Background Paper 22. September, 2000 The selfish interpretation of the Convention on Biological Biodiversity by the University of Lausanne, Switzerland NGOs in Zimbabwe and Switzerland condemn the way by which the University of Lausanne gained access to genetic resources in Zimbabwe and the way the benefit sharing has been negotiated. They also reject the patent on antimicrobial diterpenes which Prof. Hostettmann of Lausanne University took out on these resources and which is based on traditional knowledge. This case is another example of how current bioprospecting in southern countries contradicts the rules defined by the Convention on Biological Diversity (CBD). “While the Swiss government supports guidelines for Access and Benefit Sharing at the CBD, a Swiss University is engaged in illegal bioprospecting activities in Zimbabwe”, says François Meienberg of the Swiss NGO Berne Declaration. On July 27, 1999, US-patent 5’929’124 on antimicrobial diterpenes was granted to Kurt Hostettmann, professor at the University of Lausanne. The patented invention relies on traditional knowledge from Zimbabwe and on the root of the tree "Swartzia madagascariensis" that can be found throughout tropical Africa. Two years before, in April 1997, an addendum to a material transfer and confidentiality agreement between the American pharmaceutical company Phytera and the University of Lausanne was signed, under which Phytera received an option for an exclusive worldwide license and in return agreed to pay royalties of 1.5% on the net sales of any product marketed under this license. Professor Hostettmann, on the other hand, is obliged to give 50% of any royalties received to the National Herbarium and the Botanical Garden of Zimbawe and to the Department of Pharmacy at the University of Zimbabwe. The aforementioned NGOs criticize the following aspects of this deal: Neither the state of Zimbabwe, nor the traditional healers affected by the bioprospecting have been correctly informed or have given their prior informed consent for the search of genetic resources in Zimbabwe. The Convention on Biological Diversity, signed by Zimbabwe and Switzerland, states that "access to genetic resources shall be subject to prior informed consent (pic) of the contracting party providing such resources …". In Zimbabwe the mandate and the authority to allow access to genetic resources lies with the Ministry of Environment. But the Ministry never signed a contract with the Universitiy of Lausanne, nor is there any contract which shifts the mandate from the Ministry to the University of Zimbabwe, which helped the University of Lausanne to get access to the resources . The African Model legislation for the regulation of access to biological resources states that the pic of the state and the concerned local communities is needed. Part of the information requested for the pic should be the economic, social, technical, biotechnological, scientific, environmental, or any other benefits that are intended or may be likely to accrue and the proposed mechanisms and arrangements for benefit sharing. The concerned stakeholders (traditional healers, local communities, the state of Zimbabwe) were not given any of this information before the University of Lausanne gained access to genetic resources and traditional knowledge. “We have never given our consent to this deal”, states Prof. G. Chavunduka of the Zimbabwe National Traditional Healers Association (ZINATHA) which had submitted a number of samples of their medicines to the University of Zimbabwe for analysis. “The idea was just to confirm the properties of this medicine which traditional healers have been using for time immemorial.” There have been no mutually agreed terms for a fair and equitable benefit sharing mechanism. An agreement signed between the University of Zimbabwe and the University of Lausanne stipulates that in the event of finding any product which may require the application of intellectual property rights, this will be subject of joint negotiation and application. Contrary to Article (F) of this agreement, as the Chairperson of the Pharmacy Department indicated, the University of Zimbabwe did not take part in the negotiation process between the University of Lausanne and Phytera. No one has consulted stakeholders in Zimbabwe on whether they agree with the amount of royalties they are to receive. Indeed, the amount negotiated between the University of Lausanne and Phytera is very low compared to other benefit sharing agreements. The average range of royalties on net sales for materials with value added data such as ethnobotanical information is 1–4% (tenKate/Laird 1999), including exceptional cases of up to 50% (in a contract between the Swiss Federal Institute of Technology and Venezuela). In the case of "Swartzia madagascariensis", moreover, a low benefit sharing percentage must be shared with an intermediary, the University of Lausanne. A patent taken out on illegally accessed genetic resources should be declared invalid. However, as patent offices do not consider the origin of patented materials, the current patent regime in fact supports biopiracy. NGOs also request further analysis of whether Professor Hofstettmann’s ‘invention’ actually fulfills the requirements for a patent (e.g. novelty), or if it is largely based on illegally acquired traditional knowledge. “In this case, the involved NGOs are willing to fight the patent at the US patent and trademark office” states Andrew Mushita of the Community Technology and Development Association (CTDA) in Zimbabwe. A documentary telecast by Swiss television in June indicates that other bioprospecting projects of Prof. Hostettmann (e.g. the search for a natural “Viagra” medicine on behalf of the Swiss pharma giant Novartis) have also been carried out in violation of the CBD. Phytera already made headlines in 1996, when - in an attempt to circumvent the Biodiversity Convention - they proposed plant sampling contracts to botanical gardens in the North without any provision for benefit-sharing with the countries of origin. Several botanical gardens in Germany rejected such contracts. Swiss and Zimbabwean NGOs demand that in the case at hand an access and benefit sharing agreement be negotiated that fulfills the objectives of the Biodiversity Convention and involves all the main stakeholders in Zimbabwe. The NGOs also demand that the contract between the University of Lausanne and Phytera be cancelled and the patent withdrawn. For further information: Andrew Mushita: CTDA, Tel: 00263 4 30 31 60; email: tactdtms@harare.iafrica.com François Meienberg: Erklärung von Bern, Tel : 0041 1 277 70 04 ; email : food@evb.ch Prof. G. Chavunduku: ZINATHA, Tel: 00263 4 77 28 80 or 00263 4 75 19 02