RESPIRATORY SYSTEM DR. MOHAMED SEYAM, PHD. PT. ASS. PROFESSOR OF PHYSICAL THERAPY RESPIRATORY SYSTEM Respiratory tract: a) Upper respiratory tract b) Lower respiratory tract Pulmonary zones A. conducting zone B. Respiratory zone Broncho pulmonary segments Muscles of Ventilation, Surface Anatomy of lungs, Respiratory System 1. The Respiratory Tract A. The upper respiratory tract • Nose lined by ciliated columnar epithelium mucus secreting cells dense vascular network in submucosa filtering air warming air humidifying air sneezing reflex • Pharynx • Epiglottis Larynx vocal cords glottis B. The lower respiratory tract • • • • • Trachea Bronchi Bronchioles Respiratory bronchioles Alveolar ducts and alveoli NASAL CAVITY and PHARYNX *Nasal cavity Functions : Air conduction, Filtration ( by hair follicles), Humidification, Temperature control, Olfaction. *The pharynx: is a Musculomembranous tube approximately 5 to 6 inch long and located posterior to nasal cavity. It extends from the base of the skull to the esophagus. The Pharynx: consists of three parts 1. Nasopharynx - Extends from Nasal cavity to Soft palate 2. OroPharynx - Extends from Soft palate to upper border of epiglottis 3. Laryngopharynx - Extends from upper border of epiglottis to cricoid cartilage LARYNX Larynx is s complex structure made up of several cartilages and forms connection between the pharynx and trachea. The Position of trachea is opposite to third to sixth cervical vertebrae in the adult male and some what higher in females and children Six supporting cartilages, including * Three large - Epiglottis, thyroid, and Cricoid * Three smaller - Arytenoid, corniculate and cuniform It prevents food, liquid and foreign objects from entering the airway. Two sets of laryngeal muscles play important roles in swallowing, ventilation and vocalization . LOWER RESPIRATORY TRACT • Respiratory zones 1) Conducting zone(nose, pharynx, larynx, trachea, Bronchi, Bronchioles) to warm and humidify the air to distribute the gas to serve as part of body defense system 2) Respiratory zone(respiratory bronchioles, alveoli sac and duct) CONDUCTING AIRWAYS Tracheobronchial tree : Airway diameter is progressively decreases with each succeeding generation of branching, starting at approximately 1 inch in diameter at the trachea and reaching 1 mm or less at the terminal bronchioles Trachea: is a tube approximately 4 to 4.5 inches long and 1 inch diameter. Carina: It is cartilaginous wedge that marks bifurcation of trachea into the right and left main steam bronchi. This corresponds to Fifth (T5) thoracic vertebrae MAIN STEM BRONCHI Main stem or Lobar bronchi • Right main stem bronchus is wider, shorter, and more vertical than left stem bronchus and it diverges 25 degree angle from trachea (Note : Right main stem intubation more common than left) • Left main stem bronchus leaves trachea at an angle of approximately 40 to 60 degrees. Secondary Bronchi • One bronchi per each lobe of lungs • Three on the right lung • Two on the left lung Terminal units (Acinar Units) Tertiary Bronchi : supply Broncho pulmonary segments – Right lung has 10 segments – Left lung has 8 segments • they branch several times and eventually for bronchioles. Bronchioles: subsegmental, terminal, and respiratory • Respiratory passages less than 1 mm in diameter • Branch several times into terminal bronchioles which extend into gas exchange bronchioles • Branch into alveolar ducts Alveoli Alveolar ducts and sacs • The normal mature lungs contain about 300 million alveoli (150 million in each one), each of which is extremely small (between 200 to 300 micro meter in diameter) • Type I Squamous pneumocytes Covers approximately 93 % of alveolar surface. • Type II Granular pneumocytes produces surfactants • Alveolar Macrophages engulf and ingest foreign materials (Phagocytize) Terminal Bronchiole Respiratory Bronchiole alveolus Alveolar sac Alveolar ducts • Respiratory tract defense system Mucocilliary transport system: mucus escalator Cough reflex Macrophages Broncho Pulmonary Segments Bronchpulmonary segments of right lung Bronchpulmonary segment of left lumg Functions of Respiratory System Forms series of passages that conduct air to area where gas exchange will occur Provides surface area for gas exchange Protection of respiratory system from dehydration, temperature change, and pathogens Sites Of Respiration In The Body External respiration - Exchange of gases between atmosphere and blood tissue - Occurs in alveoli of lung tissue Internal respiration Exchange of gases between blood and cells of the body Cellular respiration Utilization of oxygen to create ATP through oxidative phosphorylation Krebs cycle SURFACE MARKINGS OF LUNGS Sternal angle is at the level of the fifth thoracic vertebra ( b/w 4 th 5 th ) * The second costal cartilage corresponding to the sternal angle is so readily found that it is used as a starting-point from which to count the ribs. * This is point at which trachea divides into two primary bronchus. Surface lines Mid sternal - the middle line ofthe sternum Para sternal - The Para sternal line runs parallel to the edge of the sternum Midclavicular - Which runs vertically downward from a point midway between the center of the jugular notch and the tip of the acromion. Axillary lines * Anterior axillary - vertically from the corresponding anterior axillary folds *Mid axillary - runs downward from the apex of the axilla. * Posterior axillary - vertically from the corresponding posterior axillary folds Bony markers related to lung Surfaces , Borders, And Apex Of Lungs Each lung has an apex, three surfaces (costal, medial, and diaphragmatic), and three borders (anterior, inferior, and posterior) The apices of the lung extend about 3 cm above the medial third of the clavicles then project inferolaterally to the junction of medial and middle thirds of clavicle. Anteriorly, the hila lie at the level of costal cartilages 3-4; this is vertebral level T 5-7. The inferior margins of the lung with corresponds to Vertebrae: T6 - Mid-clavicular line T8 - Mid-axillary line T10 - Posteriorly The Muscles Of Respiration The muscles of respiration consist of four groups: 1. the diaphragm 2. the chest wall muscles 3. the abdominal muscles 4. the muscles of the upper airway. The muscles of the upper airway include the muscles of the mouth (innervated by cranial nerves IX and X), uvula and palate (XI), tongue (IX and XII), and larynx (C1). While these muscles do not have a direct action on the thorax, they are essential for keeping the upper airway opened and because they affect airway resistance and airflow, may impact on lung volume . Properties of respiratory muscles The respiratory muscles, especially those that participate in normal quiet breathing, are skeletal muscles that differ from other skeletal muscles in three major ways; (1) They must contract rhythmically and intermittently throughout life, (2) The control of these muscles is both voluntary and involuntary, and (3) They must primarily work against elastic (chest wall and lungs) and airway resistive loads, rather than against the gravitational forces encountered by most other skeletal muscles. Main muscles of respiration INSPIRATORY MUSCLES Muscle Innervations Inspiratory , primary Diaphragm C3-C5 Intercostals T1-T11 Scalene Anterior C3-C4 Middle C5-C6 Posterior C6-C8 Inspiratory, accessory Sternocleidomastid C2-C4 and accessory N. (XI) Trapezius C1-C4 and accessory N. (XI) EXPIRATORY MUSCLE Expiratory muscles nerve supply Rectus abdominus T6-T12 Transversus abdominus T2-L1 Internal and external obliques T6-L1 Pectoralis major Medial and lateral pectoral N. (C5- T1) The triangularis sterni or transvarsus thoracis References 1- Essentials of Cardiopulmonary Physical Therapy, 3rd edition, Ellen Hillegass DPT CCS FAACVPR, Saunders elsevier; 2011. 2- Cardiovascular and Pulmonary Physical Therapy: Evidence to Practice Elizabeth Dean PhD PT, Saunders Elsevier;2012 3- Cardiac rehabilitation, Louis R. Amundsen, Churchill Livingstone; 1981. THANK YOU