Summary of the Roundtable on Industrial Biotechnology in Poland 3 July 2008, Warsaw INTRODUCTION 3 ROUNDTABLE ON INDUSTRIAL BIOTECHNOLOGY IN POLAND 4 SWOT ANALYSIS OF (INDUSTRIAL) BIOTECHNOLOGY IN POLAND 7 ANNEXES 8 2 Introduction The roundtable on industrial biotechnology in Poland took place on 3 July 2008 in Warsaw (Ministry of Science and Higher Education). The event was initiated by EuropaBio in the framework of the European Technology Platform on Sustainable Chemistry - “SusChem”. The roundtable has been locally organised by Ms Bożena Podlaska FP7 National Contact Point for BIO and Prof. Stanisław Bielecki from the Technical University of Lodz. Participants to the roundtable were representatives from academia, enterprises, development agencies and ministries/government bodies with an interest in the field of biotechnology (see Annexes). 3 Roundtable on industrial biotechnology in Poland • Stanisław Bielecki (Technical University of Lodz) and Stefan Malepszy (Warsaw University of Life Sciences and Coresponding Member of the Polish Academy of Sciences) opened the roundtable with a short presentation of the objectives and the programme. The said that industrial biotechnology is considerd in Poland a sector in evolution and still at the „start stage“ It is still not yet sufficiently implemented in industry to become sector in itself. It is mainly implemented in academia. • A tour de table was organised to let participants introduce themselves. • Stanisław Bielecki (Technical University of Lodz) presented a general overview of industrial biotechnology in Poland. From his point of view, Poland has a very long tradition in industrial biotechnology at academia level. He firslty contextualised industrial biotechnology presenting the Koln vision paper that was developed under the German Presidency. This vision estimates that in 2030, bioproducts will have a 1/3 share, worth 300 billion euros, of industrial production. The paper also states that the combination of plant breeding and industrial biotechnology will constitute the basis of the knowledge based-bioeconomy. Then he addressed research in the field of industrial biotechnology and biotechnoly in Poland. In 2005, 2,7% (155 million PLN) of the state budget was affected to R&D, which represents a small funding. 4% of the R&D budget is affected to biotechnology. Around 50% of biotech R&D projects were realised in collaboration with industry (50% in biopharma, 30 in agribiotech and 15% in industrial biotech). In March 2008, the Polish government approved an actions plan towards the development of industrial biotechnology in Poland. This plans consists of 2 axes: research programmes as well as policies and regulations supporting industrial biotech (cf. Slides 11 & 12). He presented the state of industrial biotechnology enterprises in Poland and made a SWOT analysis of industrial biotechnology in Poland (see below). There are 20 enterprises active in the field of biotechnology of which 8 in industrial biotechnoloy. These industries are using very differenciated material base and dedicate only a very small part of their turn over to R&D. Finally, he presented the different platforms, groups and associations active in industrial biotechnology in Poland, notably the Polish platform for Biotechnology which is member of the European Technology Platform for Sustainable Chemistry (SusChem). • Andrzej Anioł (Plant Breeding and Acclimatization Institute at Radzików) presented the role of agrobiotechnology as a source for industrial biotechnology. He firstly contextualised biotechnology in the time, saying that modern biotechnology appeared in 1957. Then, he presented the three targets for research on non-food plant production: - Develop advanced plant-based raw materials and pharmaceuticals (reduce the price of biomass) - Develop plants as energy production systems - Convert plants into production factories He pointed out that 13 years is the approximate timeline for the development of new transgenic cultivation • Krzysztof Biernat (Polish Technology Platform for Biofuels) 4 • Jerzy Majchrzak (Polish Chamber of Chemical Industry & Polish Technology Platform for Sustainable Chemistry) presented the opportunities and limitations of using industrial biotechnology in specialty chemicals. The first question he pointed out is: Can biomass significantly substitute fossil feedstock? Regarding feedstock, he also raised the question of prices. He then explained the different pathways of biomass conversion. He stressed the general applicability of renewables in the chemical industry as there are many possible applications; a huge variety in technology but noted the need for highly efficient processes to be competitive vs fossil feedstock. He also stressed that competitive raw materials are available, but non-availability of processes limits the potential of BioRenewables He then presented an example of renewable sources use by Evonik Industry (production of emollient esters based on enzymatic esterification). Finally, he stressed that access to sugar world market is key to EU biotech industry as the price for bio-chemicals based on renewable resources is strongly linked to the price of its feedstock He concluded saying that: - Wrong incentives (e.g. subsidies or regulation) in agriculture can divert biomaterial into other applications - Biomaterial has a global market with world market prices, fair competition is only possible if open access to these feedstock markets is guaranteed - It is essential to Make R&D funds available for pre-competitive research in industry - Use of GMOs in production processes is necessary to increase process efficiency, avoid bureaucratic burden and strive for globally competitive conditions - Environmental impact through intensified agricultural use needs to be evaluated together with CO2- saving potential and other GHG emissions to assess overall ecoefficiency - Logistic in bio-material availability is crucial for economically interesting “economy of scale”. • Alfredo Aguilar (DG Research, European Commission) presented biotechnology and the th Knowledge-Based Bio-Economy (KBBE) in the 7 Framework Programme for Research and Development. More specifically, he presented o The major trends/challenges affecting bio-economy today and the current situation. He said that science is not only to make university work but to further develop, products and increase or quality of life o The European Life Sciences and Biotechnology Strategy for Europe and its review in 2007. o A general picture of FP7 as well as KBBE thematic that are covered by FP7. o Some statistics on the first and second calls in the field of biotechnology as well as the way work programmes are prepared and the evaluation processes rd o A first draft of the 3 call that will probably be presented officially on 3 September 2008 (cf. presentation of the European Commission). o The different platforms and networks related to biotechnology in Europe. He notably stressed the fact that that success will depend on coordination and mobilisation of all actors. o The lead market initiative for bio-based products that has been announced by the Commission in December 2007. 5 • Dirk Carrez (EuropaBio) presented the work done by the industrial biotech section of SusChem: an European Strategic Research and Policy Agenda for Industrial Biotechnology. He firstly introduced the bio-based economy by presenting its concept (integrated biorefinery, industrial biotech in the chemicals system) as well as the barriers and drivers for bio-based products in Europe. He also presented some market figures for bio-based products in Europe (it is expect to reach 10% of chemical sales by 2010 according a McKinsey study). He then presented the Vision, Research and Policy Agendas developed in the framework of the Technology Platform on Sustainable Chemistry (SusChem) which objectives are to boost sustainable chemistry, industrial biotechnology and chemical engineering research, development and innovation in Europe. The strategic research agenda looks into the future impact of Industrial Biotechnology and lays out the major research areas which must be addressed to move from a flourishing set of scientific disciplines to a major contributor to a future knowledge-based economy. It focuses in particular on the research needed to underpin three broad topics: biomass, bioprocesses and bio-products, including bio-energy. The Policy Agenda developed by SusChem aims to establish a coherent European Policy Agenda for the KBBE (he showed several slides with all legislations and policies having and impact today on the sector). The Policy agenda also wants to stimulate and support innovation in plant science and industrial biotechnology; to promote production and use of bio-based products and processes; to create awareness amongst all stakeholders and to improve investment in IB SME’s Finally, he introduced the Lead Market Initiative (LMI) that was adopted in December 2007 by the European Commission and endorsed by the Council in March 2008. The LMI for Biobased products aims at turning industrial production to a more sustainable way and builds on key European strength: excellent biotechnology research base; strong chemical and enzyme industries; availability of biological resources; strong political support for advanced concepts of sustainable production. The second half of the roundtable was dedicated to discussion on concrete recommendations and actions aiming at further developing and supporting industrial biotechnology in Poland. Discussions took place on the basis of recommendations that had been prepared by Stanisław Bielecki. More details below in “recommendations” 6 SWOT analysis of (industrial) biotechnology in Poland Strengths - Weaknesses - Diversified research areas covered by research institutions Knowledge and skills of Polish biotechnologists High quality education Raw materials base (developed agricultural sector) Environment (diversity and low level of degradation) - - Opportunities - Development of science in chosen IB areas (action plan) High educational level and attitude of students Changes in law regulations connected to scientific research aimed at protecting and stimulation of research activities Political declarations of improvement of mechanisms supporting investments in new technologies Support to the development of industrial clusters by local and State authorities Low labour costs (including research personnel costs) Development of sectors connected with IB development Lack of financing support (not enough VC) Low demand for new high technologies from Polish industry Inadequate or unused research infrastructure Lack of information flow mechanisms among groups dealing with IB Small participation of applied research sector to IB Inadequate support of IB by State authorities Shortage of adequately educated managers to support the commercialization of biotechnological products Threats - Ever decreasing and insufficient financing of scientific research Lack of investments in research and new technologies connected with IB in enterprises Foreign entities’ competition which is often aimed at taking over Polish entities Emigration of young, educated personnel 7 Annexes Thursday 3 July 2008 – Roundtable on industrial biotechnology Place: Ministry of Science and Higher Education, in room 117 (first floor), Warsaw 9:30-10:00 10:00-10:10 Welcome coffee Welcome and opening 10:10-10:30 10:30-10:50 Presentation of participants Industrial Biotechnology in Poland 10:50-11:10 Agrobiotechnology as a source of materials for industrial biotech 11:10-11:30 Implementation of biofuels production in Poland 11:30-11:50 Biotechnology in Polish Chemical Industry Ministry of Science and Higher Education Prof. Stanisław Bielecki, Technical University of Lodz and Polish Technology Platform for Biotechnology Prof. Andrzej Anioł, Plant Breeding and Acclimatization Institute at Radzików Dr. Krzysztof Biernat, Polish Technology Platform for Biofuels, Warsaw Jerzy Majchrzak, Director of Polish Chamber of Chemical Industry, Polish Technology Platform for Sustainable Chemistry Coffee Break 12:15-12:40 Biotechnology in FP7 and KBBE 12:40-13:15 SusChem: Strategic Research Agenda & Policy Agenda Dr. Alfredo Aguilar, European Commission (DG Research) Dr. Dirk Carrez, EuropaBio Lunch 14:30-17:00 Discussion on specific action for development of industrial biotechnology in Poland All 8