Anatomy & Physiology 34B Study Guide for Lecture Exam #! To prepare for the first lecture exam, be sure to review the information in the lecture outlines on the special senses, autonomic nervous system, and endocrine system, as well as related textbook material. The first lecture exam will consist of 100 multiple choice questions over this information. You will need a #882 Scantron and a number 2 pencil. Study hard and good luck! Special Senses - Compare and contrast general senses with special senses. Where are each found in the body? - What five factors are necessary to perceive a sensation? - What are the five types of sense receptors classified by the way they are stimulated? - What are the two types of distributions of sense receptors in the body? - What are the three types of sense receptors classified by their origins of stimuli? - Compare and contrast phasic vs. tonic receptors. Give examples of each. - What are the two major types of general sense receptors? Give examples of each. - What are the accessory structures of the eye? What are their two main functions? - What two main structures lubricate the eye surface? What type of lubricant does each produce? - Name and locate the 6 extrinsic eye muscles. What eye action(s) is each responsible for? What cranial nerve controls each muscle? - What are the 3 basic layers of the eye? What is the main function of each layer? - Know the structures of the fibrous tunic (sclera, cornea, limbus), and their functions. - Know the structures of the vascular tunic (choroid, ciliary body, ciliary muscle, suspensory ligaments, lens, iris, pupil) and their functions. - What is presbyopia? Cataracts? What part of the eye is affected by these conditions? - What are the two main layers of the sensory tunic (retina)? What major structures/cells are found in the neural layer? - Where are the two main cavities of the eye found? What type of fluid is contained in each? - What is glaucoma? What eye structures are involved? How is it detected? What happens if it is not treated? - How is light entry into the pupil controlled? What two iris contractile elements are involved? Which dilates the pupil and which constricts it? - What 4 substances in the eye refract incoming light, and in what order is the light refracted? - Describe how the eye is affected by astigmatism, emmetropia, myopia, and hyperopia. - What three main process occur in the eye during the near response? How is the lens affected? - What are the two types of photoreceptor cells? Which type is responsible for black & white vision? For color vision? What types of pigments are found in each? Which part of the pigment is responsible for nerve transmission in the rods & cones? - What three major types of neural cells are found in the retina? In what order do the receive light and transmit nerve impulses? - What happens in the eye when you go from dark to light? From light to dark? 2 - Compare where the rods are found in the retina vs. where the cones are found. Why do cones produce a sharp color image, whereas rods produce less clear image? - What are the three types of cones and how do they allow us to see many different colors? - What is colorblindness? What is deficient in the cones of colorblind people? - What is stereoscopic vision? How does it allow us to see in 3 dimensions? - Trace the visual projection pathway from the photoreceptors to the brain. What region of the brain interprets sight? - What are the three main regions of the ear? Which structures are involved in hearing? In equilibrium? - What structures are found in the outer ear? Which structure vibrates with incoming sound waves? - What structures are found in the middle ear? What transmits the sound vibrations to the inner ear? What is the function of the eustachian tube? - What is otitis media? How can it be alleviated? - What two tiny skeletal muscles are found in the middle ear? What is their main function? - Why is the inner ear called the labyrinth? What are the two main parts of the labyrinth? - What fluid is found in the bony labyrinth? In the membranous labyrinth? - What are the three main divisions of the bony labyrinth? Which are involved in equilibrium, and which is involved in hearing? - What sensory structures are found in the utricle and saccule of the vestibule? How do the structures function in the detection of linear acceleration? - What sensory structures are found in the ampullae of the semicircular ducts? How do the structures function in the detection of head rotation? - Describe the equilibrium projection pathways to the brain. What region of the brain controls skeletal muscle coordination and balance? - What are the three chambers in the cochlea? What type of fluid is found in each? - Describe the sensory structures in the cochlea involved in hearing. - How are incoming sound waves transmitted through the ear structures? - How does the ear distinguish between loudness and pitch of incoming sounds? What cochlear structures are involved in each? - Describe the auditory projection pathway to the brain. What region of the brain interprets sounds? - What is the difference between conduction deafness and nerve deafness? - Describe the structures involved in olfaction, and the sequence in which odor nerve impulses are transmitted to the brain. What region of the brain interprets odors? - Describe the structures involved in the gustatory (taste) sense. - What are the three main types of tongue papillae? Where are each found on the tongue? Which contain functional taste buds? - What are the 5 basic tastes? - Which two cranial nerves transmit taste impulses to the brain? What region of the brain interprets tastes? Autonomic Nervous System - How do the somatic and autonomic nervous systems differ? 3 - Compare and contrast preganglionic and postganglionic motor neurons in the sympathetic and parasympathetic nervous systems. Where are their cell bodies found? What types of neurotransmitters do they release? - What part of the spinal cord is involved in the sympathetic NS? - What is significant about the fact that sympathetic preganglionic neurons synapse with many postganglionic neurons, whereas parasympathetic preganglionic neurons only synapse with one or two postganglionic neurons? - By what 3 main routes do sympathetic postganglionic neurons exit the paravertebral ganglia? What other major ganglia is involved? What major organs are innervated by each route? - How are the adrenal medullas involved in the sympathetic NS? - What parts of the brain and SC are involved in the parasympathetic NS? - Where are the ganglia for the parasympathetic postganglionic neurons located? - Describe the 4 cranial nerves involved in the parasympathetic NS. Which carries most of the preganglionic fibers, and what organs does it innervate? - Which division of the PNS is considered cholinergic? Adrenergic? Why? - Describe the two types of cholinergic receptors, where they are found, and what types of postsynaptic potentials they produce - Describe the 4 types of adrenergic receptors, whether they are excitatory or inhibitory, and what type of second messengers they stimulate - How can sympathetic and parasympathetic nerves serve the same organs, yet often produce different responses in the organs? - Know the examples of sympathetic and parasympathetic responses given in class. - What organs are controlled only by the sympathetic NS, and not the parasympathetic NS? - What other areas of the CNS help to regulate the Autonomic NS? Endocrine System - What is a hormone? What is meant by a target tissue for a hormone? Why don’t all tissues respond to all hormones passing by them in the blood? - Which glands are completely endocrine glands? Which organs are partially endocrine? - What is the general method whereby hormones (and neurohormones) work? In what major ways do the mechanisms of amines, peptide and steroidal hormones differ? (e.g., extracellular signal transduction vs. intracellular protein synthesis) - What are the three basic chemical classes of hormones? From what organic molecules are the three classes derived? Which hormones are included in each class? - Compare and contrast the formation of peptide, amine, and steroidal hormones in cells. What cellular organelles are involved in the synthesis of each type of hormone? - How does the transport of peptide hormones differ from that of steroidal hormones? - How does the hypothalamus control the secretions of both the anterior and posterior pituitary glands? List the neurohormones produced by the hypothalamus. - What are catecholamines, and where are they produced? - How do the anterior and posterior pituitary glands differ from each other? - Describe the basic functions of the two neurohormones produced in the hypothalamus and stored in the posterior pituitary gland until needed. 4 - Describe the basic functions of the 7 hormones produced by the anterior pituitary gland. How do the trophic and nontrophic hormones differ? - What regulates the amount of a particular hormone that is present in the bloodstream at a given time? (Hint: How does negative feedback work?) - What is meant by synergism, permissiveness, and antagonism in terms of hormonal interactions? Give examples of each. - In addition to hormonal hypersecretion or hyposecretion, what other problems can cause abnormal target tissue responsiveness? (Hint: think about hormone receptors.) - Describe up- and down-regulation of receptors in the cell membrane. What causes these actions to occur? - In terms of endocrine pathologies, how do primary and secondary pathologies differ? - In what three ways can glands be stimulated to release their hormones? Give examples of each method. - What glands are stimulated to release their hormones via the trophic hormones from the anterior pituitary gland? - Which hormones are mainly anabolic in their actions, and which are primarily catabolic? - What causes the pancreas to secrete insulin or glucagon? What are the target organs and effects of these hormones? Compare and contrast type 1 and type 2 diabetes mellitus. - What are the three regions of the adrenal cortex, and what hormones does each region produce? - Where is cortisol produced, and what are its actions? With what other hormones does cortisol have permissive effects? What pathologies result from cortisol hypo- and hypersecretion? - What two hormones do the two different cell types in the thyroid gland secrete? What are the functions of the two hormones? What hormone is produced by the parathyroid glands? - How is thyroid hormone synthesized? What element (ion) is needed to synthesize thyroid hormone? In what functional way does the amine thyroid hormone differ from other amine and peptide hormones? - What are the symptoms of hyper- and hypothyroidism, and what conditions result from each? - How is the release of growth hormone regulated? What are the target organs of GH? What hormone is released by the liver in response to GH, and what are its effects? - What conditions result from the hypo- and hypersecretion of GH? - In addition to GH, what other things are needed for normal tissue growth to occur? What other hormones have permissive effects with GH? - What three hormones regulate blood plasma calcium levels, and how do they do so? Where is the majority of calcium found in the body? - Why is it necessary to maintain calcium homeostasis in the bloodstream? (For what functions is calcium needed in the body?) What occurs in hypo- and hypercalcemia?