LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 M.Sc. DEGREE EXAMINATION – ZOOLOGY THIRD SEMESTER – NOV 2006 AE 22 BT 3901 - MEDICAL MICROBIOLOGY Date & Time : 03-11-2006/9.00-12.00 Dept. No. Max. : 100 Marks Section-A (20 marks) I. Choose the correct answer : (5x1=5 marks) 01. Statement A : Disinfection kills all forms of microbial life Statement B : It is mainly used on inanimate objects a. Statement A is correct, but Statement B is incorrect b. Statement A is incorrect, but Statement B is correct c. Both A and B are correct d. Both A and B are incorrect 02. Pick out the antifungal antibiotic from the following : a. Sulfonamide b. Penicillin c. Streptomycin d. Nystatin 03. Which of the following is associated with complement fixation? a. Hemolysin b. Precipitin c. agglutinin d. Tetanolysin 04. Match A. Pseudomembrane B. Orthomyxovirus C. Chancre D. Trophozoite with i. Influenza ii. Amoebiasis iii. Syphilis iv. Diphtheria a. A - iv, B - i, C - ii, D - iii b. A - iv, B - i, C - iii, D - ii c. A - iv, B - iii, C - i, D - ii d. A - iv, B - ii, C- iii, D - i 05. Typhus fever is caused by : a. Salmonella b. Shigella c. Clostridium d. Rickettsia II. State whether the following statements are True or False. If False give reason : (5x1=5 marks) 06. Cold sterilization refers to the sterilization of biological materials using low temperature. 07. Resident intestinal flora helps in the synthesis of vitamin K. 08. Interferon is a specific antibacterial protein. 09. Mycobacteria are slow growing acid fast bacteria. 10. Dermatophytosis are fungal infections of skin. III. Complete the following. (5x1=5 marks) 11. Jenner is considered as the Father of __________ while ________ is called Father of antiseptic surgery. 12. Communicability is otherwise known as ________ of _________ . 13. The mode of action of sulfonamides is said to be __________ _________ . 14. Histoplosmosis is caused by ______________ _____________ . 15. Anthrax, in man, is called ___________ _____________ . IV. Answer the following, each within 50 words only. (5x1=5 marks) 16. What is Credes method? 17. Distinguish between chronic and latent disease. 18. What role does inflammation play in immunity? 19. Write down the classical strains of Vibrio cholerae. 20. Mention any two species of Plasmodium and the type of malaria caused by them. Section-B Answer any FIVE of the following, each within 200 words only. (5x8=40 marks) 21. Expand each of the following with a footnote each : i. HEPA ii. NMF iii. CFT iv. SIDS v. VZV vi. BCG vii. CNS viii. HTLV 22. Classify bacteria based on Gramstaining reaction. 23. What are the factors which influence infection? Write about any two of them. 24. Give an outline of immunity. Distinguish between absolute and relative immunity. 25. Write about the antigens, symptoms, lab. diagnosis and treatment of influenza. 26. Discuss the symptoms and therapy of AIDS. 27. Distinguish between i. Bactericidal and bacteriostatic agent ii. Transient and resident flora iii. Eosinophils and neutrophies iv. Hepatitis A and B 28. Define the following: i. Oligodynamic action ii. Fumigation iii. Phagocytosis iv. Impetigo Section-C Answer the following each within 1500 words. (2x20=40 marks) 29. a. Give an account of chemical control of microbes. or b. Discuss the causal organism, symptoms, lab. diagnosis and treatment of syphilis. 30. a. Write about the three antigen-artibody reactions. Add a note or their diagnostic importance. or b. Write notes on. i. Exotoxins ii. Trichomoniasis iii. Meningitis - causal organism iv. Candidiasis - treatment and prevention ----