ABSTRACT River Asa was chosen as a case study because it is about the longest river in Ilorin. It supplies the bulk of water used by people in Ilorin and its environs for different activities depending on the point of contact. In this study, water samples were taken at eight different points along the Asa River during the dry and wet seasons for analysis. These were at Asa dam, Asa dam Road bridge, between Asa Road bridge and Unity Road bridge, Unity Road bridge, between Emir’s Road bridge and unity road bridge, Emir’s Road brigde, between Amilegbe bridge and Emir’s Road brigde and Amilegbe road bridge. The data obtained from laboratory analysis were compared with World health Organisation’s standard values for the various parameters tested. Variation of pollution of the river in dry and raining season was determined and a profile of each parameter was created for both dry and wet season. Mathematical equations were also derived to describe the variation of each parameter. The result shows that BOD, COD, Chloride, Sulphate and pH values are higher during the wet season than during dry season except for TDS which varies at different points and conductivity which has higher values during dry season. This indicates that the volume of waste discharged into the water course was already over taxing its capacity for self purification. Asa River is polluted.