CHAPTER 3 NEUROSCIENCE AND BEHAVIOR (BIOLOGY AND BEHAVIOR) Biological psychology: the study of the relationship between biology and behavior and mental processes The nervous system is the primary path of communication in your body neurons: special cells that receive and transmit information from one part of body to another In the brain we have approximately 3 types of neurons 1. sensory (afferent) neurons: transmit messages from sense organs to the brain or spinal cord (including messages from internal organs and skin) 2. motor (efferent) neurons: transmit information from brain or spinal cord to muscles and glands; help us move our arms, legs, etc. 3. interneurons: transmit messages between neurons Most neurons are interneurons (in the nervous system) 3 Parts of a Neuron 1. cell body-- sometimes called the soma; contains the nucleus ; gives the neuron energy to function and can receive information; also contains genetic material 2. dendrites-- short fibers that extend out from the cell body receive signals from other neurons some dendrites have more branches than others; this allows the neuron to receive more information 3. axon-- thin, tube-like structure that extends out from the cell body Sends information from neuron to other neurons, a gland, or a muscle Not all neurons have axons, and the ones that do have axons have only one Axons can vary in size, can be long or short The axon ends in the axon terminal, it transmits signals to the dendrites, other cell bodies, muscles, glands Neurons are not connected together Between the axon terminal and the receiving neuron is a tiny gap called the synaptic cleft synapse-- the point of communication between the axon terminal of a neuron and a receiving neuron Sending neuron—presynaptic neuron Receiving neuron—postsynaptic neuron How the Neuron Communicates On the outside-- sodium ions which are positively charged On the inside-- potassium ions which are negatively charged When the neuron is at rest, it has more negative ions inside, More positive ions outside, When at rest, the neuron is at millivolts of electricity This is called the resting potential When the neuron is stimulated, the electrical impulse does not travel down the neuron When the neuron is disturbed just a little, it’s no longer resting and it reaches threshold (a minimal disturbance) It gets to be fully stimulated and the sodium channels open and sodium rushes into the cell, then the channels close, this makes the cell more positive inside Very soon after the sodium channels close, the potassium channels open and potassium rushes out of the cell, then those channels close, making the cell more negative outside The neuron becomes more positively charged at events is called the action potential millivolts and this series of The action potential is based on the “all-or-none” law, meaning that the neuron fires completely or not at all How does it get back to its resting potential? Sodium ions begin to flow out of the neuron and potassium ions begin to flow back in So the neuron is back at -70 millivolts a neuron can fire up to action potentials a second the impulse will travel faster if the axon is covered with myelin sheath, a white, fatty coating that acts as insulation for the axon by protecting it from other axons The impulse on an axon with the myelin sheath can travel myelin sheath faster than without the nodes of Ranvier: gaps between the segments of the myelin sheath where the electrical impulse is regenerated at each node If there is damage done to myelin along the axon, messages that are transmitted can be slowed or interrupted The result is You will see this in multiple sclerosis, which has degeneration of parts of the myelin sheath glial cells: are even smaller than neurons and they outnumber neurons by 10:1 Other functions of glial cells 1) 2) 3) 4) Neurotransmitters Messages between neurons are transmitted by chemical messengers called neurotransmitters: little chemical messengers Neurotransmitters are held in the synaptic vesicles , little sacs in the axon terminal When an action potential reaches the axon terminal, the synaptic vesicles release their neurotransmitters inside it and the neurotransmitters move into the synaptic cleft Neurotransmitters have a distinctive shape; the receptor site of the receiving cell is coordinated with the shape of the neurotransmitter Acetylcholine: first neurotransmitter to be discovered; is found in all motor neurons This is the neurotransmitter that helps you to move, stimulates muscle contractions, stimulates muscle movements as small as blinking your eyes or as big as jumping a hurdle Is also important for Loss of memory in is associated with a loss of acetylcholine Dopamine: Involved in movement People with have a depletion of dopamine in their brains; move rigidly, have tremors; movements aren’t synchronized or don’t flow smoothly; sometimes it’s just hard for them to get moving; also affects speech Also involved in the reward center of our brains Ex: Serotonin:Is involved in your emotional states and sleep Lower levels of serotonin can lead to depression Need serotonin to sleep The higher the level of serotonin, the sleepier you will be THE CENTRAL NERVOUS SYSTEM The central nervous system can be seen as the central processing center of your body; everything that you do, sense, feel, or think has to be processed through your central nervous system Our nervous system has two parts: The spinal cord is about the size of your little finger in diameter and has tons of glial cells The spinal cord does not have to act with the brain, it can act alone For instance, the spinal cord can act without the brain to protect us from being injured Ex: THE BRAIN About how much does your brain weigh? Brainstem That part of the brain right at the top of the spinal cord and at the base of the brain Many of our are controlled by parts of the brainstem medulla: controls breathing, heart rate, digestion, blood pressure, coughing, and swallowing Any damage is usually fatal Ex: reticular formation: regulates sleep and attention If it’s very active, we are alert If it’s slow, we go to sleep pons: it connects the right and left cerebellum Helps coordinate body movements for each side of the body cerebellum: controls basic muscle coordination and movements; movements are more fluid-like, more smooth Also controls Ex: Damage to the cerebellum: Ex: The Limbic System thalamus: processes sensory and motor information and sends the information to higher brain areas Most information that comes in (except for the thalamus before it goes to other parts of the brain ) has to stop by Also involved in hypothalamus: a small, peanut-sized structure located under the thalamus Regulates those behaviors that we need to survive, like eating, drinking, sexual and emotional behavior Also regulates amygdala: important for expressing emotions Involved in emotions like fear and anger If it’s stimulated, person can show fear in a situation hippocampus: important in forming new memories If damaged or destroyed, you will not be able to store or recall any new information You can remember old information because old memories are not stored in the hippocampus It affects only those memories after the damage Ex: THE CEREBRAL HEMISPHERES The cerebral cortex is the outer covering of the brain and is made up of two halves called the cerebral hemispheres The cerebral cortex is only about 1/8” thick and is very wrinkled and gray; where the term “gray matter” comes from Controls memory, thinking, and language Hemispheres are connected by the corpus callosum, a thick band of axons that allows the right and left hemispheres to communicate with each other Each hemisphere controls the opposite side of the body Right hemisphere controls feeling and movement for the left side of the body Left hemisphere controls feeling and movement for the right side of the body Lobes of the Brain 1) frontal lobe: the largest lobe, the front part of the brain Involved in planning, thinking, executing voluntary movements, creativity, and emotions 2) parietal lobe: involved in processing sensory information, including touch, temperature, and pressure; in the middle Helps us identify things by touch, such as a pencil 3) occipital lobe: receives and interprets visual information; located at the back of the brain 4) temporal lobe: receives and interprets auditory information; located by your temples BRAIN DAMAGE Damage to certain parts of the brain can result in severe impairment or death stroke: most common cause of injury to the adult brain and is the 3 rd most common cause of death Occurs when blood supply is cut off to part of the brain, brain doesn’t get enough oxygen and brain cells are killed Can be caused by a blood clot, hemorrhaging in the brain, etc. Can lead to head injury result in impaired motor coordination Can lead to Recovering from brain damage Once you lose neurons, they are gone forever and cannot be replaced If have damaged neurons, they can sprout new dendrites and make new connections with other neurons If lose some abilities because of damage, other areas can take over the functioning if they are near the site; you can regain those abilities Plasticity-- where the brain reorganizes and compensates for damage done show greater levels of plasticity because all the connections have not been made yet THE PERIPHERAL NERVOUS SYSTEM Contains all the nerves that are on the outside of the central nervous system; connects the central nervous system to the rest of your body Divided into 2 subdivisions: 1) Somatic Nervous System Transmits information from sensory receptors to central nervous system AndTransmits messages from central nervous system to motor nerves to muscles Controls voluntary movements 2) Autonomic Nervous System Controls involuntary functions Transmits information between central nervous system and the heart, smooth muscles, and glands Involuntary functions include The autonomic nervous system is broken down into two subsystems: 1) sympathetic nervous system: turned on when you need to use energy Usually turned on in emergencies; also includes heightened emotions Symptoms: Is called the fight-or-flight response, how your body prepares you to fight or run from something that’s dangerous 2) parasympathetic nervous system: tries to conserve energy and is turned on after an emergency to calm you down THE ENDOCRINE SYSTEM Made up of glands throughout the body and they communicate with other parts of the body by manufacturing and secreting hormones Hormone: chemical messengers that are released into the bloodstream to other parts of the body It affects whatever part of the body it is released to pituitary gland-- called the master gland; about the size of a pea and located right under the brain Controlled by the hypothalamus Controls the hormones produced by other glands in the endocrine system Produces the hormone that thyroid: controls your body’s metabolism, produces a hormone called thyroxin adrenal glands: produces norepinephrine and epinephrine (also called adrenaline) These hormones turn on your sympathetic nervous system They are hormones and pancreas: regulates your blood sugar levels by releasing insulin into your bloodstream gonads: sex glands in females called the In males called the Needed for reproduction Responsible for secondary sex characteristics during puberty (girls develop breasts, boys voices get deeper, etc.) The male sex hormones are androgen and testosterone, which influences sex drive The female sex hormones are estrogen and progesterone and they help to regulate the menstrual cycle Both males and females are born with these hormones, just in different proportions