The Nervous System Neurons: specialized cells of the nervous system. 3 major regions: – 1) Dendrites: receive signals from other neurons – 2) Cell Body: contains the nucleus and organelles – 3) Axon: Carries impulse signal to other neurons/muscles – 4) Myelin sheeth – surrounds portions of the axon to protect and insulate. Types of neurons: Sensory: Send impulses from receptors in the sense organs to the spinal cord and brain. Motor: Carry a signal from brain and spinal cord to glands/muscles. Interneuron: Found in the spinal cord and brain. Sends messages between sensory and motor neurons. Reflex arc A reflex is an preprogrammed response to a certain stimulus. In a reflex a sensory neuron sends a message to the spinal cord which immediately relays a response to a motor neuron. The brain does not interpret the response until after it has happened! Nerve Impulse – charge traveling through a neuron. 1. A stimulus is received by a sensory neuron. 2. The impulse is sent towards the spinal cord and then up to the brain to receive the message. 3. The brain sends a response to a motor neuron with reaction instructions. Action-Potential Nerves: All or nothing! In order for nerves to send an impulse, they rely upon the concentration of ions to function properly. Specifically Sodium and Potassium ions control impulses. At rest: Slightly negative inside the cell, slightly positive outside. Stimulus causes pumps to activate, dumping positive sodium ions outside the cell and pulling in less potassium – reversing the charges on either side of the membrane. Sodium-Potassium Pumps To allow for action potentials, a protein pump is used. The one protein dumps 3 positive charges out of the cell (Na+) and pulls in 2 K+ ions. Each time the pump makes this switch, ATP is used. Impulses The impulse travels the length of the nerve cell’s axon until it reaches the end. Between 2 neurons there is a gap called a synapse. The impulse causes the axon to send neurotransmitters to the dendrites of the next neuron to continue the message. Organization of the Nervous System: 2 Divisions The nervous system has 2 divisions: Central Nervous System (CNS) – – Brain and spinal cord Mostly interneurons Peripheral Nervous System (PNS) – Sensory and motor neurons that carry info to and from CNS. CNS - Brain Cerebrum: Largest portion. – Cerebellum: Found in the back. – Involved with learning, memory, speech/language, senses and voluntary movement. Controls balance and coordination, smooth muscle (involuntary movement). Medulla Oblongata: Relays signals between brain and spinal cord. – Controls breathing rate, heart rate, and blood pressure. CNS – Spinal Cord Extends from the brain to the lower back Protected by the spinal column or vertebrae. Reflexes are processed by the spinal cord. PNS Subdivided into Somatic and Autonomic. Somatic Nervous System relay info from sensors to CNS. – comprises voluntary actions Autonomic carries impulses from CNS to heart and other internal organs. – Comprise involuntary actions (out of your control). Autonomic Divisions Sympathetic and Parasympathetic divisions. – – – Sympathetic Nervous System act in times of stress: High heart rate and breathing. Parasympathetic Nervous System active when the body is relaxed. Both relay messages to the same organs, but the over responses depends on which division is in control. Drug Effects A drug is a substance that alters some function of the body. Certain drugs: – – – change the amount of neurotransmitters released. Block receptors of neurotransmitters. Imitate neurotransmitters. Types of drugs: – Stimulants: Increase activity – Caffine Nicotine Depressants: Decrease CNS, blood pressure and heart rate. Often raise levels of dopamine creating a happy feelings. Alcohol Inhalants Illegal drugs Disorders Meningitis – and inflammation of the meninges. This can be life threatening and lead to a number of other disorders if not treated. Multiple Sclerosis – Breakdown of the myelin protective coverings around neurons. Can cause paralysis, loss of function, cognitive issues and death if untreated.