5th Annual Brain Tumor Symposium PAID PERMIT NO. #117 SOUTHEASTERN, PA 19399 The New Revolution in Neuro-Oncology: Molecular Diagnoses and Targeted Treatments NON-PROFIT ORG U.S. POSTAGE 5th Annual Brain Tumor Symposium Friday, October 30, 2015 | DoubleTree by Hilton Hotel Philadelphia Center City 237 South Broad Street, Philadelphia, PA 19107 The New Revolution in Neuro-Oncology: Molecular Diagnoses and Targeted Treatments Registration Fees Practicing Physician $165 Nurse / Nurse Practitioner $140 Allied Health Professional $140 Jefferson Affiliate Hospitals - Practicing Physician $125 Jefferson Affiliate Hospitals - Nurse / Allied Health Professional $105 Non-Jefferson Resident $100 Non-Jefferson Fellow $100 ATION REGISTR N OW ! OPEN The registration fee includes all course materials, access to presentations online, CE certificate, breakfast, refreshment breaks and lunch. The registration fee does not include parking. HOME CME ACTIVITIES | Sidney Kimmel Medical College RSS/GRAND ROUNDS LEARNING GROUPS CREDIT HISTORY CONTACT US *Registration Deadline is: October 28, 2015* Registrations should be submitted online by this date. Registrations cannot be processed without payment. Should you need additional assistance or if you have any special needs, please contact the Office of CME at 215-955-6992 or via email at jeffersoncme@Jefferson.edu. Paper registration available upon request. Department of Neurological Surgery As an integral part of Jefferson Hospital for Neuroscience, the region’s only dedicated hospital for neuroscience, the Department of Neurological Surgery is one of the busiest academic neurosurgical programs in the country, offering state-of-the-art treatment to patients with neurological diseases affecting the brain and spine, such as brain tumors, spinal disease, vascular brain diseases, epilepsy, pain, Parkinson’s disease and many other neurological disorders. Jefferson.edu/university/jmc/departments/neurosurgery.html Registration Now Open! Thomas Jefferson University Register Office of Continuing Medical Education 1020 Locust Street, Suite M-5 Philadelphia, PA 19107 Log in Have a smart phone? Go to scanlife.com to download your free QR code reader Step #2 – Once you are logged in, you may register for this conference by clicking the “CME Activities” tab located on the top of the page, and clicking on the activity name “5th Annual Brain Tumor Symposium”. • Review the course webpage, and scroll down to see the registration options. • Complete the online registration process. • You will receive a confirmation email of your successful registration. • If you are unable to attend, cancellation fees may be applied. Please refer to the Cancellation/Refund Policy located on the course webpage at CME.Jefferson.edu. Friday, October 30, 2015 Step #1 – Login to your account on CPD@JeffLearn™ at CME.Jefferson.edu. • If you do not have an account, step by step instructions can be found on the CPD@JeffLearn™ webpage. • Click “Login” if you have an account. Click “Register” to create an account The New Revolution in Neuro-Oncology: Molecular Diagnoses and Targeted Treatments Important Browser Information – site works best on Google CHROME, Mozilla FIREFOX, SAFARI or OPERA. Please be sure you are running the most recent version of your browser. 5th Annual Brain Tumor Symposium Here’s How to Register Online Today at CME.Jefferson.edu: Friday, October 30, 2015 DoubleTree by Hilton Hotel Philadelphia Center City Featured Guest Speakers Tracy T. Batchelor, MD, MPH Jason T. Huse, MD, PhD Frederick F. Lang, Jr, MD, FACS, FAANS 5th Annual Brain Tumor Symposium The New Revolution in Neuro-Oncology: Molecular Diagnoses and Targeted Treatments Friday, October 30, 2015 | DoubleTree by Hilton Hotel Philadelphia Center City 237 South Broad Street, Philadelphia, PA 19107 Course Description This CME Conference offers participants a unique opportunity to hear expert clinician leaders relate their knowledge of the field of neuro-oncology and current state-of-the-art advances. Cases will be examined from multiple perspectives, providing participants with clinical pearls for diagnosing and managing malignant brain tumors to improve patient outcomes. The course will feature: • M orning lectures devoted to the theme of the symposium: new research initiatives that highlight the dramatic advances in both diagnosis and treatment of malignant brain tumors. Friday, October 30, 2015 (Preliminary Agenda/Subject to Change) 7:00AMRegistration, Continental Breakfast, and Exhibits 7:45AMWelcome & Introduction of Keynote Speakers David W. Andrews, MD, FACS Lyndon J. Kim, MD 8:00AM Keynote Lecture: Exploiting Viruses and Stem Cells for Glioma Therapy Frederick F. Lang, Jr, MD, FACS, FAANS Introduction: Kevin D. Judy, MD, FACS 8:40AM • A fternoon, profession-specific break-out sessions, providing additional opportunities for focused discussions and interactions. Each session will be designed to give practitioners updates in the latest trends and advances in neuro-oncology and learning will be reinforced through lively interactive case-based discussion. Lectures will also provide practitioners with updates in ongoing clinical trials at Jefferson as well as current outpatient brain tumor management. Educational Design At the conclusion of this conference, participants should be able to: Examine how viruses work and how they can be engineered for glioma therapy. Describe how molecular markers refine the diagnosis and management of diffuse glioma and evaluate their impact on both prognosis and treatment. Assess the plight of orphan diseases and the challenges of establishing evidence-based treatment data for small patient populations. Appraise the literature and the WHO Classification System for common brain tumors and cite sources where new knowledge has modified or changed the classification of certain tumors. Recognize how molecular markers refine the diagnosis and management of brain metastases Summarize the history of human experimentation from systemic cancers and evaluate their spanning from the mid-20th century to the impact on both prognosis and treatment. present and draw conclusions about evolution of FDA regulations for human research. Review and critique current treatment strategies for CNS lymphoma and evaluate the Evaluate current clinical trials at Jefferson as it metrics for establishing a cure for this disease. relates to patient centric care and validate the process for enrollment criteria for each trial. Examine how the current standard of care treatment negatively impacts the immune system Differentiate various radiation treatment methods and how this might influence an immunotherapy currently utilized for benign and malignant treatment for recurrent glioma treatment. disease and evaluate patient centric care needs, both during and after radiation therapy. Analyze the challenging anatomy of the sellar region and appreciate how recent innovations Analyze the detailed nature of outpatient care in treatment and outcomes have improved of brain tumor patients and identify the tools to patient care. determine the individual needs of patients and families, particularly during treatment. Appraise the methodology and technology of new fiberoptic laser technology and its Assess their individual practice in light of the application to challenging lesions such as information and discussions during the course, “butterfly” gliomas. and identify specific strategies to implement as part of a continuing improvement process for their practices. eynote Lecture: The Evolving Role of K Molecular Markers in the Diagnosis and Management of Diffuse Gliomas Jason T. Huse, MD, PhD Keynote Lecture: Targeted Therapeutics for Gliomas Tracy T. Batchelor, MD, MPH Introduction: Lyndon J. Kim, MD 9:20AM 10:00AMBreak & Exhibits 10:20AMUpdate for IND 14379-101: Immunotherapy Trial for Recurrent Glioma David W. Andrews, MD, FACS 10:50AMChemotherapy Redux: Resurrecting PCV Chemotherapy for Oligodendroglioma Jon Glass, MD 1:45PMApplication of Fiber-Optic Laser to Malignant Intracranial Disease Kevin D. Judy, MD, FACS 2:15PMReview of New Protocols for Craniopharyngioma and WHO Grade II Meningioma Christopher J. Farrell, MD 3:00PMUtilization of Molecular Genetic Profiling Test to Individualize Chemotherapy Treatment Lyndon J. Kim, MD 3:30PMAnticipating the 2016 WHO Fascicle on Brain Tumors: An Update Lawrence C. Kenyon, MD, PhD Nurse And Allied Health Professional Track: Updates From Jefferson Nurses ORCHESTRA BALLROOM 1:15PMWhen is a Novel Treatment Innovative and When is it Experimental? Catherine Harris, PhD, MBA, CRNP 1:45PMUpdate on Current Clinical Neuro-Oncology Trials at Jefferson Lauren Barbieri, CRNP 1:15PM Break/Move to Breakout Session 3:30PMInteractive Discussion: Case Presentations Two Afternoon Break-Out Sessions: Practicing and Question/Answer Physician Track and Nurses/Allied Health Moderator: Lauren Barbieri, CRNP Professionals Track. All attendees will re-convene Panelists: S akinah Abdulkhabir, RN, BSN after the afternoon break-out sessions for the Catherine Harris, PhD, MBA, CRNP Closing Remarks in the Symphony Ballroom. Gail Williams, DNP, CRNP, AOCNP SYMPHONY BALLROOM David W. Andrews, MD, FACS James J. Evans, MD, FACS Professor of Neurological Surgery Vice Chair, Clinical Services Department of Neurological Surgery Division Chief, Division of Neuro-Oncology Professor of Neurological Surgery and Otolaryngology – Head and Neck Surgery Director, Cranial Base and Pituitary Surgery Co-Director, Jefferson Center for Minimally Invasive Cranial Base and Endoscopic Neurosurgery Lauren Barbieri, CRNP Nurse Practitioner Department of Neurological Surgery FINAL PLENARY SESSION 4:00PMClosing Remarks David W. Andrews, MD, FACS 1:15PMUpdate in Minimally Invasive Cranial Base Surgery James J. Evans, MD, FACS For additional information please visit CME.Jefferson.edu Kevin D. Judy, MD, FACS Professor of Neurological Surgery Section Chief, Surgical Neuro-Oncology Guest Faculty 2:45PMBreak & Exhibits 2:15PMRadiation Therapy WBRT/SRS: Nursing Overview of the Radiation Treatment 11:20AMPanel of Invited Speakers: A Discussion of Methods for Brain Tumors Selected Cases from the Faculty Gail Williams, DNP, CRNP, AOCNP Moderator: David W. Andrews, MD, FACS Panelists: T racy T. Batchelor, MD, MPH 2:45PMBreak & Exhibits Jason T. Huse, MD, PhD Frederick F. Lang, Jr, MD, FACS, FAANS 3:00PMNursing Management of Patients with Brain Tumors in Ambulatory Care 12:30PM Lunch & Exhibits Sakinah Abdulkhabir, RN, BSN Practicing Physician Track: Updates From Jefferson Physicians Sidney Kimmel Medical College Course Directors Tracy T. Batchelor, MD, MPH Giovanni Armenise - Harvard Professor of Neurology, Harvard Medical School Executive Director, Stephen E. and Catherine Pappas Center for Neuro-Oncology, Massachusetts General Hospital Boston, Massachusetts Jason T. Huse, MD, PhD Assistant Member, Department of Pathology and Human Oncology and Pathogenis Program Memorial Sloan-Kettering Cancer Center New York, New York Frederick F. Lang, Jr, MD, FACS, FAANS Professor of Neurosurgery Director of Clinical Research, Department of Neurosurgery, Division of Surgery The University of Texas MD Anderson Cancer Center Houston, TX Sidney Kimmel Medical College Faculty Sakinah Abdulkhabir, RN, BSN Lawrence Kenyon, MD, PhD Nurse, Department of Neurological Surgery Associate Professor of Pathology, Anatomy, Cell Biology, and Neurology Christopher Farrell, MD Associate Professor of Neurological Surgery Lyndon Kim, MD Jon Glass, MD Associate Professor of Medical Oncology and Neurological Surgery Associate Professor of Neurology and Neurological Surgery Catherine Harris, PhD, MBA, CRNP Assistant Professor, Graduate Program Jefferson College of Nursing Gail Williams DNP, CRNP, AOCNP Nurse Practitioner, Department of Neurological Surgery For more information, please visit the course web page: CME.Jefferson.edu ACCREDITATION INFORMATION PHYSICIANS: Sidney Kimmel Medical College at Thomas Jefferson University is accredited by the ACCME to provide continuing medical education for physicians. Sidney Kimmel Medical College designates this live activity for a maximum of 6.75 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. NURSES: Thomas Jefferson University Hospital is an approved provider of continuing nursing education by the PA State Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. A maximum of 6.66 contact hours will be awarded to participants. PHYSICIAN ASSISTANTS: The American Academy of Physician Assistants accepts AMA PRA Category 1 Credit(s)™ (www.aapa.org). FACULTY DISCLOSURE All faculty participating in continuing medical education activities sponsored by Sidney Kimmel Medical College at Thomas Jefferson University are expected to disclose to the activity audience any real or apparent conflict(s) of interest related to the content of their presentation(s). Full disclosure of faculty relationships will be made at the activity. HOTEL ACCOMMODATIONS Please visit the course web page for hotel accommodation information. In keeping with Jefferson’s integrated approach to education and care, this Symposium is organized through the collaborative efforts of Jefferson’s Sidney Kimmel Cancer Center, and Sidney Kimmel Medical College at Thomas Jefferson University. 5th Annual Brain Tumor Symposium The New Revolution in Neuro-Oncology: Molecular Diagnoses and Targeted Treatments Friday, October 30, 2015 | DoubleTree by Hilton Hotel Philadelphia Center City 237 South Broad Street, Philadelphia, PA 19107 Course Description This CME Conference offers participants a unique opportunity to hear expert clinician leaders relate their knowledge of the field of neuro-oncology and current state-of-the-art advances. Cases will be examined from multiple perspectives, providing participants with clinical pearls for diagnosing and managing malignant brain tumors to improve patient outcomes. The course will feature: • M orning lectures devoted to the theme of the symposium: new research initiatives that highlight the dramatic advances in both diagnosis and treatment of malignant brain tumors. Friday, October 30, 2015 (Preliminary Agenda/Subject to Change) 7:00AMRegistration, Continental Breakfast, and Exhibits 7:45AMWelcome & Introduction of Keynote Speakers David W. Andrews, MD, FACS Lyndon J. Kim, MD 8:00AM Keynote Lecture: Exploiting Viruses and Stem Cells for Glioma Therapy Frederick F. Lang, Jr, MD, FACS, FAANS Introduction: Kevin D. Judy, MD, FACS 8:40AM • A fternoon, profession-specific break-out sessions, providing additional opportunities for focused discussions and interactions. Each session will be designed to give practitioners updates in the latest trends and advances in neuro-oncology and learning will be reinforced through lively interactive case-based discussion. Lectures will also provide practitioners with updates in ongoing clinical trials at Jefferson as well as current outpatient brain tumor management. Educational Design At the conclusion of this conference, participants should be able to: Examine how viruses work and how they can be engineered for glioma therapy. Describe how molecular markers refine the diagnosis and management of diffuse glioma and evaluate their impact on both prognosis and treatment. Assess the plight of orphan diseases and the challenges of establishing evidence-based treatment data for small patient populations. Appraise the literature and the WHO Classification System for common brain tumors and cite sources where new knowledge has modified or changed the classification of certain tumors. Recognize how molecular markers refine the diagnosis and management of brain metastases Summarize the history of human experimentation from systemic cancers and evaluate their spanning from the mid-20th century to the impact on both prognosis and treatment. present and draw conclusions about evolution of FDA regulations for human research. Review and critique current treatment strategies for CNS lymphoma and evaluate the Evaluate current clinical trials at Jefferson as it metrics for establishing a cure for this disease. relates to patient centric care and validate the process for enrollment criteria for each trial. Examine how the current standard of care treatment negatively impacts the immune system Differentiate various radiation treatment methods and how this might influence an immunotherapy currently utilized for benign and malignant treatment for recurrent glioma treatment. disease and evaluate patient centric care needs, both during and after radiation therapy. Analyze the challenging anatomy of the sellar region and appreciate how recent innovations Analyze the detailed nature of outpatient care in treatment and outcomes have improved of brain tumor patients and identify the tools to patient care. determine the individual needs of patients and families, particularly during treatment. Appraise the methodology and technology of new fiberoptic laser technology and its Assess their individual practice in light of the application to challenging lesions such as information and discussions during the course, “butterfly” gliomas. and identify specific strategies to implement as part of a continuing improvement process for their practices. eynote Lecture: The Evolving Role of K Molecular Markers in the Diagnosis and Management of Diffuse Gliomas Jason T. Huse, MD, PhD Keynote Lecture: Targeted Therapeutics for Gliomas Tracy T. Batchelor, MD, MPH Introduction: Lyndon J. Kim, MD 9:20AM 10:00AMBreak & Exhibits 10:20AMUpdate for IND 14379-101: Immunotherapy Trial for Recurrent Glioma David W. Andrews, MD, FACS 10:50AMChemotherapy Redux: Resurrecting PCV Chemotherapy for Oligodendroglioma Jon Glass, MD 1:45PMApplication of Fiber-Optic Laser to Malignant Intracranial Disease Kevin D. Judy, MD, FACS 2:15PMReview of New Protocols for Craniopharyngioma and WHO Grade II Meningioma Christopher J. Farrell, MD 3:00PMUtilization of Molecular Genetic Profiling Test to Individualize Chemotherapy Treatment Lyndon J. Kim, MD 3:30PMAnticipating the 2016 WHO Fascicle on Brain Tumors: An Update Lawrence C. Kenyon, MD, PhD Nurse And Allied Health Professional Track: Updates From Jefferson Nurses ORCHESTRA BALLROOM 1:15PMWhen is a Novel Treatment Innovative and When is it Experimental? Catherine Harris, PhD, MBA, CRNP 1:45PMUpdate on Current Clinical Neuro-Oncology Trials at Jefferson Lauren Barbieri, CRNP 1:15PM Break/Move to Breakout Session 3:30PMInteractive Discussion: Case Presentations Two Afternoon Break-Out Sessions: Practicing and Question/Answer Physician Track and Nurses/Allied Health Moderator: Lauren Barbieri, CRNP Professionals Track. All attendees will re-convene Panelists: S akinah Abdulkhabir, RN, BSN after the afternoon break-out sessions for the Catherine Harris, PhD, MBA, CRNP Closing Remarks in the Symphony Ballroom. Gail Williams, DNP, CRNP, AOCNP SYMPHONY BALLROOM David W. Andrews, MD, FACS James J. Evans, MD, FACS Professor of Neurological Surgery Vice Chair, Clinical Services Department of Neurological Surgery Division Chief, Division of Neuro-Oncology Professor of Neurological Surgery and Otolaryngology – Head and Neck Surgery Director, Cranial Base and Pituitary Surgery Co-Director, Jefferson Center for Minimally Invasive Cranial Base and Endoscopic Neurosurgery Lauren Barbieri, CRNP Nurse Practitioner Department of Neurological Surgery FINAL PLENARY SESSION 4:00PMClosing Remarks David W. Andrews, MD, FACS 1:15PMUpdate in Minimally Invasive Cranial Base Surgery James J. Evans, MD, FACS For additional information please visit CME.Jefferson.edu Kevin D. Judy, MD, FACS Professor of Neurological Surgery Section Chief, Surgical Neuro-Oncology Guest Faculty 2:45PMBreak & Exhibits 2:15PMRadiation Therapy WBRT/SRS: Nursing Overview of the Radiation Treatment 11:20AMPanel of Invited Speakers: A Discussion of Methods for Brain Tumors Selected Cases from the Faculty Gail Williams, DNP, CRNP, AOCNP Moderator: David W. Andrews, MD, FACS Panelists: T racy T. Batchelor, MD, MPH 2:45PMBreak & Exhibits Jason T. Huse, MD, PhD Frederick F. Lang, Jr, MD, FACS, FAANS 3:00PMNursing Management of Patients with Brain Tumors in Ambulatory Care 12:30PM Lunch & Exhibits Sakinah Abdulkhabir, RN, BSN Practicing Physician Track: Updates From Jefferson Physicians Sidney Kimmel Medical College Course Directors Tracy T. Batchelor, MD, MPH Giovanni Armenise - Harvard Professor of Neurology, Harvard Medical School Executive Director, Stephen E. and Catherine Pappas Center for Neuro-Oncology, Massachusetts General Hospital Boston, Massachusetts Jason T. Huse, MD, PhD Assistant Member, Department of Pathology and Human Oncology and Pathogenis Program Memorial Sloan-Kettering Cancer Center New York, New York Frederick F. Lang, Jr, MD, FACS, FAANS Professor of Neurosurgery Director of Clinical Research, Department of Neurosurgery, Division of Surgery The University of Texas MD Anderson Cancer Center Houston, TX Sidney Kimmel Medical College Faculty Sakinah Abdulkhabir, RN, BSN Lawrence Kenyon, MD, PhD Nurse, Department of Neurological Surgery Associate Professor of Pathology, Anatomy, Cell Biology, and Neurology Christopher Farrell, MD Associate Professor of Neurological Surgery Lyndon Kim, MD Jon Glass, MD Associate Professor of Medical Oncology and Neurological Surgery Associate Professor of Neurology and Neurological Surgery Catherine Harris, PhD, MBA, CRNP Assistant Professor, Graduate Program Jefferson College of Nursing Gail Williams DNP, CRNP, AOCNP Nurse Practitioner, Department of Neurological Surgery For more information, please visit the course web page: CME.Jefferson.edu ACCREDITATION INFORMATION PHYSICIANS: Sidney Kimmel Medical College at Thomas Jefferson University is accredited by the ACCME to provide continuing medical education for physicians. Sidney Kimmel Medical College designates this live activity for a maximum of 6.75 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. NURSES: Thomas Jefferson University Hospital is an approved provider of continuing nursing education by the PA State Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. A maximum of 6.66 contact hours will be awarded to participants. PHYSICIAN ASSISTANTS: The American Academy of Physician Assistants accepts AMA PRA Category 1 Credit(s)™ (www.aapa.org). FACULTY DISCLOSURE All faculty participating in continuing medical education activities sponsored by Sidney Kimmel Medical College at Thomas Jefferson University are expected to disclose to the activity audience any real or apparent conflict(s) of interest related to the content of their presentation(s). Full disclosure of faculty relationships will be made at the activity. HOTEL ACCOMMODATIONS Please visit the course web page for hotel accommodation information. In keeping with Jefferson’s integrated approach to education and care, this Symposium is organized through the collaborative efforts of Jefferson’s Sidney Kimmel Cancer Center, and Sidney Kimmel Medical College at Thomas Jefferson University. 5th Annual Brain Tumor Symposium The New Revolution in Neuro-Oncology: Molecular Diagnoses and Targeted Treatments Friday, October 30, 2015 | DoubleTree by Hilton Hotel Philadelphia Center City 237 South Broad Street, Philadelphia, PA 19107 Course Description This CME Conference offers participants a unique opportunity to hear expert clinician leaders relate their knowledge of the field of neuro-oncology and current state-of-the-art advances. Cases will be examined from multiple perspectives, providing participants with clinical pearls for diagnosing and managing malignant brain tumors to improve patient outcomes. The course will feature: • M orning lectures devoted to the theme of the symposium: new research initiatives that highlight the dramatic advances in both diagnosis and treatment of malignant brain tumors. Friday, October 30, 2015 (Preliminary Agenda/Subject to Change) 7:00AMRegistration, Continental Breakfast, and Exhibits 7:45AMWelcome & Introduction of Keynote Speakers David W. Andrews, MD, FACS Lyndon J. Kim, MD 8:00AM Keynote Lecture: Exploiting Viruses and Stem Cells for Glioma Therapy Frederick F. Lang, Jr, MD, FACS, FAANS Introduction: Kevin D. Judy, MD, FACS 8:40AM • A fternoon, profession-specific break-out sessions, providing additional opportunities for focused discussions and interactions. Each session will be designed to give practitioners updates in the latest trends and advances in neuro-oncology and learning will be reinforced through lively interactive case-based discussion. Lectures will also provide practitioners with updates in ongoing clinical trials at Jefferson as well as current outpatient brain tumor management. Educational Design At the conclusion of this conference, participants should be able to: Examine how viruses work and how they can be engineered for glioma therapy. Describe how molecular markers refine the diagnosis and management of diffuse glioma and evaluate their impact on both prognosis and treatment. Assess the plight of orphan diseases and the challenges of establishing evidence-based treatment data for small patient populations. Appraise the literature and the WHO Classification System for common brain tumors and cite sources where new knowledge has modified or changed the classification of certain tumors. Recognize how molecular markers refine the diagnosis and management of brain metastases Summarize the history of human experimentation from systemic cancers and evaluate their spanning from the mid-20th century to the impact on both prognosis and treatment. present and draw conclusions about evolution of FDA regulations for human research. Review and critique current treatment strategies for CNS lymphoma and evaluate the Evaluate current clinical trials at Jefferson as it metrics for establishing a cure for this disease. relates to patient centric care and validate the process for enrollment criteria for each trial. Examine how the current standard of care treatment negatively impacts the immune system Differentiate various radiation treatment methods and how this might influence an immunotherapy currently utilized for benign and malignant treatment for recurrent glioma treatment. disease and evaluate patient centric care needs, both during and after radiation therapy. Analyze the challenging anatomy of the sellar region and appreciate how recent innovations Analyze the detailed nature of outpatient care in treatment and outcomes have improved of brain tumor patients and identify the tools to patient care. determine the individual needs of patients and families, particularly during treatment. Appraise the methodology and technology of new fiberoptic laser technology and its Assess their individual practice in light of the application to challenging lesions such as information and discussions during the course, “butterfly” gliomas. and identify specific strategies to implement as part of a continuing improvement process for their practices. eynote Lecture: The Evolving Role of K Molecular Markers in the Diagnosis and Management of Diffuse Gliomas Jason T. Huse, MD, PhD Keynote Lecture: Targeted Therapeutics for Gliomas Tracy T. Batchelor, MD, MPH Introduction: Lyndon J. Kim, MD 9:20AM 10:00AMBreak & Exhibits 10:20AMUpdate for IND 14379-101: Immunotherapy Trial for Recurrent Glioma David W. Andrews, MD, FACS 10:50AMChemotherapy Redux: Resurrecting PCV Chemotherapy for Oligodendroglioma Jon Glass, MD 1:45PMApplication of Fiber-Optic Laser to Malignant Intracranial Disease Kevin D. Judy, MD, FACS 2:15PMReview of New Protocols for Craniopharyngioma and WHO Grade II Meningioma Christopher J. Farrell, MD 3:00PMUtilization of Molecular Genetic Profiling Test to Individualize Chemotherapy Treatment Lyndon J. Kim, MD 3:30PMAnticipating the 2016 WHO Fascicle on Brain Tumors: An Update Lawrence C. Kenyon, MD, PhD Nurse And Allied Health Professional Track: Updates From Jefferson Nurses ORCHESTRA BALLROOM 1:15PMWhen is a Novel Treatment Innovative and When is it Experimental? Catherine Harris, PhD, MBA, CRNP 1:45PMUpdate on Current Clinical Neuro-Oncology Trials at Jefferson Lauren Barbieri, CRNP 1:15PM Break/Move to Breakout Session 3:30PMInteractive Discussion: Case Presentations Two Afternoon Break-Out Sessions: Practicing and Question/Answer Physician Track and Nurses/Allied Health Moderator: Lauren Barbieri, CRNP Professionals Track. All attendees will re-convene Panelists: S akinah Abdulkhabir, RN, BSN after the afternoon break-out sessions for the Catherine Harris, PhD, MBA, CRNP Closing Remarks in the Symphony Ballroom. Gail Williams, DNP, CRNP, AOCNP SYMPHONY BALLROOM David W. Andrews, MD, FACS James J. Evans, MD, FACS Professor of Neurological Surgery Vice Chair, Clinical Services Department of Neurological Surgery Division Chief, Division of Neuro-Oncology Professor of Neurological Surgery and Otolaryngology – Head and Neck Surgery Director, Cranial Base and Pituitary Surgery Co-Director, Jefferson Center for Minimally Invasive Cranial Base and Endoscopic Neurosurgery Lauren Barbieri, CRNP Nurse Practitioner Department of Neurological Surgery FINAL PLENARY SESSION 4:00PMClosing Remarks David W. Andrews, MD, FACS 1:15PMUpdate in Minimally Invasive Cranial Base Surgery James J. Evans, MD, FACS For additional information please visit CME.Jefferson.edu Kevin D. Judy, MD, FACS Professor of Neurological Surgery Section Chief, Surgical Neuro-Oncology Guest Faculty 2:45PMBreak & Exhibits 2:15PMRadiation Therapy WBRT/SRS: Nursing Overview of the Radiation Treatment 11:20AMPanel of Invited Speakers: A Discussion of Methods for Brain Tumors Selected Cases from the Faculty Gail Williams, DNP, CRNP, AOCNP Moderator: David W. Andrews, MD, FACS Panelists: T racy T. Batchelor, MD, MPH 2:45PMBreak & Exhibits Jason T. Huse, MD, PhD Frederick F. Lang, Jr, MD, FACS, FAANS 3:00PMNursing Management of Patients with Brain Tumors in Ambulatory Care 12:30PM Lunch & Exhibits Sakinah Abdulkhabir, RN, BSN Practicing Physician Track: Updates From Jefferson Physicians Sidney Kimmel Medical College Course Directors Tracy T. Batchelor, MD, MPH Giovanni Armenise - Harvard Professor of Neurology, Harvard Medical School Executive Director, Stephen E. and Catherine Pappas Center for Neuro-Oncology, Massachusetts General Hospital Boston, Massachusetts Jason T. Huse, MD, PhD Assistant Member, Department of Pathology and Human Oncology and Pathogenis Program Memorial Sloan-Kettering Cancer Center New York, New York Frederick F. Lang, Jr, MD, FACS, FAANS Professor of Neurosurgery Director of Clinical Research, Department of Neurosurgery, Division of Surgery The University of Texas MD Anderson Cancer Center Houston, TX Sidney Kimmel Medical College Faculty Sakinah Abdulkhabir, RN, BSN Lawrence Kenyon, MD, PhD Nurse, Department of Neurological Surgery Associate Professor of Pathology, Anatomy, Cell Biology, and Neurology Christopher Farrell, MD Associate Professor of Neurological Surgery Lyndon Kim, MD Jon Glass, MD Associate Professor of Medical Oncology and Neurological Surgery Associate Professor of Neurology and Neurological Surgery Catherine Harris, PhD, MBA, CRNP Assistant Professor, Graduate Program Jefferson College of Nursing Gail Williams DNP, CRNP, AOCNP Nurse Practitioner, Department of Neurological Surgery For more information, please visit the course web page: CME.Jefferson.edu ACCREDITATION INFORMATION PHYSICIANS: Sidney Kimmel Medical College at Thomas Jefferson University is accredited by the ACCME to provide continuing medical education for physicians. Sidney Kimmel Medical College designates this live activity for a maximum of 6.75 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. NURSES: Thomas Jefferson University Hospital is an approved provider of continuing nursing education by the PA State Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. A maximum of 6.66 contact hours will be awarded to participants. PHYSICIAN ASSISTANTS: The American Academy of Physician Assistants accepts AMA PRA Category 1 Credit(s)™ (www.aapa.org). FACULTY DISCLOSURE All faculty participating in continuing medical education activities sponsored by Sidney Kimmel Medical College at Thomas Jefferson University are expected to disclose to the activity audience any real or apparent conflict(s) of interest related to the content of their presentation(s). Full disclosure of faculty relationships will be made at the activity. HOTEL ACCOMMODATIONS Please visit the course web page for hotel accommodation information. In keeping with Jefferson’s integrated approach to education and care, this Symposium is organized through the collaborative efforts of Jefferson’s Sidney Kimmel Cancer Center, and Sidney Kimmel Medical College at Thomas Jefferson University. 5th Annual Brain Tumor Symposium PAID PERMIT NO. #117 SOUTHEASTERN, PA 19399 The New Revolution in Neuro-Oncology: Molecular Diagnoses and Targeted Treatments NON-PROFIT ORG U.S. POSTAGE 5th Annual Brain Tumor Symposium Friday, October 30, 2015 | DoubleTree by Hilton Hotel Philadelphia Center City 237 South Broad Street, Philadelphia, PA 19107 The New Revolution in Neuro-Oncology: Molecular Diagnoses and Targeted Treatments Registration Fees Practicing Physician $165 Nurse / Nurse Practitioner $140 Allied Health Professional $140 Jefferson Affiliate Hospitals - Practicing Physician $125 Jefferson Affiliate Hospitals - Nurse / Allied Health Professional $105 Non-Jefferson Resident $100 Non-Jefferson Fellow $100 ATION REGISTR N OW ! OPEN The registration fee includes all course materials, access to presentations online, CE certificate, breakfast, refreshment breaks and lunch. The registration fee does not include parking. HOME CME ACTIVITIES | Sidney Kimmel Medical College RSS/GRAND ROUNDS LEARNING GROUPS CREDIT HISTORY CONTACT US *Registration Deadline is: October 28, 2015* Registrations should be submitted online by this date. Registrations cannot be processed without payment. Should you need additional assistance or if you have any special needs, please contact the Office of CME at 215-955-6992 or via email at jeffersoncme@Jefferson.edu. Paper registration available upon request. Department of Neurological Surgery As an integral part of Jefferson Hospital for Neuroscience, the region’s only dedicated hospital for neuroscience, the Department of Neurological Surgery is one of the busiest academic neurosurgical programs in the country, offering state-of-the-art treatment to patients with neurological diseases affecting the brain and spine, such as brain tumors, spinal disease, vascular brain diseases, epilepsy, pain, Parkinson’s disease and many other neurological disorders. Jefferson.edu/university/jmc/departments/neurosurgery.html Registration Now Open! Thomas Jefferson University Register Office of Continuing Medical Education 1020 Locust Street, Suite M-5 Philadelphia, PA 19107 Log in Have a smart phone? Go to scanlife.com to download your free QR code reader Step #2 – Once you are logged in, you may register for this conference by clicking the “CME Activities” tab located on the top of the page, and clicking on the activity name “5th Annual Brain Tumor Symposium”. • Review the course webpage, and scroll down to see the registration options. • Complete the online registration process. • You will receive a confirmation email of your successful registration. • If you are unable to attend, cancellation fees may be applied. Please refer to the Cancellation/Refund Policy located on the course webpage at CME.Jefferson.edu. Friday, October 30, 2015 Step #1 – Login to your account on CPD@JeffLearn™ at CME.Jefferson.edu. • If you do not have an account, step by step instructions can be found on the CPD@JeffLearn™ webpage. • Click “Login” if you have an account. Click “Register” to create an account The New Revolution in Neuro-Oncology: Molecular Diagnoses and Targeted Treatments Important Browser Information – site works best on Google CHROME, Mozilla FIREFOX, SAFARI or OPERA. Please be sure you are running the most recent version of your browser. 5th Annual Brain Tumor Symposium Here’s How to Register Online Today at CME.Jefferson.edu: Friday, October 30, 2015 DoubleTree by Hilton Hotel Philadelphia Center City Featured Guest Speakers Tracy T. Batchelor, MD, MPH Jason T. Huse, MD, PhD Frederick F. Lang, Jr, MD, FACS, FAANS