Semantics Enabled Industrial and Scientific Applications: Research, Technology and Deployed Applications Part II: A Healthcare Application Keynote - the First Online Metadata and Semantics Research Conference http://www.metadata-semantics.org November 23, 2005 Amit Sheth LSDIS Lab, Department of Computer Science, University of Georgia http://lsdis.cs.uga.edu Thanks to our collaborators the Athens Heart Center & Dr. Wingeth ©UGARF and Amit Sheth (except when attributed to someone else). Semantic Web and Life Science • Data captured per year = 1 exabyte (1018) (Eric Neumann, Science, 2005) • How much is that? – Compare it to the estimate of the total words ever spoken by humans = 12 exabyte • Death by data • The need for – Search – Integration – Analysis, decision support – Discovery 2 Not data, but analysis and insight, leading to decisions and discovery Ontologies are popular in life sciences and health care Semantic Web in Health-care and Life Sciences – Applications and Demonstrations 3 Active Semantic Document A document (typically in XML) with • Lexical and Semantic annotations (tied to ontologies) • Actionable information (rules over semantic annotations) Application: Active Semantic Patient Record for Cardiology Practice. - 3 populated ontologies - EMRs in XML 4 Practice Ontology 5 Practice Ontology 6 Drug Ontology Hierarchy (showing is-a relationships) 7 Drug Ontology showing neighborhood of PrescriptionDrug concept 8 First version of Procedure/Diagnosis/ICD9/CPT Ontology maps to diagnosis maps to procedure specificity 9 Active Semantic Doc with 3 Ontologies 10 Explore neighborhood for drug Tasmar Explore: Drug Tasmar 11 Explore neighborhood for drug Tasmar classification classification classification belongs to group brand / generic belongs to group interaction Semantic browsing and querying-- perform decision support (how many patients are using this class of drug, …) 12 More on ontologies, Languages and Rules • Schema • Population (knowledge source) • Freshness • Use of W3C standards (XML, RDF, OWL, RQL/SPARQL, SWRL) 13 On-line demo of Active Semantic Electronic Medical Record (deployed at Athens Heart Center) Comments on Evaluation 14 • Extreme User Friendliness – Electronic Health Record is the focus of all activities, no extra search, no switching of windows • Error Prevention • Decision Support • Better Patient Support and Insurance management 15 SW research @ LSDIS Semantic Middleware ASD • Ontology design and population • Automatic Metadata Extraction, Semantic Annotations • Semantic Computations: (Inference), Rules, Complex Relationships, Knowledge Discovery, Semantic Associations SemDis • Active Semantic Documents • Semantic Web Services/Processes • Semantic Discovery on Adaptive Grid Services WSDL-S • Semantic Applications: Bioinformatics, METEOR-S Health Care, Intelligence/Gov., SemGrid (Commercial: Risk & Compliance, Content Aggregators) • New themes: Semantics Enabled Networking Bioinformatics for Glycan Expressions & Middleware 16