NHS REC application flowchart Researcher develops proposal and populates the IRAS form Researcher sends near final draft for review to relevant RSS Officer, and the content is finalised Researcher books in with the NHS REC and is given a reference to add to the IRAS form. NB: The REC allows 4 working days from registration to the submission of the application Final version of the IRAS form is authorised electronically* by the Chief Investigator, which is then routed to Peter Hedges for sign off as Sponsor Researcher then sends the hard copies to the NHS REC and awaits a confirmation of validity, and the REC meeting details *Projects that fall under the governance of legislation such as Drug Trials and research involving the collection; use of Human Tissue must have wet ink signatures.