Source: Edition: Country: Date: Page: Area: Circulation: Ad data: Phone: The Daily Telegraph {Main} Keyword: University College London UK Friday 17, October 2014 12 105 sq. cm ABC 505473 Daily page rate £46,000.00, scc rate £214.00 020 7931 2000 -D>FPK<I DINOMPH@IO <I?C@GKTJPM =M<DIOJBMJR By Sarah Knapton, Science Editor MASTERING a musical instrument, or another new skill, makes the brain grow, scientists have found. A fatty substance which is a major component of the brain’s white matter is laid down with each physical skill people learn, researchers at University College London found. The substance, myelin, is constantly produced by the brain and spinal cord into early adulthood as it is needed for many developmental processes. When a child learns to walk or an adult masters a skill such as juggling, new neural circuit activity is needed and highspeed connections are made across large distances between parts of the brain and spinal cord. Tests in lab mice showed that new myelin must also be made each time a skill is learned later in life. Mice which had been genetically engineered so they could not produce myelin failed to learn how to run on a complex wheel. Normal mice were able to pick up the new skill. “From earlier studies of human white matter we thought myelin might be involved in some way in skill learning, so we decided to attack this idea experimentally,” said Prof Bill Richardson, director of the Wolfson Institute for Biomedical Research at UCL. “We were surprised how quickly we saw differences in the ability of mice from each group to learn how to run on a complex wheel, which shows just how fast the brain can respond to wrap newlyactivated circuits in myelin and how this improves learning.” The study, published in the journal Science, is the first to experimentally confirm the role of white matter in learning. Prof Richardson said it could solve “some of the mysteries still surrounding how the brain adapts and learns throughout life”. Reproduced by Gorkana under licence from the NLA (newspapers), CLA (magazines), FT (Financial Times/ft.com) or other copyright owner. No further copying (including printing of digital cuttings), digital reproduction/forwarding of the cutting is permitted except under licence from the copyright owner. All FT content is copyright The Financial Times Ltd. Article Page 1 of 1 299815756 - SIMWAL - A20373-1 - 91480494