Molecular View of Anatomy
Ya-Min Chi
1S0V
Tyr 639 helps RNA polymerase
to determine ribose structure
and deoxyribose structure. Its
stabilized by magnesium ion.
The Tyr 639 helps RNA
polymerase to read the DNA
template strand for
transcription. The hydroxyl
group on the Tyr interact with
the OH group of substrate
ribose. This is how Tyr help
determine ribose and
deoxyriboe.
Complete Biological Assembly for
1HHO
1HHO
Hemoglobin (2HHB) 1.74Å
vs
Myoglobin (1MBO) 1.6Å
Sulfate
ion
This image is the superposition of myoglobin (purple) with chain A of hemoglobin
(white). In general, the backbone structure of the two structures are really similar.
However, at the end of the structure, myoglobin is longer. This might prevent
myoglobin from forming a stable tetramer with itself.
The yellow surfaces show the hydrophobic region of the two
structures. From this, we see that hemoglobin has more hydrophobic
region on the surface than myoglobin has. Thus, hemoglobin form a
tetramer to reduce the surface of hydrophobic interaction.