SCRIPPS DISCOVERS
Ac cel e ra tin g D is co ve r i es , S a v i ng L ive s
A Newsletter for Philanthropists Published Quarterly by The Scripps Research Institute
VOL 5 • NO 4 • FALL 2009
California-Florida
I N S T I T U T E U P D AT E
Chris T. Sullivan and Leanna Landsmann
to Lead Scripps Florida Council
> Businessman and philanthropist Chris T. Sullivan, chairman of OSI Restaurant Partners, Inc.,
which includes the Outback Steakhouse chain, and editor, publisher, and educator Leanna Landsmann
have been named co-chairs of the newly formed Scripps Florida Council.
As co-chairs, they will help to recruit and lead a group of prominent individuals from various sectors who will assist the
biomedical research facility in Jupiter seek support from others throughout the state and nation.
“Scripps Florida’s research contribution to the betterment of human health can be limitless,” Sullivan said on accepting the
volunteer position. “But great science takes substantial support. I want to make sure Scripps Florida has the wherewithal to
make the discoveries that lead to the new drugs and treatments to fight life-threatening diseases like cancer, stroke, Alzheimer’s,
diabetes, and addiction.”
“We can make a difference in the lives of so many people, worldwide, by supporting the groundbreaking research that takes
place within the laboratories of Scripps Florida,” said Landsmann on joining the council leadership. “Cures and treatments for
diseases must be built on a foundation of biomedical research. That’s what Scripps Florida does, perhaps better than any other
institution, and all of us must support it.”
Scripps Florida is a division of The Scripps Research Institute. It specializes in basic biomedical research, developing and
using advanced technologies to accelerate drug development. Its 350,000 square-foot, state-of-the-art research facilities are
located adjacent to the Jupiter campus of Florida Atlantic University.
continued on page 2
Inside:
3 . . . Researchers Discover Genetic Clues
about Formation of Cancer Tumors
4 . . . Scientist Profile: Kristin Baldwin
5 . . . Donor Profile: Esther B. O’Keeffe
R E S E A R C H U P D AT E
Scientists Uncover a Novel Mechanism
Controlling Tumor Growth in the Brain
Charitable Foundation
Presidential Awards
7 . . . Laura Bohn Wins Young
Investigator Award
7 . . . Dix Wins California Breast Cancer
Research Program Grant
7 . . . Wahlestedt and Bannister Win
NIAAA Grant
7 . . . Scientists Win American Heart
Association Fellowships
BACK COVER: Congrats to Florida Student
and Teacher Interns, We Need Your Monthly
Support, Contact Us
s survival rates among some patients with
cancer continue to rise, so does the spread of
these cancers to the brain—as much as 40
percent of all diagnosed brain cancers are considered
metastatic, having spread from a primary cancer
elsewhere in the body.
Now, scientists from The Scripps Research Institute
have discovered a molecular mechanism that plays a
pivotal role in controlling cancer growth in the brain.
The discovery could provide a basis for potentially
effective therapies for the treatment of brain metastasis.
continued on page 2
A
6 . . . Scripps Research Scientists Win
Associate Professor
Brunhilde Felding-Habermann
Florida Council,
CONTINUED
“When Chris and Leanna agreed to lead the Council, I
was delighted,” said Scripps Research President Richard A.
Lerner. “Scripps Florida, and the Council, will benefit greatly
from their experience and leadership. Scientific research is
expensive and federal funds so restrictive that we must tap
the philanthropic heart of Florida and the nation. Chris and
Leanna will open doors, make our strong case to donors, and
lend their great enthusiasm and energy to our efforts.”
“Great science takes substantial support. I want to
make sure Scripps Florida has the wherewithal to
make the discoveries that lead to the new drugs
and treatments to fight life-threatening diseases.”
– Chris Sullivan, co-chair, Scripps Florida Council
Sullivan is no stranger to Scripps Florida. He was appointed
by former Governor Jeb Bush in 2004 to the board of the
Scripps Florida Funding Corporation, the entity created by
Florida to oversee the disbursement of a one-time investment
of $310 million in state funds to The Scripps Research
Institute for the establishment of Scripps Florida. He later
served as chair of the Funding Corp. board.
He directs much of his philanthropic giving through the
Chris T. Sullivan Foundation. Sullivan serves numerous
organizations in various positions including Florida Council
of 100 Executive Committee, the Florida Chamber of
Commerce; Board of Directors for the Florida Council on
Economic Education, Lowry Park Zoological Endowment
Foundation; Chairman's Board of Big Brothers Big Sisters of
America; the Advisory Board for the Salvation Army; and
Vice Chairman for Scripps Florida Funding Board; and the
Employment Policies Institute.
Sullivan will be joined by newly named volunteer co-chair,
Jupiter resident Leanna Landsmann, a nationally-recognized
Tumor Growth,
education writer and editor with broad publishing experience.
Landsmann helped to launch TIME Magazine For Kids
and was its president from 1997 to 2004. In 1999, she was
inducted into the EdPress Hall of Fame. She was awarded
TIME’s Henry Luce Leadership Award in 2000.
“Life-improving scientific breakthroughs that children
will one day read about in history books are coming from the
labs at Scripps Florida. Funding the work of Scripps research
scientists’ offers a great opportunity to those who want their
philanthropic efforts to leave a lasting contribution,” said
Landsmann. “Scripps Florida is fast becoming a key driver
of our region’s economy and a catalyst for high standards in
science education. Area residents can be very proud that
Scripps Florida has arrived in the neighborhood.”
The Scripps Florida Council has been formed to attract
volunteer leaders who will bring valuable networks of friends
and a broad range of expertise to help Scripps Florida to
accelerate and enhance its results. By serving as ambassadors
and advocates for Scripps Florida in their various business
and social communities, Council members can extend the
reach of staff and Trustees. Central to the mission of the
Council is to introduce Scripps Florida to people interested in
advancing biomedical research, and to get them involved in
supporting the scientific efforts underway on both campuses.
A key role of the Council will be to develop specific
initiatives designed to promote Scripps Florida in the
philanthropic community. Other roles include hosting small
events for donors and prospects and participating in an annual
flagship event promoting Scripps Florida. The Council will
also advise the administration and Trustees concerning the
impact of program and policy initiatives upon operations of
the Florida site. Those interested in knowing more about the
Council’s activities may contact Will Melton, Vice President
for Philanthropy, Scripps Florida, (562)-228-2018 or
wmelton@scripps.edu
CONTINUED
“Our study could have a broad impact because it explains
at a molecular level how metastatic lesions thrive in the brain,”
said Scripps Research Associate Professor Brunhilde FeldingHabermann, who led the research. “This offers a potential
target for inhibiting the growing problem of brain metastasis.”
For tumor cells that have invaded the brain, FeldingHabermann and her colleagues found that when activated, a
tumor cell receptor known as integrin αvβ3 increased the supply
of a growth factor involved in the development of new blood
vessels (“angiogenesis”) necessary for tumor expansion within
the brain tissue. In contrast, the same receptor did not influence
tumor growth at the primary cancer site, in this case, the breast.
2 | SCRIPPS DISCOVERS
FALL 2009
“The fact that we uncovered a link between activated αvβ3
and angiogenesis is quite striking,” said Senior Research
Associate Mihaela Lorger, the first author of the study. “In
addition, our study showed that that the ability of tumor cell
αvβ3 to enhance angiogenesis depends very much on the
microenvironment.”
This receptor’s varying effects on tumor cells depending
on their location in the body reinforces a principle that the
Felding-Habermann lab uncovered a few years ago.
“For tumor cells, it’s not just the presence of the receptor
on the cells, but the conformation or shape of the molecule
that determines how well tumor cells can do within different
continued on next page
R E S E A R C H U P D AT E
Researchers Discover Genetic Clues about
Formation of Cancer Tumors
> A new research study provides previously unknown genetic clues into how cancerous tumors
form in the human breast, brain, and colorectal system.
he findings were made by researchers at the
Scripps Translational Science Institute (STSI), a
collaboration between The Scripps Research
Institute and Scripps Health.
In the new study, research scientist Ali Torkamani and
Professor Nicholas Schork analyzed genetic data from
44 breast cancer, colorectal cancer, and glioblastoma tumors
and identified specific mutations (changes in a cell’s DNA)
within groups of genes that are strongly involved in
tumor formation.
While a large number of mutations occur within any tumor,
not all of them contribute directly to the tumor’s growth.
T
Some mutations are akin to “random noise” while
other mutations cause a growth advantage for
tumors. The new study differentiated between the
random and causative mutations.
“Understanding which specific mutations cause a tumor
to form is an important step that may potentially translate
into a more personalized approach to treating cancer
patients,” said Torkamani. “These mutations provide us
with targets for drug development that presumably would
be more efficient at killing cancer, with lower toxicity levels
that are safer for patients.”
Tumor Growth,
The new study builds
upon earlier research
conducted by Johns Hopkins
University scientists, who
sequenced cancerous tumors
and studied individual genes
linked to tumor growth.
Because tumors form in many
different ways, the scientists
designed their research to
look at groups of genes.
The Schork laboratory
focuses on the development
Professor Nicholas Schork
and implementation of
analysis methods for
understanding the genetic determinants of complex human
traits and diseases such as cancer, neuropsychiatric disease,
and cardiovascular disease. These methods focus on the
design, integration, and interpretation of studies making use
of contemporary high throughput genomic technologies.
The research was supported by the National Institutes of
Health, Scripps Genomic Medicine, a Scripps Translational
Sciences Institute Clinical Translational Science Award,
and a fellowship to Torkamani from The Donald C. and
Elizabeth M. Dickinson Foundation.
CONTINUED
tissues” Felding-Habermann said. “The shape of the
molecule can increase or reduce the receptor’s affinity for its
natural ligands.”
In the new study, which was conducted in mouse models,
the scientists showed that activated αvβ3 on tumor cells leads
to angiogenesis in the brain by elevating the expression of
the VEGF, a protein that is critical to the formation of new
blood vessels.
Tumor cells normally try to recruit more blood vessels
when oxygen supply runs low. When oxygen and nutrients
get scarce, many tumor cells die and tumor growth slows
down until new vessels have formed. But in the brain,
activated αvβ3 promotes rapid tumor growth by enabling
tumor cells to attract new blood vessels continuously, even
when oxygen is still abundant.
The scientists plan to follow up on their new findings by
testing if activated αvβ3 on tumor cells also supports brain
metastasis of other types of cancer, and by investigating if
targeting the activated form of αvβ3 can inhibit metastatic
brain disease.
The study was supported by The National Institutes of
Health, the University of California Breast Cancer Research
Program, Susan G. Komen Breast Cancer Foundation, and
the Government of Sweden.
SCRIPPS RESEARCH INSTITUTE
| 3
SCIENTIST PROFILE
Kristin Baldwin — Milestone Stem Cell Work that Opens
the Door to Exciting New Therapies
ristin Baldwin, as Assistant Professor in Scripps
Research’s Department of Cell Biology, uses cuttingedge stem cell technology, such as reprogramming
and cloning, and genetic engineering, to understand the
brain and the causes of neurological diseases, like Alzheimer’s,
Parkinson’s, and schizophrenia. Her fascinating work is
geared toward creating new disease models to better understand
disease causes and rapidly identify potential treatments.
Her team at Scripps Research received recent notoriety
for their breakthrough work in breeding live mice from
mouse skin cells, advancing a technique that could offer an
alternative to the controversial use of embryonic stem cells.
The work which was reported by the journal, Nature, involved
reprogramming normal cells to create what are known as
induced Pluripotent Stem Cells (IPS). Scientists had been
trying to produce mice with induced pluripotent cells for
several years.
K
Assistant Professor
Kristin Baldwin
The milestone work opens the door to the development
of exciting therapies, such as using a patient’s own cells to
grow replacement organs.
Two teams of Chinese researchers also recently reported
success in similar experiments, creating mice that were as
much as 95 percent genetically matched to the adult mouse
whose cells were used. But Kristin and her group’s techniques
appeared more effective in one key respect – the success rate
with which they produced live mice. Her best cell line
4 | SCRIPPS DISCOVERS
FALL 2009
produced live pups 13 percent of the time, compared with 3.5
percent and 1 percent reported by the Chinese groups.
“Reprogramming by iPS cell technology is one of the
most exciting areas in research right now,” said Kristin,
“because these experiments challenge fundamental
paradigms of basic biology and, at the same time, contribute
to a technology that offers enormous potential for
therapeutic advances.”
The breakthrough opens the enticing possibility that
iPS cells might be manipulated to grow replacement organs
such as hearts and livers, or to provide healthy replacements
for damaged cells, such as neurons to cure paralysis,
Parkinson’s, or Alzheimer’s disease. Because such cells
would be derived directly from the patient, the rejection
problems that plague conventional transplant therapies
would be eliminated. Another hope is that iPS cells will
be used to create new disease models that will foster
better understanding of disease causes and more rapid
identification of potential treatments.
“The work was very rewarding and I think it’s the wave
of the future in terms of investigating the cause of disease,”
said Kristin. “It overturns what we previously believed about
developmental biology and shows that our preconceived
notions may have been wrong. From it, we now have a
platform for new experiments and the technology offers the
field the possibility of finding new cures for diseases.”
Kristin credits a combination of hard work and teamwork
for her group’s success in moving the technology forward
at a record pace. This included many young graduate and
postdoctoral students, who worked seven days a week around
the clock for four months. She also emphasizes a close
collaboration with Sergey Kuprianov, Ph.D., who heads
Scripps Research’s Mouse Genetics core.
“The team refused to admit defeat,” said Kristin.
“Science is 99 percent failure and you only
succeed once every few years, but the successes
keep you going.”
Her work on cloning began while she was a postdoctoral
fellow at Columbia University working in the laboratory of
Nobel Laureate Dr. Richard Axel, where she cloned an
entire mouse from a single neuron from its nose – something
no one had ever done before. The experiment pays homage
continued on back page
DONOR PROFILE
The Esther B. O’Keeffe Charitable Foundation —
Funding Treatments and Cures for the Benefit of Mankind
rthur O’Keeffe, a surgeon and
longtime resident of Palm
Beach, who passed away in
April, was a respected physician and
generous philanthropist.
Dr. O’Keeffe taught at Harvard
Medical School, helped establish plastic
and practical reconstructive surgical
techniques which he had developed in
the Army, and served as a general surgeon
at Massachusetts General Hospital.
As importantly, he donated to various
artistic and medical causes, and instilled
his philanthropy in his children. The
Esther B. O’Keeffe Art Gallery at The
Society of the Four Arts in Palm Beach
and a speaker series are named for his
late wife, who died in 2002. Good
Samaritan and St. Mary’s medical
centers have pavilions in her name. In
2003, the American Heart Association
A
dedicated its new headquarters in West
Palm Beach in her name.
Dr. O’Keeffe also supported
Massachusetts General Hospital,
Cape Cod Hospital, and many other
charities too numerous to name. He
was one of the founding donors of the
Georgia O’Keeffe Museum of Santa
Fe, New Mexico. Dr. O’Keeffe’s father,
Daniel, was a cousin to renowned
artist Georgia O’Keeffe.
Dr. O’Keeffe’s children, Arthur,
Brian, Daniel, and Clare, all live in
Palm Beach, and they are carrying on
their father’s tradition by serving as
trustees of the Esther B. O’Keeffe
Charitable Foundation, established by
Dr. O’Keeffe and his wife in 1990.
It funds a broad spectrum of arts and
cultural programs, as well as health
and medical research causes.
According to Clare O’Keeffe, her
father was a gracious, highly educated
man, and a brilliant doctor. “He was a
big believer in genomics and the role
that genes play in the treatment and
prognosis of disease. He was a forward
thinker, ahead of his time.”
The foundation has an interest in
stem cell research and has supported
stem cell work at several institutions.
It recently funded stem cell work at
Scripps Research performed by scientists
Jeanne Loring, Sheng Ding, and
Kristin Baldwin. The funding helped
advance a recent breakthrough by
Dr. Baldwin that involved breeding live
mice from mouse skin cells, a technique
that could offer an alternative to the
controversial use of embryonic stem
cells, and means that the ability to treat
diabetes, Alzheimer’s, Parkinson’s,
hearing loss, or spinal cord damage with
a patient’s own cells is within reach.
“This is quite an exciting area to us,
to think you can actually cure someone
with diabetes and do it with their own
cells,” said Clare O’Keeffe. “We think
this is the way to go in medicine and
hope it will benefit everyone and lead
to cures. We’re thrilled to be supporting
Scripps Research in this endeavor.”
The late Dr. Arthur O’Keeffe (center)
with his children (left to right),
Daniel, Arthur, Clare, and Brian.
SCRIPPS RESEARCH INSTITUTE
| 5
AWARDS AND HONORS
Two Scripps Research Institute Scientists Win
Prestigious Presidential Early Career Awards
> Erica Ollmann Saphire and Marisa Roberto to Be Honored at the White House
wo scientists from The Scripps Research Institute—
Associate Professor Erica Ollmann Saphire, Ph.D.,
and Associate Professor Marisa Roberto, Ph.D.—have
been selected to receive a Presidential Early Career Award for
Scientists and Engineers, the highest honor bestowed by the
United States government on young professionals at the outset
of their independent research careers.
“These extraordinarily gifted young scientists and engineers
represent the best in our country,” said President Barack Obama
of the winners nationwide. “With their talent, creativity, and
dedication, I am confident that they will lead their fields in
new breakthroughs and discoveries and help us use science
and technology to lift up our nation and our world.”
“We are very proud of Erica and Marisa’s contributions to
their fields,” said Scripps Research President Richard A. Lerner,
M.D., “and we look forward to their next accomplishments.”
The Presidential Early Career Awards are intended to
recognize and nurture some of the finest scientists and engineers
who, while early in their research careers, show exceptional
potential for leadership at the frontiers of scientific knowledge
during the 21st century.
The award winners are selected based on two criteria:
innovative research at the frontiers of science and technology,
and community service demonstrated through scientific
leadership, education, or community outreach.
T
Associate Professor
Erica Ollmann Saphire
Associate Professor
Marisa Roberto
6 | SCRIPPS DISCOVERS
FALL 2009
Ollmann Saphire, who is a member of the Scripps Research
Department of Immunology and Microbial Sciences and The
Skaggs Institute for Chemical Biology, is a 2000 graduate of
the Scripps Research Ph.D. program, the Kellogg School of
Science and Technology. She received her undergraduate
degree from Rice University. Earlier this year, Ollmann
Saphire was awarded the prestigious Burroughs Wellcome
Fund Investigator in the Pathogenesis of Infectious Disease
award, which supports the career of a researcher who is
working on understanding the interactions between human
host and infectious agent.
In her research program, Ollmann Saphire combines x-ray
crystallography, biochemistry, and immunology to analyze
proteins that play key roles in the pathogenesis of Ebola and
other viral hemorrhagic fevers; structures of these proteins
provide templates for vaccine design and enable rapid responses
to newly emerging forms of the viruses. Last year, Ollmann
Saphire and colleagues determined the structure of a critical
protein from the Ebola virus, which, though rare, is one of
the deadliest viruses on the planet killing between 50 and 90
percent of those infected.
Roberto, a member of the Scripps Research Committee
on The Neurobiology of Addictive Disorders, Pearson
Center for Alcohol and Addiction Research, and the Harold
L. Dorris Neurological Research Institute, received both her
B.A. (1996), and Ph.D. (2001) from the University of Pisa,
Italy. She joined Scripps Research in 2001. In 2005, Roberto
received the Young Investigator Award from the Research
Society on Alcoholism.
In her research program, Roberto uses in vitro
electrophysiological techniques to understand the effects
of drugs of abuse and neuropeptides on neuronal function
and synaptic transmission. Last year, Roberto and colleagues
published a study providing evidence that the drug gabapentin
affects certain components of the alcohol addiction cycle in
the brain, supporting the idea that the medication, which is
approved by the U.S. Food and Drug Administration for
treating seizures and pain, also holds potential for the
treatment of alcohol dependence.
As Presidential Early Career Award honorees, Ollmann
Saphire and Roberto will receive up to a five-year research
grant to further their scientific investigations. The ceremony
conferring the award will take place at the White House in
the fall.
Laura Bohn Wins 2009 Joseph Cochin
Young Investigator Award
aura Bohn, an associate professor in the Department of Molecular Therapeutics at
The Scripps Research Institute’s Florida campus, has been awarded the 2009 Joseph
Cochin Young Investigator Award for her outstanding early achievements in the
field of drug abuse. The award, which is sponsored by The College on Problems of Drug
Dependence, is given annually to a scientist under the age of 40.
L
“It’s a tremendous honor to be given this award,” Bohn said, "particularly because it comes
from The College on Problems of Drug Dependence, which has been a research leader in the
understanding, treatment and prevention of drug abuse. While I’m grateful for the recognition
of my work, this award is also a recognition of the continued importance of the study of drug
abuse and what that means for our society as a whole.”
Bohn accepted the award in June at the Plenary Session of the College’s 71st annual meeting,
which was held in Reno/Sparks, Nevada.
Associate Professor Laura Bohn
Claes Wahlestedt and Tom Bannister
Win NIAAA Grant
Scripps Florida’s Claes Wahlestedt, professor, and Tom Bannister, associate scientific director of medicinal chemistry at
the Translational Research Institute, have won a two-year grant from the National Institutes of Health’s National Institute on
Alcohol Abuse and Alcoholism (NIAAA) through the American Recovery and Reinvestment Act. In the project, titled
“Discovery and development of nociceptin receptor ligands in alcohol dependence,” the researcher team will study new agents
intended to curb alcohol craving by a novel, previously untried mechanism.
Melissa Dix Wins
California Breast Cancer
Research Program Grant
Jorg Grandl and Xiaofei
Zhang Win American Heart
Association Fellowships
Melissa Dix, a graduate student in the Scripps Research
Kellogg School of Science and Technology who is
working in the Cravatt lab, has been selected to receive a
California Breast Cancer Research Program grant. The
title of her project is “Substrate Profiling of Breast Cancer
Related Proteases.”
Research Associate Jorg Grandl of the Patapoutian lab and
Research Associate Xiaofei Zhang of the Jegla Lab have won
two-year American Heart Association Fellowships. Grandl
will pursue a project titled “Structure and Function of TRP
Channel Thermosensation.” Zhang will conduct a project
titled “The Function of Elk (KV12) Potassium Channels.”
SCRIPPS RESEARCH INSTITUTE
| 7
Congrats to Florida Student and
Teacher Interns
Kristin Baldwin,
CONTINUED
to Woody Allen’s film, Sleeper, a
slapstick comedy in which scientists
attempt to clone a dead dictator using
only his nose.
“Some of my interest in cloning
comes from the fact that this is a brandnew science,” said Kristin. “There’s an
attraction to succeeding where others
have not.”
Kristin’s breakthrough work was
supported by a prestigious Pew Scholars
award and through funding from the
California Institute of Regenerative
Medicine, the Esther B. O’Keeffe
Charitable Foundation and the
Whitehall Foundation in Palm Beach,
and the Shapiro Family Foundation in
Beverly Hills.
Congratulations to the graduating class of Scripps Florida’s 2009 Student and
Teacher Summer Interns. This science education outreach program is generously
supported by the William R. Kenan, Jr. Charitable Trust. The 2009 class represents
the first summer interns to graduate from the new Scripps Florida Campus.
We Need Your Monthly Support
“We are so appreciative to
everyone who supported this
work,” said Kristin. “This type
of high risk, groundbreaking
research would not have been
possible otherwise.”
t Scripps Research, the work we do today is vital for developing tomorrow’s
cures. But medical miracles take time. Scripps Research relies on your
continued support throughout the lifesaving process of bringing science
from the lab to the bedside. Become a monthly donor and join us for the long haul!
You know that the research done at Scripps Research can unlock the cures for
deadly diseases. But did you know that it takes years of tireless, dedicated biomedical
research, before our findings can be turned into lifesaving drugs?
Scripps Research relies on monthly donations to sustain this critical work. Your
monthly gift provides the sustained income we need to see our research transformed
into groundbreaking new pharmaceuticals.
Become a monthly donor and your gift will automatically be transferred from
your credit or debit card each month, providing a fast, easy and secure way for you to
join Scripps Research in our work.
Please become a monthly donor and partner with us to save lives. To donate, go
to www.supportscrippsresearch.org, click on “Donate Now”, then click on “Donate
Monthly.” Our thanks to you.
Kristin is also involved in exposing
underprivileged students to science in
a most accessible way. In collaboration
with artist Amy Chase Gulden, she has
genetically engineered living, growing
paintings using E. coli bacteria as paint.
The team’s work was performed with
high school students in the Harlem
DNA Lab, and funded by the World
Science Festival. The resulting prints of
vines, trees, and other natural elements
mounted in glass petri dishes was recently
exhibited at the Serrano Contemporary
gallery in New York City in a show
entitled, Growing Impressions.
A
Contact Us:
• For more information about Scripps Research,
visit our web page at www.supportscrippsresearch.org
• To learn more about supporting Scripps Research’s
cutting-edge research, please contact:
California
(858) 784-7083 or (800) 788-4931
wkeeney@scripps.edu
Florida
(561) 228-2013
abruner@scripps.edu