Dave Berry, Research Manager
NeSC Review, May 27th

Our 0.5 FTE is Anthony Stell
AAA action line
How-to guides on setting up PERMIS and
GT3.3 to support Grid based authorisation
GT4 evaluation
Our focus is PERMIS integration
Condor pool for OMII testing
OMII evaluation
Managed by Dave Berry

Scottish Bioinformatics
Research Network
Funded (£2.4M) by Scottish Enterprise, SHEFC,
Scottish Executive Environment and Rural
Affairs Department
Involves Glasgow, Dundee, Edinburgh, Scottish
Bioinformatics Forum
Aim to provide bioinformatics infrastructure for Scottish health, agriculture and industry
Infrastructure support at Dundee, Edinburgh and Glasgow to support first-rate research in bioinformatics at each academic institute
Infrastructure support at three institutes, to support interinstitutional sharing of compute and data resources through application of Grid computing
Outreach and training activities mediated by the Scottish
Bioinformatics Forum

Generation Scotland Scottish
Family Health Study
Funded by Health Department and Department for Enterprise and Lifelong Learning
Involves Glasgow, Dundee, Edinburgh, Aberdeen
Genetics as applied to healthcare
Emphasis of first two years on providing a platform for research into the genetic basis of common complex diseases in Scotland


Mental health, cardiovascular, …
Plan to establish 15,000 family-based intensively-phenotyped cohort recruited from the East and West of Scotland
Basis for neutralising heritable (genetic) risk factors in disease surveillance, treatment optimisation, avoidance of adverse drug events and prediction of response to therapy, health care planning and drug discovery, …

GridQTL: High performance QTL analysis via the Grid
Execute QTL analyses on grid computing resources
Describe parallel computation requirements
Automatic task-level decomposition of analysis requests
Schedule, monitor and re-start decomposed tasks
Provide a secure and private data space for each researcher
Synchronise application input and output
Enable analysis re-start from intermediate results
Be a robust public service
GridQTL Portal
Data
Mgr
Analysis
Portlet
Analysis 1
Analysis 2
Analysis 3
Analysis 4
Analysis 5
Meta
Sched UK e-Science Grid or NGS Resources

Virtual Organisations for Trials and Epidemiological
Studies
3 year MRC (£2.9M) funded project Plans to develop Grid infrastructure to address key components of clinical trial/observational study


Recruitment of potentially eligible participants
Data collection during the study

Study administration and coordination
– Involves Glasgow, Oxford, Leicester, Nottingham, Manchester
Clinical Virtual Organisation Framework
Used to realise
CVO-2
(e.g. for recruitment)
CVO-1
(e.g. for data collection)
Disease registries
GPs
GLA
Transfer
Grid
Lei-
Nott
OX
IMP
Hospital databases
Clinical trial data sets

Dynamic Virtual Organisations for e-Science Education
(DyVOSE) project
Exploring advanced authorisation infrastructures for security
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
In Grid Computing Module as part of advanced MSc at Glasgow
Provide insight into rolling Grid out to the masses!
ScotGrid GU Condor pool
Other (known!)
Grid resources
Education
VO policies
PERMIS based tio
Authorisation decisions n

Slide from Malcolm

Slide from Pete

ReQueST: Resource Quantification in e-Science Technologies
EPSRC Fundamental CS for e-Science
Applies existing CS research – “proof-carrying code” – to e-Science

Uses this to test the CS with real applications
Produces new CS research for the future
2 RA’s for 3 years
Specifies the resources required by a
Grid request
Proof can be checked by the server
 no need to trust user
Accurate resource quantification from code analysis

EPSRC-funded studentship
Using bell curves as measures of QoS
Run time, accuracy, reliability…
Investigating combining operators
Sum, product, max, min, conditional
Find approximations to results
Extend to other curve types
E.g. log-normal for runtime
Incorporate into a calculus

DTI Knowledge Transfer Network
3 years from 1 st February 2005
Exploiting the use of Grid computing technologies in UK industry
Lead partner: Intellect UK
Project manager: Ian Osborne
E-Science partner: NeSC
Technical lead: Dave Berry
Advisory council
Vendors, adopters and e-Scientists