AbstractID: 6557 Title: Comparison of Techniques for Microwave Heating of Primary Tumors of the Breast There is growing interest in microwave heating as an adjuvant treatment for breast tumors, as shown in phase III trials [C. C. Vernon et al, Int. J. Rad. Oncol. Biol. Phys. 35:731 (1996)]. This study was made to determine how to select the appropriate techniques for heating a tumor with a specific shape, size, and location. The methods used in this study included measurements in phantom models, and numerical modeling. The heating techniques that were evaluated include the use of two 915 MHz waveguide applicators compressing the breast, a 915 MHz cylindrical phased array of dipole antennas with a water bolus surrounding the breast, and a lower frequency (100-200 MHz) circularly-polarized spiral applicator. There is a common misconception that a breast tumor would always heat more than the surrounding fat tissue because of its higher water content. The results show that the polarization has a significant effect when heating non-spherical tumors. The relative SAR in the tumor is greatest when the electric field is parallel to the long-axis of the tumor. When the electric field is normal to the long axis, the tumor SAR is decreased and the SAR of adjacent mammary tissue is increased. Circular polarization with the spiral applicator overcomes some of the polarizationdependent effects, and the lower frequency causes improved penetration. Two-dimensional phase-steering with a cylindrical phased array provides greater control of the heating than onedimensional steering with two opposing waveguide applicators. This work was supported by the BSD Medical Corporation.