Rita Ferreira 18.11.2014 Disclaimer: This is my personal opinion and does not reflect that of Pfizer My career “Licenciatura” (4 year) in Biology - University of Aveiro, Portugal MSc in Biotechnology - De Montfort University, UK 6 month placement at the Immunology Department, Erasmus University, Rotterdam, The Netherlands PhD in Transcription Regulation – Cell Biology Department, Erasmus University, Rotterdam, The Netherlands. Post Doc (1 Year) – Cell Biology Department, Erasmus Medical Centre, Rotterdam, The Netherlands Post Doc (6 years) – Department of Haematology, University of Cambridge, UK Senior Scientist, Pfizer Neusentis, Cambridge UK Why leave academia and go to industry? Limited career opportunities in academia. Post Doc Post Doc forever? Senior Post Doc Rare positions PI Dependent on grants and publications What I want to do: continue to work in the lab One option left: Industry Academia vs Industry – Pros and Cons Academia Industry Academic environment Limited access to conferences and talks Freedom of research Research dependent of portfolio requirements Unrestricted sharing of data Availability of funds for research can be restrictive Publication restrictions due to IP concerns Funds for research not restrictive More structured work – pre set goals and timelines Your results dictates your future work Achievements based on publications Long working hours and weekend work A lot more paperwork and meetings Short term contracts and uncertain future More stable working hours and no weekend Achievement based on accomplishment of pre-set yearly objectives work Permanent positions and job stability Better pay, extra benefits and yearly bonuses. Pfizer Research & Development in Europe Pfizer’s R&D presence in the EU Worldwide R&D Neusentis The Clinical Research Unit in Brussels is Pfizer’s site for Phase 1 studies in Europe Grange Castle has a Biotherapeutics Technologies Team Sandwich’s Pharmaceutical Sciences group supports the mid and late-stage portfolio Rare diseases and Centre for Therapeutic Innovation (London) Pfizer’s Business Units (headquartered in Walton Oaks, UK) also support R&D activities in Europe through clinical trials and external collaborations Source: European Sites Database 5 About Neusentis Launched in April 2011,as the consolidation and development of Pain & Sensory Disorders and the Regenerative Medicine portfolios ~130 people with ~100 lab based scientists Location: UK: 7 miles south of Cambridge. 40,000 square feet of office & lab space US: Durham, North Carolina (former Icagen – specialized in ion channel drug discovery) 1. Pain, Sensory Disorders and Channelopathies 2. Regenerative medicine 3. Expertise in Ion Channels and Solute Transporters http://www.neusentis.com/ How Neusentis operates Early target investigation Pharmacology Genetics Exploratory Bionformatics Each scientist has allocated projects. A lot of collaboration with scientists from other areas. Parts of the work are outsourced. Cell Biology Portfolio-driven investigation Molecular Biology Pharmaceutical Sciences Clinical Pharmac ology PKPD, ADME Clinical Research Drug Safety & Toxicology Electrophysiology Chemistry Project Team In vivo Pharmacology Clinical Statistics Informatics PharmacoMetrics Plate based pharmacology Molecular Biology Cell Biology Human cell platform Ex-vivo biology The day to day life as a senior scientist Working on several projects at the same time. You expected to manage your project independently. Your intellectual input is indispensable for the progression of the project. You may have managerial roles: supervision of students, junior scientists and post-docs Exploratory lab work Project lab work Lab support work Meetings Mentoring Others Career paths in industry The Research Career Ladder Associate Scientist Principal Scientist Senior Associate Scientist Senior Principal Scientist Entry level for PhD Scientist Associate Research Fellow) Senior Scientist Senior Research Fellow Parallel career ladders available for other areas (Development, Managerial, etc). Possibility of forward and lateral career progression. Continuous career development encouraged. How is my performance rated January : Objectives/Goals setting Objectives/Goals for the year written down Achievements based on quarterly deadlines July: Mid Year review Objectives/Goals reviewed and adjusted as required Feedback obtained from relevant co-workers December: End of Year Review Objectives/Goals reviewed Feedback obtained from relevant co-workers Performance rated Impact of bonus calculation and pay rise for next financial year Career progression Career development career development plan set up when starting job. What you want to achieve? What you need to do? What your manager can do to facilitate it? Career development plan reviewed every year. Promotion Requires nomination from your manager. All nominations reviewed every 6 month by committee Transition from academia to industry 1 year searching for a position 2 interviews; no response for most of my applications (not even an automated email!) 1 offer (almost 2 month after my first interview) Interviews for industry positions: 1. Phone interview 2. Face to face interview My advice: Apply for jobs that are relevant to your skills. Tailor you CV and cover letter for the position you are applying for. Write you CV in a clear way, with the most important information easy to see. Include you publication in your CV and highlight the transferable skills relevant for the job you are applying for. Don’t get desperate if you don’t receive a timely response after each of the interviews. The process takes much longer than in academia.