LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 M.Sc. DEGREE EXAMINATION - ZOOLOGY THIRD SEMESTER – November 2008 GA 25 ZO 3952 - IMMUNOLOGY Date : 07-11-08 Time : 9:00 - 12:00 Dept. No. Max. : 100 Marks PART - A Answer ALL the questions 10 x 2 = 20 Marks 1. Expand and explain PEG 2. Differentiate passive immunity from active immunity. 3. What are vaccines? 4. What is the significance of macrophages? 5. What are mast cells? 6. Comment on heptens 7. What is immune response? 8. Differentiate monoclonal antibody from polyclonal antibody? 9. Explain allergy 10. What are natural killer cells? PART – B Answer any FOUR of the following 4 x 10 = 40 Marks 11. Write notes on vaccines and their schedule intervals. 12. What are antigenic determinants on immunoglobulins. 13. Write notes on different lymphoid organs in man. 14. Explain stem cell development. 15. How is monoclonal antibodies produced. 16. Differentiate B lymphocytes from T lymphocytes PART – C Answer any TWO of the following 2 x 20 = 40 Marks 17. Write an essay on primary and secondary immune deficiency in man. 18. Write an essay on fungal and bacterial infection and immunity of man. 19. Discuss in detail the categories of immunoglobulins. 20. Elaborate the different hypersensitive reactions? ************** 1