LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 M.Sc. DEGREE EXAMINATION – BIO TECHNOLOGY FIRST SEMESTER – APRIL 2006 IB 27 BT 1806 - BIOCHEMISTRY Date & Time : 20-04-2006/1.00 – 4.00 P.M. Dept. No. Max. : 100 Marks (2 x 10 = 20) Part - A Answer all questions, each in about 50 words. 1. Define racemization. 2. What are cofactors? 3. Give the role of F1 particle. 4. Define Gibb's free energy. 5. What are ketone bodies? 6. Give the energy value of one ATP molecule. 7. What is meant by β - oxidation? 8. What are porphyrins? 9. Mention the role of glutamate dehydrogenase. 10. What are primary metabolites? Part - B (8 x 5 = 40) Answer any five of the following questions, each within 350 words. 11. Write notes on the properties of amino acids. 12. Give the structure of any 2 nucleotides. 13. Explain the mechanism involved in transport across the membrane. 14. Write the chemical reactions involved in glycolysis. 15. Give an account on the electron transport chain in mitochondria. 16. Compare cyclic and non-cyclic photophosphorylation. 17. Describe the reactions of urea cycle. 18. Explain transamination and reductive amination with suitable examples. Part - C (2 x 20 = 40) Answer any two of the following questions, each with 1200 words only. 19. Write detailed notes on the chemical nature of enzymes. Add note on how are they classified. 20. Explain in detail, the structure of biological membrane. 21. Give detailed notes on the steps of gluconeogenesis. 22. With suitable example, explain the mechanism of action of second messengers. _________