UNIVERSITY OF MALTA FACULTY OF MEDICINE & SURGERY PHARMACY DEPARTMENT MATERIAL SAFETY DATA SHEET MAGNESIUM TRISILICATE Table of Contents Ref. No. MSDS /PD/4_01 Valid for: 2 years from approval Page 1. Chemical Product 2. Composition and Information on Ingredients 3. Hazards Identification 4. First Aid Measures 5. Fire and Explosion Data 6. Accidental Release Measures 7. Handling and Storage 8. Exposure Controls/ Personal Protection 9. Physical and Chemical Properties 10. Stability and Reactivity Data 11. Toxicological Information 12. Ecological Information 13. Disposal Considerations 14. Other Information 15. References 16. Appendices 17. Revision History Page 1 of 9 2 2 2 3 4 5 5 6 6 7 7 7 7 8 8 8 9 UNIVERSITY OF MALTA FACULTY OF MEDICINE & SURGERY PHARMACY DEPARTMENT MATERIAL SAFETY DATA SHEET MAGNESIUM TRISILICATE 1. Ref. No. MSDS /PD/4_01 Valid for: 2 years from approval Chemical Product Product Name: Magnesium trislicate Chemical name: Magnesium trisilicate Synonyms: N/A Chemical Formula: 2MgO.3SiO3.xH2O 2. Composition and Information on Ingredients Composition: Magnesium trisilicate 100% by weight. Toxicological Data on Ingredients: Magnesium trisilicate LD50: N/A. LC50: N/A. 3. Hazards Identification Potential Acute Health Effects: Very hazardous in case of inhalation, ingestion, and slightly hazardous in case of skin contact (irritant) or eye contact (irritant). Potential Chronic Health Effects: N/A MUTAGENIC EFFECTS: N/A TERATOGENIC EFFECTS: N/A DEVELOPMENTAL TOXICITY: N/A. The substance is toxic to lungs, mucous membranes. Repeated or prolonged exposure to the substance can produce target organ damage. CARCINOGENIC EFFECTS: Page 2 of 9 UNIVERSITY OF MALTA FACULTY OF MEDICINE & SURGERY PHARMACY DEPARTMENT MATERIAL SAFETY DATA SHEET MAGNESIUM TRISILICATE 4. Ref. No. MSDS /PD/4_01 Valid for: 2 years from approval First Aid Measures General measures: N/A Skin contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Serious skin contact: N/A Eye contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Seek medical attention if irritation occurs. Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel and never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. Serious indigestion: N/A Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention. Serious inhalation: N/A Page 3 of 9 UNIVERSITY OF MALTA FACULTY OF MEDICINE & SURGERY PHARMACY DEPARTMENT MATERIAL SAFETY DATA SHEET MAGNESIUM TRISILICATE 5. Ref. No. MSDS /PD/4_01 Valid for: 2 years from approval Fire and Explosion Data Flammability of the Product: Non-flammable. Auto-Ignition Temperature: Not applicable. Flash points: Not applicable. Flammable limits: Not applicable. Products of Combustion: N/A Fire Hazards in Presence of Various Substances: Not applicable. Explosion Hazards in Presence of Various Substances: - Risks of explosion of the product in presence of mechanical impact: N/A. - Risks of explosion of the product in the presence of static discharge: N/A Fire fighting media and Instructions: Not applicable. Special Remarks on Fire Hazards: N/A. Special Remarks on Explosion Hazards: N/A. Page 4 of 9 UNIVERSITY OF MALTA FACULTY OF MEDICINE & SURGERY PHARMACY DEPARTMENT MATERIAL SAFETY DATA SHEET MAGNESIUM TRISILICATE 6. Ref. No. MSDS /PD/4_01 Valid for: 2 years from approval Accidental Release Measures NB: Wear appropriate protective equipment/clothing including gloves before removing any spills. Small spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of the substance according to local and regional authority requirements. Large spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to the substance to evacuate through the sanitary system. 7. Handling and Storage Precautions: Do not breathe dust and wear suitable protective clothing. In the case of insufficient ventilation, wear suitable respiratory equipment, and if you feel unwell, seek medical attention, presenting the container label when possible. Storage: No specific storage is required, but use shelves or cabinets sturdy enough to bear the weight of the chemicals. Be sure that there is no necessary to strain to reach materials, and that shelves are not overloaded. Page 5 of 9 UNIVERSITY OF MALTA FACULTY OF MEDICINE & SURGERY PHARMACY DEPARTMENT MATERIAL SAFETY DATA SHEET MAGNESIUM TRISILICATE Ref. No. MSDS /PD/4_01 Valid for: 2 years from approval 8. Exposure Controls/Personal Protection Airborne Exposure Limits: N/A Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal Protection: Safety glasses, lab coat, dust respirator, making sure to use an approved/certified respirator or equivalent, and gloves. 9. Physical and Chemical Properties Physical state and appearance: White crystalline powder. Odour: Odourless. Taste: N/A Molecular Weight: 260.86 g/mole pH (1% solution/water): Not applicable. Boiling Point: N/A Melting Point: N/A Critical Temperature: N/A Specific Gravity (Water = 1): 2.5 Vapour Pressure (mmHg): Not applicable. Vapour Density: N/A Volatility: N/A Odour Threshold: N/A Water/Oil Distribution Coefficient: N/A Ionicity (in Water): N/A Dispersion Properties: N/A Solubility: Insoluble in cold water Page 6 of 9 UNIVERSITY OF MALTA FACULTY OF MEDICINE & SURGERY PHARMACY DEPARTMENT MATERIAL SAFETY DATA SHEET MAGNESIUM TRISILICATE 10. Ref. No. MSDS /PD/4_01 Valid for: 2 years from approval Stability and Reactivity Data Stability: The product is stable. Corrosivity: Non-corrosive in presence of glass. Instability temperature: N/A Conditions of Instability: N/A Incompatibles: N/A Polymerization: No 11. Toxicological Information Toxicity to animals: LD50: N/A. LC50: N/A Effects on humans: Acute potential health effects: N/A Chronic potential health effects: The substance is toxic to lungs, mucous membranes. MUTAGENIC EFFECTS: N/A TERATOGENIC EFFECTS: N/A DEVELOPMENTAL TOXICITY: N/A Other information: Very hazardous in case of inhalation and ingestion, and slightly hazardous in case of skin contact (irritant). 12. Ecological Information Ecotoxicity: N/A 13. Disposal Considerations Waste Disposal: Disposal should be in accordance with the principles of Duty of Care observing local and national regulations. Page 7 of 9 UNIVERSITY OF MALTA FACULTY OF MEDICINE & SURGERY PHARMACY DEPARTMENT MATERIAL SAFETY DATA SHEET MAGNESIUM TRISILICATE 14. Ref. No. MSDS /PD/4_01 Valid for: 2 years from approval Other Information Created: 9/10/2012 Updated: 16/10/2012 15. References - Jmloveridge.com. Material Safety Data Sheet; Magnesium trislicate [Online]. 2012 [cited 2012 Oct 9]. Available from: URL: http://www.jmloveridge.com/cosh/Magnesium%20Trisilicate.pdf - Anachemia.com. Material Safety Data Sheet; Magnesium trisilicate [Online]. 2012 [cited 2012 Oct 9]. Available from: URL: http://www.anachemia.com/msds/english/5573.pdf - Spectrumchemical.com. Material Safety Data Sheet; Magnesium trislicate [Online]. 2012 [cited 2012 Oct 9]. Available from: URL: https://www.spectrumchemical.com/MSDS/M3220.PDF - Sciencelab.com. Material Safety Data Sheet; Magnesium trisilicate [Online]. 2005 [cited 2012 Oct 9]. Available from: URL: http://www.sciencelab.com/msds.php?msdsId=9924560 16. Appendices N/A Page 8 of 9 UNIVERSITY OF MALTA FACULTY OF MEDICINE & SURGERY PHARMACY DEPARTMENT MATERIAL SAFETY DATA SHEET MAGNESIUM TRISILICATE 17. Ref. No. MSDS /PD/4_01 Valid for: 2 years from approval Revision History Version Number Amendments/ Reasons for change 01 Initial Release Page 9 of 9