NASA Human Research Program Investigators' Workshop 2012
sess241.pdf
Tuesday, February 14, 2012
BONE
:00 p.m. Tanglewood
Chairs:
Jean Sibonga
Tom Lang
3:00 p.m.
Hargens A. R. Chiang S. B. Sayson J. V. Parazynski S. E. Chang D. G.
Garfin S. R. Lotz J. C.
Mechanism of Post-Flight Herniation of Intervertebral Discs [#4002]
Herniated intervertebral discs are frequent in space crew members after return to Earth. Pre- and
post-flight imaging, functional testing, pain questionnaires of ISS crews will ascertain mechanisms of
degeneration and injury to spinal structures.
3:15 p.m.
Bloomfield S. A. Macias B. R. Lima F. Shirazi-Fard Y. Swift J. M. Hogan H. A.
Wiggs M. P. Fluckey J. D. Greene E. S. Allen M. R. Cunningham D. A. Yuen E.
Camp K. Braby L. A.
Simulating Lunar Surface Missions: Partial Weightbearing and Low Dose/High Energy Radiation
Impact on Bone Loss [#4234]
Mice exposed to partial weightbearing (1/6G) and modeled galactic cosmic radiation (300 MeV 28Si)
or reference x-ray radiation in acute or fractionated doses exhibit loss of bone. Effects of radiation on
bone mass vary by weightbearing status and type of radiation.
3:30 p.m.
Spatz J. M. Fields E. E. Yu E. W. Divieti Pajevic P. Bouxsein M. L. Sibonga J. D.
Zwart S. R. Smith S. M.
Retrospective Study of Serum Sclerostin Measurements in Bed Rest Subjects [#4048]
Key words: bone loss, sclerostin, disuse, bed rest, immobilization, bone density.
3:45 p.m.
Hanson A. M. Rice A. J. Wilt G. L. Gilkey K. G. Grodsinsky C. M. Cavanagh P. R.
Monitoring Mechanical Stimulus to Bone in Simulated Lunar and Martian Activities [#4233]
Subjects performed activities in simulated martian and lunar gravities to test an activity monitoring
system (AMS) which has application in exercise prescription and activity recognition.
4:00 p.m.
Qin Y-X. Cheng J. Bi L. Pritz M. Ferreri S. Rubin C. Lin W.
Quantitative Ultrasound Bone Diagnosis and Guided Therapy for Fracture Healing [#4225]
To evaluate the efficacy of a scanning confocal acoustic navigation (SCAN) system for bone quality
and fracture assessment in interested region; and to test guided ultrasound in acceleration of fracture
healing in a hindlimb suspension model.
4:15 p.m.
DISCUSSION