UNIVERSITY OF DUBLIN TRINITY COLLEGE DUBLIN INSTITUTE OF MOLECULAR MEDICINE THE EMERGENCY BOOK A supplement to the Safety Manual INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 Contents 1. EMERGENCY PHONE NUMBERS 3 2. FIRE 4 3. INSTITUTE FLOOR PLANS 7 4. FIRST AID 10 5. CHEMICAL 13 6. BIOHAZARD 16 7. RADIATION 18 8. ELECTRICAL 26 9. INTRUDER 26 INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 2 EMERGENCY PHONE NUMBERS Front Gate (Access to all Emergency Services or assistance after normal working hours) 6081999 (external) or internal ext. 1999 Gardai Pearse St. Garda: Kilmainham Garda: Crumlin Garda: 01-6669000 01-6669700 01-6666200 Front Desk Trinity Centre: Ext 2147 from Trinity Line or 01-6082147 from any other St James Fire Alert: 66-2100 from a Trinity Line or 01-4162100 from any other St James Security: 66-2107 from a Trinity Line or 01-4162107 from any other (after hours: 66-2059 or 01-4542059) St James Internal Ambulance/Cardiac Arrest: 66-2222 (from a Trinity Line) Plumbing, Gas or Electrical Faults: Ext 1828 Ext 1999 (Outside office hours: Front gate) College Safety Officer: Mr T Merriman 1914 Radiological Protection: Ms E Lee 2887 Hazardous Chemicals: Dr Michael Bridge 1264 Bio-Safety and Genetic Manipulation: Dr R Russell Dr F Falkiner 1194 2137 Bio-Resources: Mr P Nowlan 1008 Laser: Dr Louise Bradley 3595 INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 3 FIRE Familiarise yourself with these procedures now. In a fire you may have to operate in smoke-filled areas If you discover a fire or fire-related emergency such as abnormal heating of material, a flammable gas leak, a flammable liquid spill, smoke, or odor of burning, immediately follow these procedures: 1. Raise the Alarm Activate the building alarm by break-glass alarm or ring Front Desk Trinity Centre at 2147 from a Trinity Line or 01-6082147 from any other. Call “Fire!” to those in vicinity. If Front desk is not immediately available Notify the Fire Brigade by dialing Trinity College Front Gate 1999 from a Trinity Line, or 016081999 from any other Or St James Fire Alert at 66-2100 from a Trinity Line or 01-4162100 from any other (St James security: 66-2107 from a Trinity Line or 01-4162107 from any other. After hours: 662059 or 01-4162059) 2. Tackle the Fire If you are trained in Fire Fighting and the use of Fire Extinguishers: Isolate the area by closing windows and doors and evacuate the room Shut down equipment in the immediate area, if possible Use a portable fire extinguisher/fire blanket to: assist yourself to evacuate; assist another to evacuate; and control a small fire, if possible Provide the fire/police with the details of the problem upon their arrival. Special hazard information you might know is essential for the safety of the emergency responders 3. Evacuate the Building If the fire alarms are ringing, you must evacuate the building and stay out until notified to return Walk quickly to the nearest exit Obey instructions of the Fire Wardens Close all Fire Doors Do not use lifts INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 4 4. Assemble away from the Fire (At 1 of the 3 Designated Assemble Points) Exiting Main Entrance - Assemble at Trinity Centre Car Park beyond wooden fence Exiting from Old Main Entrance of Trinity Centre - Assemble at adjacent car park opposite Hospital 2 Exiting from Service Entrance of Trinity Centre - Assemble at Luas Stop Do not leave these areas as all persons must be accounted for! Do you know where your exits are? Consult the enclosed floor plans of the Institute of Molecular Medicine and identify your exits from the building Basement: there are two exits, one at the main stairs leading to the main entrance of the Trinity Centre, the other at the stairs facing James St. In the event of a fire in another part of Trinity Centre, use the latter exit. Ground Floor: there are three exits, one leading to main entrance of the Trinity Centre, one at the stairs opposite Kenny’s Pub, the other at the milling area where the food and drink dispensing machines are located. Use the latter two in preference. First Floor: there are two exits, one at the main stairs leading to the main entrance of the Trinity Centre, the other at the stairs opposite Kenny’s Pub. In the event of a fire in another part of Trinity Centre, use the latter exit. Do you know where the break-glass alarms are situated in your vicinity? There are at least two on each floor. Break glass with either a suitable implement or your cloth-covered elbow. Do you know where the fire extinguishers are situated? There are numerous Fire Points throughout the Institute consisting of pairs of extinguishers, one of which is usually CO2 -based. Do you know how to use a fire extinguisher? If you have not received fire-fighting instructions, read the label on the extinguisher now. Do you know which type of fire extinguisher to use on a particular fire? TYPE Class A Solid Material Water YES Dry Powder YES Class B Flammable Liquids Class C Gases Class D Burning Metals YES YES YES YES YES Foam YES Carbon Dioxide YES INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 5 IF YOU FIND A FIRE DOOR HELD OPEN (e.g. BY A WEDGE OR FIRE EXTINGUISHER), OR FAILING TO CLOSE OWING TO A JAMMING HINGE CLOSE IT! THESE DOORS SAVE LIVES, BUT ONLY WHEN CLOSED. IGNORING OPEN FIRE DOORS IS HIGHLY IRRESPONSIBLE. It is an offence to tamper with Fire Fighting equipment or to disregard the Fire Emergency Procedure INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 6 INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 7 INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 8 INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 9 EMERGENCY FIRST AID Intended for initial treatment only. Medical attention should be sought for all but the most minor injuries. Small Cuts and Grazes a) b) c) d) Open an antiseptic wipe and gently clean away any dirt or grit, or wash with lots of water and soap Gently dry with a fresh piece of surgical wool Apply a First Aid dressing or, if the wound is larger, a piece of lint held by a bandage Seek medical advice if there is any possibility of infection by CI tetani, HIV or Hepatitis viruses and report to the Accident & Emergency Department immediately Needle-stick Injury a) b) c) d) e) Make the wound bleed Wash with running water and wipe with an alcohol swab Cover with a waterproof dressing Report the accident to the Safety Officer Seek medical advice if there is any possibility of infection by HIV or a hepatitis virus and report to the Accident & Emergency Department Bruising a) b) c) Before treatment, check there are no further injuries present Put the bruised part at rest in the most comfortable position Apply a cold compress to reduce the swelling and to relieve pain To make a cold compress: Soak a thin towel/large handkerchief/piece of flannel/absorbent cotton wool in cold water. Squeeze out surplus water and apply the compress to the bruised area. Keep it cool by dripping water on it as required or replace it by further compresses. Ensure good evaporation by not covering the compress. If necessary, use open weave material to keep it in place. Bleeding a) b) c) d) The aim of treatment is to stop bleeding and prevent infection Do not attempt to remove scabs or clots. Avoid the use of a tourniquet that, although stopping the bleeding, may also lead to damage due to lack of circulation Application of a firm dressing to the bleeding point will usually stop the bleeding Where possible, raise the bleeding point above the level of the heart Eye Injuries Foreign bodies a) Foreign bodies such as eyelashes or particles of grit may enter the eye and rest either on the exposed surface or under the eyelids. They may cause irritation, pain, redness and watering b) Do not rub the eye. The tears induced by the foreign body may wash the particle out. A similar effect may be achieved by splashing water into the eye INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 10 c) d) e) f) If the foreign body can be seen on the surface it may be lifted out with the corner of a handkerchief or tissue Moving the eye in various directions and gently lifting the upper eyelid over the lower lid may reveal a hidden foreign body which may then be washed out or lifted out with a handkerchief If the foreign body is on the coloured part of the eye (iris or pupil) or if it is stuck to the surface there may be damage to areas critical to sight so immediate medical advice should be sought. Repeat, do not rub the eye! An eye pad or cotton wool pad taped over the closed eye helps to rest the eye and may relieve discomfort on the way to the Accident and Emergency Department Chemical a) Irrigate the eyeball and inner surface of eyelid with plenty of cool water for at least 15 minutes. Forcibly hold eyelids open to ensure effective wash b) Check for and remove contact lenses c) Get medical attention promptly Burns Burns may be caused by hot liquids or solids, by liquid and solid chemicals, electricity and fire. For minor burns (first or second degree), hold the affected area under cold water for at least 15 minutes. If the burn occurred through clothing, remove this first. Wash with cold water and dry gently. Intact blisters are usually left alone unless they are causing pain due to tension. Apply antiseptic cream and cover with a dressing. Change the dressing twice a week. In the case of serious burns (third degree), call for medical assistance. Electric Shock a) b) c) Switch off current - if live wires are exposed use a DRY insulated object to cut off the power supply If shock or serious injury has occurred summon medical aid immediately. Keep the patient comfortable until its arrival. Treat for cardiac or respiratory arrest if necessary Seek medical aid for all electric burns Cardiopulmonary Resuscitation If a person collapses or is found unconscious: a) Call for help b) If breathing or heart beat have stopped Call the hospital cardiac arrest team Summon medical help from within the laboratory Begin cardiopulmonary resuscitation Artificial Respiration (The Kiss of Life) a) Lay the patient face-up, loosen all tight clothing and make certain that the mouth and throat are not blocked by the tongue, loose food particles, dentures or even broken teeth INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 11 b) Now tilt the head right back: this straightens the windpipe and thus helps breathing. Place one hand over the forehead and the other on the chin. Gently pull up the jaw and blow into the patient's mouth - KEEPING THE NOSE OCCLUDED c) Alternatively, if blowing into the nostrils, keep the patient's mouth tightly closed. Resuscitation should be interrupted to allow the patient to exhale. Continue this 10-15 times per minute – BEWARE!, if the patient shows signs of vomiting or gagging, turn the head and body to one side and KEEP ALL AIR PASSAGES UNBLOCKED Cardiac Massage a) b) c) d) e) Place yourself at the side of the patient Feel for the lower half of the breastbone Place the heel of your hand on this part of the bone keeping palm and fingers off the chest Cover this hand with the heel of the other hand With arms straight, rock forwards pressing down on the lower half of the breastbone (in an unconscious adult, it can be pressed towards the spine for about 4 cm). Repeat the pressure 80-100 times a minute NEVER GIVE UP HOPE. CONTINUE THE KISS OF LIFE AND CARDIAC MASSAGE UNTIL THE VICTIM’S NATURAL BREATHING RHYTHM AND PULSE ARE STRONG AGAIN or UNTIL MEDICAL ASSISTANCE ARRIVES INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 12 CHEMICAL Cleaning Up Chemical Spills Try to anticipate the types of chemical spills that can occur in your laboratory and obtain the necessary equipment (spill kits and personal protective equipment) to respond to a minor spill. Learn how to clean up minor spills of the chemicals you use regularly, safely Familiarise yourself with the Chemical Spill Kits near you Familiarise yourself with the MSDS for chemicals used in your laboratory Minor Chemical Spill a) b) c) d) e) f) g) Alert people in immediate area of spill Increase ventilation in area of spill (open windows, turn on hoods) Wear personal protective equipment, including safety goggles, gloves and long-sleeve lab coat Avoid breathing vapors from spill Use appropriate kit to neutralize and absorb inorganic acids and bases. Collect residue, place in container, and dispose as hazardous chemical waste For other chemicals, use appropriate kit or absorb spill with vermiculite, dry sand, diatomaceous earth or paper towels. Collect residue, place in container, and dispose as chemical waste Clean spill area with water Major Chemical Spill a) b) c) d) e) f) Attend to injured or contaminated persons and remove them from exposure Alert people in the laboratory to evacuate If spilled material is flammable, turn off ignition and heat sources. Place other device (plastic bag) over spilled material to keep substance from volatilizing Call Emergency Number Close doors to affected area Have a person with knowledge of the incident and laboratory available to answer questions from responding emergency personnel Mercury Spills a) b) c) Use a vacuum line with an in-line dry trap attached to a tapered glass tube similar to a medicine dropper to pick up mercury droplets Cover small droplets in inaccessible areas with one of the following: Powdered sulfur Powdered zinc Place residue in a labeled container and dispose of as hazardous chemical waste Alkali Metal Spills Smother with powdered graphite, sodium carbonate, or calcium carbonate. INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 13 Personal Contamination and Injury 1. General Information a) b) c) d) e) f) Know the locations of the nearest safety shower Report all incidents and injuries to your supervisor If an individual is contaminated or exposed to a hazardous material in your laboratory, do what is necessary to protect their life and health as well as your own. Determine what the individual was exposed to. The MSDS will contain special first aid information Do not move an injured person unless they are in further danger (from inhalation or skin exposure) A blanket should be used immediately to protect the victim from shock and exposure Get medical attention promptly by dialing 2. Chemical Spills on the Body a) b) c) d) Quickly remove all contaminated clothing and footwear Immediately flood the affected body area with cold water for at least 15 minutes. Remove jewellery to facilitate removal of any residual material Wash off chemical with water only. Do not use neutralizing chemicals, unguents, creams, lotions or salves Get medical attention promptly It should be noted that some chemicals (phenol, aniline,) are rapidly adsorbed through the skin. If a large enough area of skin is contaminated, an adverse health effect (systemic toxicological reaction) may occur immediately to several hours after initial exposure depending on the chemical. If more than 9 square inches of skin area has been exposed to a hazardous chemical, seek medical attention after washing the material off the skin. If the incident involves hydrofluoric acid (HF), seek immediate medical attention. Provide the physician with the chemical name. 3. Chemical Splash in the Eye a) b) c) Irrigate the eyeball and inner surface of eyelid with plenty of cool water for at least 15 minutes. Use eyewash or other water source. Forcibly hold eyelids open to ensure effective wash Check for and remove contact lenses Get medical attention promptly 4. Ingestion of Hazardous Chemicals a) b) c) d) e) Identify the chemical ingested First aid measures should be carried out according to MSDS Call for an ambulance Cover the injured person to prevent shock Provide the ambulance crew and physician with the chemical name and any other relevant information. If possible, send the container, MSDS or the label with the victim 5. Inhalation of Smoke, Vapors and Fumes a) Anyone overcome with smoke or chemical vapors or fumes should be removed to uncontaminated air and treated for shock INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 14 b) c) d) Do not enter the area if you expect that a life threatening condition still exists - oxygen depletion, explosive vapors or highly toxic gases (cyanide gas, hydrogen sulfide, nitrogen oxides, carbon monoxide) Follow standard CPR protocols Get medical attention promptly 6. Burning Chemicals on Clothing a) b) c) d) e) Extinguish burning clothing by using the drop-and-roll technique with a fire blanket (see fire blanket cover) Remove contaminated clothing, however, avoid further damage to the burned area. If possible, send the clothing with the victim Remove heat with cool water or ice packs until tissue around burn feels normal to the touch. Do not apply ice directly to the site Cover injured person to prevent shock Get medical attention promptly Actions to be Avoided During Emergencies There are some actions, which must not be taken when handling emergencies. These include: Do not force any liquids into the mouth of an unconscious person Do not handle emergencies alone, especially without notifying someone that the accident has occurred Do not linger at the accident scene if you are not one of the emergency responders INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 15 BIOHAZARD BIOHAZARD SPILL CLEANUP PROCEDURES Depending on the size of the spill, notify everyone in the laboratory and call your biohazard representative If a spill contains Class 2 or higher containment material, or if the spill is considered too large or too dangerous for laboratory personnel to safely clean up, secure the entire laboratory and call Hospital Infection Control immediately for assistance If the spill occurs: 1. Inside the BioSafety Cabinet (BSC) a) b) c) d) e) f) g) h) i) j) k) 2. Wait at least five minutes to allow the BSC to contain aerosols Wear laboratory coat, safety glasses and gloves during cleanup Allow BSC to run during cleanup Apply disinfectant and allow a minimum of 20 minutes contact time Wipe up spillage with disposable disinfectant-soaked paper towels Wipe the walls, work surfaces and any equipment in the cabinet with disinfectant-soaked paper towels Discard contaminated disposable materials using appropriate bio-hazardous waste disposal procedures Place contaminated reusable items in biohazard bags or autoclavable pans with lids or wrap in newspaper before autoclaving Expose non-autoclavable materials to disinfectant (20 minutes contact time) before removal from the BSC Remove protective clothing used during cleanup and place in a biohazard bag for autoclaving Run BSC 10 minutes after cleanup before resuming work or turning BSC off In the Laboratory, Outside the Biosafety Cabinet a) b) c) d) e) Call the Safety Officer if the material is Class 2 or greater Clear area of all personnel. Wait at least 30 minutes for aerosol to settle before entering spill area Remove any contaminated clothing and place in biohazard bag to be autoclaved Put on a disposable gown, safety glasses and gloves Initiate cleanup with disinfectant as follows: Place dry paper towels on spill then layer a second set of disinfectant soaked paper towels over the spill Encircle the spill with additional disinfectant being careful to minimize aerosolization while assuring adequate contact Decontaminate all items within the spill area Allow at least a minimum of 20 minutes contact time to ensure germicidal action of disinfectant Wipe equipment and reusable items with appropriate disinfectant Discard contaminated disposable materials using appropriate bio-hazardous waste disposal procedures INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 16 3. In a Centrifuge a) b) c) d) e) f) 4. Clear area of all personnel Wait 30 minutes for aerosol to settle before attempting to cleanup spill Wear a laboratory coat, safety glasses and gloves during cleanup Remove rotors and buckets to nearest BSC for cleanup Thoroughly disinfect inside of centrifuge Discard contaminated disposable materials using appropriate bio-hazardous waste disposal procedures Outside the Laboratory, In Transit a) b) c) d) e) f) Discard contaminated disposable materials using appropriate bio-hazardous waste disposal procedures To prevent a spill, transport labeled bio-hazardous material in an unbreakable, well-sealed primary container placed inside of a second unbreakable, lidded container (cooler, plastic pan or pail) labeled with the biohazard symbol Should a spill occur in a public area, do not attempt to clean it up without appropriate personal protection equipment Secure the area, keeping all people well clear of the spill Call for assistance in cleanup Stand by during spill response and cleanup activity and provide assistance only as requested or as necessary INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 17 RADIATION The sources of ionising radiation in use in College include sealed sources, unsealed sources and irradiating apparatus. Possible emergencies related to the use of these sources of ionising radiation can be broadly defined in five categories, as follows: A. Fire B. Loss or Theft of a licensed item C. Damage to sealed sources D. Faults in safety systems of irradiating apparatus E. Spills of unsealed sources The following are the emergency procedures to be implemented in the event of each of the above categories of emergency: A. Fire Should a fire occur in a lab/room where sources of ionising radiation (sealed or unsealed) are stored/used, the following procedure should be implemented by the person becoming aware of the fire: 1. Raise the Alarm and Evacuate Raise the fire alarm, by breaking the glass at the nearest break glass unit Ring Front gate security at ext. 1999 internal (01-6081999 external), and advise of the location, and size of the fire, and that there are sources of ionising radiation in the room. If the emergency services need to be contacted such as the fire brigade or ambulance, these should be contacted through the front gate security staff who can open gates for them and direct them into the appropriate area of College etc Attempt to fight the fire with an appropriate fire extinguisher, only if you have been trained in the use of fire extinguishers, if the fire is small and manageable, you have raised the alarm first, and you have a clear escape route. * If possible, before leaving the lab, remove any sources of ionising radiation within their shielded containers from the immediate danger area. * Leave the building immediately by the nearest route, closing doors and windows in the lab if possible before leaving. In general, all lab services, except lighting, but including ventilation, should be switched off and all doors and windows should be closed. However when radioactive gas or vapour, such as tritiated water vapour is to be dispersed, mechanical ventilation should be left on, and with discretion, some windows may be left open Go to your assembly point providing that it is upwind of the building and the fire Stay upwind of the building and the fire after emergency evacuation and direct others to do the same * Please note: Your personal safety is of paramount importance in the event of a fire. Do not attempt to fight the fire, remove materials, or close windows / doors if doing so would endanger your personal safety. 2. Notify the Proper Authorities After retreating to a safe area, you should then: INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 18 Notify the Departmental Radiological Protection Supervisor (DRPS) (Contact details at end of this document) Notify the College Radiological Protection Officer (RPO) (Ph. 6082887) The College Radiological Protection Officer will notify the RPII immediately in the event of an emergency situation, and in particular if the fire is not brought immediately under control, or if there is a risk of exposure of persons to ionising radiation. 3. Sealed/Unsealed: Determine the types and activities involved and likely consequences Where sealed or unsealed sources are involved in a fire, the DRPS should be consulted to determine from the departmental inventory the quantities, activities and types of sources that are stored/used in that room, and from this information, determine the likely consequences resulting from the fire in terms of possible exposures. Each DRPS should attempt to determine this information for each lab area in their dept. prior to any possible emergency arising, so that this information is readily available in the event of an emergency. This information should be given to any emergency services personnel eg. fire services that attend the incident. 4. X-Ray Machines:Unplug Should a fire occur in a room where irradiating apparatus such as X- Ray Machines are used, the machine should be switched off and unplugged, and the general procedures outlined above with regard to raising the alarm, attempting to extinguish the fire, and evacuating the building will also apply thereafter. Before reusing any irradiating apparatus after a fire in a room accommodating it (if indeed it is still operational), it should be subject to a full examination by a competent person including testing of safety systems, interlocks etc. B. Loss or Theft (of any licensed item, i.e. sealed or unsealed sources or irradiating equipment) 1. Notify the Proper Authorities Notify the Departmental Radiological Protection Supervisor (DRPS) (Contact details at end of this document) Notify the Departmental Radiological Protection Supervisor (DRPS) (Contact details at end of this document) Notify the College Radiological Protection Officer (RPO) (Ph. 6082887) Notify the RPII (Contact details at end of this document) The normal procedure should be that the person becoming aware of the loss/theft of the item should notify the DRPS, the DRPS should notify the RPO, and the RPO should notify the RPII. 2. Provide Relevant Information Give details of the ionising radiation source, its form (sealed, unsealed, irradiating apparatus), and details of the quantity, activity and concentration where relevant Provide as much detail as possible about the circumstances leading to the loss or theft of the item Provide details regarding labelling or packaging of the item, as this will be of relevance if the source is found by or comes into contact with a member of the public. For instance, does it have a radiation trefoil sign, or a Transport Index indicating that it could be hazardous to be in close proximity to the original container? INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 19 3. Search for Lost Items Undertake an immediate search for the source if it is thought to be lost While the search is underway, there should be no sweeping of floors, no removal of waste, and no disturbing of furniture etc Examine all relevant records, storage inventories and usage records, speaking to all users, regarding when the material was used last, where it was stored etc If there is any reason to suspect that a lost source might have become damaged, the possibility of contamination by spilled radioactive substance should be borne in mind, and procedure with regard to spillages and decontamination as outlined under section E below, may need to be applied 4. Notify Gardai if Theft is Suspected Notify the Gardai immediately if theft is suspected, and give as much information as possible regarding the nature of the radioactive material and the circumstances leading to the suspected theft. The greatest danger with loss or theft of radioactive materials is the hazard presented to someone who comes into contact with radioactive materials and is unaware of the hazard. It is imperative therefore that action is taken immediately it is suspected that radioactive materials are missing. It would be unacceptable to wait days or weeks hoping that the missing materials will ‘turn up’. C. Damage to Sealed Sources 1. Discontinue use of Damaged Source Immediately All sealed sources in College are subject to routine leak tests at least once every 2 years. If sources fail this leak test, they will not be licensed for use in College However sealed sources may become damaged due to for example, overt mechanical damage, chemical corrosion, or use in hostile conditions. It is important therefore that they are stored and used correctly, and in appropriate conditions If a sealed source becomes damaged, there is a risk of contamination with the radioactive material contained in the sealed source Use of the damaged source must discontinue immediately 2. Seek advice and assistance from a competent person The DRPS in the department licensed to use the sealed source may not necessarily have the expertise or equipment such as contamination monitors, decontamination kits, available to him/her to deal with such an event. A DRPS familiar with the use of unsealed sources such as the DRPS for Biochemistry or Genetics for example, should be contacted for advice and assistance, as should the College RPO (Contact details at end of this document) The College RPO and/or available DRPS will assess potential contamination to personnel involved and equipment Procedures with regard to personnel and equipment decontamination as outlined in section E below with regard to spills of unsealed sources will then be applied D. Faults in Safety Systems of Irradiating Apparatus 1. Isolate Equipment, Prevent Use and Report to DRPS and College RPO INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 20 All irradiating apparatus must be routinely and adequately serviced and maintained by a competent person, to ensure that it is in a serviceable condition, and that all safety devices, and interlocks etc. are operational. Irradiating apparatus that is operating incorrectly can be made safe by operating an emergency cut off switch and / or isolating the equipment from the mains supply. Any equipment indicating a fault in a safety system such as an interlock must not be used and must be reported at once to the DRPS who should instigate the necessary repair / service. 2. Investigate Overexposures Any case of overexposure or suspected overexposure must be reported to the DRPS and College RPO for investigation and dosimeters must be sent for analysis immediately. E. Spills of Unsealed Sources Spills can be categorised as Minor or Major Spills. The general priorities in dealing with spills are as follows: Deal with any personal injury or administer any first aid necessary first Alert people in the area to the spill Limit access to the area Take all reasonable precautions to limit the spread of radioactive contamination Confine the movement of people until they have been monitored and found free of contamination Notify the DRPS and CRPO if necessary Initiate clean up and decontamination operations under DRPS supervision 1. Minor Spill (Contamination to a small area and no personnel contamination) Alert people in the lab area that a spill has occurred Limit access to the affected area Put on protective clothing, lab coat, disposable gloves and overshoes Cover a liquid spill with absorbent paper or pads. Place damp towels over spills of dry powder Monitor personnel and remove any contaminated clothing Notify your Departmental Radiological Protection Supervisor (DRPS) (Contact details at end of this document) If DRPS is unavailable, contact the College Radiological Protection Officer (RPO) (Ph. 6082887), or the College Safety Officer / Deputy RPO (Ph.6081914) If outside of working hours, ring front gate security at ext.1999 internal (6081999 external), and ask for radiation safety assistance Deal with personal contamination following the guidelines outlined below Clean and decontaminate relevant surfaces, equipment and clothing as required, following the guidelines outlined below Dispose of all contaminated material as radioactive waste 2. Major Spill (Personnel contaminated or large areas affected) Put on protective clothing, lab coat, disposable gloves and overshoes. Consideration may also need to be given also to wearing of additional PPE such as particle/vapour respirator if volatile radioactive materials, radioactive aerosols, or airborne radioactive dust or gases are involved, and a radiation body-shield, such as a lead apron may be required in some instances etc INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 21 Attend to injured or contaminated persons, (Taking appropriate personal precautions and where appropriate placing any casualties on plastic sheeting to limit spread of contamination) Where possible do not remove contaminated individuals from the contaminated area, to limit the spread of contamination, however where urgent first aid is required or there is a danger of increasing exposure to an individual by remaining in the contaminated area, limiting the spread of contamination should not take precedence over personal health and safety issues, and where necessary, therefore contaminated persons should be removed from the immediate contaminated area to an adjacent safe area within the lab Take all reasonable precautions to limit the spread of radioactive contamination by for example, laying down ‘BenchKote’ or similar sheeting eg. builders’ plastic damp proof membrane, and wearing plastic disposable over-shoes etc Cover a liquid spill with absorbent paper or pads. Place damp towels over spills of dry powder Advise non contaminated persons present to vacate the laboratory, and prevent others from entering the laboratory Monitor persons remaining for contamination Remove contaminated clothing Deal with personal contamination following the guidelines outlined below Confine movement of all potentially contaminated personnel to prevent further spread of contamination Notify your Departmental Radiological Protection Supervisor (DRPS) (Contact details at end of this document). Notify the College Radiological Protection Officer (RPO) (Ph. 6082887), or the College Safety Officer / Deputy RPO (Ph.6081914). Notify front gate security at ext.1999 internal (6081999 external), and advise of the situation. If emergency services such as ambulance services need to be provided, ask front gate to arrange this, and tell them your exact location. If outside of working hours, front gate can contact the College RPO or College Safety Officer Notify the Principal Investigator Make safe any functioning apparatus, turn off ventilation and other services, (except where radioactive gas or vapour, such as tritiated water vapour is to be dispersed) close doors and windows. Lock and seal off room if necessary Restrict access to the contaminated area, by cordoning off the immediate area Identify the radionuclide and estimate the activity, and display this information on a warning sign Measure and note the contamination before and after a decontamination attempt in order to assess its effect, to estimate the radiation dose, and to allow a record to be made of the activity disposed Clean and decontaminate relevant surfaces, equipment and clothing as required, following the guidelines outlined below Dispose of all contaminated material as radioactive waste 3. Cleaning of Spills and Decontamination a) Decontamination of Contaminated Surfaces Restrict access to essential clean up personnel only Put on protective clothing, lab coat, disposable gloves and overshoes. Consideration may also need to be given also to wearing of additional PPE such as particle/vapour respirator if volatile radioactive materials, radioactive aerosols, or airborne radioactive dust or gases are involved, and a radiation body-shield, such as a lead apron may be required in some instances etc INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 22 b) Cover a liquid spill with absorbent paper, tissues, or pads. Place damp towels over spills of dry powder Mop up the spill with the absorbent paper towards the centre Seal contaminated items in a plastic bag for disposal or cleaning. (do not try to decontaminate disposable items) Monitor the affected surface, if contamination is excessive, then wash the surface with a decontaminating agent, such as ‘Decon’, ‘Count Off’, ‘Lipsol’ etc Mop up the washing fluid with disposable towels, and seal the towels in a plastic bag for subsequent disposal Monitor the surface If contamination is persistent, repeat the above washing procedure If repeated washing is not effective, remove the surface if possible, store it in an appropriate secure area eg. radioactive waste store, and allow the contamination to decay, or where this is not possible / feasible, cover the surface with a plastic sheet, and perspex board (for Betas), restrict access and allow activity to decay. Decontamination of Equipment If equipment is contaminated, the same general clean up rules as outlined above will apply, however care should be taken not to use a decontaminating agent that will attack the material from which the equipment is made. Equipment may need to be dismantled and individual parts decontaminated. If persistent, take the equipment out of use, store in an appropriate secure area eg. radioactive waste store, and allow activity to decay if half life permits, otherwise treat as radioactive waste and arrange for long term storage or disposal if possible. c) Decontamination of Clothing Wear disposable gloves Remove clothing taking care to minimise the spread of contamination to the body and the environment Monitor activity on the clothes Do not wash clothes if the activity present exceeds the liquid waste disposal limits as outlined in SI125 of 2000. In this case the clothes should be stored in a suitable secure storage container, and must be stored until ‘delay and decay’ allows for compliance with these limits Once activity limits can be complied with, seal the clothes in an alginate bag (used also for washing biologically contaminated clothes, stitching dissolves in the wash), and wash in a washing machine Monitor again after washing d) Decontamination Kit Each department working with unsealed sources should keep an adequately stocked decontamination kit in their department. This kit should be stored in a readily accessible place, and an inventory should be kept of the items with a regular check carried out to ensure that the kit is complete. Recommended contents are as follows: Protective clothing, including, overalls, disposable gloves, appropriate particle/vapour mask/respirator, and disposable overshoes Miscellaneous equipment such as, plastic floor covering, plastic bucket, polythene bags with radiation trefoil, roll of paper towel, paper tissues, adhesive tape with trefoil symbol, large INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 23 tweezers, note book and pen, scissors, nail brush, warning signs with trefoil symbol, string, and marker pen Decontamination agents such as, soap, decon, potassium permanganate, sodium bisulphide, saline, sterile water, potassium iodide 4. Dealing with Personal Contamination a) External Personal Contamination Note: Do not use safety shower to remove contamination as this is likely to spread contamination further. Skin/Hands: Take care not to damage the skin. Do not scrub. Wash gently with water and a mild, non-abrasive soap, and use a soft nail brush if necessary. Dry with disposable towels. Monitor the area and repeat once or twice more. Try to reduce the spread of contamination by covering non contaminated areas of skin and cleaning the affected area towards the centre of the contaminated area. When dealing with skin contamination, pay particular attention to creases, folds, fingernails, inter-digital spaces and outer edges of the hand. If this is unsuccessful, and contamination persists, as a last resort hands may be steeped in 4% permanganate solution, allowed to dry and finally wiped with 5% sodium bisulphite solution. Wounds: Contaminated wounds should be washed under running water and reasonable bleeding should be encouraged. Care should be taken not to contaminate eyes, mouth or nostrils. The wound should finally be washed with water, dried by wiping away from the edges of the wound, and dressed. Monitor any swabs used for drying. Mouth: Remove any dentures and scrub if necessary. Warn the subject not to swallow. Wash the mouth out several times with water and brush teeth away from gums. Ensure that washings run away from other orifices. Eyes: Should be irrigated with water or saline solution, ensuring that the fluid dose not spread to other parts of the body, and in particular runs away from other orifices. Ear: Trained medical staff should be asked to syringe out contaminated ears with water at body temperature. Nose: Blow nose into a tissue and expectorate into a disposable cup. If the contamination is still high, then consider nasal irrigation, preferably under medical supervision. In undertaking nasal irrigation, it is important to tilt the head forward with the nasal bone roughly vertical so that irrigation fluid flows back out of the nostrils rather than into the nasopharynx or frontal sinuses. Irrigate with saline or sterile water. The subject should be seated with a waterproof cover over the trunk and lap, and can regulate the flow of liquid by pinching the irrigation tube which should be held just inside the nostril. Collect the irrigation fluid into a receptacle on the subject’s lap and monitor. Blow nose, expectorate, and monitor products and nasal orifices. Repeat irrigation if necessary. Hair: Shampoo hair with soap or cetrimide, making sure that the washings run off the head without contamination to other parts of the body, particularly orifices (eyes, ears, nose, mouth). If necessary, trim off affected area of hair and retain clippings for monitoring. INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 24 Nail: Cut away as much as possible of the contaminated nail and monitor the clippings. Decontaminate around and under the nail as for skin. Decontamination should continue until monitoring (swabs counted by LSC or Mini-Monitor, as appropriate) shows that contamination shows that contamination has been removed, unless there is a danger of contamination entering the blood from skin being broken by decontamination procedures. b) Internal Personal Contamination Where radioactivity has been ingested, medical attention should be sought immediately. Under medical supervision, various actions can be taken to eliminate certain radionuclides from the body or to reduce the absorption of radioactivity, as outlined below: Potassium Iodide will reduce thyroidal uptake of absorbed radionuclide Potassium perchlorate will reduce uptake of iodide and pertechnetate in breast milk and will displace pertechnetate from the thyroid, salivary glands and the stomach Increasing fluid intake will help to eliminate tritium Potassium ferric cyanoferrate (Prussian blue) will reduce uptake of thallium and caesium from the gut Chelates such as DTPA and EDTA with a high binding constant for metals will scavenge radiometals from the circulation and will then be excreted in urine It may be possible to administer a stable isotope of the radionuclide if not toxic Absorption of radioactivity from the gut can be reduced by: administration of competitive ions a stomach pump an emetic an enema absorption of radioactivity from the lungs can be reduced by pulmonary lavage, but the attendant risks and benefits must be considered It must be stressed that in all cases, the toxicity of any inactive compound must be known, and the administration must be carried out under medical supervision. Internal radioactivity must be monitored and the activity in tissue specimens assayed where possible in order to assess the effectiveness of any of these measures. Contact Details of Relevant Personnel: College RPO: Elaine Lee @ 6082887 College Safety Officer/Deputy College RPO: Tom Merriman @ 6081914 Contact details of RPII: Office hours: David Fenton, Jarlath Duffy, or John O’Grady @ 2697766 Outside office hours: The RPII operates a 24-hour, 7 day a week on – call system to provide a response to any accident or emergency situation involving radiation Contact details of Front Gate (for Access to all Emergency Services or assistance after normal working hours): 01 - 6081999 (external) or internal ext. 1999 Prepared by: Elaine Lee, Radiation Protection Officer INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 25 ELECTRICAL To help a person suffering from electric shock the following steps should be followed: Shout for help If possible switch off the power Release victim from contact when current is off If power cannot be switched off immediately, pull or push casualty clear using nonconducting material such as a wooden chair or brush handle Unless wearing thick rubber-soled shoes or boots, stand on lino rubber or wood while pushing victim clear Send for medical assistance If casualty is breathing, place in recovery position, then get casualty to Accident & Emergency Department If casualty is not breathing begin resuscitation procedure DO NOT TOUCH CASUALTY WITH BARE HANDS UNLESS POWER IS SWITCHED OFF INTRUDER During normal working hours: If you see or are approached by a stranger behaving suspiciously in the Institute, act discreetly You should feel free to request that person to identify themselves and their business in the Institute When in doubt, or if the person is acting in a hostile or violent fashion, contact Security at reception desk If no immediate response, contact St James Security, or as a last resort, the Gardai at Kilmainham Out of hours: When you sign in at Reception, check to see who else has signed in and out for that period. Anyone operating in the Institute who has not signed in must be regarded with suspicion Do not attempt to challenge strangers in the Institute out of hours Go to the nearest room where you can lock yourself in and use your mobile or nearby phone to ring St James Security. If no response phone Front Gate Trinity, or if no response there, phone Gardai at Kilmainham Remain in the locked room until security arrives INSTITUTE OF MOLECULAR MEDICINE Trinity Centre for Health Sciences, St James’s Hospital 2004 26