Research overview and ETF
Dave Berry, Research Manager
NeSC Review, May 27th
Engineering Task Force
Our 0.5 FTE is Anthony Stell
AAA action line
How-to guides on setting up PERMIS and
GT3.3 to support Grid based authorisation
GT4 evaluation
Our focus is PERMIS integration
Condor pool for OMII testing
OMII evaluation
Managed by Dave Berry
Scottish Bioinformatics
Research Network
Funded (£2.4M) by Scottish Enterprise, SHEFC,
Scottish Executive Environment and Rural
Affairs Department
Involves Glasgow, Dundee, Edinburgh, Scottish
Bioinformatics Forum
Aim to provide bioinformatics infrastructure
for Scottish health, agriculture and industry
Infrastructure support at Dundee, Edinburgh and Glasgow
to support first-rate research in bioinformatics at each
academic institute
Infrastructure support at three institutes, to support interinstitutional sharing of compute and data resources
through application of Grid computing
Outreach and training activities mediated by the Scottish
Bioinformatics Forum
Generation Scotland Scottish
Family Health Study
Funded by Health Department and Department
for Enterprise and Lifelong Learning
Involves Glasgow, Dundee, Edinburgh, Aberdeen
Genetics as applied to healthcare
Emphasis of first two years on providing a platform for
research into the genetic basis of common complex diseases
in Scotland
X
X
Mental health, cardiovascular, …
Plan to establish 15,000 family-based intensively-phenotyped cohort
recruited from the East and West of Scotland
Basis for neutralising heritable (genetic) risk factors in disease
surveillance, treatment optimisation, avoidance of adverse
drug events and prediction of response to therapy, health care
planning and drug discovery, …
GridQTL: High performance QTL
analysis via the Grid
Execute QTL analyses on grid computing resources
Describe parallel computation requirements
Automatic task-level decomposition of analysis requests
Schedule, monitor and re-start decomposed tasks
Provide a secure and private data space for each researcher
Synchronise application input and output
Enable analysis re-start from intermediate results
Be a robust public service
GridQTL Portal
Analysis 1
Data
Mgr
Analysis 2
Analysis
Portlet
Analysis 3
Analysis 4
Analysis 5
Meta
Sched
UK e-Science Grid
or NGS Resources
VOTES
Virtual Organisations for Trials and Epidemiological
Studies
3 year MRC (£2.9M) funded project Plans to develop Grid
infrastructure to address key components of clinical
trial/observational study
X
X
X
Recruitment of potentially eligible participants
Data collection during the study
Study administration and coordination
– Involves Glasgow, Oxford, Leicester, Nottingham, Manchester
Clinical Virtual Organisation Framework
Used to realise
CVO-1
(e.g. for data
collection)
CVO-2
(e.g. for
recruitment)
LeiNott
GLA
Transfer
Grid
GPs
OX
IMP
Clinical trial
data sets
Disease
registries
Hospital
databases
DyVOSE
Dynamic Virtual Organisations for e-Science Education
(DyVOSE) project
Exploring advanced authorisation infrastructures for
security
X
X
In Grid Computing Module as part of advanced MSc at Glasgow
Provide insight into rolling Grid out to the masses!
ScotGrid
GU Condor pool
Other (known!)
Grid resources
Education
VO policies
PERMIS based
Authorisation checks
Authorisation decisions
NextGrid
Slide from Malcolm
ESLEA
Slide from Pete
ReQueST: Resource Quantification
in e-Science Technologies
EPSRC Fundamental CS for e-Science
Applies existing CS research – “proof-carrying
code” – to e-Science
X
Uses this to test the CS with real applications
Produces new CS research for the future
2 RA’s for 3 years
Specifies the resources required by a
Grid request
Proof can be checked by the server
X
no need to trust user
Accurate resource quantification from code
analysis
Inferring Quality of Service
Properties
EPSRC-funded studentship
Using bell curves as measures of QoS
Run time, accuracy, reliability…
Investigating combining operators
Sum, product, max, min, conditional
Find approximations to results
Extend to other curve types
E.g. log-normal for runtime
Incorporate into a calculus
Inter-Enterprise Computing
Network (IECnet)
DTI Knowledge Transfer Network
3 years from 1st February 2005
Exploiting the use of Grid computing
technologies in UK industry
Lead partner: Intellect UK
Project manager: Ian Osborne
E-Science partner: NeSC
Technical lead: Dave Berry
Advisory council
Vendors, adopters and e-Scientists