellular Trafficking and Stability. PloS One, 9(4). <a href="http://dx.doi.org/10.1371/journal.pone.009 4712">[More Information]</a> Wang, K., Zhu, L., Zhu, X., Zhang, K., Huang, B., Zhang, J., Zhang, Y., Zhu, L., Zhou, B., Zhou, F. (2014). Protective Effect of Paeoniflorin on AB 25-35- Induced SH-SY5Y Cell Injury by Preventing Mitochondrial Dysfunction. Cellular and Molecular Neurobiology, 34(2), 227-234. <a href="http://dx.doi.org/10.1007/s10571-013-000 6-9">[More Information]</a> Johnston, R., Rawling, T., Chan, T., Zhou, F., Murray, M. (2014). Selective Inhibition of Human Solute Carrier Transporters by Multikinase Inhibitors. Drug Metabolism and Disposition, 42(11), 1851-1857. <a href="http://dx.doi.org/10.1124/dmd.114.059097 ">[More Information]</a> Zhu, X., Xie, M., Wang, K., Zhang, K., Gao, Y., Zhu, L., Zhou, F. (2014). The effect of puerarin against IL-1B-mediated leukostasis and apoptosis in retinal capillary endothelial cells (TR-iBRB2). Molecular Vision, 20, 1815-1823. Wang, K., Zhang, K., Lv, Z., Zhu, X., Zhu, L., Zhou, F. (2014). Ultrasensitive detection of microRNA with isothermal amplification and a time-resolved fluorescence sensor. Biosensors and Bioelectronics, 57, 91-95. <a href="http://dx.doi.org/10.1016/j.bios.2014.01.05 8">[More Information]</a> Zhu, X., Wang, K., Zhang, K., Zhu, L., Zhou, F. (2014). Ziyuglycoside II induces cell cycle arrest and apoptosis through activation of ROS/JNK pathway in human breast cancer cells. Toxicology Letters, 227(1), 65-73. <a href="http://dx.doi.org/10.1016/j.toxlet.2014.03. 015">[More Information]</a> 2013 Cui, P., Rawling, T., Gillani, T., Bourget, K., Wang, X., Zhou, F., Murray, M. (2013). Anti-proliferative actions of N'-desmethylsorafenib in human breast cancer cells. Biochemical Pharmacology, 86(3), 419-427. <a href="http://dx.doi.org/10.1016/j.bcp.2013.05.01 4">[More Information]</a> Zhou, F., Zheng, J., Zhu, L., Jodal, A., Cui, P., Wong, K., Gurney, H., Church, W., Murray, M. (2013). Functional Analysis of Novel Polymorphisms in the Human SLCO1A2 Gene that Encodes the Transporter OATP1A2. The AAPS Journal, 15(4), 1099-1108. <a href="http://dx.doi.org/10.1208/s12248-013-951 5-1">[More Information]</a> Toh, D., Cheung, F., Murray, M., Pern, T., Lee, E., Zhou, F. (2013). Functional Analysis of Novel Variants in the Organic Publications for Fanfan Zhou Cation/Ergothioneine Transporter 1 Identified in Singapore Populations. Molecular Pharmaceutics, 10(7), 2509-2516. <a href="http://dx.doi.org/10.1021/mp400193r">[M ore Information]</a> Chan, T., Li, Z., Zheng, J., Cheung, F., Zhu, L., Zhou, F. (2013). Inhibitory effects of apigenin and kaempferol on the essential solute carrier transporters. World Journal of Pharmacology, 2(4), 115-121. <a href="http://dx.doi.org/10.5497/wjp.v2.i4.115">[ More Information]</a> Wang, K., Pei, H., Huang, B., Zhu, X., Zhang, J., Zhou, B., Zhu, L., Zhang, Y., Zhou, F. (2013). The Expression of ABC Efflux Pump, Rv1217c-Rv1218c, and Its Association with Multidrug Resistance of Mycobacterium tuberculosis in China. Current Microbiology, 66(3), 222-226. <a href="http://dx.doi.org/10.1007/s00284-012-021 5-3">[More Information]</a> Xu, F., Li, Z., Zheng, J., Cheung, F., Chan, T., Zhu, L., Zhuge, H., Zhou, F. (2013). The Inhibitory Effects of the Bioactive Components Isolated from Scutellaria Baicalensis on the Cellular Uptake Mediated by the Essential Solute Carrier Transporters. Journal of Pharmaceutical Sciences, 102(11), 4205-4211. <a href="http://dx.doi.org/10.1002/jps.23727">[Mor e Information]</a> Zhu, X., Wang, K., Zhang, K., Huang, B., Zhang, J., Zhang, Y., Zhu, L., Zhou, B., Zhou, F. (2013). Ziyuglycoside II inhibits the growth of human breast carcinoma MDA-MB-435 cells via cell cycle arrest and induction of apoptosis through the mitochondria dependent pathway. International Journal of Molecular Sciences, 14(9), 18041-18055. <a href="http://dx.doi.org/10.3390/ijms140918041" >[More Information]</a> 2012 Cui, P., Rawling, T., Bourget, K., Kim, T., Duke, C., Doddareddy, M., Hibbs, D., Zhou, F., Tattam, B., Petrovic, N., Murray, M. (2012). Antiproliferative and Antimigratory Actions of Synthetic Long Chain n-3 Monounsaturated Fatty Acids in Breast Cancer Cells That Overexpress Cyclooxygenase-2. Journal of Medicinal Chemistry, 55(16), 7163-7172. <a href="http://dx.doi.org/10.1021/jm300673z">[M ore Information]</a> Zhou, F., Li, Z., Lam, P., Zhu, L., Wang, K. (2012). Current Updates in the Genetic Polymorphisms of Human Organic Anion Transporters (OATs). Journal of Pharmacogenomics & Pharmacoproteomics, 3(6), 1-8. <a href="http://dx.doi.org/10.4172/2153-0645.1000 e127">[More Information]</a> Ghassabian, S., Rawling, T., Zhou, F., Doddareddy, M., Tattam, B., Hibbs, D., Edwards, R., Cui, P., Murray, M. (2012). Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites. Biochemical Pharmacology, 84(2), 215-223. <a href="http://dx.doi.org/10.1016/j.bcp.2012.04.00 1">[More Information]</a> 2011 Toh, S., Murray, M., Tan, K., Mulay, V., Grewal, T., Lee, E., Zhou, F. (2011). Functional analysis of pharmacogenetic variants of human organic cation/carnitine transporter 2 (hOCTN2) identified in Singaporean populations. Biochemical Pharmacology, 82(11), 1692-1699. <a href="http://dx.doi.org/10.1016/j.bcp.2011.08.00 8">[More Information]</a> Zhou, F., Lee, A., Krafczyk, K., Zhu, L., Murray, M. (2011). Protein Kinase C Regulates the Internalization and Function of the Human Organic Anion Transporting Polypeptide 1A2. British Journal of Pharmacology, 162(6), 1380-1388. <a href="http://dx.doi.org/10.1111/j.1476-5381.201 0.01144.x">[More Information]</a> 2010 Zhou, F., Zhu, L., Cui, P., Church, W., Murray, M. (2010). Functional characterization of nonsynonymous single nucleotide polymorphisms in the human organic anion transporter 4 (hOAT4). British Journal of Pharmacology, 159, 419-427. <a href="http://dx.doi.org/10.1111/j.1476-5381.200 9.00545.x">[More Information]</a> Cui, P., Lee, A., Zhou, F., Murray, M. (2010). Impaired transactivation of the human CYP2J2 arachidonic acid epoxygenase gene in HepG2 cells subjected to nitrative stress. British Journal of Pharmacology, 159(7), 1440-1449. <a href="http://dx.doi.org/10.1111/j.1476-5381.200 9.00628.x">[More Information]</a> Murray, M., Cui, P., Zhou, F. (2010). Roles of Mitogen-Activated Protein Kinases in the Regulation of CYP Genes. Current Drug Metabolism, 11(10), 850-858. <a href="http://dx.doi.org/10.2174/1389200107944 79664">[More Information]</a> 2008 Zhou, F., Xu, W., Tanaka, K., You, G. (2008). Comparison of the Interaction of Human Organic Anion Transporter hOAT4 with PDZ Proteins between Kidney Cells and Placental Cells. Pharmaceutical Research, 25(2), 475-480. <a href="http://dx.doi.org/10.1007/s11095-007-935 Publications for Fanfan Zhou 9-4">[More Information]</a> 2007 Role of glycosylation in the organic anion transporter OAT1. Journal of Biological Chemistry, 279(15), 14961-14966. Zhou, F., You, G. (2007). Molecular Insights into the Structure-Function Relationship of Organic Anion Transporters OATs. Pharmaceutical Research, 24(1), 28-36. <a href="http://dx.doi.org/10.1007/s11095-006-914 4-9">[More Information]</a> Zhou, F., Tanaka, K., Pan, Z., Ma, J., You, G. (2004). The role of glycine residues in the function of human organic anion transporter 4. Molecular Pharmacology, 65(5), 1141-1147. Zhou, F., Hong, M., You, G. (2007). Regulation of human organic anion transporter 4 by progesterone and protein kinase C in human placental BeWo cells. American Journal of Physiology: Endocrinology and Metabolism, 293, E57-E61. Zhou, F., Tanaka, K., Soares, M., You, G. (2003). Characterization of an organic anion transport system in a placental cell line. American Journal of Physiology: Endocrinology and Metabolism, 285(5), E1103-E1109. Hong, M., Zhou, F., Lee, K., You, G. (2007). The putative transmembrane segment 7 of human organic anion transporter hOAT1 dictates transporter substrate binding and stability. Journal of Pharmacology and Experimental Therapeutics, 320(3), 1209-1215. 2006 Zhou, F., Illsley, N., You, G. (2006). Functional characterization of a human organic anion transporter hOAT4 in placental BeWo cells. European Journal of Pharmaceutical Sciences, 27(5), 518-523. <a href="http://dx.doi.org/10.1016/j.ejps.2005.09.00 8">[More Information]</a> 2005 Hong, M., Xu, W., Yoshida, T., Tanaka, K., Wolf, D., Zhou, F., Inouye, M., You, G. (2005). Human organic anion transporter hOAT1 forms homooligomers. Journal of Biological Chemistry, 280(37), 32285-32290. Zhou, F., Xu, W., Hong, M., Pan, Z., Sinko, P., Ma, J., You, G. (2005). The role of N-linked glycosylation in protein folding, membrane targeting, and substrate binding of human organic anion transporter hOAT4. Molecular Pharmacology, 67(3), 868-876. 2004 Hong, M., Zhou, F., You, G. (2004). Critical amino acid residues in transmembrane domain 1 of the human organic anion transporter hOAT1. Journal of Biological Chemistry, 279(30), 31478-31482. Tanaka, K., Zhou, F., Kuze, K., You, G. (2004). Cysteine residues in the organic anion transporter mOAT1. Biochemical Journal, 380(1), 283-287. Zhou, F., Pan, Z., Ma, J., You, G. (2004). Mutational analysis of histidine residues in human organic anion transporter 4 (hOAT4). Biochemical Journal, 384(1), 87-92. Tanaka, K., Xu, W., Zhou, F., You, G. (2004). 2003