UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
AMMONIUM CHLORIDE
Table of Contents
Ref. No.
MSDS /PD/47_01
Valid for:
2 years from approval
Page
1. Chemical Product
2. Composition and Information on Ingredients
3. Hazards Identification
4. First Aid Measures
5. Fire and Explosion Data
6. Accidental Release Measures
7. Handling and Storage
8. Exposure Controls/ Personal Protection
9. Physical and Chemical Properties
10. Stability and Reactivity Data
11. Toxicological Information
12. Ecological Information
13. Disposal Considerations
14. References
15. Appendices
16. Revision History
Page 1 of 7
2
2
2
2
3
4
4
4
4
5
5
6
6
6
7
7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
AMMONIUM CHLORIDE
Ref. No.
MSDS /PD/47_01
Valid for:
2 years from approval
1.
Chemical Product
Product Name: Ammonium Chloride
Chemical name: Ammonium Chloride
Synonyms: Ammonium Chloratum; Ammonium Chloridum; Ammonium Muriate; Sal
Ammonia; Salmiac
Chemical Formula: NH4Cl
2.
Composition and Information on Ingredients
Composition: Ammonium Chloride
Toxicological Data on Ingredients:
ORAL (LD50):
Acute: 1650 mg/kg [Rat.]
1300 mg/kg [Mouse]
3.
Hazards Identification
Potential Acute Health Effects: May cause eye and skin irritation, and is slightly hazardous
in case of ingestion and inhalation.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not Applicable
MUTAGENIC EFFECTS: Not Applicable
TERATOGENIC EFFECTS: Not Applicable
DEVELOPMENTAL TOXICITY: Not Applicable
4.
First Aid Measures
General measures:
Skin contact: Immediately flush skin with plenty of water and afterwards cover irritated skin
with an emollient. Seek medical attention.
Page 2 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
AMMONIUM CHLORIDE
Ref. No.
MSDS /PD/47_01
Valid for:
2 years from approval
Serious skin contact: Wash contaminated area with disinfectant soap and cover with an antibacterial cream. Seek immediate medical attention.
Eye contact: Remove any contact lenses and immediately flush eyes with plenty of water for
at least 15 minutes. Seek medical attention.
Ingestion: Loosen tight clothing such as a collar, tie, belt or waistband. Do not induce
vomiting unless directed by medical personnel. Seek medical attention.
Serious ingestion: Not Applicable
Inhalation: Move victim to fresh air. If not breathing, give artificial respiration and if
breathing is difficult, give oxygen. Seek medical attention.
Serious inhalation: Not Applicable
5.
Fire and Explosion Data
Flammability of the Product: Non-flammable
Auto-Ignition Temperature: Not Applicable
Flash points: Not Applicable
Flammable limits: Not Applicable
Products of Combustion: Not Applicable
Fire Hazards in Presence of Various Substances: Not Applicable
Explosion Hazards in Presence of Various Substances: Not Applicable
Fire fighting media and Instructions: Not Applicable
Special Remarks on Fire Hazards: Reaction between Ammonium Chloride and Bromine
pentafluoride at ambient or slightly elevated temperature is violent, and ignition often occurs.
Page 3 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
AMMONIUM CHLORIDE
Ref. No.
MSDS /PD/47_01
Valid for:
2 years from approval
Special Remarks on Explosion Hazards: Explosive reaction between bromine trifluoride
and ammonium halides.
6.
Accidental Release Measures
NB: Wear appropriate protective equipment/clothing including gloves before removing
any spills.
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal
container and afterwards clean the contaminated area with water.
Large Spill: Use a shovel to put the material into a convenient waste disposal container.
7.
Handling and Storage
Precautions: Avoid contact with skin and eyes and do not breathe dust. Keep away from
incompatibles such as oxidising agents, acids, alkalis.
Storage: Keep in a tightly closed container which is stored in a cool, well-ventilated area.
8.
Exposure Controls/Personal Protection
Airborne Exposure Limits:
Inhalation TWA: 10 STEL: 20 (mg/m3) [United Kingdom (UK)]
Engineering Controls: Use process enclosures, local exhaust ventilation to keep airborne
levels low.
Personal Protection: Wear splash goggles, lab coat appropriate dust respirator and gloves.
9.
Physical and Chemical Properties
Physical state and appearance: White solid crystalline powder
Odour: Odourless
Taste: Cooling, Saline
Molecular Weight: 53.49g
pH (5% solution/water): 5.5
Boiling Point: 520°C (968°F)
Melting Point: Decomposition temperature: 338°C (640.4°F)
Critical Temperature: Not Applicable
Page 4 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
AMMONIUM CHLORIDE
Ref. No.
MSDS /PD/47_01
Valid for:
2 years from approval
Specific Gravity (Water = 1): 1.53 (Water = 1)
Vapour Pressure (mmHg): Not Applicable
Vapour Density: Not Applicable
Volatility: Not Applicable
Odour Threshold: Not Applicable
Water/Oil Distribution Coefficient: Not Applicable
Ionicity (in Water): Not Applicable
Dispersion Properties: Not Applicable
Solubility: Soluble in cold water, hot water and methanol; insoluble in diethyl ether and
acetone. Almost insoluble in ethyl acetate.
10.
Stability and Reactivity Data
Stability: Stable
Corrosivity: In presence of steel and of stainless steel; extremely corrosive in presence of
copper; slightly corrosive in presence of aluminum. Severe corrosive effect on brass and
bronze.
Instability temperature: Not Applicable
Conditions of Instability: Moisture
Incompatibles: Reactive with oxidising agents, acids andalkalis
Polymerization: Not Applicable
11.
Toxicological Information
Toxicity to animals:
Acute oral toxicity (LD50): 1300 mg/kg [Mouse]
Effects on humans:
Acute potential health effects: Slightly hazardous in case of skin contact (irritant,
sensitiser), ingestion and inhalation.
Chronic potential health effects:
MUTAGENIC EFFECTS: Not Applicable
Page 5 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
AMMONIUM CHLORIDE
Ref. No.
MSDS /PD/47_01
Valid for:
2 years from approval
TERATOGENIC EFFECTS: Not Applicable
DEVELOPMENTAL TOXICITY: Not Applicable
Other information: Not Applicable
12.
Ecological Information
Ecotoxicity: Toxic to aquatic life.
EC50 American lobster (Homarus americanus): 0.237 mg/l 48.00 hours
13.
Disposal Considerations
Waste Disposal: What is not recycled must be handled as hazardous waste and sent to an
approved incinerator or disposed in an approved waste facility. Dispose of container and
unused contents in accordance with local environmental control regulations.
Discard in a container marked as HALOGENATED WASTE.
14.
References
- ScienceLab.com Material Safety Data Sheet; Ammonium Chloride. [online]. 2013
[cited
2014
Jan
23].
Available
from:
URL:
http://www.sciencelab.com/msds.php?msdsId=9927431
- Avantor. Material Safety Data Sheet. [online]. 2011 [cited 2014 Jan 23]. Available
from:
URL:
http://www.avantormaterials.com/documents/MSDS/usa/English/A5724_msds_us_co
v_Default.pdf
- Material Safety Data Sheet; Ammonium Chloride. [online]. 2000 [cited 2014 Jan 23].
Available from: URL: http://avogadro.chem.iastate.edu/msds/nh4cl.htm
Page 6 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
AMMONIUM CHLORIDE
Ref. No.
MSDS /PD/47_01
Valid for:
2 years from approval
15.
Appendices
Not applicable
16.
Revision History
Version Number
Amendments/ Reasons for change
01
Initial Release
Page 7 of 7