Avogadro Scale Engineering Molecular Machine (Jacobson) Group MIT – June 2004 Molecular Machines (Jacobson) Group red blood cell ~5 m (SEM) DNA proteins nm Simple molecules <1nm diatom 30 m bacteria 1 m 10-10 10-9 10-8 10-7 10-6 m 10-5 10-4 10-3 10-2 SOI transistor width 0.12m Semiconductor Nanocrystal ~1 nm Nanotube Transistor (Dekker) 1012 bits/cm2 (1Tbit/cm2) Circuit design Copper wiring width 0.1m IBM PowerPC 750TM Microprocessor 7.56mm×8.799mm 6.35×106 transistors Fabricational Complexity •Total Complexity •Complexity Per Unit Volume •Complexity Per Unit Time*Energy •Complexity Per unit Cost Ffab = ln (W) / [ a3 tfab Efab ] Ffab = ln (M)e-1 / [ a3 tfab Efab ] Fabricational Complexity Genome (Natural) Design Rule Smallest Dimension (microns) 0.0003 Number of Types of Elements 4 Area of SOA Artifact (Sq. Microns) NA Volume of SOA Artifact (Cubic Microns) 6.E+01 Number of Elements in SOA Artifact 3.E+09 Volume Per Element(Cubic Microns) 2.E-08 Fabrication Time(seconds) 4.E+03 Time Per Element (Seconds) 1.E-06 Fabrication Cost for SOA Artifact($) 1.E-07 Cost Per Element 3.E-17 Complexity 4.E+09 Complexity Per Unit Volume of SOA(um^3) 7.E+07 Complexity Per Unit Time 1.E+06 Complexity Per Unit Cost 4.E+16 Cost Per Area NA Gene Chip (Chemical SemiParallel conductor Synthesis) Chip 0.0003 4 7.E+08 5.E+06 7.E+04 8.E+01 2.E+04 3.E+02 1.E+02 2.E-03 9.E+04 2.E-02 6.E+00 9.E+02 2.E-07 0.1 8 7.E+10 7.E+09 7.E+12 1.E-03 9.E+04 1.E-08 1.E+02 2.E-11 2.E+13 2.E+03 2.E+08 1.E+11 2.E-09 High Speed Offset Web 10 6 2.E+12 2.E+12 2.E+10 1.E+02 1.E-01 7.E-12 1.E-01 6.E-12 4.E+10 2.E-02 3.E+11 3.E+11 6.E-14 TFT 2 8 1.E+12 1.E+11 3.E+11 4.E-01 7.E+02 2.E-09 2.E+03 6.E-09 6.E+11 5.E+00 9.E+08 3.E+08 2.E-09 Liquid DVD-5 Embossing 0.5 2 1.E+10 7.E+12 5.E+10 2.E+02 3 7.E-11 3.E-02 7.E-13 3.E+10 5.E-03 1.E+10 1.E+12 3.E-12 0.2 4 8.E+09 8.E+08 2.E+11 4.E-03 6.E+01 3.E-10 2.E-01 1.E-12 3.E+11 3.E+02 5.E+09 1.E+12 3.E-11 …Can we use this map as a guide towards future directions in fabrication? Moleography – MIT 15 nm Direct Beam Fabricated Structures Ridley, B.A., B. Nivi, and J.M. Jacobson,. Science, 1999. 286(5440): p. 746-749 (First Demonstration of All Inorganic Active Devices (Transistors) Solely from Nanoparticle Building Blocks). Bulthaup, C.A.,Jacobson et al.. Applied Physics Letters, 2001. 79(10): p. 1525-1527. Ridley, B.A., et al.,. Materials Research Society Symposium Proceedings, 2000. 581\ Griffith, S., et al.. Journal of Vacuum Science & Technology B, 2002. 20(6): p. 2768-2772. Jacobson Group –2004