UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM BICARBONATE
Table of Contents
Valid for:
2 years from approval
Page
1. Chemical Product
2. Composition and Information on Ingredients
3. Hazards Identification
4. First Aid Measures
5. Fire and Explosion Data
6. Accidental Release Measures
7. Handling and Storage
8. Exposure Controls/ Personal Protection
9. Physical and Chemical Properties
10. Stability and Reactivity Data
11. Toxicological Information
12. Ecological Information
13. Disposal Considerations
14. Other Information
15. References
16. Appendices
17. Revision History
Page 1 of 10 Ref. No.
MSDS /PD/10_01
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UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM BICARBONATE
Ref. No.
MSDS /PD/10_01
Valid for:
2 years from approval
Chemical Product
1.
Product Name: Sodium bicarbonate
Chemical name: Sodium bicarbonate
Synonyms: Baking soda, bicarbonate of soda, sodium acid carbonate, monosodium
carbonate, sodium hydrogen carbonate, carbonic acid monosodium salt
Chemical Formula: NaHCO3
2.
Composition and Information on Ingredients
Composition: Sodium bicarbonate 100% by weight
Toxicological Data on Ingredients: Not applicable.
3.
Hazards Identification
Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye
contact (irritant), ingestion and inhalation.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: N/A
MUTAGENIC EFFECTS: N/A
TERATOGENIC EFFECTS: N/A
DEVELOPMENTAL TOXICITY: N/A. Repeated or prolonged exposure is not known to aggravate
medical condition.
Page 2 of 10 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
4.
SODIUM BICARBONATE
Ref. No.
MSDS /PD/10_01
Valid for:
2 years from approval
First Aid Measures
General measures: N/A
Skin contact: Wash with soap and water and cover the irritated skin with an emollient. Seek
medical attention if irritation develops. Cold water may be used.
Serious skin contact: N/A
Eye contact: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the
upper and lower eyelids. Seek medical aid and DO NOT allow victim to rub or keep eyes
closed.
Ingestion: DO NOT induce vomiting unless directed to do so by medical personnel, and never
give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie,
belt or waistband. Seek medical attention if symptoms appear.
Serious indigestion: N/A
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Seek medical attention.
Serious inhalation: N/A
Page 3 of 10 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
5.
SODIUM BICARBONATE
Ref. No.
MSDS /PD/10_01
Valid for:
2 years from approval
Fire and Explosion Data
Flammability of the Product: Non flammable.
Auto-Ignition Temperature: Not applicable.
Flash points: Not applicable.
Flammable limits: Not applicable.
Products of Combustion: N/A
Fire Hazards in Presence of Various Substances: Not applicable. Explosion Hazards in Presence of Various Substances:
- Risks of explosion of the product in presence of mechanical impact: N/A
- Risks of explosion of the product in presence of static discharge: N/A
Fire fighting media and Instructions: Not applicable.
Special Remarks on Fire Hazards: When heated to decomposition it emits acrid smoke and
irritating fumes.
Special Remarks on Explosion Hazards: Not applicable.
Page 4 of 10 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
6.
SODIUM BICARBONATE
Ref. No.
MSDS /PD/10_01
Valid for:
2 years from approval
Accidental Release Measures
NB: Wear appropriate protective equipment/clothing including gloves before removing
any spills.
Small spill: Use appropriate tools to put the spilled solid in a convenient waste disposal
container. Finish cleaning by spreading water on the contaminated surface and dispose of
according to local and regional authority requirements.
Large spill: Use a shovel to put the material into a convenient waste disposal container. Finish
cleaning by spreading water on the contaminated surface and allow to evacuate through the
sanitary system.
7.
Handling and Storage
Precautions: Do not ingest. Do not breathe dust. If ingested, seek medical advice immediately
and show the container or the label. Keep away from incompatibles such as acids.
Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: N/A
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering
controls to keep airborne levels below recommended exposure limits. If user operations
generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below
the exposure limit.
Personal Protection: Safety glasses, lab coat, dust respirator, making sure to use an
approved/certified respirator or equivalent, and gloves.
Page 5 of 10 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
9.
SODIUM BICARBONATE
Ref. No.
MSDS /PD/10_01
Valid for:
2 years from approval
Physical and Chemical Properties
Physical state and appearance: White solid.
Odour: Odourless
Taste: Saline. Alkaline.
Molecular Weight: 84.01g/mole
pH (1% solution/water): N/A
Boiling Point: N/A
Melting Point: N/A
Critical Temperature: N/A
Specific Gravity (Water = 1): 2.159
Vapour Pressure (mmHg): Not applicable.
Vapour Density: N/A
Volatility: N/A
Odour Threshold: N/A
Water/Oil Distribution Coefficient: N/A
Ionicity (in Water): N/A
Dispersion Properties: See solubility in water.
Solubility: The substance is soluble in cold water and slightly soluble in alcohol.
Stability and Reactivity Data
10.
Stability: The product is stable.
Corrosivity: Non-corrosive in presence of glass.
Instability temperature: N/A
Conditions of Instability: Incompatible materials, Moisture. Stable in dry air, but slowly
decomposes in moist air.
Incompatibles: Reactive with acids forming carbon dioxide. Dangerous reaction with
monoammonium phosphate or a sodium-potassium alloy.
Polymerization: Does not occur.
Page 6 of 10 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
11.
SODIUM BICARBONATE
Ref. No.
MSDS /PD/10_01
Valid for:
2 years from approval
Toxicological Information
Toxicity to animals: Acute oral toxicity (LD50): 3360 mg/kg [Mouse].
Effects on humans: N/A. Slightly hazardous in case of skin contact (irritant), of ingestion, of
inhalation.
Acute potential health effects:
- Skin: May cause mild skin irritation.
- Eyes: May cause mild eye irritation.
- Inhalation: May cause respiratory tract irritation. Symptoms may include coughing and
sneezing.
- Ingestion: Symptoms of overexposure to sodium bicarbonate include thirst, abdominal
pain, gastroenteritis, and inflammation of the digestive tract.
Chronic potential health effects:
- Skin: Repeated or prolonged skin contact may cause irritation, drying or cracking of
the skin.
- Ingestion and inhalation: Chronic toxicity usually occurs within 4 to 10 days following
ingestion of very large amounts. Repeated or prolonged ingestion or inhalation of large
amounts may cause metabolic abnormalities, and sodium retention. Metabolic
abnormalities such as acidosis, hypernatraemia, hypochloraemia, alkalosis,
hypocalcaemia, or sodium retention may affect the blood, kidneys, respiration
(cyanosis, apnoea secondary to metabolic acidosis or pulmonary oedema), and
cardiovascular system (tachycardia, hypotension). Severe toxicity may also affect
behaviour/central nervous system/nervous system. Neurological changes may result
from metabolic abnormalities. These may include fatigue, irritability, dizziness, mental
confusion, paraesthesia, seizures, tetany and cerebral oedema.
- Medical Conditions Aggravated by Exposure: Persons with pre-existing skin
conditions might have increased sensitivity. Predisposing conditions that contribute to
a mild alkali syndrome include, renal disease, dehydration, and electrolyte imbalance,
hypertension, sarcoidosis, congestive heart failure, oedema, or other sodium retaining
conditions.
MUTAGENIC EFFECTS: N/A
TERATOGENIC EFFECTS: N/A
DEVELOPMENTAL TOXICITY: N/A
Other information: N/A
Page 7 of 10 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
12.
SODIUM BICARBONATE
Ref. No.
MSDS /PD/10_01
Valid for:
2 years from approval
Ecological Information
Ecotoxicity: N/A 13.
Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with local environmental control
regulations.
14.
Other Information
Created: 9/10/2012
Updated: 17/10/2012
Page 8 of 10 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
15.
SODIUM BICARBONATE
Ref. No.
MSDS /PD/10_01
Valid for:
2 years from approval
References
-
Web.grcc.edu. Material Safety Data Sheet; Sodium bicarbonate [Online]. 2012 [cited
2012
Oct
9].
Available
from:
URL:
http://web.grcc.edu/Pr/msds/facilities/SodiumBicarbonate.pdf
-
Avogadro.com. Material Safety Data Sheets; Sodium bicarbonate [Online]. 2012 [cited
2012
Oct
9].
Available
from:
URL:
http://avogadro.chem.iastate.edu/MSDS/NaHCO3.htm
-
Sciencelab.com. Material Safety Data Sheet; Sodium bicarbonate [Online]. 2005 [cited
2012
Oct
9].
Available
from:
URL:
http://www.sciencelab.com/msds.php?msdsId=9927258
-
Hillbrothers.com. Material Safety Data Sheet; Sodium bicarbonate [Online]. 2012
[cited
2012
Oct
9].
Available
from:
URL:
http://www.hillbrothers.com/msds/pdf/n/sodium-bicarb-pool.pdf
-
Innophos.com. Material Safety Data Sheet; Sodium bicarbonate [Online]. 2012 [cited
2012
Oct
9].
Available
from:
URL:
http://www.innophos.com/__sitedocs/msds/sodium-bicarbonate-e00017-1.pdf
16.
Appendices
N/A Page 9 of 10 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
17.
SODIUM BICARBONATE
Ref. No.
MSDS /PD/10_01
Valid for:
2 years from approval
Revision History
Version Number Amendments/ Reasons for change
01
Initial Release
Page 10 of 10