November 29, 2012 You are a tube inside a tube… Digestive Tract Gastrointestinal tract (GI tract) Four Stages of Food Processing Alimentary Canal 1. Ingestion - the taking in or eating of food. ¶ ¶ ¶ Muscular tube that passes through the body - mouth to the anus The tube is open at both ends 6.5 - 9 m in length Digestive Tract: Oral cavity (mouth) Pharynx Esophagus Stomach Small Intestine Large Intestine Anus Accessory Organs: Salivary glands Pancreas Liver Gall bladder 2. Digestion - the breakdown of food by mechanical & chemical processes into molecules small enough for cells of the body to absorb. There are 2 types of Digestion: 1) Mechanical/Physical Digestion · · · · the physical breakdown of food into smaller pieces. it involves - chewing, chopping, and grinding of food smaller food pieces = increases its surface area . done by teeth, beak or other similar structures, and by rugae and contractions/churning motions in the stomach. November 29, 2012 2) Chemical Digestion · the chemical breakdown of nutrient/macromolecules into smaller molecules by enzyme action (hydrolysis). Carbohydrases Carbhydrates (polysaccharides & dissacharides) Proteins Fats/Lipids (triglycerides) Proteases Lipases monosaccharides (simple sugars) 3. Absorption - the transport of the products of digestion from the digestive system into the circulatory system. the simple molecules(eg. glucose & amino acids) are transported in the blood to body cells where they are joined to make larger molecules or broken down to provide energy amino acids glycerol + 3 fatty acids 4. Elimination - the removal of undigested solid waste matter from the body through the anus. Nucleases Nucleic Acids nucleotides Enzyme Activity Enzymes - protein molecules that increase the speed of chemical reactions · 2 main factors can affect enzyme action/function: 1. Temperature - as temperature increases, enzyme activity increase. - if temperature becomes too hot, an enzyme will unfold from its 3-D shape ( Denaturation ), thus resulting in a loss of function. 2. pH - changes in pH can also cause enzymes to denature - different enzymes function best at different pH levels - optimal pH. Oral Cavity (The Mouth) The primary functions of the oral cavity (mouth) is to ... · to break up food particles - mechanical digestion · to lubricate food particles - saliva · begin digestion of complex carbohydrates (starches & glycogen) - chemical digestion The mouth is also used for tasting food (using the tongue) to help determine if it should be ingested or not. November 29, 2012 Mechanical digestion in the oral cavity ( mouth) involves: · Teeth - to break up food into physically smaller food particles (Mastication ) · Tongue - position/move food around mouth · Salivary Glands - secrete saliva to lubricate food & introduce salivary amylase (enzyme) Your teeth look different from one another because they are designed to do different things. Incisors - the sharpest teeth, built to cut food and shaped to shovel the food inward. Canines - meant for grasping and tearing food and thus, they have very long roots. Premolars - meant for crushing food and thus, have a more flat chewing surface. Molars - much bigger than the Premolars and have bigger, flatter chewing surfaces because their job is to chew and grind the food into smaller pieces. Chemical digestion in the oral cavity (mouth) involves: · Salivary Amylase - an enzyme that chemically breaks down the polysaccharides (carbohydrates). BOLUS - the mass (ball) of food that has be chewed at the point of swallowing. November 29, 2012 Esophagus The esophagus is a muscular tube that transports food from the mouth to the stomach. Its inner surface is lined with mucus. 4 layers of the Esophagus & the GI tract Food is prevented from travelling down the trachea (windpipe) by the epiglottis. The movement of food down the esophagus (and intestines) involves the process of Peristalsis. Peristalsis - a distinctive pattern of involuntary smooth muscle contractions that propels the bolus distally through the esophagus and intestines. Between swallows, the esophagus usually does not contract. There is a sphincter muscle separating the esophagus from the stomach (called the lower esophageal sphincter ) which normally stays tightly closed to prevent acid in the stomach from washing up into the esophagus. However, when we swallow, this sphincter muscle opens up (relaxes) so that the food we swallow can enter the stomach. The most common problem associated with the esophagus is Heartburn (Acid Reflux), which occurs when stomach acid backs up into the esophagus repeatedly and irritates the lining of the esophagus. This happens when the lower esophageal sphincter does not work/contract close properly. GERD - Gastroesophageal Reflux Dieses antacids (temporarily neutralize stomach acids) OR medications can reduce that amount of acid production in the stomach · both will help relieve some of the symptoms of gastroesophageal reflux.