How Has The National Policy To Prevent The Metabolic Syndrome Been Developed In The Japanese Ministry Of Health? -To Facilitate The Healthier Longevity SocietyAt ECOSAC Regional Ministerial Meeting on Financing Strategies for Health Care 16-18 March 2009 Colombo, Sri Lanka Kiyotaka SEGAMI, M.D., Ph.D. Executive Board-Director Welfare and Medical Service Agency The former Minister’s counsel in health segami-k@umin.ac.jp segami200819@wam.go.jp Financial Concerns -Containment of -- Social Concerns -Better QOL Medical Concerns –Better Health Business Concerns -Finding Chances Aging Population Issues Sustainability in Policy Feeling Not Unhappy, Not in Poverty among Citizen 28 Sept 06/ Segami, K Depiction of Medical Expenditure Growth Increase of medical Expenditure A n al ys i s o f fac to rs Increase of Medical Expenditure of the elderly is a Major Factor Aging of the population Per Capita Medical Expenditure of the Elderly 1.5 ratio of elderly to non-elderly Large Variation of Per Capita Medical Expenditure for the elderly (Average \750,000, Highest:\900,000, Lowest:\600,000) Increase of Inpatient Medical Expenditure per Patient Increase of Outpatient Medical Expenditure per Patient Large number of Beds (Long Average LOS) Prevalence of Lifestyle-related Disease in Outpatient Low Home Care Rate Increase of Patients with Life Style-Related Disease due to Visceral Obesity / Adipose Tissue Japanese Trial in Various Methods of Controlling Medical Expenditure <Chronic> + Promotion of Home Care Improvement of Residence Other than Home Referral System at Discharge <Acute> Functional Specialization and Referral System According to Acute Phase, Rehab Phase, Nursing Care Phase and Home Care Phase of illness Decrease of Average Length of Stay Reduce Admission Rate by Preventing the occurrence of Severe Diseases Outpatient Medical Expenditure Prevention of Lifestyle-Related Diseases (Medical Check-ups and Health Advice by Insurers etc.) Reduce the incidence of diseases Home Visit for Patients with patients with duplicate care and Frequent Outpatient Visit Containment of Medical Expenditure Growth Inpatient Medical Expenditure Conversion of Long-term in-patients to Nursing Care Promotion of Terminal Care at Home Control of Medical Expenditures involving All Stakeholders Patient (Insured) ・ Effort to Improve Lifestyle ・ Appropriate Physician Visit Effective Health Care ・ Achieving Early Discharge, Reduction of he Number of Beds Providers ・ Creating Incentives for Patients to Pass Away at Home or Nursing Facilities by Improving Home Care Reduce Prevalence Rate of Life-style Related Disease ・ Implementing Health Checkup and Insurers Health Education to Prevent Life-style Related Disease Shorten average Length of Stay (LOS) Containment of Health Care Expenditures ・ Review of the universal fee schedule National Government to produce effective health care ・ Budgetary steps for Prefectures to guide healthcare providers ・ Planning & implementing plan for Medical Prefectures Expenditures Control, and Health Promotion Planning, Health Care Planning, Long-term Care Insurance Planning ・ Guidance of Municipalities Municipalities ・ Promotion & Education of prevention of life-style related disease ・ Enhancing the provision of nursing care as a foundation of home care Steps for Promoting Effective Health Care Development of Stages of Life-style Related Diseases and Medical Care Expenditure in 2004 Physical Inactivity Visceral Obesity Metabolic Syndrome 50% / Male 40yrs+ 20% / Female Unhealthy Diet Smoking accelerates all stages of development and more damages Sleep Apnea Hypertension Diabetes 5,939,000 patients receive medical care Medical Exp: 8 Billion USD 2,284,000 p Med Exp:12 B USD (7,400,000 Suspected + 8,800,000 Possible) Arteriosclerosis Cerebrovascular D. Ischemic H. D. 1,374,000 p Annual Death: 130,000 Annual Occur: 234,000 Med Exp: 17 B USD 911,000 p Annual Death: 72,000 Med Exp: 6.8 B USD 47.2 B USD Amputation from Diabetic Neuropathy Ann. Registry: 3,000 Diabetic Nephropathy Vision Loss from Diabetic Retinopathy Ann. R.: 3,000 Hemodialysis from Renal Failure (For Reference) Malignant Neoplasm 230,000 p Annual Incr: 14,000 Med Exp: 3.4 B USD 1,280,000 p Annual Death: 305,000 Med Exp: 21.4 B USD Medical Concerns on Hypertension Genetic Factor Insulin Resistance RAS Activity SNS Activity Salt Sensitivity Drugs (30-50% influence) Salt Intake Physical Inactivity Mental Stress Visceral Obesity Hypertension Cardiovascular/Renal Complications Status of the paralyzed after stroke Status of the sight-lost after retinal hemorrhage Life Style Modification Kamide K, et al. Jp Heat J 2004 Financial Concerns Numbers of Patients and Latent ones Cost of Medical Care Medical Expenditure in Future PREVENTION Public Health Approach Number and Status of Renal Failure and the Dialyzed Social Concerns Status Quo: Hypertension in Japan • Receivers of medical services – 5,939,000 are under the medical care due to Hypertension. (2004) – 9.2% of total “receivers” • Medical Expenditure for Hypertension – 946 BJY (=8,085 MUSD) in 2004 • 19.9% for Inpatient, 80.1% for Outpatient – 7.8% of Total Medical Expenditure (12,106 BJY) • Latent Patients estimated – Patients are estimated 31,000,000 – persons at risk are also estimated 20,000,000 • Hypertension is not only the medical issue, but also the national financial one Health adjusted Life Expectancy and Years Lost of Life Expectancy due to Hypertension Male 0 yrs 65 yrs 75 yrs 85 yrs Life Expectancy in 1995 77.7 17.6 10.7 5.8 Health Adjusted LE Hypertension 68.3 16.2 9.4 4.7 9.4 1.3 1.3 1.1 Years Lost of Life Expectancy Female Life Expectancy in 1995 Health Adjusted LE Hypertension Years Lost of Life Expectancy 0 yrs 65 yrs 75 yrs 85 yrs 84.6 22.5 14.2 7.7 77.1 18.7 12.1 7.6 7.5 3.8 2.1 0.1 Segami, K(2006) Life Table Analysis of Hypertension in Female Japanese Years of Life Lost from Hypertension is 569,237 personyears at 65yrs of female. In other words, the differences of life expectancies are 3.8 years from 22.5 years at age 65. (From Life Table and Vital Statistics in 2000) Power of Mortality at the age of Diagnosis of Hypertension Age 30's 50's 60's 70's 80's Power 5.0 Times 2.2 Times 2.1 Times 2.4 Times 1.0 Times From the JAPAN DATA by Okayama et al. By Segami, K 2006 Output: Suppressing increment of ME for the Elderly Health Promotion Suppressing Onset of Dis. Suppressing Aggravation of Dis. Medical expenditure per Capita Threshold of onset Risk Factors for Onset (Preventable) Total measures of controlling Visceral Obesity and Diabetes and other Risk Factors will cause suppressing the Medical Expenditure for the Elderly Aging (Preventive measures are effective for suppressing the Medical Expenditure of Diabetes, which will cause the complication after 25 yrs to 70% of patients.) Depiction of Medical Expenditure Growth Necessity of Systematic Measures Countermeasures to Suppress Life Style Related Diseases ①Spread of Integrated and Consistent Health Promotion by Insurers and Regional Officials (Significant is to increase their motivation.) ②Complete and Efficient Medical Check ups (Based on evidence from mega cohort study.) ③Individual Health Advice for High-Risk Groups (By well-trained Health Personnel.) 1,325M USD to be allocated in 2007 Functional Specialization and Referral System of Medical Facility Acute Stage Rehabilitation Chronic Stage Home Care referral Nursing Care System Respect for Local Daily Activity of the elderly Systemic Approach to change Mechanism of delivery of Health Services Schematic Image of Medical Coordination (in case of stroke) [Acute Illness] [Subacute/ Recovery Phase] Community Emergency Care Services Rehab Function (Recovery Phase) Use of Longterm Care insurance (if necessary) (Transfer Coordination) (Discharge Coordination) (Discharge Coordination) (Referral Coordination) (Referral (Care house, Coordination) Nursing home etc.) (Discharge Coordination) Primary Care Function (Clinic, Hospital etc.) Discharge Onset of Disease Living at Nursing Facility Care Function (Including Rehab) Discharge Home Care (Continuity care) Management, Education Living at Home Discharge Discharge The theoretical understanding of the visceral obesity as the starting point of most of those diseases Countermeasures toward the more effective prevention of these diseases Insulin Resistance Diabetes Care 19, 287, 1996 Diabetes, Hyperlipidemia Left Ventricular Dysfunction Metabolism 36, 54, 1987 Am J Cardiol 64, 369, 1989 Bio-active Mediators from Adipose Tissue Visceral Obesity Hypertension Hypertension 16, 484, 1990 Hypertension 27, 125, 1996 Coronary Diseases Atherosclerosis 107, 239, 1994 Int J Obesity 21, 580, 1997 Sleep Apnea J Int Med 241, 11, 1997 All by Prof. Matsuzawa Y. et al With complimentary regards Prevention of Onset and Progression of Lifestyle-Related Diseases High Blood Pressure High Blood sugar High Blood Lipid ○High blood glucose, High blood pressure, Hyperlipidemia do not progress separately. These are like ”The tips of a single iceberg”. Visceral fat ○Medication (ex. Hypoglycemic agent) merely reduces the size of ”one tip of the iceberg”. ○It is necessary to reduce the size of “whole iceberg” by improving life style, such as adherence to physical exercise and improved diet. Improvement of Life Style Adherence to physical exercise Increase of energy consumption, Cardiovascular activity Improved Diet ・Adherence to Exercise ・Improved Diet ・Quitting Smoking Reducing caloric intake, Balanced Nutrition Activation of Metabolism / Reduction of visceral fat (Good Hormone↑ , Bad Hormone↓ ) Continuation One medication merely reduces the size of one tip of iceberg. It does not cure the whole disease. 1.Exercise 2. Diet Appropriate blood sugar, pressure, lipid Reduction in weight and waist circumference Feeling of Well Being Smaller Iceberg! 3.Non-Smoking Drug is last resort Comprehensive Implementation of Medical Expenditure Control 1. Ensuring a Balance between rising health care costs and the public financial burden Rising Health Care Costs Moderation in Health Care Cost in the mid-andlong term (Decrease the number of metabolic syndrome patients, at-risk group, decrease the Average Length of Stay etc.) Review of the coverage policies of public health insurance etc. (Short-term Policies) Evaluate from both perspective Ensuring consistency with the New Health Promotion Plan, new Health Care Planning Incremental Effects Evaluate from an economic perspective Ensuring Secure and Reliable Health System Moderating Public Burden Present a clear estimate of medical spending in the future including mid-& long-term prospects for about 5 years = Use as a way to examine the rising health care costs after a certain period of time Examine the effectiveness of the control policies by comparing the estimated and actual costs Future review of policies Comprehensive Implementation of Medical Expenditure Control 2. Promoting Plans for Medical Expenditures Control The national government and prefectures must work together in; • Promulgating systematic measures to control medical expenditures, including of long-term hospitalization those regarding lifestyle-related disease prevention and those for rectifying the problem. (2) Taking steps to support plan implementation. Formulating such plans in a manner consistent with health promotion plans and long-term care insurance will ensure coordination between policy actions. (3) Conducting examinations to verify that the plan is being implemented. * Excerpt from Outline of Health Care Reform Policy For Longevity and Healthier Life • Death is inevitable, but a life of protracted ill-health is not. • A half but most, in future, of cardiovascular diseases do/will not result in sudden death. • Rather, they are likely to cause people to become progressively ill and debilitated, especially if their illness is not managed correctly. • Prevention and control of Cardiovascular disease helps people to keep longer and healthier lives. The speaker appreciates your kind attention. See you soon. Something else • Lest of all, just for your sight…. Status Quo: Cardiovascular diseases in Japan Background of policy-making toward the prevention of the metabolic syndrome Population, Birth, and Death in Japan 140,000,000 2800000 120,000,000 2400000 100,000,000 2000000 80,000,000 1600000 60,000,000 1200000 40,000,000 800000 20,000,000 400000 19 50 19 52 19 54 19 56 19 58 19 60 19 62 19 64 19 66 19 68 19 70 19 72 19 74 19 76 19 78 19 80 19 82 19 84 19 86 19 88 19 90 19 92 19 94 19 96 19 98 20 00 20 02 20 04 0 0 In 2006 Population12 7,720 T Over 65 yrs 26,400 T (20.7%) Death est. 1,600 T Increment of Cardiovascular Deaths CVD + Stroke: 303,000 and 28% of total deaths in 2005 CVD 2005 171,000 15.9% 2004 132,000 12.3% 159,625 15.5% 2000 129,055 12.5% 146,741 15.3% Stroke Malignant Neoplasm 324,000 30.1% 132,529 13.8% 165,478 121,944 1980 161,764 123,505 320,358 419,564 40.8% 295,484 386,899 30.7% 40.2% 217,413 162,317 Others 450,000 41.8% 31.1% 1990 0 CVD + Stroke:Inpatient310T、Outpatient850T Mal Neoplasm:Inpatient140T、Outpatient110T 315,470 275,215 500,000 1,000,000 3000 0 0 yr s+ 1000 89 6000 90 2000 ~ 9000 84 3000 85 12000 ~ 79 4000 80 Physician Visit ~ 5000 75 ye 1 ar ~ 5 4 ~ 10 9 ~ 1 15 4 ~ 1 20 9 ~ 2 25 4 ~ 2 30 9 ~ 3 35 4 ~ 3 40 9 ~ 4 45 4 ~ 4 50 9 ~ 5 55 4 ~ 5 60 9 ~ 6 65 4 ~ 6 70 9 ~ 7 75 4 ~ 79 0 Anual Prevalence (estimated) / 100 000 100,000) visits (per first physician rate of theRate Incident Annual Annual Incident Rate of Cardiovascular Diseases Prevalence Rate of Cardiovascular Diseases 15000 Admission 1 year after Cerebrovascular Events Death 48,511(20.7%) Annual Occurrence 234,352 (100%) Alive 185,841(79.3%) To be decreased in future Institutionalized 13,195(5.6%) Bed-bound at Home 17,469(7.4%) Home help needed 30,850(13.2%) Independent(Partially) 67,460(28.8%) Recovery 57,053(24.3%) To be increased Outline of Health Care Reform Policy (Government and Ruling Parties Council on Health Care Reform (December 1st, 2005) <Contents> Ⅰ Guiding Principles for the Reform 1. Ensuring safe and reliable healthcare while emphasizing prevention 2. Comprehensive Implementation of Cost Containment 3. Creating a new health insurance system accounting for the aging of society Ⅱ Ensuring safe and reliable healthcare while emphasizing prevention 1. Ensuring safe and reliable healthcare 2. Emphasizing prevention Ⅲ Comprehensive Implementation of Cost Containment Ⅳ Creating a new health insurance system accounting for the aging of society Ⅴ Reviewing the universal fee-schedule etc. Ⅵ Reform timing Ⅱ. Ensuring safe and reliable healthcare while emphasizing prevention Basic structure Ⅱ - 1. Policy Outline “Ensuring Safe and Reliable Healthcare” → (1) Establishing a new structure capable of providing safe, secure and high-quality health care upon the consumers’ perspective Ⅱ - 2. of the Policy Outline “Prevention as a centerpiece” → (2) Establishing a new structure focused on prevention of lifestyle-related diseases (1) Establishing a new structure capable of providing safe, secure and high-quality health care upon the consumers’ perspective - Enabling people to obtain sufficient healthcare information Assistance in healthcare decision-making by providing healthcare information - Information collection and release by prefectures --> Instituting a structure under which a medical institution can register its available healthcare service offerings with the prefecture, which then disseminates such information in an easy-to-understand way. - Clearly presenting to residents and patients at the regional level, in the form of a health care planning, the healthcare services which are available, as well as the details of inter-institution coordination. - Widening the range of information advertised. - Enabling people to receive safe and high-quality healthcare Provision of unfragmented healthcare by promoting specialization and coordinating provision of healthcare services - Establishing a system of regional healthcare coordination for respective fields of healthcare, such as stroke, cancer and pediatric emergency care, by reconsidering the health care planning. - Providing, within a system of regionally coordinated healthcare, unfragmented healthcare through the wider application of networked critical pathways. * Regional coordinated critical pathways A treatment plan up until a patient goes home after being treated in an acute-care hospital and then a rehabilitation hospital. Information-sharing between the patient and his or her medical institution leads to the provision of efficient and high-quality healthcare as well as the patient's peace of mind Ensuring appropriate healthcare provision even takes into account a patient’s care after discharge or transfer. - Enabling people to recover quickly and return home Improved quality of life (QOL) for patients through well-developed home healthcare services Forecast of Medical Expenditure (Estimate based on reform plan, January 2006) FY2006 FY2010 FY2015 FY2025 27.5 (trillion) 31.2 (trillion) 37 48 % of National Income 7.3% 7.4% ~ 7.7% 8.0% ~ 8.5% 8.8% ~ 9.7% % of GDP 5.4% 5.4% ~ 5.6% 5.8% ~ 6.1% 6.4% ~ 7.0% 28.5 (trillion) 33.2 (trillion) % of National Income 7.6% 7.9% ~ 8.2% 8.7% ~ 9.2% 10.3% ~ 11.4% % of GDP 5.5% 5.8% ~ 5.9% 6.3% ~ 6.6% 7.5% ~ 8.2% (Budget) Projection after reform Without Reform (status quo) 40 (trillion) 56 (trillion) (trillion) (trillion) National Income 375.6 (trillion) 403 ~ 420 (trillion) 432 ~ 461 (trillion) 492 ~ 540 (trillion) GDP 513.9 (trillion) 558 ~ 576 (trillion) 601 ~ 634 (trillion) 684 ~ 742 (trillion) (Assumption of the estimate) 1. “Without Reform” refers to the projected expenditures under the current health insurance law with an unrevised universal fee schedule. The increase of Medical Expenditure per capita is extrapolated from past data (2.1% for people below 70 and 3.2% for people above 70) 2. “After Reform” refers to the Budget in 2006 and when the revision of health insurance law etc. and the revision of the universal fee schedule are implemented 3. Nominal Economic Growth used in the calculation of National Income and GDP is based on two cases, “Basic Case” and “Risk Case”. Both cases are using the same assumption of “Reform and Prospect 2005 (Draft)” (until 2011) and “Recalculation for Pension Finance 2004” (from 2012) Changes in Nominal Economic Growth 2006 2007 Basic Case 2.0% 2.5% Risk Case 2.0% 1.9% 2008 2.9% 2.1% 2009 3.1% 2.2% 2010 3.1% 2.1% 2011 3.2% 2.2% 2012~ 1.6% 1.3% Status Quo: Diabetes in Japan Background of policy-making toward the prevention of the metabolic syndrome Prevalence of Diabetes in Japan 40 Female Diabetes Suspected Diabetes Diagnosed Diabetes Suspected Diabetes Diagnosed 20〜29 30〜39 Male 35 Prevalence Rate 30 25 20 15 10 5 0 40〜49 Age 50〜59 60〜69 70〜 2002 Diabetes Survey by Ministry of Health Correlation between Physician Visits for Diabetes and Mortality from Renal Failure (Correlation Coefficient: 0.721) P revalence of D iabetes V S M ortality from C hronic R enalFailure correlation coefficiet:0.721 M ortal ity C R F (per 100,000 capita) Failure Mortality Rate from Renal R 2 = 0.5192 22 18 14 10 100 120 140 160 180 200 220 P revalence D ibabetes 240 260 280 Incident Rate of the first Physician Visits from Diabetes (per 100,000 capita) 300 Correlation between Physician Visits for Diabetes and Mortality from Pneumonia (Correlation Coefficient: 0.638) P revalence of D iabetes V S M ortality from P neum onia correlation coefficiet:0.638 M ortal ity P neum oni a 100,000 capita) (per Pneumonia Mortality Rate from 110 R 2 = 0.4069 80 50 100 120 140 160 180 200 220 P revalence D ibabetes 240 260 Incident Rate of the first Physician Visits from Diabetes (per 100,000 capita) 280 300 Status Quo: Hypertension in Japan Background of policy-making toward the prevention of the metabolic syndrome Status Quo: Hypertension in Japan • Receivers of medical services – 5,939,000 are under the medical care due to Hypertension. (2004) – 9.2% of total “Patients”. • Medical Expenditure, burden of cardiovascular diseases – 946,000,000,000JY (=8,085 MUSD) in 2004 for Hypertension » 187,9 BJP for Inpatient » 758,1 BJP for Outpatient – 7.8% of Total Medical Expenditure (12,105,600 MJY) Correlation between Physician Visits for Hypertension and Mortality fromP reval Renal Failure (Correlation Coefficient: 0.753) ence of H ypertension V S M ortality from C hronic R enalFailure ortalityFailure C RF (per 100,000 capita) Mortality Rate of from MRenal correlation coefficiet:0.753 13 R 2 = 0.5678 9 5 300 350 400 450 500 550 600 P revalence H ypertension 650 700 Incident Rate of the first Physician Visits by Hypertension (per 100,000 capita) 750 800 Correlation between Physician Visits for Hypertension and Mortality from Cerebral Infarct (Correlation Coefficient: 0.653) M ortal ity C erebral Infarct(per 100,000 capita) Infarct Cerebral Mortality Rate from P revalence of H ypertension V S M ortality from C erebralInfarct correlation coefficiet:0.653 R 2 = 0.4266 90 60 30 300 350 400 450 500 550 600 P revalence H ypertension 650 700 Incident Rate of the first Physician Visits by Hypertension (per 100,000 capita) 750 800 Decrease of Mortality in 5 years (1997-2002) from Cerebral Hemorrhage Correlation between Physician Visits for Hypertension And Decreases of Mortality in 5 years (1997-2002) from Cerebral Hemorrhage other Cerebral C orrel ation betw een Incidence of Hand ospital V isit byminor H ypertensi on A nd D. D ifferences of M ortality after 5 years (1997-2002) from Coefficient: C erebrovascular-0.327 D iseases)Except B rain H em orrhage,Infarction (Correlation (C orrelation C oefficient:-0.327 ) 0.5 0 300 350 400 450 500 550 600 650 700 750 -0.5 -1 -1.5 -2 R 2 = 0.1071 -2.5 -3 -3.5 -4 Incidence of the first Physician Visits for Hypertension 800 Correlation among these diseases Background of policy-making toward the prevention of the metabolic syndrome The prevention from the starting point as the most appropriate countermeasure Countermeasures toward the more effective prevention of these diseases • To prevent Visceral Obesity, Risk Factor Control by individual behavior changes; – Spread of Integrated and Consistent Health Promotion by Insurers and Regional Officials (Significant is to increase their motivation.) – Complete and Efficient Medical Check ups (Based on evidence from mega cohort study.) – Individual Health Advice for High-Risk Groups (By well-trained Health Personnel.) • 1,325M USD to be allocated in 2007 What can we do as the population approach? From the desk plan to the social movement The dawn of the national policy on Metabolic syndrome Group – Stepping in to the academic round-table conference on making the Japanese version of diagnostic standard of metabolic syndrome – The achievement of agreement among the high officials in the Ministry of Health on what-to-do – Involvement of the stakeholders – Discussions on the Ministerial Council – The appropriation to the budget compilation of the National Government and exploitation – To the deliberations on Congress The dawn of the national policy on Metabolic syndrome Group • The characteristics of the Japanese version of metabolic syndrome: Abdominal perimeter Male: 85cm, Female: 90cm (From the employee based cohort study with MRI, only accomplished in Japan)