BAM Online Meeting March 28, 2007 Team Members Present: Richard Bornhorst Kathryn Poole Deepak Janardhanan Robert Grillo Shubh Krishna Meeting length: 90 minutes Discussion of model issues o Need to address the s(t)+e(t) statements in the denominators of the equations because the non-linearity causes computational concern This may be resolved with the new definitions of input parameters as percentages Using percentages raises the problem of finding real input data, since most prior research uses rates (#/time) Percentages may not remove the s(t)+e(t) denominator from the Q1Q2 and Q1R transitions May require splitting Q1 into two states Can easily remove s(t)+e(t) from SR, EQ1, and SQ1 Removing the non-linearity will make it difficult to redefine alpha and phi Using all percentages may make it difficult to evaluate constraints Example of possible solution: if the constraint is 10,000 vaccines per day, then it can be set to 0.01, so phi*s(t) will never break (since s < %100) Discussion of final report draft o Initial work will be composed of bulleted information, converted to paragraph form by the group, and revised by the editor-in-chief, Rick o As time gets closer to the final report due date, the team will post project changes directly to the final report draft, rather than in separate sections Discussion of analysis plan o Group will consider using the effective reproductive number, Ro, as a result parameter for overall comparison of cases Ro definition: the average number of secondary cases produced by a typical infectious individual during its infectious period Preparations for class on 3/29 o Present copies of equations, final report draft, and other documents to demonstrate our progress to Dr. Laskey and receive comments Action items and assignment of responsibilities: o Rick – Final report draft o Kathryn – Equation updates o Shubh – Equation updates o Deepak – Matlab analysis o Rob – Reproductive number summary