Press Bulletin No. 177. 3-21-09-3000 . Kansas State Agricultural College t cumen on cal Do Histori ural Experiment Stati ult as Agric Kans EXPERIMENT STATION VETERINARY DEPARTMENT Swamp Fever or Infectious Anemia of Horses Diagnoses. —It is quite easy to recThis disease has caused considerable loss in the last three years in the ognize the trouble, especially in the southeastern and central portions of advanced stages. The Slow progress Kansas, and is still present in some at the beginning, remittent fever, prosections. It seems to be most preva- gressive emaciation and anemia, unlent during wet seasons, in low lying, impaired or ravenous appetite, stagbadly drained sections, and during the gering gait, and excessive urination summer months. are usually all present to a greater The cause of the disease as given by or less degree. Dr. John R. Mohler, Chief of the Prognosis . — Is very unfavorable, Pathological Division of the Bureau death occurring in from 60 to 80 per of Animal Industry at Washington, cent of the cases. Recovery takes is as follows: place only when treatment is begun “It has been conclusively proven early and when the disease is not too that infectious anemia is produced by acute. an invisible, filterable organism which Treatment . — Is not satisfactory. is transmissible to horses, mules and Absolute rest until fully recovered is asses by subcutaneous inoculation of one of the primary requisites, and blood serum. The virus which is pres- purgatives are to be avoided. For ent in the blood may be transmitted to the fever the B. A. I. recommends an a number of equines in a series of in- antipyretic of quinine 40 grains, acetoculations by injecting either the anilid 2 drams, and powdered nux whole blood, the defibrinated blood, vomica 30 grains, four times daily. or the blood serum which has been Cold water sponge baths and frequent passed through a fine Pasteur filter, copious rectal injections of cold water thus eliminating all the visible forms also aid in reducing the fever. After of organismal life, including bacteria, the fever subsides the following is trypanosoma, piroplasma, etc. This recommended: Grams. virus has also been found to be active “Arsenious acid . . . . . . . . . . . . . . . . . 2 in the carcass of an affected animal Powdered nux vomica . . . . . . . . . . 28 Powdered cinchona bark . . . . . . . 85 twenty-four hours after death. (See page 2.) Powdered gentian root . . . . . . . . . . 110 ument cal Doc tion Histori ural Experiment Sta Kansas Agricult “Following the injection of the infectious principle there is a period of incubation which may extend from ten days to one and one-half months, at the end of which time the onset of the disease is manifested by a rise of temperature. If uncomplicated, the infection runs a chronic course, terminating in death in from two months to one and one-half years, or even longer. The probability of the virus being spread by an intermediate host, such as flies, mosquitoes, internal parasites, etc., is now receiving careful investigation,” Symptoms. — About the first symptoms noticed are a general weakness of the animal, it tires very easily and is not able to do any work. The loss of flesh is apparent in spite of the voracious appetite which the animal has at times. The appetite usually remains good until death, but the feed seems to do the animal no good. The temperature is very irregular. Some days it runs quite high, at times to 107 degrees; again it is below normal. It frequently remains high toward the end of the disease. An animal may have several attacks of the trouble, but each succeeding attack seems to be more severe. The blood becomes thin and the circulation impaired, and frequently there appears a swelling under the chest or abdomen or an enlargement of one or more legs. (See page 1.) Approved: E D . H WE B S T E R, Director. M ANHATTAN , KAN., March 22, 1909. “These should be well mixed and one-half tablespoonful given at each feed to the affected animal. “As in the case of all other infectious diseases, the healthy should be separated from the sick horses, and thorough disinfection of the infected stable, stalls, litter and stable utensils should be carried out in order to prevent the recurrence of the disease. As a disinfectant the compound solution of cresol, carbolic acid or chlorid of lime may be used by mixing six ounces of any one of these chemicals with one gallon of water. One of the approved coal-tar sheep-dips might also be used to advantage in a five per cent solution (six ounces of dip to one gallon of water). The disinfectant solution should be applied liberally to all parts of the stable, and sufficient lime may be added to the solution to make the disinfectant area conspicuous.” Precautions. —From the fact that the disease is more prevalent during wet seasons, it is always best to guard against allowing the animals to graze upon swampy lands or to drink from ponds of stagnant water. The spread of the disease has been traced along creeks from one farm to another, which would suggest avoiding these places also. The draining of low, swampy lands is especially recommended. F. S. SC H O E N L E B E R , Veterinarian.