© Copyright 2002 Nelson Thomson Learning interphase The cell replicates its DNA and prepares for nuclear division. In humans, each of the 46 chromosomes duplicates itself. The result is 46 duplicated chromosomes, or 46 pairs of chromatids. early prophase The chromosomes condense, becoming shorter and thicker. The centrioles move to opposite poles of the cell and spindle fibres start to form. late prophase Chromosomes continue to condense. The centrioles assemble and spindle fibres attach to the centromeres of the chromosomes. The nuclear membrane starts to dissolve. Mitosis in an Animal Cell 3.2 interphase telophase Chromosomes lengthen again, the spindle fibres dissolve, and a nuclear membrane forms around the chromosomes. In humans, each new nucleus contains 46 unique chromosomes. anaphase The centromeres divide and the resulting chromosomes, formerly chromatids, move to opposite poles of the cell. An identical set of chromosomes moves to each pole. Biology 11, page 88–89, Figure 4 19 metaphase Chromosomes line up at the equatorial plate. The nuclear membrane completely dissolves. Nelson Biology 11