COBRE Phase III: Novel Approaches for the Control of Microbial Pathogens
Request for Pilot Project Applications
Overview:
Applications are requested for up to $55,000 for pilot projects to be funded by the COBRE grant entitled Novel
Approaches for the Control of Microbial Pathogens. We plan to fund two 2-year pilot project applications. The
second year of funding is contingent upon review of progress at the annual External Advisory Committee
Meeting, submission of all required reporting information, and submission of at least one R01 or R21
application during the first year of funding.
Letter of Intent Submission Deadline:
January 2, 2015
Application Submission Deadline:
February 20, 2015
Funding Dates: August 1, 2015 – July 31, 2017
Eligibility:
Research must fall within the area of the central theme of the COBRE program. The research theme is
centered on mechanisms inhibiting replication of pathogenic microbes, with the long-term goal of controlling
infectious diseases important in human health.
A. Investigators should not have received prior R01-type support from the NIH or other institutions
(such as American Heart Association, American Cancer Society, NSF, DOD) or if the investigator
has R01-type support, the research proposed for COBRE support should have a different focus
and specific aims from the funded project.
B. Eligible participants include tenured and tenure-track faculty at the PhD granting institutions in the
state of Kansas.
C. At least one aim of the pilot project proposal must use the existing flow cytometry core.
Award Amount:
We will fund two awards of up to $55,000 in direct costs during the first year of funding. Resubmission
applications are welcome. Junior faculty should include a mentor and additional salary support for the mentor
will be provided and should not be included in the $55,000 budget. No carryover of funds between grant years
will be allowed. All applications should be written for two years of funding.
Pilot Project Requirements:
1. Letter of Intent: Deadline - January 2, 2015; Should be emailed to Elizabeth Jenkins, ejenkins2@kumc.edu
A letter of intent is required and should include the following information:
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PI’s name and contact information
Title of the proposed application
Statement of relevance to the COBRE theme
Scientific Abstract
List of 5 potential reviewers and their complete contact information. Reviewers must be outside of
the state of Kansas. For resubmission applications, please select 2 new potential reviewers.
2. Full Pilot Project Application: Deadline February 20, 2015
Pilot project applications should include the following sections:
A. Form Page 1: Institutional Face Page
For non KUMC applications, face page should be signed by your appropriate administrative official.
For KUMC applications, the Department Chairman should sign the face page.
B. Form Page 2: Summary, Relevance, Project/Performance Sites, Senior/Key Personnel, Other
Significant Contributors, and Human Embryonic Stem Cells
C. Form Page 4: Detailed Budget for Initial Budget Period
Pilot project budgets should be for a total of $55,000 direct costs.
F&A at KU Lawrence and KSU should be included in the budget in addition to the $55,000 direct costs.
D. Biographical Sketch for PI
E. Biographical Sketch for Proposed Mentor (Junior Faculty Only)
F. Other Support Page for PI
G. Other Support Page for Proposed Mentor (Junior Faculty Only)
H. Resources Page –The applicant should also include a section describing what he/she would do with
a second year of funding. In addition, he/she should include a statement of how this will turn into an
extramural application.
I. Introduction to the Revised Application (resubmission applications only)
J. Specific Aims Page
K. Research Strategy Section – 6 pages
L. Bibliography and References Cited
M. Additional Sections as Required: Biohazards, Human Subjects, Vertebrate Animals, Select Agent
Research, Resource Sharing Plan
N. Letter of Support from your Proposed Mentor Agreeing to serve as a Mentor on your COBRE pilot
project (Junior Faculty Only)
O. Checklist Form Page (Non-KUMC applications only)
Please use the PHS 398 form pages for submission of your application. Updated application form pages are
located at http://grants.nih.gov/grants/funding/phs398/phs398.html.
All applications should be submitted as a PDF file to Elizabeth Jenkins via email (ejenkins2@kumc.edu) and a
hard copy should be sent to her at Elizabeth Jenkins, Department of Microbiology, MSN 3029, 3901 Rainbow
Boulevard, Kansas City, Kansas 66160, Phone 913-588-7012 (campus delivery address 3025 Wahl Hall
West).
3. Institutional Approval: All applications require approval by the appropriate administrative officials at the
respective institution in which the faculty member is based prior to submission. A signed PHS 398 face page is
acceptable to meet this requirement (Department Chair for KUMC applications and appropriate administrative
official for non-KUMC applications).
4. Assurances of Compliance: Proposals selected for funding will be required to have an assurance of
compliance with regulations stipulated by any appropriate institutional committees, including Institutional
Animal Care and Use, Biohazards, Institutional Review Board for Human Studies, and Radiation Safety.
5. Allowable costs: Allowable costs include PI salary up to 5% effort, salary for research personnel, tuition and
fees for graduate students, research supplies, technical assistance, travel when necessary to carry out the
proposed research program, and publication costs.
Travel to national or international meetings to present data related to the pilot project is allowable provided that
the pilot project application budget justification includes the meeting information. Equipment may be allowable
if required specifically for the proposed pilot project. Applicants should include a justification for equipment in
the budget justification and price quote. Application reviewers will determine the necessity of the equipment for
the proposed pilot project.
6. Unallowable costs include construction or maintenance of buildings, renovations, therapeutic equipment,
consortium overhead costs to other institutions, secretarial and telephone services, office furniture, office
equipment, office supplies, dues and memberships in scientific societies, and equipment not specifically
requested in the budget justification and approved by application reviewers.
7. Additional Requirements:
A. When an awardee submits subsequent grant applications, he/she is expected to acknowledge
information on KUMC COBRE funding. If the subsequent grant application receives funding, the
awardee must provide written notification to Elizabeth Jenkins of the type and amount of funding. At
the time of funding, current KUMC COBRE funding will be re-evaluated.
B. Publications resulting from research supported by the KUMC COBRE should cite COBRE funding
by including the grant number P30 GM103326.
C. All pilot project recipients must submit at least one R01 or R21 application to the NIH during the first
year funding of the pilot project in order to be eligible for a second year of funding. .
D. Pilot project recipients are required to provide information needed to complete the Annual Progress
Report. Failure to provide information will result in disqualification for a second year of funding.
E. Pilot project recipients are required to attend and present their research at two mandatory meetings.
One will be an internal meeting in the fall with the internal advisory committee. The second meeting will
also include our external advisory committee where all projects will be reviewed and evaluated for a
second year of funding. This meeting will occur in the spring.
Questions:
Administrative and Budget Questions:
Elizabeth Jenkins, COBRE Administrator, 913-588-7012, ejenkins2@kumc.edu
Project Eligibility and Scientific Questions:
Edward Stephens, PhD, COBRE Pilot Project Director, 913-588-7057, estephen@kumc.edu
Flow Cytometry Core Questions:
Thomas Yankee, PharmD, PhD, Scientific Director of the Flow Cytometry Core, 913-588-2507,
tyankee@kumc.edu