Xuewen Wang, PhD
Office: 803-777-7272
Email: xwang@mailbox.sc.edu
Address:
921 Assembly St., Room 301
Columbia, SC 29208
RESEARCH INTERESTS
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Interactions among physical activity, sleep, energy balance, and insulin sensitivity in populations at
risk for cardiometabolic diseases
Energy expenditure in relation to body weight and body composition
Women’s health and aging
EDUCATION
Postdoctoral
2008-2010, Metabolism
Center for Human Nutrition
Washington University School of Medicine, St. Louis, MO
2005-2008, Exercise Physiology/Gerontology
Section on Gerontology and Geriatric Medicine
Wake Forest University School of Medicine, Winston-Salem, NC
Graduate
PhD (2006), Educational Research/Exercise Physiology,
Outside Supporting Field: Epidemiology
University of Miami, Coral Gables, FL
MSEd (2002), Exercise Physiology
University of Miami, Coral Gables, FL
Undergraduate
Bachelor of Medicine (1996)
Peking University Health Science Center, China
Workshop
First Short Course on Strengthening Causal Inference in Behavioral Obesity
Research, by UAB Office of Energetics and NHLBI (R25HL124208) (2015)
NIH Regional Seminar, Program Funding and Grants Administration (2015)
2nd Annual Isotope Tracers in Metabolic Research, Little Rock, AR (2009)
American Heart Association 35th Ten-Day Seminar on Epidemiology and
Prevention of Cardiovascular Disease, Tahoe City, CA (2009)
RESEARCH AND TEACHING EXPERIENCE
Jan 2012 -
Assistant Professor, Department of Exercise Science, School of Public Health, University of
South Carolina, Columbia, SC
2010 – 2011
Research Assistant Professor, Division of Geriatrics and Nutritional Science, Washington
University School of Medicine, St. Louis, MO
Wang, Xuewen
January 2016
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2008 – 2010
Research Associate, Center for Human Nutrition, Washington University School of
Medicine, St. Louis, MO
2005 – 2008
Research Fellow, Section on Gerontology and Geriatric Medicine, Wake Forest University
School of Medicine, Winston-Salem, NC
Summer 2003 Physical Activity Epidemiology Intern, National Center for Chronic Disease Prevention
and Health Promotion, Centers for Disease Control and Prevention (CDC), Atlanta, GA
1999 – 2005
Graduate Assistant, Laboratory of Clinical and Applied Physiology, University of Miami,
Coral Gables, FL
CLINICAL EXPERIENCE
2002 – 2003
Cardiovascular Rehabilitation Intern, Miami Cardiac & Vascular Institute, Baptist Hospital,
Miami, FL
1996 – 1999
Clinician, Internal Medicine, Beijing Jiu Xian Qiao Hospital, China
HONORS AND AWARDS
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2002, 2004
2003 - 2004
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1999 - 2005
Travel Stipend, American Heart Association 35th Ten-Day Seminar on Epidemiology and
Prevention of Cardiovascular Disease
Second Place, American College of Sports Medicine Nutrition Group Research Award
Outstanding Doctoral Student, School of Education, University of Miami
Travel Award, Graduate Activity Fee Allocation Committee, University of Miami
Who’s Who Among Students in American Universities & Colleges in recognition of
outstanding merit and accomplishment as a student at the University of Miami
Graduate Award for Scholarship, School of Education, University of Miami
Honorable Mention, Graduate Student Research & Creativity Forum, University of Miami
Science & Research Millennium Award, Clinical Immunology Laboratory, University of
Miami School of Medicine. June 5, 2000
Provost Graduate Student Travel Award, University of Miami
Graduate Assistantship, School of Education, University of Miami
MENTEE HONORS AND AWARDS
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Charity Breneman, one of the top eight finalists for Best Poster Award, Southeast American College
of Sports Medicine annual meeting 2016.
Charity Breneman, Second place in Student/Fellow/Resident Research and Projects category, 21st
Annual Diabetes Fall Symposium for Primary Health Care Professionals 2015
Ryan Porter, Third Place for Future Leaders Poster Award, Asia Pacific Conference on Exercise &
Sports Science 2015
Joshua Sparks, Arnold School Graduate Fellowship, 2015-2016
Ryan Porter, SMART (Student Mentor Academic Research Training) Award 2015 sponsored by
eBioscience, $2500 in reagents based on listed price.
Charity Breneman, inductee for 2015 Delta Omega Honorary Society in Public Health, Mu Chapter
(honorary society for graduate students in public health). Concurrently enrolled in MSPH in
Epidemiology, will complete in Fall 2015.
Ryan Porter, Arnold School Graduate Fellowship, 2014-2015
Julian Greer, first place, Exercise Science & Physical Education, University of South Carolina
Discovery Day, 2014
Julian Greer, recipient of Magellan Scholar, Magellan Mini-Grant and Magellan Apprentice Awards,
2014
Wang, Xuewen
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Charity Breneman, Doctoral student research award finalist, Southeast American College of
Sports Medicine annual meeting, 2013
Charity Breneman, Third place in Student/Fellow/Resident research category, Diabetes Fall
Symposium for Primary Health Care Professionals 2013
PROFESSIONAL MEMBERSHIPS AND CONSULTING RELATIONSHIPS
Grant Reviewer
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American Heart Association, Behavioral Science – Clinical committee, 01/2016 – 06/2016
USC Magellan Scholar Grant Review Committee 2015 Spring, 3 proposals and committee
meetings
USC Magellan Scholar Review Committee 2014 Fall, 8 proposals and committee meetings
National Institutes of Health, Special Emphasis Panel/Scientific Review Group 2014/10 ZNS1
SRB-G (78) (G78/NSD-K) meeting, scheduled for 06/19/2014-06/20/2014
USC Magellan Scholar application reviewer 2014 Spring, 2 proposals
National Institutes of Health, Skeletal Muscle Biology and Exercise Physiology Study Section
(SMEP), Special Emphasis Panel/Scientific Review Group 2013/01 ZRG1 MOSS-Q (14) B
“Small Business: Skeletal Muscle” meeting, scheduled for 11/14/2012-11/15/2012
Oak Ridge Associated Universities (ORAU) ad hoc reviewer, 2012
Manuscript Reviewer
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Reviewer for:
Age
BMC Public Health
BMJ Open
British Journal of Cancer
Clinical Intervention in Aging
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Endocrinology & Metabolic Syndrome: Current Research
Endocrinology
Gerontechnology
International Journal of Obesity
Journal of Gerontology: Medical Science
Journal of Health, Population and Nutrition
Journal of International Society of Sports Nutrition
Journal of Physical Activity and Health
Journal of Sport and Health Science
Medicine & Science in Sports &Exercise
Medical Science Monitor: International Journal of Experimental and Clinical Research
Nutrition Journal
Obesity
Psychoneuroendocrinology
Western J Nurs Res
National Meeting Abstract Reviewer
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American Public Health Association annual meeting program reviewer, 2015 – present
American Heart Association joint conference on Epidemiology and Prevention and Lifestyle and
Cardiometabolic Health, 2010 – present
Wang, Xuewen
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Gerontological Society of America annual meeting, 2014 - present
Professional Affiliation
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Member of American Diabetes Association (ADA), 2014-present
Member of American Heart Association (AHA), 2007-present
Member of American College of Sports Medicine (ACSM), 2003-2009, 2012-present
Member of American Physiological Society (APS), 2015
Member of Gerontological Society of America, 2013-2014
Member of The Obesity Society (formerly North American Association for the Study of Obesity,
NAASO), 2002-2010
Member of Washington University Association of Women Faculty, 2010-2011
Member of American Statistical Association (ASA), 2004-2007
PROFESSIONAL SERVICES
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ASPH Strategic Planning – Faculty Development committee member, 2015-2016
National Exercise Clinical Trials Network (NextNet) USC EXSC contact, 2015USC Walker Institute faculty associate, 2015 –
EXSC undergraduate division member, 2015EXSC Center for Exercise Research Center (CERC) advisory committee member, 2014USC Faculty Senate member, Fall 2014-Aug 15, 2017, 3-year term
USC BBIP (Behavioral-Biomedical Interface Program) affiliated faculty, 2014EXSC Department Executive Committee member, Aug 2014EXSC Applied Physiology division member, 2012 EXSC Health Aspects of Physical Activity division member, 2012 Served as Judge for 58th University of South Carolina Science and Engineering Fair, March 2014
Participated in Exercise Science Department Chair interviews, Jan 2014
ASPH Information Technology and Resources committee member, 2012-2015
Participated in faculty candidate interviews 2012, 2014, 2015
PUBLICATIONS
List of Published Work in My Bibliography:
http://www.ncbi.nlm.nih.gov/myncbi/xuewen.wang.1/bibliography/40606216/public/?sort=date&dire
ction=ascending
Original Research Publications
1. Charity B. Breneman, Xuewen Wang, Jan M. Eberth. Community-level determinants of emergency
department utilization among patients with diabetes in South Carolina, 2013. Social Science & Medicine
(in review)
2. Yi-Tzu Kuo*, Arlette C. Perry, Xuewen Wang, Kevin Jacobs, Bobby Robertson. Comparison of body
composition, eating habits, exercise habits, high risk behaviors in a tri-racial group of college female
athletes. Journal of Women’s Health. (in review)
3. Xuewen Wang, Julian Greer, Ryan Porter, Kamaljeet Kaur, Shawn Youngstedt. Short-term moderate
sleep restriction decreases insulin sensitivity in young healthy adults. Sleep Health. Epub 2016 Jan 11.
DOI: 10.1016/j.sleh.2015.11.004
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4. Robin P. Shook*, Gregory A. Hand, Amanda E. Paluch, Xuewen Wang, Robert Moran, James R.
Hebert, John M. Jakicic, Steven N. Blair. High respiratory quotient is associated with increases in body
weight and fat mass in young adults. Eur J Clin Nutr. Epub 2015 Nov 25. Doi: 10.1038/ejcn.2015.198.
5. Xuewen Wang, Tongjian You, Karin Murphy, Mary F. Lyles, Barbara J. Nicklas. Addition of Aerobic
Exercise to Caloric Restriction Increases Adiponectin in Circulation and Release from Adipose Tissue in
Postmenopausal Women. Med Sci Sports Exerc. 2015;47(11):2450-5.
6. Charity B. Breneman, Khosrow Heidari, Sarah Butler, Ryan Porter, Xuewen Wang. Evaluation of the
effectiveness of the H.A.N.D.S.SM program – a school nurse diabetes management training program. J
School Nur. 2015;31(6):402-410
7. Anda Botoseneanu, Walter T. Ambrosius, Daniel P. Beavers, Nathalie de Rekeneire, Stephen Anton,
Timothy Church, Sara C. Folta, Bret H. Goodpaster, Abby C. King, Barbara J. Nicklas, Bonnie Spring,
Xuewen Wang, Thomas M. Gill – for the LIFE Study Group. Prevalence of Metabolic Syndrome and
Its Association with Physical Capacity, Disability, and Self-Rated Health among Lifestyle Interventions
and Independence for Elders (LIFE) Study Participants. J Am Geriatr Soc. 2015; 63(2):222-32.
8. Tongjian You, Xuewen Wang, Karin Murphy, Mary Lyles, Jamehl Demons, Rongze Yang, Da-Wei
Gong, Barbara Nicklas. Regional differences in subcutaneous adipose tissue hormone/cytokine
production before and after weight loss. Obesity. 2014;22(7):1679-84.
9. Robin Shook*, Gregory Hand, Xuewen Wang, Amanda Paluch, Robert Moran, James Hébert,
Damon Swift, Carl Lavie, Steven Blair. Low fitness partially explains differences in resting
metabolic rate between African American and white young adult women. Am J Med. 2014;127:43642.
10. Robin Shook*, Gregory Hand, Amanda Paluch, Xuewen Wang, Robert Moran, James Hébert, Carl
Lavie, Steven Blair. Moderate cardiorespiratory fitness is positively associated with resting
metabolic rate among young adults. Mayo Clin Proc. 2014;89(6):763-71.
11. Xuewen Wang, Shawn Youngstedt. Sleep quality improved following a single session of moderateintensity aerobic exercise in older women. J Sport Health Sci. 2014;3:338-342.
12. Edward Archer*, Gregory Hand, James Hébert, Erica Lau, Xuewen Wang, Robin Shook, Raja
Fayad, Carl Lavie, Steven Blair. Validation of a novel protocol for calculating estimated energy
requirements and average daily physical activity ratio for the US population: 2005-2006. Mayo Clin
Proc. 2013;88(12):1398-1407.
13. Xuewen Wang, Bruce Patterson, Janine Kampelman, Dominic Reeds, Shelby Sullivan, Bettina
Mittendorfer. A ~60-min brisk walk increases insulin-stimulated glucose disposal but has no effect
on hepatic and adipose tissue insulin sensitivity in older women. J Appl Physiol. 2013
Jun;114(11):1563-8.
14. Arlette Perry, Xuewen Wang, Ronald Goldberg, Robert Ross, and Loreto Jackson. Androgenic sex
steroids contribute to metabolic risk beyond intra-abdominal fat in overweight/obese black and white
women. Obesity. 2013;21(8):1618-24.
15. Tongjian You, Xuewen Wang, Rongze Yang, Mary Lyles, Dawei Gong, Barbara Nicklas. Effect of
exercise training intensity on adipose tissue hormone sensitive lipase gene expression in obese
women undergoing weight loss. J Sport Health Sci. 2012;1(3):184-90.
16. Xuewen Wang, Faidon Magkos, Bruce Patterson, Dominic Reeds, Janine Kampelman, Bettina
Mittendorfer. Low-dose dexamethasone administration for 3 weeks favorably affects plasma HDL
concentration and composition but does not affect very low density lipoprotein kinetics. Eur J
Endocrinol. 2012; 167(2):217-23.
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17. Xuewen Wang, Sharina Belani, Daniel Coyne, Elisa Fabbrini, Dominic Reeds, Bruce Patterson,
Bettina Mittendorfer, Samuel Klein. Very low density lipoprotein metabolism in patients with
chronic kidney disease. Cardiorenal Med. 2012 Feb;2(1):57-65.
18. Xuewen Wang, Gordon Smith, Bruce Patterson, Dominic Reeds, Janine Kampelman, Faidon
Magkos, Bettina Mittendorfer. Testosterone administration increases muscle protein synthesis rate
but does not affect very-low-density lipoprotein metabolism in obese premenopausal women. Am J
Physiol Endocrinol Metab. 2012; 302(6):E740-6
19. Xuewen Wang, Fang-Chi Hsu, Scott Isom, Michael Walkup, Stephen Kritchevsky, Bret Goodpaster,
Timothy Church, Marco Pahor, Randall Stafford, Barbara Nicklas. Effects of a 12-month physical
activity intervention on prevalence of metabolic syndrome in elderly men and women. J Gerontol
Med Sci. 2012;67A(4):409-16.
20. Tongjian You, Beth Disanzo, Xuewen Wang, Rongze Yang, Da-Wei Gong. Adipose tissue
endocannabinoid system gene expression: depot differences and effects of diet and exercise. (In
press) Lipids Health Dis. 2011;10:194 Doi: 10.1186/1476-511X-10-194
21. Kristen Beavers, Mary Lyles, Cralen Davis, Xuewen Wang, Daniel Beavers, Barbara Nicklas. Is lost
lean mass from intentional weight loss recovered during weight regain in postmenopausal women?
Am J Clin Nutr. 2011; 94: 767-74. Doi: 10.3945/ajcn.110.004895
22. Tina Brinkley, Xuewen Wang, Noriaki Kume, Hirokazu Mitsuoka, Barbara Nicklas. Caloric
restriction, aerobic exercise training, and soluble lectin-like oxidized LDL receptor-1 levels in
overweight and obese postmenopausal women.
Int J Obes. 2011; 35(6):793-9.
doi:10.1038/ijo.2010.199.
23. Xuewen Wang, Barbara Nicklas. Acute impact of moderate-intensity and vigorous-intensity exercise
bouts on daily physical activity energy expenditure in postmenopausal women. J Obes. Vol 2011;
Article ID 342431. Doi: 10.1155/2011/342431.
24. Arlette Perry, Xuewen Wang, Ronald Goldberg, Robert Ross, Loreto Jackson. Racial disparities
between the sex steroid milieu and the metabolic risk profile. J Obes. Vol. 2010; Article ID 174652,
2010. doi:10.1155/2010/174652.
25. Xuewen Wang, Tongjian You, Rongze Yang, Mary Lyles, Jamehl Demons, Da-Wei Gong, Barbara
Nicklas. Muscle strength is associated with adipose tissue gene expression of inflammatory
adipokines in postmenopausal women. Age Ageing. 2010; 39:656-659.
26. Janet Fulton, Xuewen Wang, Michelle Yore, Susan Carlson, Deborah Galuska, Carl Caspersen.
Television viewing, computer use, and BMI among U.S. children and adolescents. J Phys Act Health.
2009;6(Suppl 1), S28-S35.
27. Xuewen Wang, Tongjian You, Leon Lenchik, Barbara Nicklas. Resting energy expenditure changes
with weight loss: Racial differences.
Obesity.
2010;18(1):86-91. Epub 2009 May 28.
doi:10.1038/oby.2009.163.
28. Xuewen Wang, Arlette Perry, Batya Elbaum, Kent Burnett, Hariharan Swaminathan. Psychometric
properties of a scale to measure menopause-related symptoms in two ethnicities. Climacteric. 2009;
12(4):341-351.
29. Barbara Nicklas, Xuewen Wang, Tongjian You, Mary Lyles, Jamehl Demons, Linda Easter, Michael
Berry, Leon Lenchik, Jeffery Carr. Effect of exercise intensity on abdominal fat loss during caloric
restriction in overweight and obese postmenopausal women: a randomized, controlled trial. Am J
Clin Nutr. 2009; 89(4):1043-52.
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30. Xuewen Wang, Mary Lyles, Tongjian You, Michael Berry, Jack Rejeski, Barbara Nicklas. Weight
regain is related to decreases in physical activity during weight loss. Med Sci Sports Exerc. 2008;
40(10):1781-8.
31. Arlette Perry, Xuewen Wang, Yi-Tzu Kuo. Anthropometric correlates of metabolic syndrome
components in a diverse sample of overweight/obese women. Ethn Dis. 2008; 18(2):163-8.
32. Arlette Perry, Xuewen Wang, Ronald Goldberg, Robert Ross, Loreto Jackson. The relationship
between cardiometabolic and hemostatic variables: influence of race. Metabolism. 2008;57(2):200-6.
33. Xuewen Wang, Gary Miller, Stephen Messier, Barbara Nicklas. Knee strength maintained despite
loss of lean body mass during weight loss in older obese adults with knee osteoarthritis. J Gerontol A
Biol Sci Med Sci. 2007; 62(8): 866-71.
34. Xuewen Wang, Arlette Perry. Metabolic and physiological responses to video game play in 7- to 10year old boys. Arch Pediatr Adolesc Med. 2006; 160 (4): 411-5.
35. Arlette Perry, Evelyn Rosenblatt, Xuewen Wang. Physical, behavioral, and body image
characteristics in a tri-racial group of adolescent girls. Obes Res. 2004; 12(10): 1670-9.
36. Arlette Perry, Xuewen Wang, Brandon Feldman, Tiffany Ruth, Joseph Signorile. Can laboratorybased tennis profiles predict field tests of tennis performance? J Strength Cond Res. 2004; 18(1): 13643.
37. Maria Solano, Arlette Perry, Xuewen Wang, Robert Ross, Ronald Goldberg. Insulin resistance but not
visceral adipose tissue is associated with plasminogen activator inhibitor type 1 levels in overweight and
obese premenopausal African-American women. Int J Obes. 2003; 27 (1): 82-7.
38. Arlette Perry, Tomoki Okuyama, Kijoji Tanaka, Joseph Signorile, Ted Kaplan, Xuewen Wang. A
comparison of health and fitness-related variables in a small sample of children of Japanese descent
on 2 continents. Arch Pediatr Adolesc Med. 2002; 156(4):362-8.
Non-Experimental Articles/ Reviews/ Editorials
39. Xuewen Wang, Faidon Magkos, Bettina Mittendorfer. Sex differences in lipid and lipoprotein
metabolism: it’s not just about sex hormones. J Clin Endocrinol Metab. 2011; 96:885-893.
40. Faidon Magkos, Xuewen Wang, Bettina Mittendorfer. Metabolic actions of insulin in men and
women. Nutrition. 2010; 26:686-93. doi:10.1016/j.nut.2009.10.013
41. Arlette Perry, Xuewen Wang, Yi-Tzu Kuo. Measuring body fat and linking measurements to
metabolic syndrome. Ethn Dis. 2008; 18(2):235.
Other Publications
42. Xuewen Wang. The development of the scale Women’s Health Appraisal to address middle-aged
women’s menopausal symptoms.
Dissertations from ProQuest.
2006; Paper 2494.
http://scholarlyrepository.miami.edu/dissertations/2494.
Conference Presentations/ Abstracts
1. Xuewen Wang, Kimberly P. Bower, Ryan R. Porter, Charity B. Breneman, Sabra Custer, Gregory A.
Hand, Steven N. Blair. Energy expenditure responses to exercise training in older women: a randomized
controlled trial. ACSM 2016, Boston, MA.
2. Joshua R. Sparks, Ryan R. Porter, Charity B. Breneman, Kimberly P. Bowyer, J. Larry Durstine,
Sabra Custer, Xuewen Wang. Increased capacity of work production following a 16-week treadmill
walking protocol in sedentary older women. ACSM 2016, Boston, MA.
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3. Ryan R. Porter, Charity B. Breneman, Kimberly Bowyer, J. Larry Durstine, Sabra Custer, Xuewen
Wang. Relationship between plasma glucose concentration and body composition in older sedentary
women. ACSM 2016, Boston, MA.
4. Xuewen Wang, Kimberly Bower, Ryan Porter, Charity Breneman, Sabra Custer. Aerobic exercise
training reduces postprandial thermogenesis in older women. American Heart Association
Epidemiology/Lifestyle Annual Meeting 2016, Phoenix, AZ.
5. Ryan R. Porter, Charity B. Breneman, J. Larry Durstine, FACSM, Sabra Smith, and Xuewen Wang.
Relationship between plasma concentration and body composition in older sedentary women.
Southeast ACSM 2016.
6. Joshua R. Sparks, Charity B. Breneman, Ryan R. Porter, Kimberly P. Bowyer, Sabra Custer, and
Xuewen Wang. Dose response’s effect on energy efficiency shifts in sedentary older women
following a 16-week treadmill walking protocol. Southeast ACSM 2016
7. Charity B. Breneman, Ryan R. Porter, Kim Bowyer, Sabra Smith, Xuewen Wang. Impact of two
walking interventions on sleep patterns and nightly sleep variability in older women. Southeast
ACSM 2016. (One of the top eight finalists for best poster award)
8. Charity Breneman, Xuewen Wang, Khosrow Heidari, Jan M. Eberth. Neighborhood-level
determinants of emergency department utilization among patients with diabetes in South Carolina,
2015. 21st Annual Diabetes Fall Symposium for Primary Health Care Professionals sponsored by
MUSC, The Diabetes Initiative of South Carolina, South Carolina College of Pharmacy, and
Lowcountry AHEC September 2015. (Second place in the Student Research and Projects category)
9. Ryan R. Porter, Charity B. Breneman, J. Larry Durstine, Kimberly Bowyer, Sabra Smith, and
Xuewen Wang. Effect of exercise dose on hematocrit, hemoglobin concentrations and fitness in
older women. 7th Asia Pacific Conference on Exercise & Sports Science, 2015. (Third place for
Future Leaders Poster Award)
10. Xuewen Wang. Do women need to lose more weight than men to increase circulating adiponectin?
American Physiology Society Conference: Cardiovascular, Renal and Metabolic Diseases:
Physiology and Gender, 2015, Annapolis, MD.
11. Charity B. Breneman, Khosrow Heidari, Xuewen Wang. Greater hospitalization rates for
cardiovascular disease among individuals with diabetes in the state of South Carolina, 2009-2012.
APHA 2015
12. Xuewen Wang, Charity B. Breneman, Kimberly P. Bowyer, Ryan R. Porter, Gregory A. Hand,
Steven N. Blair. Evaluation of SenseWear® Armband to estimate energy expenditure in older
women. International Conference on Ambulatory Monitoring of Physical Activity and Movement
2015, Limerick, Ireland. (Accepted but did not present due to not able to travel)
13. Xuewen Wang, Julian Greer, Ryan Porter, Kamaljeet Kaur, Shawn Youngstedt, Raja Fayad. Shortterm moderate sleep restriction increases insulin concentration following oral glucose tolerance test.
Experimental Biology 2015 (Selected for press release, http://www.newswise.com/articles/morereasons-why-getting-a-good-night-s-sleep-is-important)
14. Xuewen Wang, Ryan R. Porter, Charity B. Breneman, Kimberly P. Bowyer, Sabra Smith, Gregory A.
Hand, Steven N. Blair. Changes in non-exercise activity thermogenesis with participation in exercise
training in older women – preliminary results from the WeWalk study. 2015 Cold Spring Harbor
Laboratory Exercise Science & Health meeting
15. Nicole Gribben*, Robin Shook, Clemens Drenowatz, Xuewen Wang, James Hebert, Greg Hand
FACSM, Steven N. Blair FACSM. Variations of resting metabolic rate by BMI category among
adults. ACSM 2015. San Diego, CA
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16. Ryan R. Porter, Charity Breneman, Kimberly Bowyer, J. Larry Durstine, FACSM, Sabra Smith,
Xuewen Wang. Leg Strength Changes in Sedentary Older Women Following a 16-week Treadmill
Walking Protocol. ACSM 2015. San Diego, CA.
17. Ryan Porter, Charity Breneman, J. Larry Durstine, Sabra Smith, Xuewen Wang. Changes in blood cell
counts in older sedentary women after moderate-intensity aerobic training. Southeastern ACSM 2015
18. Charity Breneman, Ryan Porter, Kimberly Bowyer, Sabra Smith, Xuewen Wang. Differences between
two walking interventions on total and regional body fat in older women. Southeastern ACSM 2015.
19. Tongjian You, Xuewen Wang, Da-Wei Gong. Effects of caloric restriction and aerobic exercise on
adipose tissue AMP-activated protein kinase gene expression in obese older women. American College
of Sports Medicine 2015
20. Julian Greer, Xuewen Wang. The effect of sleep deprivation on glucose metabolism (also known as the
Snooze Control Study). USC Discovery Day 2014. (First Place, Exercise Science & Physical Education
Category)
21. Robin P. Shook*, Gregory A. Hand, Xuewen Wang, Robert Moran, Steven N. Blair. High respiratory
quotient is associated with increases in body weight and fat mass in young adults. American College of
Sports Medicine 2014
22. Katie Becofsky*, Roger Newman-Norlund, Xuewen Wang, Sara Wilcox. Cognitive reserve and fitness
in healthy older women. American College of Sports Medicine 2014
23. Ryan Porter, Charity Breneman, Kimberly Bowyer, J. Larry Durstine, Sabra Smith, Xuewen Wang.
Comparison of Using Heart Rate and VO2 to Estimate Exercise Intensity in Older Women. American
College of Sports Medicine 2014
24. Xuewen Wang, Ryan Porter, Charity Breneman, Kimberly Bowyer, Sabra Smith, Greg Hand, Steven
Blair. Changes in fuel utilization at rest and energy expenditure with aerobic training in older women.
American College of Sports Medicine 2014
25. Charity Breneman, Ryan Porter, Imran Iftikhar, Sabra Smith, Xuewen Wang. The relationship between
aerobic fitness and physical activity with sleep characteristics in sedentary older women. American
College of Sports Medicine 2014
26. Tongjian You, Xuewen Wang, Barbara J. Nicklas. Effects of exercise intensity on prevalence of
metabolic syndrome in obese older women during caloric restriction. American College of Sports
Medicine 2014
27. Ryan Porter, Charity Breneman, J. Larry Durstine, Sabra Smith, Xuewen Wang. Changes in blood cell
counts in older sedentary women after moderate-intensity aerobic training. Southeastern American
College of Sports Medicine 2014
28. Charity Breneman, Ryan Porter, Imran Iftikhar, Sabra Smith, Xuewen Wang. The relationship between
aerobic fitness and sleep characteristics in sedentary older women: baseline data from the WeWalk study.
Southeastern American College of Sports Medicine 2014. (Doctoral student research award finalist)
29. Charity Breneman, Khorsrow Heidari, Sarah Butler, Ryan Porter, Xuewen Wang. Evaluation of the
effectiveness of the H.A.N.D.S. program – a School Nurse Diabetes Management Training Program.
Diabetes Fall Symposium for Primary Health Care Professionals 2013, North Charleston, SC. (Third
place in Student/Fellow/Resident research category)
30. Xuewen Wang, Tongjian You, Mary F. Lyles, Karin Murphy, Barbara J. Nicklas. Addition of exercise
to caloric restriction increases adiponectin concentration and release from gluteal and abdominal adipose
tissue in obese/overweight postmenopausal women. The Obesity Society 2013. (Selected for conference
media coverage)
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31. Arlette Perry, Xuewen Wang, Ronald Goldberg, Robert Ross, Loreto Jackson, Christopher Bailey.
Androgenic sex steroids contribute to metabolic risk beyond intra-abdominal fat in overweight/obese
black and white women. The Obesity Society 2013.
32. Tongjian You, Xuewen Wang, Rongze Yang, Dawei Gong, Mary Lyles, and Barbara Nicklas. Effects
of Weight Loss on Subcutaneous Adipose Tissue Hormone/Cytokine Production: Depot Comparisons.
ACSM 2013. (Selected as one of the top basic science posters)
33. Robin Shook*, Amanda Paluch, Greg Hand, Xuewen Wang, Steven Blair. Resting metabolic rate,
cardiorespiratory fitness, and racial differences in adiposity among adult women. American Heart
Association the 53rd Cardiovascular Disease Epidemiology and Prevention, and Nutrition, Physical
Activity and Metabolism Conference, New Orleans, 2013.
34. Xuewen Wang, Shawn Youngstedt. Improvements in Sleep Quality Following Moderate, but Not
Light-Intensity Acute Aerobic Exercise in Older Women. American Heart Association the 53rd
Cardiovascular Disease Epidemiology and Prevention, and Nutrition, Physical Activity and Metabolism
Conference, New Orleans, 2013.
35. Xuewen Wang, Bruce Patterson, Janine Kampelman, Dominic Reeds, Shelby Sullivan, Bettina
Mittendorfer. A single session of moderate-intensity aerobic exercise improves muscle insulin sensitivity
in older women. University of South Carolina Women’s Health Forum, 2012.
36. Xuewen Wang, Bruce Patterson, Janine Kampelman, Dominic Reeds, Shelby Sullivan, Bettina
Mittendorfer. A single session of moderate-intensity aerobic exercise improves muscle insulin sensitivity
in older women. Med Sci Sport Exerc. 2012; 44(5s):102. (Thematic poster).
37. Xuewen Wang, Bruce Patterson, Dominic Reeds, Bettina Mittendorfer. Lipid metabolism response to 3
weeks of testosterone treatment in obese premenopausal women. The 7th Annual Interdisciplinary
Women’s Health Research Symposium, 2010. NIH Office of Research on Women’s Health.
38. Xuewen Wang, Bruce Patterson, Dominic Reeds, Bettina Mittendorfer. Lipid metabolism response to 3
weeks of testosterone treatment in obese premenopausal women. Endocr Rev. June 2010; 31(3): S2112.
39. Tongjian You, Beth Disanzo, Xuewen Wang, Rongze Yang, Da-wei Gong, Barbara Nicklas. Adipose
tissue endocannabinoid system: depot differences and effects of diet and exercise. Med Sci Sport Exerc.
2010; 42(5s):p519.
40. Xuewen Wang, Fang-Chi Hsu, Bret Goodpaster, Timothy Church, Marco Pahor, Barbara Nicklas.
Effects of a 12-month physical activity intervention on prevalence of metabolic syndrome in elderly men
and women. American Heart Association Cardiovascular Disease Epidemiology and Prevention, and
Nutrition, Physical Activity and Metabolism Joint Conference 2010.
41. Eduard Tiozzo, Arlette Perry, Xuewen Wang, Ronald Goldberg, Robert Ross, Loreto Jackson. Do sex
steroids contribute significant information above central obesity in the prediction of metabolic risk? Med
Sci Sports Exerc. 2009 (5 supple): S495.
42. Tongjian You, Xuewen Wang, Rongze Yang, Wan Shen, Dawei Gong, Barbara Nicklas. Effect of
exercise training on adipose tissue lipoprotein lipase gene expression in obese women undergoing weight
loss. Med Sci Sports Exerc. 2009 (5 supple): S28.
43. Xuewen Wang, Tongjian You, Leon Lenchik, Barbara Nicklas. Resting energy expenditure changes
with weight loss: racial differences. Med Sci Sports Exerc. 2009 (5 supple.): S87.
44. Barbara Nicklas, Gary Miller, Cralen Davis, Xuewen Wang, Claudine Legault, Stephen Messier.
Relationship of daily physical activity to physical function in older, overweight and obese men and
women with knee osteoarthritis. J Am Geriatr Soc. 2009; 57 (3 Suppl).
45. Tina Brinkley, Xuewen Wang, Noriaki Kume, Barbara Nicklas. Weight loss reduces plasma soluble
Wang, Xuewen
January 2016
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lectin-like oxidized LDL receptor-1 levels in overweight and obese women. American Heart Association
Cardiovascular Disease Epidemiology and Prevention, and Nutrition, Physical Activity and Metabolism
Joint Conference 2009.
46. Mary Lyles, Xuewen Wang, Barbara Nicklas. Changes in weight and body composition 12 months
following completion of a weight loss intervention. The Obesity Society Annual Meeting 2008.
47. Barbara Nicklas, Xuewen Wang, Tongjian You, Mary Lyles, Jamehl Demons. Effect of aerobic
exercise intensity on loss of visceral fat and improvement in metabolic risk factors in women. American
Diabetes Association 2008.
48. Mary Lyles, Xuewen Wang, Jamehl Demons, Barbara Nicklas. Functional consequences of weight
regain: Changes 6 months after a successful weight loss intervention. J Am Geriatr Soc. 2008; 56(S1).
49. Xuewen Wang, Mary Lyles, Tongjian You, Michael Berry, Jack Rejeski, Barbara Nicklas. Weight
regain is related to adaptations in physical activity energy expenditure during weight loss. American
Heart Association Cardiovascular Disease Epidemiology and Prevention, and Nutrition, Physical
Activity and Metabolism Joint Conference 2008.
50. Tongjian You, Adolfo Fernandez, Xuewen Wang, Barbara Nicklas, Gary Miller. Physical function is
not related to abdominal adipose tissue cytokine release in morbid obesity. Med Sci Sport Exerc. 2008;
40: 1910.
51. Barbara Nicklas, Xuewen Wang, Mary Lyles, Jamehl Demons. Changes in physical performance with
weight loss and exercise are associated with selective loss of ectopic fat in postmenopausal women.
Gerontological Society of America Annual Meeting 2007.
52. Tongjian You, Xuewen Wang, Mary Lyles, Jamehl Demons, Barbara Nicklas. Inflammatory proteins
released by abdominal and gluteal subcutaneous adipose tissue: Regional differences and relationships
with metabolic risk factors. The Obesity Society Annual Scientific Meeting 2007.
53. Barbara Nicklas, Linder Easter, Tongjian You, Xuewen Wang, Mary Lyles. Degree of caloric
restriction and improvement in glucose metabolism and insulin sensitivity in older, postmenopausal
women undergoing weight loss. American Diabetes Association Annual Meeting 2007.
54. Xuewen Wang, Tongjian You, Mary Lyles, Jamehl Demons, Barbara Nicklas. Adipose tissue
production of inflammatory mediators is related to aerobic fitness and muscle strength in obese
postmenopausal women. Med Sci Sports Exerc. 2007; 39 (5): S68.
55. Jamehl Demons, Xuewen Wang, Mary Lyles, Steve Kritchevsky, Barbara Nicklas. Effects of weight
loss on physical performance in obese postmenopausal women. J Am Geriatr Soc. 2007; 55(s1):164.
56. Mary Lyles, Xuewen Wang, Tongjian You, Leon Lenchik, Jamehl Demons, Barbara Nicklas. Changes
in weight and body composition 12 months following completion of a weight loss intervention. J Am
Geriatr Soc. 2007; 55(s1):165-6.
57. Barbara Nicklas, Tongjian You, Mary Lyles, Jamehl Demons, Xuewen Wang. Weight loss via caloric
restriction and aerobic exercise reduces prevalence of metabolic syndrome in older, obese women. The
Gerontologist. 2006; 46(1):550.
58. Arlette Perry, Xuewen Wang. Anthropometric correlates of metabolic and cardiovascular variables
associated with health risk in a tri-racial sample of overweight/obese women. Obesity. 2006; 14 (9
Supple): A110.
59. Xuewen Wang, Gary Miller, Stephen Messier, Barbara Nicklas. Knee strength maintained despite loss
of muscle mass during intensive weight loss in older obese adults. Obesity. 2006; 14 (9 Supple): A43.
(Selected for conference media coverage)
60. Xuewen Wang, Tongjian You, Justin Johnson, Eulonda Paraway, Michael Berry, Barbara Nicklas.
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January 2016
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Physical activity energy expenditure decreases during a 5-month calorie deficit diet in obese,
postmenopausal women. Med Sci Sports Exerc. 2006; 38 (5 suppl): S14.
61. Xuewen Wang, Arlette Perry. Does age of menopause predict risk factors associated with
cardiovascular metabolic diseases? Obes Res. 2005; 13 (9 Suppl): A94.
62. Xuewen Wang, Arlette Perry, Ronald Goldberg, Robert Ross. Abdominal subcutaneous adipose tissue
predicts health risk variables in premenopausal women: racial differences. Obes Res. 2004; 12 (10
Suppl): A137.
63. Janet Fulton, Xuewen Wang, Michelle Yore, Deborah Galuska, Carl Caspersen. Television viewing and
computer use among U.S. children and adolescents. The 8th International Congress of Behavioral
Medicine, 2004.
64. Evelyn Rosenblatt, Arlette Perry, Xuewen Wang, Gregory Bigford. A comparison of physical activity,
adiposity, nutrient intake, and body image among a tri-racial population of adolescent females. Obes
Res. 2003; 11(9 Suppl): A102.
65. Arlette Perry, Xuewen Wang, Loreto Jackson. Can sex steroids enhance the prediction of health-related
variables above waist circumference in premenopausal women? Obes Res. 2003; 11(9 Suppl): A65.
66. Xuewen Wang, Arlette Perry, Loreto Jackson. Racial differences of predicting health-related variables
using total testosterone, sex hormone-binding globulin, and free androgen index in premenopausal
women. Obes Res. 2003; 11(9 Suppl): A57.
67. Xuewen Wang, Gregory Bigford, Arlette Perry. Age and menstrual status: effects on central obesity
and health related variables in overweight women. Med Sci Sports Exerc. 2003; 35(5):S12.
68. Xuewen Wang, Arlette Perry, Loreto Jackson. Can sex steroids enhance the prediction of health-related
variables above waist circumference? Annual Eastern-Atlantic Student Research Forum, 2003.
69. Angie Van Bemden, Xuewen Wang, Arlette Perry. Anthropometric indices of body fat distribution
and health related variables in a tri-ethnic group of women. Med Sci Sports Exerc. 2002; 34(5): S107.
70. Arlette Perry, Xuewen Wang, Loreto Jackson, Robert Ross. Is intra-abdominal fat a marker of
metabolic risk in overweight Caucasian and African-American women? Med Sci Sports Exerc. 2002;
34(5): S107.
71. Xuewen Wang, Arlette Perry, Ronald Goldberg, Loreto Jackson, Robert Ross, Steven Deprima.
Differences of clotting factors in predicting health-related variables in Caucasian and African-American
women. Med Sci Sports Exerc. 2002; 34(5): S168.
72. Maria Solano, Arlette Perry, Xuewen Wang, Ronald Goldberg. Ethnic differences in the relationship
between PAI-1 and metabolic components of the insulin resistance syndrome in obese premenopausal
women. Scientific Session of the American Diabetes Association, 2001.
73. Xuewen Wang, Maria Solano, Arlette Perry, Ronald Goldberg. Racial differences of clotting factors in
predicting health-related variables. American Diabetes Association Research Symposium, 2000.
Underlined names are student first authors that I have directly mentored. Underlined names* are student first
authors whose research I have been involved with.
RESEARCH SUPPORT
Ongoing Research Support
American Heart Association 14BGIA20380706
Wang, Xuewen
January 2016
Wang (PI)
7/01/14-6/30/16
$154,000
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Effects of sleep restriction on body composition and energy expenditure during dietary weight loss
The objective of this proposed study is to compare body composition and components of energy
expenditure after two interventions: caloric restriction alone vs. caloric restriction combined with sleep
restriction, for 8 weeks in obese adults.
NIH/NIA R00AG031297
Wang (PI)
6/15/12-5/31/15
Energy expenditure responses to acute and chronic exercise in older women
$711,904
The goal of the R00 phase of this K99/R00 Pathway to Independence (PI) award is to determine whether
older women experience greater energy expenditure compensation in response to higher-dose vs. lowerdose chronic exercise.
Past Research Support
USC Magellan Scholar Award
Wang (PI), Greer (Co-PI)
The effect of sleep deprivation on glucose metabolism
1/1/14-12/31/14
$2,000
This pilot project will examine the effect of sleep duration on glucose metabolism by observing
concentrations of glucose, insulin and other factors involved in glucose metabolism after shortened sleep
during the week and after recovery with sufficient sleep during the weekend using oral glucose tolerance
tests in young adults.
USC Magellan Mini-Grant
Greer (PI)
The effect of sleep deprivation on glucose metabolism
12/2/13-12/15/14
$1,000
The Megellan Mini-Grant provides funds for an undergraduate student to work on a research project.
Role: Mentor
USC Magellan Apprentice
Greer (PI)
The effect of sleep deprivation on glucose metabolism
12/2/13-12/15/14
$700
The Megellan Apprentice provides additional funds for an undergraduate student to work on a research
project.
Role: Mentor
NIH P50 HD057796
Ehrmann (Project Director); Mittendorfer (Project PI)
Sex hormones, sleep and metabolic dysfunction in women
06/01/08-12/31/12
The main purpose of this program project was to evaluate the effects of polycystic ovary syndrome and
obstructive sleep apnea on triglyceride metabolism and the control of lipid metabolism by sex hormones
and glucocorticoids. Very-low-density lipoprotein kinetics was quantified using stable isotope tracers and
compartmental modeling.
Role: Co-Investigator, lead and conduct the study and prepare publications
NIH K99 AG031297
Wang (PI)
09/15/09-8/31/12
Energy expenditure responses to acute and chronic exercise in older women
The goal of the K99 phase is to determine whether energy expenditure responses to acute energy balance
challenges--induced by two separate bouts of aerobic exercise at two different intensities--are different in
older women. A secondary goal is to determine whether an acute bout of aerobic exercise improves
multi-organ insulin sensitivity (i.e., suppression of hepatic glucose production, stimulation of muscle
glucose uptake, suppression of adipose tissue lipolysis) assessed by hyperinsulinemic-euglycemic clamp
procedure in conjunction with stable isotope tracers.
Wang, Xuewen
January 2016
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Washington University ICTS JIT1135
Wang (PI)
Energy expenditure responses to acute exercise in older women
07/21/10-07/20/11
The Institute of Clinical and Translational Sciences (ICTS) provided funding for laboratory-based
biochemical assays needed to complete the NIH K99 project.
American Heart Association 0885048N
Wang (PI)
07/01/08-6/30/10
Effects of exercise training on prevalence of metabolic syndrome in the elderly
The Lifestyle Interventions and Independence for Elders Pilot (LIFE-P) study is a multi-site, singleblinded, randomized, controlled clinical trial that compared a 12-month physical activity intervention with
a non-exercise successful aging health education intervention in 424 elderly (70-89 years), nondisabled,
community-dwelling men and women at risk for physical disability. This project was an ancillary to the
LIFE-P study that determined whether a physical activity intervention decreased the prevalence and
severity of the metabolic syndrome more than the non-exercise health education intervention.
Wake Forest University GCRC 0450
Wang (PI)
03/2007-06/2008
Aging-related differences in energy expenditure in response to acute exercise
This pilot study refined the existing energy expenditure assessment protocols and gathered preliminary
data that were used for a research grant submission.
NIH R01 AR052528
Messier (PI)
Intensive dietary restriction with exercise in arthritis
08/01/06-05/31/08
This study compared the effects of dietary restriction-plus-exercise, exercise-only, or dietary restrictiononly on inflammatory biomarkers and knee joint loads in obese older adults with knee osteoarthritis.
Role: Co-Investigator, conduct physical activity measurements including energy expenditure and activity
pattern
NIH R01 AG/DK20583
Nicklas (PI)
Exercise and regional fat metabolism after menopause
09/01/05-05/31/08
This study determined the cellular mechanisms by which exercise intensity affected the loss of abdominal,
compared to gluteal, adipose tissue under conditions of equal energy deficit in postmenopausal women
with abdominal obesity.
Role: Co-Investigator, oversee exercise intervention, conduct physical activity and resting energy
expenditure measurements, perform laboratory experiments involving human subcutaneous adipose tissue,
manage database
Applied but Not Funded
Grape (LOI)
Wang (PI)
Submitted 12/2015
Effect of grape powder on inflammation, insulin sensitivity, and β-cell function in prediabetic humans
Not invited for full application
COBRE
Wang (PI)
submitted 05/2015
Effects of quercetin supplementation on inflammation, insulin sensitivity and β-cell function in
prediabetic humans
Wang, Xuewen
January 2016
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The goal of this pilot study is to provide preliminary data and effect estimates to begin testing our overall
hypothesis that quercetin delays the development of type 2 diabetes by reducing inflammation.
NIH/NIA R01AG
Wang (PI)
12/01/15-11/33/20
Exercise training, energy expenditure and body composition in older adults
$3,030,725
The goal of this project is to obtain information on energy expenditure, sedentary behavior, and body
composition in order to understand the adaptive changes that occur in response to aerobic exercise with
and without resistance exercise training in older adults. Impact Score 46; Percentile 31%
NIH/NIA R01AG
Wang (PI)
Exercise training, energy expenditure and body composition in older adults
04/01/15-03/31/20
The goal of this project is to obtain important information on energy expenditure, energy intake, and body
composition in order to understand the adaptive changes that occur in response to aerobic exercise with
and without resistance exercise training in older adults. Resubmitted
American Federation for Aging Research A14086
Wang (PI)
Effects of exercise on adipose tissue inflammation in the elderly
07/01/14-12/31/15
The objective of this proposed study is to investigate whether exercise alone without dietary restriction
affects adipose tissue inflammation, including the production of inflammatory mediators and
macrophage’s phenotype modulation and their chemokine production.
University of South Carolina Office of the Vice President for Research Advanced Support Program for
Innovative Research Excellence-I (ASPIRE-I) Wang (PI)
05/16/13-09/15/14
Effects of sleep restriction and shifted schedule on insulin sensitivity
The objectives of this proposed study are to compare insulin sensitivity following habitual sleep and
restricted and irregular sleep in non-obese healthy young adults, and to refine the methods of intravenous
glucose tolerance test and 5-hour oral glucose tolerance test to determine insulin sensitivity at USC.
This proposal was later simplified and received USC Magellan awards.
NIH R21HL120039
Wang (PI)
07/01/13 – 06/31/15
Chronic moderate sleep restriction and irregular sleep: effects on energy balance
The objective of this proposed study is to compare the effects of chronic moderate sleep restriction alone
and combined with irregular timing of sleep on components of energy expenditure and energy intake in
overweight or obese young adults.
South Carolina Clinical & Translational Research Institute (SCTR) Discovery Pilot Project preapplication 2013
Wang (PI)
Submitted 05/2013
one year
$25,000
Effects of protein supplement and resistance training during weight loss in elderly men
The objective of this proposed study is to determine the effects of supplementary protein intake and
resistance exercise training, in the presence of caloric restriction, on physical function and metabolic
health in obese (body mass index > 30 kg/m2) elderly (65-80 years) men. Not invited for full application.
Wang, Xuewen
January 2016
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Clinical and Translational Research Funding Program, Barnes-Jewish Hospital Foundation & Washington
University Institute of Clinical and Translational Sciences
Wang (PI)
06/01/10-5/31/12
Sleep disordered breathing and physical function in elderly men
This study evaluates whether sleep disordered breathing is associated with reduced muscle mass and
diminished physical function in older adults.
Pending
NIH/NIA R01AG
Wang (PI)
12/01/15-11/33/20
$3,030,725
Exercise-induced changes in energy expenditure in older adults and potential role of inflammatory
changes
The major goal of the proposed study is to determine quantitatively the changes in energy expenditure
(EE), sedentary behavior, and body composition that occur in older adults in response to 6 months of
aerobic exercise with and without resistance exercise training, and to examine whether exercise-induced
inflammatory changes play a mechanistic role in any adaptive changes in thermogenesis.
Veterans Affairs
Autonomic Blunting and Restoration in Veterans with Gulf War Syndrome: The Heart Rate Variability
Index of Cognitive Performance, Fatigue, and Rest/Activity
Sub-contract with the Dorn Research Institute
Role: subcontract investigator
PI: Ginsberg; Subcontract PI: Carson
Wang, Xuewen
January 2016
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