Tokihiro Yamamoto, M.S., Ph.D.
Clinical Interests
Dr. Yamamoto’s clinical interests include image-guided radiotherapy (IGRT) for managing internal
anatomy motion during treatment of thoracic and abdominal cancers.
Dr. Yamamoto’s main scientific interests focus on advanced anatomic/functional/molecular imaging
for improving therapeutic gain of radiotherapy. His current research projects include the
development and investigation of novel pulmonary functional imaging techniques based on fourdimensional (4D) computed tomography (CT) and xenon CT (Xe-CT), and applications to lung
cancer radiotherapy and beyond.
Specialty
Cancer, Medical Physics, Radiation Oncology
Department
Radiation Oncology
Division
Radiation Oncology
Center/Program Affiliation
Languages
Education
UC Davis Comprehensive Cancer Center
Japanese
M.S., Osaka University, Suita, Osaka, 2004
Ph.D., Osaka University, Suita, Osaka, 2007
B.S., Osaka University, Suita, Osaka, 2002
Fellowships
Board Certifications
Professional Memberships
Stanford University, Stanford, CA, 2011
Japanese Board of Medical Physics (JBMP), 2007
American Association of Physicists in Medicine (AAPM)
American Society for Radiation Oncology (ASTRO)
Japan Society of Medical Physics (JSMP)
Japan Society of Pulmonary Functional Imaging
Japanese Society for Therapeutic Radiology and Oncology (JASTRO)
Honors and Awards
Young Scientist Sponsorship, European Respiratory Society (ERS), 2011
Scientific Presentation Award, International Workshop for Pulmonary Functional Imaging, 2011
John S. Laughlin Science Council Research Symposium, American Association of Physicists in
Medicine (AAPM), 2010
Select Recent Publications
Yamamoto T, Kabus S, von Berg J, Lorenz C, Chung M P, Hong J C, Loo B W, Jr. and Keall P J
Tokihiro Yamamoto, M.S., Ph.D.
2012 Reproducibility of four-dimensional computed tomography-based lung ventilation imaging
Acad Radiol 19 1554-65
Yang J, Yamamoto T, Cho B, Seo Y and Keall P J 2012 The impact of audio-visual biofeedback on
4D PET images: Results of a phantom study Med Phys 39 1046-57
Yamamoto T, Kabus S, Klinder T, Lorenz C, von Berg J, Blaffert T, Loo B W, Jr. and Keall P J 2011
The investigation of four-dimensional computed tomography-based pulmonary ventilation imaging
in patients with emphysematous lung regions Phys Med Biol 56 2279-98
Yamamoto T, Kabus S, Klinder T, von Berg J, Lorenz C, Loo B W, Jr. and Keall P J 2011 Fourdimensional computed tomography pulmonary ventilation images vary with deformable image
registration algorithms and metrics Med Phys 38 1348-58
Yamamoto T, Kabus S, von Berg J, Lorenz C and Keall P J 2011 Impact of four-dimensional
computed tomography pulmonary ventilation imaging-based functional avoidance for lung cancer
radiotherapy Int J Radiat Oncol Biol Phys 79 279-88
Yamamoto T, Kabus S, von Berg J, Lorenz C, Goris M L, Loo B W, Jr. and Keall P J 2010 Evaluation
of four-dimensional (4D) computed tomography (CT) pulmonary ventilation imaging by
comparison with single photon emission computed tomography (SPECT) scans for a lung cancer
patient. In: Proc. of the Third International Workshop on Pulmonary Image Analysis, MICCAI
2010, 117-128 (URL: www.lungworkshop.org/2010/ proc2010/yamamoto.pdf)
Cui G, Gopalan S, Yamamoto T, Berger J, Maxim P G and Keall P J 2010 Commissioning and
quality assurance for a regular respiration system based on audiovisual biofeedback J Appl Clin
Med Phys 11 42-56
Mukumoto N, Tsujii K, Saito S, Yasunaga M, Takegawa H, Yamamoto T, Numasaki H and Teshima
T 2009 A preliminary study of in-house Monte Carlo simulations: an integrated Monte Carlo
verification system Int J Radiat Oncol Biol Phys 75 571-9
Yamamoto T, Langner U, Loo B W, Jr., Shen J and Keall P J 2008 Retrospective analysis of artifacts
in four-dimensional CT images of 50 abdominal and thoracic radiotherapy patients Int J Radiat
Oncol Biol Phys 72 1250-8
Kabus S, von Berg J, Yamamoto T, Opfer R and Keall P J 2008 Lung ventilation estimation based
on 4D-CT imaging. In: Proc. of the First International Workshop on Pulmonary Image Analysis,
MICCAI 2008, (New York, NY pp 73-81). (URL: www. lungworkshop.org/2008/proc2008/8kabus.pdf)
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