DNA: the molecule of Life ____________ ______________research was used in the discovery of DNA structure ____________ & _______________ developed the first model of DNA Watson & Crick concluded that all living cells contain DNA In prokaryotic cells, where is the DNA located? _______________________________ In Eukaryotic cells, where is the DNA located? ________________________________ ______________ – DNA tightly wrapped around proteins (histones) ________________ supercoils to form chromosome Chromosome are visible during_____________ Chromosomes are found inside the ____________ Chromosomes contain genes and genes are made up of _____________ The genetic material (DNA) determines how an organism develops. How? The ___________________ (nitrogen bases) determine the________ of an organism. DNA’s two main functions are to . . . Store and maintain _____________________________________ information. Provide the instructions for building _______________________________. DNA stands for a.) Deoxyribonucleic acid b.) Directnucleic amino sequence c.) Deoxisis Nitrate Acid DNA is a ______________ - like a twisted rubber ladder made from three main components (like legos) • Sides of the ladder are composed of alternating __________and ____________pieces • Each “rung” of the ladder is made up of two complementary ___________ – A complements ______ – C complements ______ • DNA is put together in chunks called __________________ – Each nucleotide has a sugar, PO43- and base ______________= The copying of DNA prior to the cell undergoing division DNA strands are ___________________- that is each strand can be used to make the other strand. DNA ___________ comes on the scene binds and • ___________ the DNA upstream • ____________ the hydrogen bonds between the base pairs. • This site is known as the __________________________ DNA single-stranded binding proteins stabilize the single strand structure. The sites on DNA where separation and replication occur are called _________________. Replication takes place in both directions until each chromosomes is completely copied. In a ____________ direction. There are two replicating strands the __________ strand and the __________ strand. The leading strand moves in a forward motion. The lagging strand move in a backwards motion. • _______________________ joins individual nucleotides to produce a DNA molecule, which is a polymer. • Complementary Bases begin adding into both sides of the double strand of DNA • A binds with _______, C binds with _______ (no other possibility because of the shape of the bases!) • The final job of the Polymerase is to ____________the sequence of nucleotides after they are added (back on the 5’ end) and to clip out any that are incorrectly paired nucleotides. Finally you have 2 ______________________ of double stranded DNA • The original strand serves as a _______________ for the new strand • The resulting DNA molecules are made up of one ___________(original) strand and one_____________ (new) strand