Classification: UNCLASSIFIED
Caveats: NONE
Defense Health Program
Department of Defense Peer Reviewed Medical Research Program
Funding Opportunities for Fiscal Year 2015
The Fiscal Year 2015 (FY15) Defense Appropriations Act provides $247.5 million to the Department of Defense
Peer Reviewed Medical Research Program (PRMRP). The vision of the PRMRP is to improve the health and wellbeing of all military Service Members, Veterans, and beneficiaries. The PRMRP challenges the scientific and clinical
communities to address one of the FY15 congressionally directed topic areas with original ideas that foster new directions
in basic science and translational research; novel product development leading to improved therapeutic or diagnostic
tools; synergistic, multidisciplinary research program; or clinical trials that address an immediate clinical need.
As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency, Research,
Development, and Acquisition (DHA RDA) Directorate manages and executes the Defense Health Program (DHP)
Research, Development, Test, and Evaluation (RDT&E) appropriation. The executing agent for the anticipated Program
Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP).
FY15 PRMRP Program Announcements and General Application Instructions are posted on Grants.gov.
Military Relevance: Relevance to the healthcare needs of the military Service Members, Veterans, and beneficiaries is a
key feature of each FY15 PRMRP award mechanism.
Clinical Trial Award – Pre-application due June 18, 2015
Assistant Professor level or above (or equivalent)
• Supports the rapid implementation of clinical trials of novel interventions with the potential to have a significant
impact on patient care in the topic area(s) of interest
• Proposed projects may range from small proof-of-concept trials through large-scale, definitive trials
• Investigational New Drug or Investigational Device Exemption applications, if needed, should be submitted to the
Food and Drug Administration before the PRMRP Grants.gov application submission deadline
Preproposal submission is required; application submission is by invitation only
• Funding limit not defined; requested funding must be appropriate for the scope of work proposed
• Maximum period of performance is 5 years
Discovery Award – Letter of Intent due June 25, 2015
All Investigators
• Supports the exploration of a highly innovative new concept or untested theory
• Not intended to support the logical progression of an already established line of questioning
• Clinical trials will not be funded
Reviewers will be blinded to the identity of the PI, collaborators, and their organization(s)
• Maximum of $200,000 for direct costs (plus indirect costs)
• Maximum period of performance is 18 months
Focused Program Award – Pre-application due June 18, 2015
Full Professor level or above (or equivalent)
• Restricted to the topic areas of Acupuncture, Advanced Prosthetics, Burn Pit Exposure, Cardiovascular Heart
Disease, Congenital Heart Disease, Focal Segmental Glomerulosclerosis, Healthcare-acquired Infection
Reduction, Hepatitis B, Hydrocephalus, Integrative Medicine, Metals Toxicology, Mitochondrial Disease,
Nanomaterials for Bone Regeneration, Osteoarthritis, Pathogen-inactivated Dried Plasma, Pulmonary Fibrosis,
Psychotropic Medications, Respiratory Health, Sleep Disorders, Vascular Malformations, and Women’s Heart
Disease
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Supports a synergistic, multidisciplinary research program of at least four distinct but complementary projects
addressing an overarching goal in one of the topic areas listed directly above
Projects should work together to answer critical questions, resolve differing hypotheses, and translate laboratory
findings to clinical applications
Projects may range from exploratory/hypothesis-developing through small-scale clinical trials that together will
address the overarching goal/question
Research team of highly qualified, multidisciplinary project leaders should be led by a Principal Investigator with
demonstrated success in directing large, focused projects
Preproposal submission is required; application submission is by invitation only
• Maximum of $10 million for total costs (includes direct and indirect costs)
• Maximum period of performance is 5 years
Investigator-Initiated Research Award – Pre-application due June 11/2015
Assistant Professor level or above (or equivalent)
• Supports research that will make an original and important contribution to the field of research or patient care in
the topic area(s) of interest
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Partnering Principal Investigator (PI) Option available
Clinical trials will not be funded
Preproposal submission is required; application submission is by invitation only
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Maximum of $1.2 million for direct costs (plus indirect costs)
Maximum of $1.5 million for direct costs (plus indirect costs) for applications including a Partnering PI Option
Maximum period of performance is 3 years
Technology/ Therapeutic Development Award – Pre-application due June 11, 2015
Assistant Professor level or above (or equivalent)
• Supports the development of diagnostics or therapies that have the potential to make a strong impact on patient
care in the topic area(s) of interest
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Product-oriented: device, drug, clinical guidelines
Clinical trials will not be funded
Preproposal submission is required; application submission is by invitation only
• Maximum of $1.8 million for direct costs (plus indirect costs)
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Maximum period of performance is 3 years
A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal
(eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final Program
Announcements and General Application Instructions that will be available for electronic downloading from the Grants.gov
website. The application package containing the required forms for each award mechanism can be found on
Grants.gov. A listing of all CDMRP funding opportunities can be obtained on the Grants.gov website by performing a
basic search using CFDA Number 12.420.
Applications must be submitted through the federal government’s single-entry portal, Grants.gov. Submission deadlines
are not available until the Program Announcements are released. Requests for email notification of the Program
Announcements release may be sent to help@cdmrp.org.
For more information about the PRMRP or other CDMRP-administered programs, please visit the CDMRP website
(http://cdmrp.army.mil).
Point of Contact: help@eBRAP.org
301-682-5507