FK
Technology
of
Wet Grinding
Pharma and Cosmetics
25.- 28.October 2003
Hans Brogli
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Contents
 Definition Grinding, Wet Grinding
 Characterisation
 Modula Grinding Aggregates
 Annular Gap Mill CoBall-Mill
 Applications
 Summary
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Grinding
We differentiate between:
Wet Grinding
Dry Grinding
 Grinding
 Dispersing
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Wet Grinding
Grinding
 Crushing of solid matters, crystals or fibres in
small parts in a fluid, e.g. active substances,
colour pigments
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Wet Grinding
Dispersing
 destroying of agglomerates, wetting and
homogeneous dispersing in a fluid, e.g.
toothpaste, lipstick
Emulsifying
 merging of two not mixable fluids (oil,
water) under the effect of shear forces,
turbulences and an emulsifier e.g.
ointments, body cream
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Pharma/Cosmetics
Characterisation
 Effect of mechanical forces
Different products are milled on our mills by
impact, pressure, shear forces, cutting or friction
 Resistability
- hard-elastic, fibrous fruit flesh, coconut flesh,
aloe vera plants
- hardness of crystalline parts up to mohs hardness 9.5
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FK
Wet Grinding
Continuous Mills
 Perforated Disc Mills
 Toothed Colloid Mill
 Corundum Stone Mill
 In-Line Homogenizer
 Annular Gap Mill
CoBall-Mill
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Modula
“Modula“
The new dimension
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Grinding Aggregates
Mills M/ML, M/MZ, M/MK
Open Execution, Outlet open
 Feeding with hopper
 Feeding with hopper and feeding screw
 Feeding with pump
In-line Execution
Closed Execution, Outlet pipeline
 Inlet connected to a tank
 Feeding with pump
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Perforated Disc Mill
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Perforated Disc Mill M/ML
Crushing, Pre-grinding
 Size up to 100 mm
 Fineness approx 1 mm
The desired fineness is adjusted by the
size of the holes in the perforated discs
Hole dia. 1.5 to 20 mm or slotted discs
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Toothed Colloid Mill M/MZ
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Toothed Colloid Mill M/MZ
Fine Grinding
 Starting size depending on
product up to 5mm
 Fineness approx 100 µ
The desired fineness
is adjustable with
 Toothing, coarse, normal, crosswise
 Grinding gap infinitely adjustable
(gap between rotor and stator)
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Corundum Stone Mill M/MK
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Corundum Stone Mill
Finest Grinding
 Fineness 30 - 50 µ
The desired fineness is adjustable
with
 Different graining of grinding discs
grain 20 to 120
 Grinding gap infinitely adjustable
(gap between rotor- and stator disc)
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Modula
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Modula
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Modula - Range
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Type
Toothed Colloid
Mill
Tool
Diameter
[mm]
Drive
Capacity
[kW]
Throughput
[kg/h]
M/MZ-80
80
5.5
100 - 1000
M/MZ-130
130
15
500 - 5000
M/MZ-150
150
22
1000 - 10000
M/MZ-190
190
45
2000 - 20000
M/MZ-250
250
75
3000 - 40000
Type
Corundum Stone
Mill
Tool
Diameter
[mm]
Drive
Capacity
[kW]
Throughput
[kg/h]
M/MK-95
95
5.5
20 - 200
M/MK-160
160
11
60 - 800
M/MK-180
180
11
150 - 1500
M/MK-250
250
22
300 - 3000
M/MK-300
300
45
400 - 4000
Type
Perforated Disc
Mill
Tool
Diameter
[mm]
Drive
Capacity
[kW]
Throughput
[kg/h]
M/ML-150
150
Pharma/Cosmetics
5.5
200 - 2000
FK
Modula M/DIL
 Dispersing, crushing of
agglomerates
 Emulsifying
 Exchangeable rotor-, stator
elements, different toothing
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Modula M/DIL
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M/DIL - Range
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Type
DisHo-Inline
Tool Diameter
[mm]
Drive Capacity
[kW]
Throughput
based on: Water [l/h]
M/DIL-100
100
7,5
7000
M/DIL-160
160
22
40000
M/DIL-180
180
45
60000
M/DIL-230
200
110
85000
Pharma/Cosmetics
Annular Gap CoBall Mill
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FK
Processing CoBall Mill
product outlet
cooling
medium
outlet
cooling
medium
product inlet
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beads
outlet
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CoBall Mill
Finest grinding down to the Nano range < 0.5 µ
Adjusting Possibilities
 Rotor speed
 Diameter of grinding beads and grinding gap
(rotor).
 Material of grinding beads (spec. weight)
 Degree of beads filling
 Capacity
 Product temperature
 Product viscosity (contents of dry substances)
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CoBall Mill
MS-12
MS-50
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CoBall Mill
Advantages
 Narrow grinding gap (four
times beads diameter) high
energy density  narrow
grain spectrum
 Optimum cooling, all
surfaces rotor, stator, lid
coolable
 Smooth grinding elements resistant to wear, no pins, naps
etc.
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CoBall Mill
 Products from fluid to very viscous can be processed
 Cleaning, sterilizing and drying without emptying of
grinding beads
 Small grinding chamber volume
- Little remnants at product change
- Quick cleaning, little consumption of cleaning material
- Easy and efficient change of products
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CoBall Mill - Range
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Typ
MS-12
MS-18
MS-32
MS-50
Rotor
diameter
(mm)
120
180
320
500
Rotor
Driving
capacity (kw)
2,2- 3
5,5- 11
18,5- 30
37- 55
Throughput
(l/h)
10- 40
30- 80
60- 300
200- 1000
Net weight
(kg) (approx.)
160
400
800
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Applications
Pharma
suspensions, ointments,
veterinary products, eye
drops, tablet coating, activesubstances, clotrimazole,
betametasone, etc.
Cosmetics
creams, emulsions, lipstick,
nail polish, mascara, eye
shadow, titandioxyde, animal
skins, shrimp shells, plants,
roots, aloe vera etc.
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Summary
 All mill types are constructed according to GMP
guidelines
 All mills can be equipped with CIP, SIP and DIP
 Delivery with all qualification documents, possibility
of validation
 All lubricants with USDA-H1 admission
 For clean rooms all mills can be delivered with water
cooled motors (no turbulences)
 Products with a viscosity from fluid to highly viscous
can be processed
 Due to the new modular construction all mills are easy
to handle and quickly convertable
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