Genetics Meiosis Sexual Life Cycles Alternation of meiosis and fertilization is common in most living organisms Sexual Life Cycles of Humans Meiosis diploid and haploid stages n n Meiosis II n 2n Meiosis I diploid n n haploid Meiosis II n haploid Meiosis I reduction division, separates homologues n n Meiosis II n 2n Meiosis I diploid n n haploid Meiosis II n haploid Meiosis I Interphase (precedes Meiosis) Meiosis I G1 , S, G2 prophase I, metaphase I, anaphase I, telophase I Cytokinesis (follows Meiosis) Interphase precedes meiosis G1 first gap S synthesis G2 second gap Prophase I longest phase synapses tetrad formation crossing-over chiasma Metaphase I tetrads align at the metaphase plate Anaphase I homologous chromosomes pull apart separation accomplished by disassembly of kinetochore microtubules elongation by nonkinetochore microtubules homologous chromosomes separate Telophase I Chromosomes reach the poles each pole with haploid number cleavage furrow Cytokinesis Division of cytoplasm animal cells form a cleavage furrow plant cells form a cell plate cleavage furrow Meiosis II mitotic division, separates sister chromatid n n Meiosis II n 2n Meiosis I diploid n n haploid Meiosis II n haploid Meiosis II prophase II, metaphase II, anaphase II, telophase II Cytokinesis Prophase II spindle apparatus forms Metaphase II sister chromatids align at equator Anaphase II sister chromatids separate Telophase II daughter cells contain half the number of chromosomes the initial parent cell had 2n diploid n haploid vb v Summary ghgnfn Gametogenesis Spermatogenesis Oogenesis Spermatogenesis Oogenesis End product is ONE egg and 3 polar bodies Some Zygote Possibilities single birth monozygotic (identical) twins 1 sperm + 1 ovum = 1 zygote 1 sperm + 1 ovum = 1 zygote dizygotic (fraternal) twins 2 sperm + 2 ova = 2 zygotes Events that contribute to Variations independent assortment chromosomes random fusion of gametes crossing-over mutations Independent assortment of chromosomes Random fusion of gametes A gamete from one individual unites with a gamete from another individual 1 in 8 million x 1 in 8 million = 64 trillion 64 trillion combinations of chromosomes Crossing-over Prophase I Chromosomes human = 46 chromosomes (23 pairs) autosomal chromosomes = 44 (22 pairs) sex chromosomes = 2 (1 pair) Female Sex Chromosomes female = XX all gametes carry X chromosome homogametic sex Male Sex Chromosomes male = XY 1/2 of gametes carry X, 1/2 carry Y heterogametic sex Hemizygous Activity Is this cell going through mitosis or meiosis? How do you know? Is this cell going through mitosis or meiosis? How do you know? What specific stage is it in? What special process is going on? What is the importance of it? The End