LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 M.Sc. DEGREE EXAMINATION – BIOMEDICAL INSTRUMENTATION FIRST SEMESTER – NOV 2006 AG 03 BI 1802 - HAEMATOLOGY Date & Time : 31-10-2006/1.00-4.00 Dept. No. Max. : 100 Marks SECTION –A Answer all the questions (10 x 2 =20) 1. Define “Heamatocrit”. 2. Distinguish Heinz bodies from Dohle bodies. 3. What is Clot Retraction”? 4. Define “Colour Index”. 5. What will happen if platelet count is increased & decreased? 6. Define Haemostasis? 7. Define the term “Lupus Erthematosus” 8. What is Prothrombin? Give the normal value. 9. Distinguish Burr cells from Smudge cells. 10. Define “Christmas Factor”. SECTION –B Answer any four of the following (4 x 10 =40) 11. Write the principle, procedure, normal value & clinical significance of reticulocyte count. 12. How heamoglobin can be estimated calorimetrically? Write its clinical significance. 13. Write a short note on bleeding disorder of man. 14. Enumerate the mechanism of blood coagulation. 15. Explain the derivatives and iron metabolism of hemoglobin. 16. How will you determinate the Erythrocyte sedimentation rate by westergren’s method. SECTION -C Answer any Two of the following. (2 x 20 x=40) 17. How will you classify anaemia and give the details of the iron, hemolytic, and aplastic anaemia with their laboratory data. 18. Explain the development of the blood cells in the human body. 19. Discuss the diagnosis, clinical feature, mode of infection and the treatment of Plasmodium vivax and trypanosomes as blood parasites. 20. Write notes on a) HDN b) Recalcification time c) Activated partial thromboplastin _______________