International Conference on Global Trends in Engineering, Technology and Management (ICGTETM-2016) A Review on Brain Tumor Segmentation Techniques for MRI Images Jinal A. Shah#1, S. R. Suralkar*2, #1ME Final year student *2 HOD of Electronics & Telecommunication dept.,,SSBTs COET Bambhori,Jalgaon (India) Abstract— Increase in fatal rates because of the Brain tumor is an alarm for an efficient Image segmentation. This has become one of the crucial tasks in medical image analysis and is often the first and the most critical step in a good deal of clinical diagnosis. In brain MRI analysis, image segmentation is commonly used for measuring and visualizing the brain’s anatomical structures, for analyzing brain abnormalities and the extent of tumor, for delineating pathological sections, and for surgical planning and image-guided interventions. Bearing this in mind, an automatic segmentation of brain MR images is needed to correctly segment White Matter (WM), Gray Matter (GM) and Cerebrospinal Fluid (CSF) tissues of brain in a shorter span of time. The accurate segmentation is essential, otherwise the wrong identification of disease can lead to severe consequences. Till date, various segmentation techniques of different accuracy and degree of complexity have been developed and reported in the literature.In this paper, we review the most popular methods commonly used for brain MRI segmentation. Taking into account the aforementioned challenges, we first introduce the basic concepts of image segmentation followed by some conventional methods in brief. Comparison of Segmentation method table which focuses towards highlighting the strengths and limitations of the earlier proposed segmentation techniques discussed in the literature. Besides summarizing the literature, a critical evaluation of the surveyed literature is also provided which reveals new facets of research. However, articulating a new technique is beyond the scope of this paper. Keywords—Brain Tumor Detection, Medical Image Processing, Segmentation, MRI, Fuzzy C Means Clustering I INTRODUCTION Over the last few decades, the rapid development of noninvasive brain imaging technologies has given a new wings in analyzing and studying the brain anatomy and function. Enormous progress in accessing injury in brain and exploring brain anatomy has been made using magnetic resonance imaging (MRI). The advances in brain MR imaging have also ISSN: 2231-5381 provided large amount of data availing an increasingly high level of quality. The analysis of these large and complex MRI datasets has tedious and complex task for clinicians, who use manual method to extract important information. This manual analysis is usually time-consuming and prone to errors due to various inter- or intra operator variability studies. These complexities in brain MRI data analysis required inventions in computer-aided methods to improve disease diagnosis and testing. These days, computerized methods for MR image segmentation, registration, and visualization have been widely used to assist doctors in qualitative diagnosis. [24][21][20] Brain MRI segmentation is an essential task in many clinical applications as it influences the outcome of the entire analysis.For example, MRI segmentation is commonly used for measuring and visualizing various brain structures, for delineating lesions, for analysing brain development, and for image-guided interventions and surgical planning. This diversity in image processing applications has led to development of various segmentation methods of different accuracy and degree of complexity. [24][23] Image Segmentation is an image processing process which aims to partition an image into homogeneous regions composed of pixels with the same characteristics according to predefined criteria. Many methods of image segmentation requires the adjustment of several control parameters to obtain good results. The purpose of image segmentationis to divide an image into a set of semantically meaningful,homogeneous, and non-overlapping regions of similarattributes such as intensity, depth, color, or texture. Thesegmentation result is either an image of labels identifyingeach homogeneous region or a set of contours which describethe region boundaries. [24] Most of the work available by the scholars has focused on 2D images. To segment the 3D image which is generally obtained from a series of MRI images, each image ―slice‖ is segmented individually in a ―slice-by-slice‖ manner. Method of slicing always need post processing to connect segmented 2D slices into 3D volume. Still, the resultingsegmentation http://www.ijettjournal.org Page 323 International Conference on Global Trends in Engineering, Technology and Management (ICGTETM-2016) can contain inconsistencies and non-smooth surface because of important anatomical information omitted in the process to get 3D space. Thus, the need arises to the development of 3D segmentationalgorithms for more accurate segmentation ofvolumetric imagery. The importantdifference between 2D and3D image segmentation is in the processing elements, pixels/voxels, respectively, and their 2D or 3D neighborhoodsoverwhich image features are calculated.[24][23] This paper includes, standard methods commonly used for brain MRI segmentation in section II. Main literature survey of some papers in section III followed by section IV, critical evaluation, table on comparison of segmentation methods of brain tumor in which, we have highlighted differences between them and discuss their benefits and limitations in the table 1and then in section V we deduce a conclusion based on our studies on the literature on the topic mentioned above. II CONVENTIONAL METHODS A wide variety of segmentation methodshas been proposed but still there is no standard approach which results efficiently. Few of these methods are briefly listed below: Thresolding: It is simplest and the oldest method of image segmentation. It is based on the assumption that adjacent pixels whose value lies within a certain range belong to the same class which gives good segmentation of images that include only two opposite components can be obtained. [25]Threshold based image segmentation are Global, Local and Adaptive Thresholding. The key parameter is the choice of selecting threshold value T. This approach helps in the proper detection of the region of interest. The main limitation, only two classes are generated and it cannot be used for multi-channel images. It is not capable of exploiting the information provided by MRI. It approach is sensitive to noise and intensity homogeneities. Region Growing: For image segmentation region growing method is a well-developed technique. Based on some predefined criteria this method extracts region of interest. This is based on intensity information or edges in the image. [25]It starts with a seed, which is selected in the centre region of interest. During the region growing state, pixels in the neighbor of seed are added to region based on homogeneity criteria thereby resulting in a connected region. This methodis sensitive to noise, causing extracted regions to have holes or even become disconnected. These problems can be removed using a homotopic region-growing algorithm. Watershed segmentation:It can be explained by a metaphor based on the behavior of water in a ISSN: 2231-5381 landscape. [19] When it rains, drops of water falling in different regions will follow the landscape downhill. For each valley there will be a region from which all water drains into it. At points where water comes from different basins meets, dams will be built. The process is stop, when the water level reaches the highest peak in the landscape. As a result, the landscape is partitioned into regions separated by dams, called watershed lines. Some researchers used multi-scale watershed transformation to segment brain tumors Kmeans clustering: The K-means clustering algorithm clusters data by iteratively computing a mean intensity for each class and segmenting the image by classifying each pixel in the class with the closest mean. [25]This is also called as hard segmentation. A hard segmentation forces a decision of whether a pixel is inside or outside the object. Fuzzy C –Means(FCM): Segmentations that allow regions or classes to overlap are called soft segmentations. Soft segmentations are important in medical imaging because of partial volume effects, where multiple tissues contribute to a single pixel or voxel resulting in a blurring of intensity across boundaries.[25][19] The main objective is to develop an FCM algorithm for distributing the clusters such that it obtains group of clusters minimizes the dissimilar elements in each cluster .It classifies pixels of an image data set into clusters based on Euclidean distance of a pixel from the center of the least distant cluster. Markov Random Field Algorithm (MRF): It is a type of unsupervised clustering method.[26]It provides integration of clustering process with spatial information of pixels. It reduces the problem of clusters overlapping and noise effect. Classifier methods: supervised methods are pattern recognition techniques that partition a feature space derived from the image by using data with known labels.[25] A simple classifier is the nearestneighbor classifier, in which each pixel is classified in the same class as the training datum with the closest intensity. The k-nearest-neighbor classifier is a generalization of this approach. Support Vector Regression (SVR): It has the ability of learning the nonlinear distribution of the image data without prior knowledge,[19] via the automatic procedure of SVM parameters training and an implicit learning kernel and achieved better segmentation results for the extraction of the brain tumors, compared to the fuzzy clustering method. Guassian Mixture Model: Here the voxels intensity in each target region are modelled by a Guassian distribution and the GMM parameters are usually estimated by maximizing the likelihood of the observed image via the EM algorithm. On the other http://www.ijettjournal.org Page 324 International Conference on Global Trends in Engineering, Technology and Management (ICGTETM-2016) hand, statistical methods often relied on Gaussian assumptions in most cases, using which for modelling the underlying distributions. Bayesian inference has been commonly applied to classify the tissue with MRI.[25][26] Many modified version of the mixture model algorithms had been proposed. There are also many literatures using statistical mixture modelling with expectation-maximization algorithm includes. II LITERATURE REVIEW In this section, review of the selected literature on image segmentation techniques and their usage is mentioned. The main purpose is to highlight key strengths and limitations to these techniques. correct classification. It requires far fewer iterations to converge as compared to EM & FCM.As it is capability to deal with noise, it produceslittle better but noticeable results than EM.BCFCM outperformed the FCM on both simulated and real MRI images. However, FCM has the advantage of working for vectors of intensities whereas the BCFCM is limited to single-feature inputs.Results presented are preliminary and need proper clinical evaluation. However, this method involves phantom measurement based on global corrections for image non-uniformity. The author claims, further work is needed for localized measurement like impact on tumor boundary or volume determinations. Yongyue Zhang et al. [1] paper shows, use of Hidden Markov Random Field (HMRF) model for segmenting Brain MRI by using ExpectationMaximization algorithm.As it has the ability to encode both the statistical and spatial properties of an image, HMRF model is flexible for image modeling.In this paper, author claims, the HMRF-EM method overcomes almost all the drawbacks associated with FM-EM method. The experimental results prove that HMRF-EM produced promising results even with high level of noise, low image quality and large number of classes. A key limitation of this research is that preliminary estimations based on threshold are purely heuristic. However, in case of high invariability of brain MRI, it fails to generate perfect results, particularly in terms of contrast between brain tissues and intensity ranges and this will lead inaccuracy in EM segmentation. Apart from this the proposed method is time consuming and inaccurate most of the times. However, it can obtain slightly good speed by utilizing ICM deterministic method. Mohammed F. Tolba et al. [3] in their paper proposed a new segmentation algorithm for MRI brain image, which is based on EM algorithm and the multiresolution analysis of images, known as Gaussian multi-resolution EM algorithm. The evidence from experiments result show that performance of the proposed technique is much better than the conventional EM algorithm.To overcome the issues mentioned, an algorithm is proposed named GMEM. Merit of the proposed method that it is less sensitive to the noise level and can be used for noisy images. Additionally, accurate results can be obtained, using GMEM algorithm many other medical imaging techniques.The authors argue that more reliable segmentation algorithm can be formulated using advanced scientific techniques, such as data fusion.However, a limitation to this technique is that when the GMEM algorithm is applied to pixel laying on the boundaries between classes or on edges, generates many misclassified pixels. Mohamed N. Ahmed et al. [2] present customized algorithm for fuzzy segmentation of MRI data along with the estimation of intensity inhomogeneities using fuzzy logic. MRI intensity inhomogeneities can lead to imperfections in the radiofrequency coils or to problems associated with the acquisition sequences. The result is a slowly varying shading artifact (noise) over the image that can produce errors with conventional intensity-based classification.The proposed algorithm is modeled by modifying in the objective function of the standard fuzzy c-means algorithm to compensateinhomogeneities and to allow the labeling of a pixel to be influenced by the labels in its immediate neighborhood. This neighborhood effect acts as a regularizer and biases the solution toward piecewise in-homogeneous labelings. Experimental results prove the evidence of effectiveness and efficiency on both synthetic images and MR data. From this we deduce that the regularization can overcome the major drawback of FCM in-homogeneities. The major contribution of proposed work is the introduction of a BCFCM algorithm which is faster to converge to the Li et al. [4] in their paper showed that many vision-related processing tasks such as edge detection, image segmentation and stereo matching are not possible to achieve in optical lenses that have long focal lengths which have a limited depth of field. Previously, work has been done for this mechanism, one of which is wavelet-based image fusion. According to the proposed method, collect several source images with different focuses of the same scene and then process it with the discrete wavelet transform (DWT) and the support vector machines (SVM). Features extracted from the DWFT coefficients are further used,SVM is trained to select the source image having the best focus at each pixel location, and this corresponding DWFT coefficients are then included into the composite wavelet representation. Among these wavelet decompositions, the wavelet coefficient having the largest magnitude is selected at each pixel location.Finally, author claims that, the fused image can be recovered by performing the inverse DWT whereas the wavelet function can be improved by applying discrete wavelet frame transform (DWFT) and support vector machine (SVM).Author claims, the experimental results show, ISSN: 2231-5381 http://www.ijettjournal.org Page 325 International Conference on Global Trends in Engineering, Technology and Management (ICGTETM-2016) the proposed method outperforms the traditional approach both visually and quantitatively. Sing et al. [5] reported that the quality of MRI gets affected by intensity in-homogeneities generated duringacquisition process which makes segmentation task more difficult. The paper proposed a method for segmentation of MRI using a fuzzy adaptive radial basis function neural network (FARBF-NN). The scholar used an interesting method, to eliminate theeffect of noise present in the input image using a fuzzy membership function which in turn modify the outputs of hidden layer neurons of the FARBF-NN. Study shows that the proposed method is better than the k-means clustering algorithm, the fuzzy c-means (FCM) clustering algorithm. The paper gave an idea that Hidden layer neuron of FARBF-NN neurons can be fuzzified to reduce noise effect. MG Di Bono et al.[6] describes a method based on Support Vector machines for Regression (SVR) to decode cognitive states from functional Magnetic Resonance Imaging (fMRI) data.Their focus is that a comprehensive methodology is required to explore the feasibility of the SVR Kernel-based approach for extremely complex regression problem.The authors created virtual environment to get subjective feature and objective measures. FMRI data was collected for prediction of ratings. For each subject, the need arises to predict feature separately.After applying SVM Regression, with the help of applying statistical measures to achieve enhanced performanceand generalizability. However, more accuracy can be achieved by statistical techniques such as sorting, distributions (chi-square, binomial).Moreover, virtual environment has its own shortcomings and special considerations are the major reason of inaccuracy. Yu et al. [7] proposed the methodology of segmenting an image into three parts, including dark, gray and white. For 2D histogram, Z-function and sfunction are used for fuzzy division. Afterwards, (Quantum Genetic Algorithm) QGA is applicable for finding combination of 12 membership parameters, which have maximum value. This technique enhances the image segmentation. The significance of their work is the use of three-level segmentation followed by maximum fuzzy partition of 2D Histograms. Proposed method is the selection of for optimal combination of parameters with the fuzzy partition entropy of 2D histogram.This generates better performance than one dimensional 3-level thresholding method. Somehow, it is not practically feasible as a large number of possible combinations of 12 parameters in a multi-dimensional fuzzy partition are used. Therefore, QGA can be used to find the optimal combination. ISSN: 2231-5381 M.Kumar et al.[8] reported that all automatic seed finding methods may suffer, if there is no growth of tumor and any small white portion present and when the edges of tumor is not sharped then the segmentation results over segmented or under segmented. This may occur due to initial stage of the tumors. Outranging this problem, author proposed method of tumor detection based on texture of the MRI. Their method is intended to help the surgeon to distinguish the involved area precisely by separating the irregularity from the regular surrounding tissue to get a real identification of involved and noninvolved area. The method used is texture analysis and seeded region growing method. It gives new, robust, fast and fully automatic algorithm where algorithm needs no prior information or training process. By taking into account both the homogeneous texture features and spatial features of the MRI, their work find the seed points and the segmentation results obtained are very much accurate. There are very few pixels which are misclassified. However, a limitation to this technique is that time consumption could be reduced. Roy et al.[9] proposed automatic brain tumor detection approach using symmetry analysis. The sequence of the methodology proposed in paper shows detection of tumor at the beginning then segmenting the area of interest and followed by area of tumor calculation.One of the important aspects is that after performing the quantitative analysis, we can identify the status of an increase in the disease. This Paper suggested multi-step and modular approached to solve the complex MRI segmentation problem.They proved that their algorithm can automatically detect and segment the brain tumor. Like most authors, the authors agree that MR imaging gives better result compare to other techniques like CT images and Xrays. To remove noise, image pre-processing isdone by converting RGB image into grayscale image and then passing that image to the high pass filter. Anam Mustaqeem et al. [10] emphasized efficient algorithm for tumor detection based on thresholdsegmentation and morphological operators. At First quality of scanned image is enhanced and then morphological operators are applied to detect the tumor in the scanned image. Additionally, the main logic is the selection of a threshold value. Previous Researched methods can be used under this segmentation, maximum entropy method and kmeans clustering method for segmentation. It gives interesting result, ability to detect the continuous boundary of the region of interest. It is easy to execute and manage thus applicable for high accuracy and precision is needed. The study concludes, selection of threshold value is difficult. However, Location of tumor can be specified easily using thresholding bydetermining an intensity value for specifying groups. http://www.ijettjournal.org Page 326 International Conference on Global Trends in Engineering, Technology and Management (ICGTETM-2016) J. Selvakumar et al. [11] paper described the implementation of Simple Cluster Algorithm for detection of range and shape of tumor in brain MRI.Proposed method combines the two computer aided methods for segmentation. At the end of the method, tumor is extracted from the MR image and its exact position and the shape is determined & the tumor’s stage is estimated based on the amount of area calculated from the cluster.The method proposed shows, if tumor has a mass then K- means algorithm is enough to extract it from the brain cells. And if there is any presence of noise in the MR image, it is removed before the K-means process. The noise free image is an input to the k-means and tumor is extracted from the MRI image followed by segmentation using Fuzzy C means for accurate tumor shape extraction. Thresholding is used as a last stage for feature extraction at the output.Finally, the author claims the approximate reasoning for calculating tumor shape and position calculation is required. The experimental results were compared with other algorithms and the proposed method is more accurate was proved. However, in future 3D assessment of brain using 3D slicers can be developed with matlab. Sonu Suhag et al.[14] paper proposed, like most of the researchers, work carried out for processing of MRI brain images for detection and classification of tumor and non-tumor image is done; however, here it is by using classifier. The image processing is carried out first by using any of the standard methods and then for segmentation Fuzzy C mean segmentation method, feature extraction using GLCM technique and SVM Classifier is used. Study shows that it will determine whether it is normal or abnormal. This combination gave accuracy of around 94% in classifying whether the MRI image is normal or abnormal. Hooda et al. [13] paper deals with theperformance analysis of image segmentation techniques such as K-Means Clustering, Fuzzy CMeans Clustering and Region Growing for detection of brain tumor.In this paper, performance evaluation of the above mentioned techniques is done based on error percentage as compared to ground truth. After comparing all the three methods it was concluded that the error percentage value was lowest with FCM clustering and it outperforms other segmentation algorithm. Ajala Funmilola A [15] focused attention onClustering methods, specifically k-means and fuzzy c-means clustering algorithms. The combination of these algorithms provides a novel proposed method called fuzzy k-c-means clustering algorithm, which has a better result in terms of time utilization.Time, accuracy, and iterations have been the major focus. Still, limitations like k-means segmenting withpredetermined number of clusters and Fuzzy Cmeansgenerating an overlapping results persist and not ISSN: 2231-5381 being able to segment colored images until they are convertedinto grey scale. Fuzzy K-C-Means also operates almost like FuzzyC-Means. Roopali R. Laddha et al. [17] paper proposed a method to detect brain tumor using medical imaging techniques. Techniques focused in this paper were Text- Noise Removal & segmentation which can include a method based onthreshold segmentation, watershed segmentation and morphological operators. The proposed segmentation method was experimented with MRI scanned images of human brains, thus locating tumor in the images. Samples of human brains were taken, scanned using MRI process and then wereprocessed through segmentation methods. Harneet Kaur and Sukhwinder Kaur [18] argued that the most of existing methods has ignored the poor quality images like images with noise or poor brightness.So to overcome these limitations, a new technique has been proposed. The comparison has shown that the proposed technique has achieved up to 94 % accuracy which was only 78 % in neural based technique. Also, for high corrupted noisy images the proposed technique has shown quite effective results than the neural based tumor detection. The study shows, work proposed uses new object based brain tumor detection and the decision based median filtering technique. Authors claim that their proposed method shows quite effective results than neural based tumor detection technique. Gauri et al.[16] paper reports a survey on different segmentation techniques applied to MR Images for locating tumor and a proposed method for the same using Fuzzy C-Means algorithm along with an algorithm to find area of tumor which is useful to decide type of brain tumor. By finding area of tumor we can decide type of tumor;whether it is benign or malignant. Khan [23] has widely researched and provide us with the efficient and impressive literature survey and validated the outcome that yet the field of research has vast to do get a perfect method for image segmentation because the result of image segmentation is dependent on many factors which varies with the method implemented. i.e., pixel color, texture, intensity, similarity of images, image content, and problem domain. Author also claim, it is good to use hybrid solution consists of multiple methods for image segmentation problem. Jin Liu et al. [19] provided a very interesting comprehensive overview for MRI-based brain tumor segmentation methods. The paper includes an introduction to brain tumors and imaging modalities of brain tumors, preprocessing operations and briefly explained the methods of MRI-based brain tumor segmentation. Moreover, the evaluation and validation of the results of MRI-based brain tumor http://www.ijettjournal.org Page 327 International Conference on Global Trends in Engineering, Technology and Management (ICGTETM-2016) segmentation are discussed. Finally, an objective assessment is presented and future developments and trends are addressed for MRI-based brain tumor segmentation methods. Although most of brain tumor segmentation algorithms have relatively good results in the field of medical image analysis, there is a certain distance in clinical applications. Due to a lack of interaction between researchers and clinicians, clinicians still rely on manual segmentation for brain tumor in many cases. Gaussian mixture models, wavelet based models, finite mixture models, fuzzy adaptive, many hybrid models, etc. Most of the researchers’ preferred MR images due to its advantages over other techniques such as MRI provides rich information about anatomical structure, enabling quantitative pathological or clinical studies. A critical review of the studied literature is summarized in the overview of segmentationtable. (Table 1). III CRITICAL EVALUATION In this study, we have seen different techniques for segmentation. The prominent intensity models studied in this paper include neural networks, TABLE- 1 COMPARISION OF SEGMENTATION METHODS Summary Proposed Technique Segmentation Zhang [1] (2001) of MRI images Hidden Markov Random FieldExpectation Maximization (HMRFEM)model Segmentation Ahmed[2](2002) of MRI images Bias-Field Estimation Segmentation Tolba[3] (2003) of MRI images GaussianMulti resolutionAnalysi s Fusing Li[4](2004) images Discrete Wavelet Transform (DWT) & Support Vector Machines (SVM) Segmentation J. K. Sing[5] of MRI images (2005) Neutral Network Algorithm Used Benefits Identified Problems Expectation Maximization It can encode both spatial and statistical properties of an image, HMRF is flexible model, Efficient result even with high level of noise, low image quality and large number of classes It produces better results for noisy images than the EM algorithm, Fast convergence, Overcomes intensity inhomogeneities in FCM Requires estimating threshold which is heuristic, Results not accurate most of the time, Time consuming, Expensive QGA is selected for optimal combination of parameters with the fuzzy partition entropy, Performance wise better than one dimensional 3-level thresholding method Practically not feasible (Bias-Corrected Technique is limited to a Fuzzy C- Mean) single feature input, BCFCM Incorporation of spatial Algorithm constraints into /Modified theclassification blurs Fuzzy C-Mean some fine details Expectation Performance wise GMEM is Rarely preserve edges, Maximization better than EM, Less sensitive Produces misclassification to noise, Used in many at boundaries between medical techniques classes Discrete Technique uses enhanced Wavelet frame version of DWT, Relatively transform easy to implement, More accurate, It is not affected by consistency verification and activity level measurements Fuzzy Adaptive It removes effect of noise, Only one task related to radial basis Preserving sharpness of fusion can be done function image, Better result than K(FARBF-NN ) mean and FCM method Support Vector It uses statistical technique Inaccurate due to virtual Regression environment. Decoding Cognitive States MG Di Bono[6] (2008) Meanintensity Three-level Image Segmentation Yu[7] (2008) Quantum Fuzzy partition Genetic entropy of 2D Algorithm histogram and ( QGA ) geneticalgorithm ISSN: 2231-5381 http://www.ijettjournal.org Page 328 International Conference on Global Trends in Engineering, Technology and Management (ICGTETM-2016) Texture based segmentation from MRI images Kumar[8] (2011) Seeded Region growing method Segmentation Roy[9] (2012) of MRI images Modular approach Segmentation of MRI images Segmentation of MRI images Segmentation of MRI images Selva [11] (2012) Advanced KMean Clustering and Fuzzy CMean Algorithm Anam [10] (2012) Combination of threshold and watershed segmentation Funmilola [12] (2012) Fuzzy k-cmeans Clustering Algorithm Segmentation of MRI images Kaur (2014)[18] Object Based Brain tumor segmentation Segmentation Gauri[16] (2013) of MRI Fuzzy C-Means images Segmentation Segmentation Barbudhe (2014) of MRI [12] Gaussian images Multi resolution EM algorithm Segmentation Hooda (2014)[13] of MRI K-Means, Fuzzy images C-Means Clustering and Region Growing Segmentation Suhag (2015)[14] of MRI Fuzzy C mean images segmentation method IV CONCLUSION Seeded Region growing algorithm Determines the abnormality presence, Fully automatic algorithm, no prior information or training process needed. Automatically detect different types of brain tumors with anefficient results, uses quantitative analysis. Time consuming, Few pixels which are misclassified Faster realization, Exact shape and position is determined complex Methodology Useful for image binarization, to locate of tumor, able to detect continuous boundary of the region of interest, Easy to execute and manage, obtain high accuracy and precision. Selection of threshold value is difficult K-Mean clustering is followed by FCM Time, accuracy, and iterations have been the major focus object based brain tumor segmentation Reduces the problem of noise and gives accurate result Predetermined number of clusters, FCM generates overlapping results, Not able to segment colored images. can be further improved with Fuzzy technique FCM algorithm Good Accuracy, Automatic method Expectation Maximization Algorithm Utilizes the spatial correlation between neighboring pixels, reduces computational complexity, high reliability. The error percentage value was lowest with FCM clustering and it outperforms other segmentation algorithm. Symmetry analysis(waters hed and threshold segmentation) Simple Cluster Algorithm (KMean + FCM) Thresholding (feature extract) maximum entropy, kmeansclustering method and morphological tools K-Means, Fuzzy C-Means and Region Growing Algorithm Combination of FCM algorithm, GLCM & SVM technique Radiologists useMRI as medical imaging technique and for visualization of the internal structure of the body. Good sort of information related to human brain soft tissue anatomy, useful for diagnosis of brain tumor can be obtained easily. Further, MR images are used to analyze and study behavior of the brain.In diagnosis, image segmentation is inseparable part for tumor detection and till date many researchers have work upon it from more than decades. The contribution of all the ISSN: 2231-5381 Determines the abnormality presence, The combination give accuracy of around 94% Time consuming, Tedious Poor contrast, Noise and intensity in-homogeneities can affect the results It generates many misclassified pixels - - intelligent and novel work is tremendous in this field but yet a method is not sufficient to detect and segment the complex anatomy of brain with approximately 120 different types of tumors. From studies, we deduce that a hybrid method seems to be the only solution for getting a universal method for tumor segmentation. Many work on 3D space is performed, with the view to overcome the issues leading to the increase in complexity of the method and slower computational time.Due to the complexity and understanding the sensitivity and robustness of the tumor detection for a life of patient, http://www.ijettjournal.org Page 329 International Conference on Global Trends in Engineering, Technology and Management (ICGTETM-2016) applications, ISSN 2224-5782,ISSN 2224-0506. Vol 2, no.6, 2012 [16] Gauri P. Anandgaonka and Ganesh.S.Sable― Detection andidentification of brain tumor in brain MR images using ACKNOWLEDGMENT Fuzzyc-means segmentation, international journal of advanced research in computer and communication engineering vol. 2, I would like to thank my guide, issue 10, october 2013 Dr.S.R.Suralkarand supporting staff of SSBT E&TC [17] Miss. Roopali R. Laddha and Dr. Siddharth A. 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